메뉴 건너뛰기




Volumn 123, Issue 22, 2010, Pages 3178-3183

Impact of CYP2C19 polymorphism and smoking on response to clopidogrel in patients with stable coronary artery disease

Author keywords

Clopidogrel; Coronary artery disease; CYP2C19; Smoking

Indexed keywords

ADENOSINE DIPHOSPHATE; CLOPIDOGREL; CYTOCHROME P450 2C19;

EID: 79251470415     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2010.22.002     Document Type: Article
Times cited : (14)

References (32)
  • 1
    • 0032797781 scopus 로고    scopus 로고
    • Pharmacokinetics of clopidogrel
    • H, Donat F, Gaud C, Necciari J. Pharmacokinetics of clopidogrel. Semin Thromb Hemost 1999; 25 Suppl 2: 25-28.
    • (1999) Semin Thromb Hemost , vol.25 , Issue.SUPPL. 2 , pp. 25-28
  • 2
    • 0028083293 scopus 로고
    • The antiaggregating activity of clopidogrel is due to a metabolic activation by the hepatic cytochrome P450-1A
    • Savi P, Combalbert J, Gaich C, Rouchon MC, Maffrand JP, Berger Y, et al. The antiaggregating activity of clopidogrel is due to a metabolic activation by the hepatic cytochrome P450-1A. Thromb Haemost 1994; 72: 313-317.
    • (1994) Thromb Haemost , vol.72 , pp. 313-317
    • Savi, P.1    Combalbert, J.2    Gaich, C.3    Rouchon, M.C.4    Maffrand, J.P.5    Berger, Y.6
  • 3
  • 5
    • 33749339075 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects
    • Hulot JS, Bura A, Villard E, Azizi M, Remones V, Goyenvalle C, et al. Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects. Blood 2006; 108: 2244-2247.
    • (2006) Blood , vol.108 , pp. 2244-2247
    • Hulot, J.S.1    Bura, A.2    Villard, E.3    Azizi, M.4    Remones, V.5    Goyenvalle, C.6
  • 6
    • 43049179414 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 681G>A polymorphism and high on-clopidogrel platelet reactivity associated with adverse 1-year clinical outcome of elective percutaneous coronary intervention with drug-eluting or bare-metal stents
    • Trenk D, Hochholzer W, Fromm MF, Chialda LE, Pahl A, Valina CM, et al. Cytochrome P450 2C19 681G>A polymorphism and high on-clopidogrel platelet reactivity associated with adverse 1-year clinical outcome of elective percutaneous coronary intervention with drug-eluting or bare-metal stents. J Am Coll Cardiol 2008; 51: 1925-1934.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 1925-1934
    • Trenk, D.1    Hochholzer, W.2    Fromm, M.F.3    Chialda, L.E.4    Pahl, A.5    Valina, C.M.6
  • 7
    • 58249135635 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: A cohort study
    • Collet JP, Hulot JS, Pena A, Villard E, Esteve JB, Silvain J, et al. Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study. Lancet 2009; 373: 309-317.
    • (2009) Lancet , vol.373 , pp. 309-317
    • Collet, J.P.1    Hulot, J.S.2    Pena, A.3    Villard, E.4    Esteve, J.B.5    Silvain, J.6
  • 9
    • 45249088224 scopus 로고    scopus 로고
    • The effect of CYP2C19 polymorphism on the pharmacokinetics and pharmacodynamics of clopidogrel: A possible mechanism for clopidogrel resistance
    • Kim KA, Park PW, Hong SJ, Park JY. The effect of CYP2C19 polymorphism on the pharmacokinetics and pharmacodynamics of clopidogrel: a possible mechanism for clopidogrel resistance. Clin Pharmacol Ther 2008; 84: 236-242.
    • (2008) Clin Pharmacol Ther , vol.84 , pp. 236-242
    • Kim, K.A.1    Park, P.W.2    Hong, S.J.3    Park, J.Y.4
  • 10
    • 0042357440 scopus 로고    scopus 로고
    • PM frequencies of major CYPs in Asians and Caucasians
    • Mizutani T. PM frequencies of major CYPs in Asians and Caucasians. Drug Metab Rev 2003; 35: 99-106.
    • (2003) Drug Metab Rev , vol.35 , pp. 99-106
    • Mizutani, T.1
  • 11
    • 0031427039 scopus 로고    scopus 로고
    • Direct evidence for the higher frequency of CYP2C19 allelic heterozygotes in Chinese subjects than in white subjects
    • Xie HG. Direct evidence for the higher frequency of CYP2C19 allelic heterozygotes in Chinese subjects than in white subjects. Clin Pharmacol Ther 1997; 62: 691-692.
    • (1997) Clin Pharmacol Ther , vol.62 , pp. 691-692
    • Xie, H.G.1
  • 12
    • 0033055995 scopus 로고    scopus 로고
    • Drug interactions with tobacco smoking. An update
    • Zevin S, Benowitz NL. Drug interactions with tobacco smoking. An update. Clin Pharmacokinet 1999; 36: 425-438.
    • (1999) Clin Pharmacokinet , vol.36 , pp. 425-438
    • Zevin, S.1    Benowitz, N.L.2
  • 13
    • 0032805239 scopus 로고    scopus 로고
    • Estimation of cytochrome P-450 CYP1A2 activity in 863 healthy Caucasians using a saliva-based caffeine test
    • Tantcheva-Poor I, Zaigler M, Rietbrock S, Fuhr U. Estimation of cytochrome P-450 CYP1A2 activity in 863 healthy Caucasians using a saliva-based caffeine test. Pharmacogenetics 1999; 9: 131-144.
    • (1999) Pharmacogenetics , vol.9 , pp. 131-144
    • Tantcheva-Poor, I.1    Zaigler, M.2    Rietbrock, S.3    Fuhr, U.4
  • 15
    • 49849097496 scopus 로고    scopus 로고
    • Smoking behaviour modulates pharmacokinetics of orally administered clopidogrel
    • Yousef AM, Arafat T, Bulatova NR, Al-Zumyli R. Smoking behaviour modulates pharmacokinetics of orally administered clopidogrel. J Clin Pharm Ther 2008; 33: 439-449.
    • (2008) J Clin Pharm Ther , vol.33 , pp. 439-449
    • Yousef, A.M.1    Arafat, T.2    Bulatova, N.R.3    Al-Zumyli, R.4
  • 16
    • 37549006004 scopus 로고    scopus 로고
    • The Residual Platelet Aggregation after Deployment of Intracoronary Stent (PREDICT) score
    • Geisler T, Grass D, Bigalke B, Stellos K, Drosch T, Dietz K, et al. The Residual Platelet Aggregation after Deployment of Intracoronary Stent (PREDICT) score. J Thromb Haemost 2008; 6: 54-61.
    • (2008) J Thromb Haemost , vol.6 , pp. 54-61
    • Geisler, T.1    Grass, D.2    Bigalke, B.3    Stellos, K.4    Drosch, T.5    Dietz, K.6
  • 17
    • 64649101414 scopus 로고    scopus 로고
    • Impact of clopidogrel resistance on thrombotic events after percutaneous coronary intervention with drug-eluting stent
    • Wang ZJ, Zhou YJ, Liu YY, Yu M, Shi DM, Zhao YX, et al. Impact of clopidogrel resistance on thrombotic events after percutaneous coronary intervention with drug-eluting stent. Thromb Res 2009; 124: 46-51.
    • (2009) Thromb Res , vol.124 , pp. 46-51
    • Wang, Z.J.1    Zhou, Y.J.2    Liu, Y.Y.3    Yu, M.4    Shi, D.M.5    Zhao, Y.X.6
  • 18
    • 0028289804 scopus 로고
    • New insights into the mechanisms of platelet adhesion and aggregation
    • Ruggeri ZM. New insights into the mechanisms of platelet adhesion and aggregation. Semin Hematol 1994; 31: 229-239.
    • (1994) Semin Hematol , vol.31 , pp. 229-239
    • Ruggeri, Z.M.1
  • 19
    • 0038291914 scopus 로고    scopus 로고
    • Prevalence of clopidogrel non-responders among patients with stable angina pectoris scheduled for elective coronary stent placement
    • Muller I, Besta F, Schulz C, Massberg S, Schonig A, Gawaz M. Prevalence of clopidogrel non-responders among patients with stable angina pectoris scheduled for elective coronary stent placement. Thromb Haemost 2003; 89: 783-787.
    • (2003) Thromb Haemost , vol.89 , pp. 783-787
    • Muller, I.1    Besta, F.2    Schulz, C.3    Massberg, S.4    Schonig, A.5    Gawaz, M.6
  • 20
    • 18144371221 scopus 로고    scopus 로고
    • The relation of dosing to clopidogrel responsiveness and the incidence of high post-treatment platelet aggregation in patients undergoing coronary stenting
    • Gurbel PA, Bliden KP, Hayes KM, Yoho JA, Herzog WR, Tantry US. The relation of dosing to clopidogrel responsiveness and the incidence of high post-treatment platelet aggregation in patients undergoing coronary stenting. J Am Coll Cardiol 2005; 45: 1392-1396.
    • (2005) J Am Coll Cardiol , vol.45 , pp. 1392-1396
    • Gurbel, P.A.1    Bliden, K.P.2    Hayes, K.M.3    Yoho, J.A.4    Herzog, W.R.5    Tantry, U.S.6
  • 23
    • 0034792584 scopus 로고    scopus 로고
    • Clinical relevance of genetic polymorphisms in the human CYP2C subfamily
    • Goldstein JA. Clinical relevance of genetic polymorphisms in the human CYP2C subfamily. Br J Clin Pharmacol 2001; 52: 349-355.
    • (2001) Br J Clin Pharmacol , vol.52 , pp. 349-355
    • Goldstein, J.A.1
  • 24
    • 0029028932 scopus 로고
    • Geographical/interracial differences in polymorphic drug oxidation. Current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19
    • Bertilsson L. Geographical/interracial differences in polymorphic drug oxidation. Current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19. Clin Pharmacokinet 1995; 29: 192-209.
    • (1995) Clin Pharmacokinet , vol.29 , pp. 192-209
    • Bertilsson, L.1
  • 25
    • 67650901939 scopus 로고    scopus 로고
    • Factors influencing clopidogrel efficacy in patients with stable coronary artery disease undergoing elective percutaneous coronary intervention: Statin's advantage and the smoking ''paradox
    • Motovska Z, Widimsky P, Petr R, Bilkova D, Marinov I, Simek S, et al. Factors influencing clopidogrel efficacy in patients with stable coronary artery disease undergoing elective percutaneous coronary intervention: statin's advantage and the smoking ''paradox''. J Cardiovasc Pharmacol 2009; 53: 368-372.
    • (2009) J Cardiovasc Pharmacol , vol.53 , pp. 368-372
    • Motovska, Z.1    Widimsky, P.2    Petr, R.3    Bilkova, D.4    Marinov, I.5    Simek, S.6
  • 26
    • 65449170730 scopus 로고    scopus 로고
    • Predictors of heightened platelet reactivity despite dual-antiplatelet therapy in patients undergoing percutaneous coronary intervention
    • Price MJ, Nayak KR, Barker CM, Kandzari DE, Teirstein PS. Predictors of heightened platelet reactivity despite dual-antiplatelet therapy in patients undergoing percutaneous coronary intervention. Am J Cardiol 2009; 103: 1339-1343.
    • (2009) Am J Cardiol , vol.103 , pp. 1339-1343
    • Price, M.J.1    Nayak, K.R.2    Barker, C.M.3    Kandzari, D.E.4    Teirstein, P.S.5
  • 27
    • 0033530251 scopus 로고    scopus 로고
    • Smoking in China: Findings of the 1996 National Prevalence Survey
    • Yang G, Fan L, Tan J, Qi G, Zhang Y, Samet JM, et al. Smoking in China: findings of the 1996 National Prevalence Survey. JAMA 1999; 282: 1247-1253.
    • (1999) JAMA , vol.282 , pp. 1247-1253
    • Yang, G.1    Fan, L.2    Tan, J.3    Qi, G.4    Zhang, Y.5    Samet, J.M.6
  • 28
    • 7244239220 scopus 로고    scopus 로고
    • Cigarette smoking and exposure to environmental tobacco smoke in China: The international collaborative study of cardiovascular disease in Asia
    • Gu D, Wu X, Reynolds K, Duan X, Xin X, Reynolds RF, et al. Cigarette smoking and exposure to environmental tobacco smoke in China: the international collaborative study of cardiovascular disease in Asia. Am J Public Health 2004; 94: 1972-1976.
    • (2004) Am J Public Health , vol.94 , pp. 1972-1976
    • Gu, D.1    Wu, X.2    Reynolds, K.3    Duan, X.4    Xin, X.5    Reynolds, R.F.6
  • 29
    • 67649645191 scopus 로고    scopus 로고
    • Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with coronary artery disease
    • Varenhorst C, James S, Erlinge D, Brandt JT, Braun OO, Man M, et al. Genetic variation of CYP2C19 affects both pharmacokinetic and pharmacodynamic responses to clopidogrel but not prasugrel in aspirin-treated patients with coronary artery disease. Eur Heart J 2009; 30: 1744-1752.
    • (2009) Eur Heart J , vol.30 , pp. 1744-1752
    • Varenhorst, C.1    James, S.2    Erlinge, D.3    Brandt, J.T.4    Braun, O.O.5    Man, M.6
  • 31
    • 38349065084 scopus 로고    scopus 로고
    • Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: The randomized double-blind OCLA (Omeprazole CLopidogrel Aspirin) study
    • Gilard M, Arnaud B, Cornily JC, Le Gal G, Lacut K, Le Calvez G, et al. Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: the randomized double-blind OCLA (Omeprazole CLopidogrel Aspirin) study. J Am Coll Cardiol 2008; 51: 256-260.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 256-260
    • Gilard, M.1    Arnaud, B.2    Cornily, J.C.3    le Gal, G.4    Lacut, K.5    le Calvez, G.6
  • 32
    • 62649164844 scopus 로고    scopus 로고
    • A population-based study of the drug interaction between proton pump inhibitors and clopidogrel
    • Juurlink DN, Gomes T, Ko DT, Szmitko PE, Austin PC, Tu JV, et al. A population-based study of the drug interaction between proton pump inhibitors and clopidogrel. CMAJ 2009; 180: 713-718.
    • (2009) CMAJ , vol.180 , pp. 713-718
    • Juurlink, D.N.1    Gomes, T.2    Ko, D.T.3    Szmitko, P.E.4    Austin, P.C.5    Tu, J.V.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.