Nonsense mediated decay resistant mutations are a source of expressed mutant proteins in colon cancer cell lines with microsatellite instability

PLoS ONE

Volumn 5, Issue 12, 2010, Pages

  Williams, David S ^a,b,c   Bird, Matthew J ^a   Jorissen, Robert N ^a   Yu, Yen Lin ^a   Walker, Franscesa ^a   Zhang, Hui Hua ^a   Nice, Edouard C ^a   Burgess, Antony W ^a  

^a LUDWIG INSTITUTE FOR CANCER RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c Melbourne Health ^*  (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 5; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; E1A ASSOCIATED P300 PROTEIN; EPITOPE; F BOX PROTEIN; PROTEIN BAX; PROTEIN MSH3; HLA A ANTIGEN; MICROSATELLITE DNA;

AMINO TERMINAL SEQUENCE; ARTICLE; CANCER CELL; CARBOXY TERMINAL SEQUENCE; COLON CANCER; CONTROLLED STUDY; EXON; FRAMESHIFT MUTATION; GENE IDENTIFICATION; GENE MUTATION; GENETIC CODE; GENETIC SCREENING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MICROSATELLITE INSTABILITY; MOLECULAR WEIGHT; NONSENSE MEDIATED MRNA DECAY; NONSENSE MUTATION; PROTEIN EXPRESSION; PROTEOMICS; BIOLOGY; COLON TUMOR; DNA REPAIR; EPITOPE MAPPING; GENE EXPRESSION REGULATION; GENETICS; GENOME; METHODOLOGY; MUTATION; PROTEIN TERTIARY STRUCTURE; STOP CODON; TUMOR CELL LINE;

CELL LINE, TUMOR; CODON, NONSENSE; COLONIC NEOPLASMS; COMPUTATIONAL BIOLOGY; DNA REPAIR; EPITOPE MAPPING; FRAMESHIFT MUTATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOME; HLA-A ANTIGENS; HUMANS; MICROSATELLITE INSTABILITY; MICROSATELLITE REPEATS; MUTATION; PROTEIN STRUCTURE, TERTIARY;

EID: 79251475891     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0016012     Document Type: Article

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