Analogs of the CLV3 peptide: Synthesis and structure-activity relationships focused on proline residues

Plant and Cell Physiology

Volumn 52, Issue 1, 2011, Pages 30-36

  Kondo, Tatsuhiko ^a   Yokomine, Kenjiro ^a   Nakagawa, Aya ^a   Sakagami, Youji ^a  

^a NAGOYA UNIVERSITY   (Japan)

Author keywords

Arabidopsis thaliana; CLV3; Peptide hormone; Structureactivity relationship

Indexed keywords

ARABIDOPSIS PROTEIN; CLV3 PROTEIN, ARABIDOPSIS; PEPTIDE FRAGMENT; PROLINE;

ARTICLE; CHEMISTRY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ARABIDOPSIS PROTEINS; PEPTIDE FRAGMENTS; PROLINE; STRUCTURE-ACTIVITY RELATIONSHIP;

ARABIDOPSIS; ARABIDOPSIS THALIANA; BRASSICA OLERACEA VAR. BOTRYTIS;

EID: 79251522889     PISSN: 00320781     EISSN: 14719053     Source Type: Journal    
DOI: 10.1093/pcp/pcq146     Document Type: Article

References (17)

1. Brandts, J.F., Halvorson, H.R. and Brennan, M. (1975) Consideration of the possibility that the slow step in protein denaturation reactions is due to cis-trans isomerism of proline residues. Biochemistry 1 4 : 4953-4963.
2. Cheng, H.N. and Bovey, F.A. (1977) Cis-trans equilibrium and kinetic studies of acetyl- L -proline and glycyl- L-proline. Biopolymers 1 6 : 1465-1472.
3. Cock, J.M. and McCormick, S. (2001) A large family of genes that share homology with CLAVATA3. Plant Physiol. 126: 939-942.
4. Fletcher, J.C., Brand, U., Running, M.P., Simon, R. and Meyerowitz, E.M. ( 1999 ) Signaling of cell fate decisions by CLAVATA3 in Arabidopsis shoot meristems. Science 283: 1911-1914.
5. Fowler, S.A. and Blackwell, H.E. (2009) Structure-function relationships in peptoids: recent advances toward deciphering the structural requirements for biological function. Org. Biomol. Chem. 7 : 1508-1524.
6. Ito, Y., Nakanomyo, I., Motose, H., Iwamoto, K., Sawa, S., Dohmae, N., et al. (2006) Dodeca-CLE peptides as suppressors of plant stem cell differentiation. Science 313: 842-845.
7. Kondo, T., Nakamura, T., Yokomine, K. and Sakagami, Y. (2008) Dual assay for MCLV3 activity reveals structure-activity relationship of CLE peptides. Biochem. Biophys. Res. Commun. 377: 312-316.
8. Kondo, T., Sawa, S., Kinoshita, A., Mizuno, S., Kakimoto, T., Fukuda, H., et al. (2006) A plant peptide encoded by CLV3 identifi ed by in situ MALDI-TOF MS analysis. Science 313: 845-848.
9. Matsubayashi, Y., Ogawa, M., Morita, A. and Sakagami, Y. (2002) An LRR receptor kinase involved in perception of a peptide plant hormone, phytosulfokine. Science 296: 1470-1472.
10. Matsubayashi, Y. and Sakagami, Y. ( 2006 ) Peptide hormones in plants. Annu. Rev. Plant Biol. 57: 649-674.
11. Nguyen, J.T., Turck, C.W., Cohen, F.E., Zuckermann, R.N. and Lim, W.A. ( 1998 ) Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors. Science 282: 2088-2092.
12. Oelkers, K., Goffard, N., Weiller, G.F., Gresshoff, P.M., Mathesius, U. and Frickey, T. (2008) Bioinformatic analysis of the CLE signaling peptide family. BMC Plant Biol. 8: 1.
13. Ogawa, M., Shinohara, H., Sakagami, Y. and Matsubayashi, Y. (2008) Arabidopsis CLV3 peptide directly binds CLV1 ectodomain. Science 319: 294.
14. Ohyama, K., Shinohara, H., Ogawa-Ohnishi, M. and Matsubayashi, Y. ( 2009 ) A glycopeptide regulating stem cell fate in Arabidopsis thaliana. Nat. Chem. Biol. 5: 578-580.
15. Reimer, U., Scherer, G., Drewello, M., Kruber, S., Schutkowski, M. and Fischer, G. (1998) Side-chain effects on peptidyl-prolyl cis/trans isomerisation. J. Mol. Biol. 279: 449-460.
16. Trotochaud, A.E., Hao, T., Wu, G., Yang, Z. and Clark, S.E. (1999) The CLAVATA1 receptor-like kinase requires CLAVATA3 for its assembly into a signaling complex that includes KAPP and a Rho-related protein. Plant Cell 11: 393-406.
17. Xu, W., Harrison, S.C. and Eck, M.J. (1997) Three-dimensional structure of the tyrosine kinase c-Src. Nature 385: 595-602.