The irreversibility of platelet aggregation is regulated by myosin IIA, but is not compromised in MYH9-related disease

Thrombosis Research

Volumn 127, Issue 2, 2011, Pages 171-173

  Catricalà, Silvia ^a   Guidetti, Gianni F ^a   Canobbio, Ilaria ^a   Pecci, Alessandro ^a   Balduini, Carlo L ^a   Balduini, Cesare ^a   Torti, Mauro ^a  

^a UNIVERSITY OF PAVIA   (Italy)

Author keywords

MYH9 RD; MYH9 related disease

Indexed keywords

ACTIN; ADENOSINE TRIPHOSPHATASE; MYOSIN HEAVY CHAIN; MYOSIN IIA; PROTEIN MYH9; UNCLASSIFIED DRUG;

GENE MUTATION; GENERAL ASPECTS OF DISEASE; HUMAN; LETTER; PRIORITY JOURNAL; PROTEIN INTERACTION; THROMBOCYTE AGGREGATION; THROMBOCYTOPENIA;

HUMANS; MOLECULAR MOTOR PROTEINS; MYOSIN HEAVY CHAINS; NONMUSCLE MYOSIN TYPE IIA; PLATELET AGGREGATION; THROMBOCYTOPENIA;

EID: 79151482103     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2010.08.004     Document Type: Letter

References (10)

1. K. Althaus, and A. Greinacher MYH9-related platelet disorders Semin Thromb Hemost 35 2009 189 203
2. A. Pecci, I. Canobbio, A. Balduini, L. Stefanini, B. Cisterna, C. Marseglia, P. Noris, A. Savoia, C.L. Balduini, and M. Torti Pathogenetic mechanisms of hematological abnormalities of patients with MYH9 mutations Hum Mol Genet 14 2005 3169 3178
3. I. Canobbio, P. Noris, A. Pecci, A. Balduini, C.L. Balduini, and M. Torti Altered cytoskeleton organization in platelets from patients with MYH9-related disease J Thromb Haemost 3 2005 1026 1035
4. J.E. Fox Cytoskeletal proteins and platelet signaling Thromb Haemost 86 2001 198 213
5. S.D. Calaminus, J.M. Auger, O.J. McCarty, M.J. Wakelam, L.M. Machesky, and S.P. Watson Myosin IIa contractility is required for maintenance of platelet structure during spreading on collagen and contributes to thrombus stability J Thromb Haemost 5 2007 2136 2145
6. G.J. Johnson, L.A. Leis, M.D. Krumwiede, and J.G. White The critical role of myosin IIA in platelet internal contraction J Thromb Haemost 5 2007 1516 1529
7. C. Léon, A. Eckly, B. Hechler, B. Aleil, M. Freund, C. Ravanat, M. Jourdain, C. Nonne, J. Weber, R. Tiedt, M.P. Gratacap, S. Severin, J.P. Cazenave, F. Lanza, R. Skoda, and C. Gachet Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion Blood 110 2007 3183 3191
8. A. Ono, E. Westein, S. Hsiao, W.S. Nesbitt, J.R. Hamilton, S.M. Schoenwaelder, and S.P. Jackson Identification of a fibrin-independent platelet contractile mechanism regulating primary hemostasis and thrombus growth Blood 112 2008 90 99
9. E.I. Peerschke, and J.A. Wainer Examination of irreversible platelet-fibrinogen interactions Am J Physiol 248 1985 C466 C472
10. M. Torti, E.T. Festetics, A. Bertoni, F. Sinigaglia, and C. Balduini Agonist-induced actin polymerization is required for the irreversibility of platelet aggregation Thromb Haemost 76 1996 444 449