Cardiovascular anomalies in turner syndrome: Spectrum, prevalence, and cardiac MRI findings in a pediatric and young adult population

American Journal of Roentgenology

Volumn 196, Issue 2, 2011, Pages 454-460

  Kim, Hee Kyung ^a   Gottliebson, William ^a   Hor, Kan ^a   Backeljauw, Philippe ^a   Gutmark Little, Iris ^a   Salisbury, Shelia R ^a   Racadio, Judy M ^a   Helton Skally, Kathy ^a   Fleck, Robert ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Cardiac MRI; Cardiovascular disease; Turner syndrome

Indexed keywords

ADOLESCENT; ADULT; AGE; AORTA COARCTATION; ARTICLE; BICUSPID AORTIC VALVE; BLOOD PRESSURE; BODY SURFACE; CARDIOVASCULAR MALFORMATION; CHILD; FEMALE; HEART RIGHT VENTRICLE VOLUME; HEART VENTRICLE FUNCTION; HEART VENTRICLE SIZE; HUMAN; KARYOTYPE; LUNG VEIN DRAINAGE ANOMALY; MAJOR CLINICAL STUDY; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; TURNER SYNDROME;

ADOLESCENT; ADULT; CARDIOVASCULAR ABNORMALITIES; CHILD; COMORBIDITY; ELECTROCARDIOGRAPHY; FEMALE; HUMANS; HYPERTENSION; IMAGE ENHANCEMENT; INCIDENCE; MAGNETIC RESONANCE ANGIOGRAPHY; MAGNETIC RESONANCE IMAGING; PREVALENCE; RETROSPECTIVE STUDIES; TURNER SYNDROME; YOUNG ADULT;

EID: 79251484663     PISSN: 0361803X     EISSN: 15463141     Source Type: Journal    
DOI: 10.2214/AJR.10.4973     Document Type: Article

References (35)

1. Lemli L, Smith DW. The XO syndrome: a study of the differentiated phenotype in 25 patients. J Pediatr 1963; 63:577-588
2. Stochholm K, Juul S, Juel K, Naeraa RW, Gravholt CH. Prevalence, incidence, diagnostic delay, and mortality in Turner syndrome. J Clin Endocrinol Metab 2006; 91:3897-3902
3. Haddad HM, Wilkins L. Congenital anomalies associated with gonadal aplasia; review of 55 cases. Pediatrics 1959; 23:885-902
4. Mazzanti L, Prandstraller D, Tassinari D, et al. Heart disease in Turner's syndrome. Helv Paediatr Acta 1988; 43:25-31
5. Mazzanti L, Cacciari E. Congenital heart disease in patients with Turner's syndrome. Italian Study Group for Turner Syndrome (ISGTS). J Pediatr 1998; 133:688-692
6. Saenger P, Wikland KA, Conway GS, et al. Recommendations for the diagnosis and management of Turner syndrome. J Clin Endocrinol Metab 2001; 86:3061-3069 (Pubitemid 32673466)
7. Dawson-Falk KL, Wright AM, Bakker B, Pitlick PT, Wilson DM, Rosenfeld RG. Cardiovascular evaluation in Turner syndrome: utility of MR imaging. Australas Radiol 1992; 36:204-209
8. Masui T, Seelos KC, Kersting-Sommerhoff BA, Higgins CB. Abnormalities of the pulmonary veins: evaluation with MR imaging and comparison with cardiac angiography and echocardiography. Radiology 1991; 181:645-649
9. Ho VB, Corse WR, Hood MN, Rowedder AM. MRA of the thoracic vessels. Semin Ultrasound CT MR 2003; 24:192-216
10. Prince MR, Narasimham DL, Jacoby WT, et al. Three-dimensional gadolinium-enhanced MR angiography of the thoracic aorta. AJR 1996; 166:1387-1397 (Pubitemid 26160595)
11. Bondy CA. Care of girls and women with Turner syndrome: a guideline of the Turner Syndrome Study Group. J Clin Endocrinol Metab 2007; 92:10-25
12. Bondy CA. Turner syndrome 2008. Horm Res 2009; 71[suppl 1]:52-56
13. Lin AE, Lippe BM, Geffner ME, et al. Aortic dilation, dissection, and rupture in patients with Turner syndrome. J Pediatr 1986; 109:820-826
14. Ho VB, Bakalov VK, Cooley M, et al. Major vascular anomalies in Turner syndrome: prevalence and magnetic resonance angiographic features. Circulation 2004; 110:1694-1700
15. Sachdev V, Matura LA, Sidenko S, et al. Aortic valve disease in Turner syndrome. J Am Coll Cardiol 2008; 51:1904-1909
16. Lin AE, Silberbach M. Focus on the heart and aorta in Turner syndrome. J Pediatr 2007; 150: 572-574
17. Lanzarini L, Larizza D, Prete G, et al. Aortic dimensions in Turner's syndrome: two-dimensional echocardiography versus magnetic resonance imaging. J Cardiovasc Med (Hagerstown) 2007; 8: 428-437
18. Ostberg JE, Brookes JA, McCarthy C, Halcox J, Conway GS. A comparison of echocardiography and magnetic resonance imaging in cardiovascular screening of adults with Turner syndrome. J Clin Endocrinol Metab 2004; 89:5966-5971 (Pubitemid 39628401)
19. Castro AV, Okoshi K, Ribeiro SM, et al. Cardiovascular assessment of patients with Ullrich-Turner's syndrome on Doppler echocardiography and magnetic resonance imaging. Arq Bras Cardiol 2002; 78:51-58
20. Lin AE, Lippe B, Rosenfeld RG. Further delineation of aortic dilation, dissection, and rupture in patients with Turner syndrome. Pediatrics 1998; 102:e12
21. Kaiser T, Kellenberger CJ, Albisetti M, Bergstrasser E, Valsangiacomo Buechel ER. Normal values for aortic diameters in children and adolescents: assessment in vivo by contrast-enhanced CMR-angiography. J Cardiovasc Magn Reson 2008; 10:56
22. Surerus E, Huggon IC, Allan LD. Turner's syndrome in fetal life. Ultrasound Obstet Gynecol 2003; 22:264-267
23. Miyabara S, Nakayama M, Suzumori K, Yonemitsu N, Sugihara H. Developmental analysis of cardiovascular system of 45,X fetuses with cystic hygroma. Am J Med Genet 1997; 68:135-141 (Pubitemid 27081827)
24. Loscalzo ML, Van PL, Ho VB, et al. Association between fetal lymphedema and congenital cardiovascular defects in Turner syndrome. Pediatrics 2005; 115:732-735
25. Clark EB. Neck web and congenital heart defects: a pathogenic association in 45 X-O Turner syndrome? Teratology 1984; 29:355-361
26. Sybert VP. Cardiovascular malformations and complications in Turner syndrome. Pediatrics 1998; 101:E11
27. Smyth PT, Edwards JE. Pseudocoarctation, kinking or buckling of the aorta. Circulation 1972; 46:1027-1032
28. Subramaniam PN. Turner's syndrome and cardiovascular anomalies: a case report and review of the literature. Am J Med Sci 1989; 297:260-262 (Pubitemid 19104039)
29. Gravholt CH, Landin-Wilhelmsen K, Stochholm K, et al. Clinical and epidemiological description of aortic dissection in Turner's syndrome. Cardiol Young 2006; 16:430-436
30. Lim MS, Straus SE, Dale JK, et al. Pathological findings in human autoimmune lymphoproliferative syndrome. Am J Pathol 1998; 153:1541-1550
31. Kostich ND, Opitz JM. Ullrich-Turner syndrome associated with cystic medial necrosis of the aorta and great vessels: case report and review of the literature. Am J Med 1965; 38:943-950
32. Price WH, Wilson J. Dissection of the aorta in Turner's syndrome. J Med Genet 1983; 20:61-63
33. Bank ER, Aisen AM, Rocchini AP, Hernandez RJ. Coarctation of the aorta in children undergoing angioplasty: pretreatment and posttreatment MR imaging. Radiology 1987; 162:235-240
34. Bondy CA. Aortic dissection in Turner syndrome. Curr Opin Cardiol 2008; 23:519-526
35. Bondy CA, Van PL, Bakalov VK, Ho VB. Growth hormone treatment and aortic dimensions in Turner syndrome. J Clin Endocrinol Metab 2006; 91:1785-1788