Generation of a specific polyclonal antibody with high affinity to atorvastatin and its employment in the development of elisa for determination of atorvastatin in plasma

Journal of Immunoassay and Immunochemistry

Volumn 32, Issue 1, 2011, Pages 57-69

  Darwish, Ibrahim A ^a   Al Obaid, Abdul Rahman M ^a   Al Malaq, Hamoud A ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

atorvastatin; ELISA; pharmacokinetic studies; plasma; polyclonal antibody; therapeutic monitoring

Indexed keywords

AMLODIPINE; ATORVASTATIN; DILTIAZEM; EZETIMIBE; FLUINDOSTATIN; LOSARTAN; MEVINOLIN; POLYCLONAL ANTIBODY; PRAVASTATIN; PROPRANOLOL; ROSUVASTATIN; SIMVASTATIN; VALSARTAN;

ACCURACY; ANIMAL EXPERIMENT; ANTIBODY SPECIFICITY; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG MONITORING; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIBODY FORMATION; ANTIBODY SPECIFICITY; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HAPTENS; HEPTANOIC ACIDS; PYRROLES; RABBITS; REPRODUCIBILITY OF RESULTS;

EID: 79251517411     PISSN: 15321819     EISSN: 15324230     Source Type: Journal    
DOI: 10.1080/15321819.2010.538109     Document Type: Article

References (33)

1. Kaufman, D. W. ; Kelly, J. P. ; Rosenberg, L. ; Anderson, T. E. ; Mitchell, A. A. Recent Patterns of Medication Use in the Ambulatory Adult Population of the United States: The Slone Survey. J. Am. Med. Assoc. 2002, 287, 337-344.
2. Block, J. H. ; Beale, J. M. . Organic Medicinal and Pharmaceutical Chemistry, 11th Ed. ; Lippincott Williams & Wilkins: New York, 2004; pp. 662, 663.
3. Bakker-Arkema, R. G. ; Davidson, M. H. ; Goldstein, R. J. ; Davignon, R. J. ; Isaacsohn, S. L. ; Weiss, S. R. ; Keilson, L. M. ; Brown,W. V. ; Miller, V. T. ; Shurzinske, L. J. Efficacy and Safety of a New HMG-CoA Reductase Inhibitor, Atorvastatin, in Patients with Hypertriglyceridemia. J. Am. Med. Assoc. 1996, 275, 128-133.
4. Shitara, Y. ; Sugiyama, Y. Pharmacokinetic and Pharmacodynamic Alterations of 3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) Reductase Inhibitors: Drug-Drug Interactions and Interindividual Differences in Transporter and Metabolic Enzyme Functions. Pharmacol. Ther. 2006, 112, 71-105.
5. Igel, M. ; Sudhop, T. ; Von-Bergmann, K. Metabolism and Drug Interactions of 3-Hydroxy-3-methylglutaryl Coenzyme A-Reductase Inhibitors (Statins). Eur. J. Clin. Pharmacol. 2001, 57, 357-364.
6. Erturk, S. ; Onal, A. ; Cetin, S. M. Analytical Methods for the Quantitative Determination of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Inhibitors in Biological Samples. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 2003, 15, 193-205.
7. Pasha, M. K. ; Muzeeb, S. ; Basha, S. J. S. ; Shashikumar, D. ; Mullangi, R. ; Srinivas, N. R. Analysis of Five HMG-CoA Reductase Inhibitors: Atorvastatin, Lovastatin, Pravastatin, Rosuvastatin and Simvastatin: Pharmacological, Pharmacokinetic and Analytical Overview and Development of a New Method for Use in Pharmaceutical Formulations Analysis and In Vitro Metabolism Studies. Biomed. Chromatogr. 2006, 20, 282-33.
8. Nirogi, R. ; Mudigonda, K. ; Kandikere, V. Chromatography-Mass Spectrometry Methods for the Quantitation of Statins in Biological Samples. J. Pharm. Biomed. Anal. 2007, 44, 379-387.
9. Novakova, L. ; Satinsky, D. ; Solich, P. HPLC Methods for the Determination of Simvastatin and Atorvastatin. Trends Anal. Chem. 2008, 27, 352-367.
10. Zarghi, A. ; Shafaati, A. ; Foroutan, S. M. ; Khoddam, A. A Simple and Rapid HPLC Method for the Determination of Atorvastatin in Human Plasma with UV Detection and Its Application to Pharmacokinetic Studies. Arzneimittel Forsch. 2005, 55, 451-454. (Pubitemid 41190747)
11. Bahrami, G. ; Mohammadi, B. ; Mirzaeei, S. ; Kiani, A. Determination of Atorvastatin in Human Serum by Reversed-Phase High-Performance Liquid Chromatography with UV Detection. J. Chromatogr. 2005, 826, 41-45. (Pubitemid 41446432)
12. Borek-Dohalsky, V. ; Huclova, J. ; Barrett, B. ; Nemec, B. ; Ulc, I. ; Jelinek, I. Validated HPLC-MS-MS Method for Simultaneous Determination of Atorvastatin and 2-Hydroxyatorvastatin in Human Plasma-Pharmacokinetic Study. Anal. Bioanal. Chem. 2006, 386, 275-285.
13. Hermann, M. ; Christensen, H. ; Reubsaet, J. L. Determination of Atorvastatin and Metabolites in Human Plasma with Solid-Phase Extraction Followed by LC-Tandem MS. Anal. Bioanal. Chem. 2005, 382, 1242-1249.
14. Darwish, I. A. Immunoassay Methods and Their Applications in Pharmaceutical Analysis: Basic Methodology and Recent Advances. Int. J. Biomed. Sci. 2006, 2, 217-235.
15. Gomez-Henz, A. ; Aguilar-Caballos, M. P. Stopped-Flow Fluorescence Polarization Immunoassay. Comb. Chem. High Throughput Screen 2003, 6, 177-182.
16. Pieniaszek, H. J. ; Davidson, A. F. ; Walton, H. L. ; Pinto, D. J. ; Olson, R. E. ; Reilly, T. M. ; Barrett, Y. C. A Double Antibody Radioimmunoassay for the Determination of XV459, the Active Hydrolysis Metabolite of Roxifiban, in Human Plasma. J. Pharm. Biomed. Anal. 2003, 30, 1441-1449.
17. Suzuki, Y. ; Arakawa, H. ; Maeda, M. The Immunoassay of Methotrexate by Capillary Electrophoresis with Laser-Induced Fluorescence Detection. Anal. Sci. 2003, 19, 111-115.
18. Kobayashi, N. ; Shibusawa, K. ; Kubota, K. ; Hasegawa, N. ; Sun, P. ; Niwa, T. ; Junichi, G. Monoclonal Anti-Idiotype Antibodies Recognizing the Variable Region of a High-Affinity Antibody Against 11-Deoxycortisol: Production, Characterization and Application to a Sensitive Noncompetitive Immunoassay. J. Immunol. Methods 2003, 274, 63-75.
19. Ito, K. ; Nakagawa, K. ; Murakami, S. ; Arakawa, H. ; Maeda, M. Highly Sensitive Simultaneous Bioluminescent Measurement of Acetate Kinase and Pyruvate Phosphate Dikinase Activities Using a Firefly Luciferase-Luciferin Reaction and Its Application to a Tandem Bioluminescent Enzyme Immunoassay. Anal. Sci. 2003, 19, 105-109.
20. Hermida, J. ; Boveda, M. D. ; Vadillo, F. J. ; Tutor, J. C. Comparison Between the Cobas Integra Immunoassay and High-Performance Liquid Chromatography for Therapeutic Monitoring of Carbamazepine. Clin. Biochem. 2002, 35, 251-254.
21. Zhao, X. ; Kottegoda, S. ; Shippy, S. Solid-Phase Immunoassay Detection of Peptides From Complex Matrices without a Separation. Analyst 2003, 128, 357-362.
22. Draisci, R. ; Quandri, F. ; Achene, L. ; Volpe, G. ; Palleschi, L. ; Palleschi, G. A New Electrochemical Enzyme-Linked Immunosorbent Assay for the Screening of Macrolide Antibiotic Residues in Bovine Meat. Analyst 2001, 126, 1942-1946.
23. Darwish, I. A. ; Al-Obaid, A. M. ; Al-Malaq, H. A. New Highly Sensitive Enzyme Immunoassay for the Determination of Pravastatin in Human Plasma. Talanta 2009, 79, 1478-1483.
24. Habeeb, A. F. Determination of Free Amino Groups in Proteins by Trinitrobenzenesulfonic Acid. Anal. Biochem. 1966, 14, 328-336.
25. Darwish, I. A. ; Al-Obaid, A. M. ; Al-Malaq, H. A. Preparation of a Highly Specific Polyclonal Antibody Against Fluvastatin and Its Use in the Development of ELISA in the Determination of Fluvastatin in Plasma. Anal. Methods 2009, 1, 220-224.
26. Weeks, I. In Chemiluminescence Immunoassay; Sevehla, G. , Ed. ; Elsevier: Amsterdam, 1992, Vol. XXIX, pp. 53-73.
27. Khosraviani, M. ; Blake, R. C. II; Pavlov, A. R. ; Lorbach, S. C. ; Yu, H. ; Delehanty, B. ; Brechbiel, M. W. ; Blake, D. A. Binding Properties of a Monoclonal Antibody Directed Toward Lead-Chelate Complex. Bioconj. Chem. 2000, 11, 267-277.
28. Mastronicolis, S. ; Kapoulas, V. ; Kröger, H. The Isolation of Specific Antibodies for 5-Methylcytidine- Bovine Serum Albumin. Z. Natureforsch, 1981, 36c, 459-463.
29. Hermida, R. C. ; Calvo, C. ; Ayala, D. E. ; Lopez, J. E. OR-6: Administration Time-Dependent Efficacy of Valsartan-Atorvastatin Combination in Hyperlipidemic Patients with Essential Hypertension. Am. J. Hypertens. 2005, 18, 2A-2A.
30. Eyal, L. ; Maya, B. ; Reuven, Z. ; Angela, F. ; Marina, S. ; Dov, G. Treatment with amLodipine and Atorvastatin have Additive Effect in Improvement of Arterial Compliance in Hypertensive Hyperlipidemic Patients. Am. J. Hypertens. 2003, 16, 715-718.
31. Stein, E. A. ; Ballantyne, C. M. ; Windler, E. ; Sirnes, P. A. ; Sussekov, A. ; Yigit, Z. ; Seper, C. ; Gimpelewicz, C. R. Efficacy and Tolerability of Fluvastatin XL 80mg Alone, Ezetimibe Alone, and the Combination of Fluvastatin XL 80mg with Ezetimibe in Patients with a History of Muscle-Related Side Effects with Other Statins. Am. J. Cardiol. 2008, 15, 490-496.
32. Anderson, D. J. Determination of the Lower Limit of Detection. Clin. Chem. 1989, 35, 2152-2153.
33. Findlay, J. W. ; Smith, W. C. ; Lee, J. W. ; Nordblom, G. D. ; Das, I. ; De Silva, B. ; SKhan, M. N. ; Bowsher, R. R. Validation of Immunoassays for Bioanalysis: A Pharmaceutical Industry Perspective. J. Pharm. Biomed. Anal. 2000, 21, 1249-1273.