3-Benzylamino-β-carboline derivatives induce apoptosis through G 2/M arrest in human carcinoma cells HeLa S-3

European Journal of Medicinal Chemistry

Volumn 46, Issue 2, 2011, Pages 636-646

  Ikeda, Reiko ^a   Iwaki, Toshie ^a   Iida, Tomoko ^a   Okabayashi, Takasumi ^a   Nishi, Eishiro ^a   Kurosawa, Masaki ^a   Sakai, Norio ^a   Konakahara, Takeo ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

Carboline; Anti tumor activity; Apoptosis; Chromatin condensation; DNA ladder; G 2 M cell cycle arrest

Indexed keywords

(BETA CARBOLIN 3 YL)CYCLOHEXANECARBOXAMIDE; (BETA CARBOLIN 3 YL)ISOBUTANECARBOXAMIDE; 2 METHYL 3 BENZYLAMINO BETA CARBOLINIUM; 2 METHYL 3 BENZYLAMINO BETA CARBOLINIUM ACETATE; 2 METHYL 3 BENZYLAMINO BETA CARBOLINIUM CHLORIDE; 3 (2 PHENYLETHYL)AMINO BETA CARBOLINE; 3 (2,2 DIMETHYLPROPYL)AMINO BETA CARBOLINE; 3 (3 PHENYLPROPYL)AMINO BETA CARBOLINE; 3 [3 [2 (N TERT BUTOXYCARBONYL)AMINO]ETHOXYBENZYL]AMINO BETA CARBOLINE; 3 [4 [2 (N TERT BUTOXYCARBONYL)AMINO]ETHOXYBENZYL]AMINO BETA CARBOLINE; 3 BENZYLAMINO BETA CARBOLINE; 3 BENZYLAMINO BETA CARBOLINE DERIVATIVE; 3 CYCLOHEXYLMETHYLAMINO BETA CARBOLINE; 3 ETHYLAMINO BETA CARBOLINE; 3 HYDROXY 3 BENZYLAMINO B CARBOLINE; 3 ISOBUTYLAMINO BETA CARBOLINE; 3 METHOXYCARBONYL 3 BENZYLAMINO BETA CARBOLINE; 3 METHYLAMINO BETA CARBOLINE; 4 METHOXYCARBONYL 3 BENZYLAMINO BETA CARBOLINE; ANION; ANTINEOPLASTIC AGENT; BETA CARBOLINE; CARBOLINE DERIVATIVE; HYDROXYL GROUP; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL VIABILITY; DNA FRAGMENTATION; DRUG STRUCTURE; FEMALE; FLOW CYTOMETRY; HELA CELL; HUMAN; HUMAN CELL; IC 50; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CARBOLINES; CELL DIVISION; DRUG SCREENING ASSAYS, ANTITUMOR; G2 PHASE; HELA CELLS; HUMANS; MOLECULAR STRUCTURE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79151483925     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.11.044     Document Type: Article

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