Effect of deracoxib, a new COX-2 inhibitor, on the prevention of lameness induced by chemical synovitis in dogs

Veterinary Therapeutics

Volumn 3, Issue 4, 2002, Pages

  Millis, Darryl ^a,b   Weigel, Joseph ^a,b   Moyers, Tamberlyn ^a,b   Buonomo, Frances ^a,b   Kressin, Dale ^a,b  

^a MONSANTO COMPANY   (United States)

^b Novartis Animal Health   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANIS FAMILIARIS;

EID: 79251475919     PISSN: 15283593     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Urban MK: COX-2 specific inhibitors offer improved advantages over traditional NSAIDs. Orthopedics 23(suppl):S761"S764, 2000.
2. Pairet M, van Ryn J: Experimental models used to investigate the differential inhibition of cyclooxygenase-1 and cyclooxygenase-2 by non-steroidal anti-inflammatory drugs. Inflamm Res 47(suppl 2):S93"S101, 1998.
3. Kawakami M, Matsumoto T, Hashizume H, et al: Epidural injection of cyclooxygenase-2 inhibitor attenuates pain-related behavior following application of nucleus pulposus to the nerve root in the rat. J Orthop Res 20:376-381, 2002.
4. Smith CJ, Zhang Y, Koboldt CM, et al: Pharmacological analysis of cyclooxygenase-1 in inflammation. Proc Natl Acad Sci USA 95:13313-13318, 1998.
5. Camu F, Beecher T, Recker DP, Verburg KM: Valdecoxib, a COX-2-specific inhibitor, in an efficacious, opiod-sparing analgesic in patients undergoing hip arthroplasty. Am J Ther 9:43-51, 2002.
6. Chang YH: Studies on phagocytosis. II. The effect of nonsteroidal anti-inflammatory drugs on phagocytosis and on urate crystal-induced canine joint inflammation. J Pharmacol Exp Ther 183:235-244, 1972.
7. Cross AR, Budsberg SC, Keefe TJ: Kinetic gait analysis assessment of meloxicam efficacy in a sodium urate-induced synovitis model in dogs. Am J Vet Res 58:626-631, 1997.
8. Paul H, Clayburne G, Schumacher HR: Lidocaine inhibits leukocyte migration and phagocytosis in monosodium urate crystal-induced synovitis in dogs. J Rheumatol 10:434-439, 1983.
9. Phelps P, McCarty Jr DJ: Suppressive effects of indomethacin on crystal-induced inflammation in canine joints and on neutrophilic motility in vitro. J Pharmacol Exp Ther 158:546-553, 1967.
10. Rumph PF, Kincaid SA, Baird DK, et al: Vertical ground reaction force distribution during experimentally induced acute synovitis in dogs. Am J Vet Res 54:365-369, 1993.
11. Van Arman CG, Carlson RP, Risley EA, et al: Inhibitory effects of indomethacin, aspirin and certain other drugs on inflammations induced in rat and dog by carrageenan, sodium urate and ellagic acid. J Pharmacol Exp Ther 175:459-468, 1970.
12. Faires JS, McCarty DJ: Acute arthritis in man and dog after intrasynovial injection of sodium urate crystals. Lancet 2:682-684, 1962.
13. Samad TA, Moore KA, Sapirstein A, et al: Interleukin-1 beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature 410:471-475, 2001.
14. Svensson CI, Yaksh TL: The spinal phospholipase-cyclooxygenase-prostanoid cascade in nociceptive processing. Annu Rev Pharmacol Toxicol 42:553-583, 2002.
15. Rosenthale ME, Kassarich J, Schneider F: Effect of anti-inflammatory agents on acute experimental synovitis in dogs. Proc Soc Exp Biol Med 122:693-696, 1966.