Anticancer properties of 10-hydroxycamptothecin in a murine melanoma pulmonary metastasis model in vitro and in vivo

Toxicology in Vitro

Volumn 25, Issue 2, 2011, Pages 513-520

  Hu, Wei ^a   Zhang, Chao ^b   Fang, Yun ^a   Lou, Chenghua ^c  

^a THE AFFILIATED DRUM TOWER HOSPITAL OF NANJING UNIVERSITY MEDICAL SCHOOL   (China)

^b NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^c Nanjing Haichang Chinese Herbal Medicinal Pieces Co Ltd   (China)

Author keywords

Aerosol; Apoptosis; HCPT; Melanoma lung metastasis

Indexed keywords

10 HYDROXYCAMPTOTHECIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE S PHASE; CELL GROWTH; CELL STRUCTURE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; IN VITRO STUDY; IN VIVO STUDY; LUNG METASTASIS; MELANOMA; MELANOMA CELL; MOUSE; NONHUMAN;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CAMPTOTHECIN; CELL CYCLE; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; FEMALE; LUNG NEOPLASMS; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL;

MURINAE;

EID: 79151476843     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2010.11.009     Document Type: Article

References (35)

1. Brown T.J., Nelson B.R. Melanoma: a clinical review. Cutis 1999, 63:275-278. 281-284.
2. Chen C.N., Wu C.L., Lin J.K. Propolin C from propolis induces apoptosis through activating caspases, Bid and cytochrome c release in human melanoma cells. Biochemical Pharmacology 2004, 67:53-66.
3. Chen J., Fang Y., Zhang H.X., Huang L.L., Qian X.P., Liu B.R. Distribution of hydroxycamptothecin after aerosol inhalation in rabbits. Acta Pharmaceutica Sinica 2004, 39(9):747-751.
4. Chen C.N., Wu C.L., Lin J.K. Apoptosis of human melanoma cells induced by the novel compounds propolin A and propolin B from Taiwenese propolis. Cancer Letters 2007, 245:218-231.
5. Debatin K.M., Krammer P.H. Death receptors in chemotherapy and cancer. Oncogene 2004, 23:2950-2966.
6. Du J.H., Zhang H.D., Ma Z.J., Ji K.M. Artesunate induces oncosis-like cell death in vitro and has antitumor activity against pancreatic cancer xenografts in vivo. Cancer Chemotherapy and Pharmacology 2010, 65:895-902.
7. Fan H.T., Li Z., Zhu D.C., Liu L.C., Zheng H.S., Liu X.F. Inhibition of proliferation, anti-invasion and induction of apoptosis in bladder cancer cells by 10-HCPT. Life Science Research 2005, 9(1):90-93.
8. Fidler I.J. Metastasis: guantitative analysis of distribution and fate of tumor embolilabeled with 125I-5-iodo-2'-deoxyuridine. Journal of the National Cancer Institute 1970, 45(4):773-782.
9. Franke J.C., Plötz M., Prokop A., Geilen C.C., Schmalz H.G., Eberle J. New caspase-independent but ROS-dependent apoptosis pathways are targeted in melanoma cells by an iron-containing cytosine analogue. Biochemical Pharmacology 2010, 79:575-586.
10. Fu Y.R., Yi Z.J., Yan Y.R., Qiu Z.Y. Hydroxycamptothecin-induced apoptosis in hepatoma SMMC-7721 cells and the role of mitochondrial pathway. Mitochondrion 2006, 6:211-217.
11. Guimarães F.S.F., Andrade L.F., Martins S.T., Abud A.P., Sene R.V., Wanderer C., Tiscornia I., Bollati-Fogolín M., Bichi D.F., Trindade E.S. In vitro and in vivo anticancer properties of a Calcarea carbonica derivative complex (M8) treatment in a murine melanoma model. BMC Cancer 2010, 10:113-126.
12. Hengartner M.O. The biochemistry of apoptosis. Nature 2000, 407:770-776.
13. Howe H.L., Wingo P.A., Thun M.J., Ries L.A., Rosenberg H.M., Feigal E.G., Edwards B.K. Annual report to the nation on the status of cancer (1973 through 1998), featuring cancers with recent increasing trends. Journal of the National Cancer Institute 2001, 93:824-842.
14. Hsiang Y.H., Hertzberg R., Hecht S., Liu L.F. Camptothecin induces proteinlinked DNA breaks via mammalian DNA topoisomerase-I. Journal of Biological Chemistry 1985, 260:14873-14878.
15. Jun H.S., Park T., Lee C.K., Kang M.K., Park M.S., Kang H.I., Surh Y.J., Kim O.H. Capsaicin induced apoptosis of B16-F10 melanoma cells through down-regulation of Bcl-2. Food and Chemical Toxicology 2007, 45:708-715.
16. Knight V., Koshkina N.V., Golunski E., Roberts L.E., Gilbert B.E. Cyclosporin a aerosol improves the anticancer effect of paclitaxel aerosol in mice. Transaction of the American Clinical and Climatological Association 2004, 115:395-404.
17. Koshkina N.V., Kleinerman E.S., Waldrep C., Jia S.F., Worth L.L., Gilbert B.E., Knight V. 9-Nitrocamptothecin liposome aerosol treatment of melanoma and osteosarcoma lung metastases in mice. Clinical Cancer Research 2000, 6:2876-2880.
18. Koshkina N.V., Waldrep J.C., Roberts L.E., Golunski E., Melton S., Knight V. Paclitaxel liposome aerosol treatment induces inhibition of pulmonary metastases in murine renal carcinoma model. Clinical Cancer Research 2001, 7:3258-3262.
19. Li W.B., Feng J., Geng S.M., Zhang P.Y., Yan X.N., Hu G., Zhang C.Q., Shi B.J. Induction of apoptosis by Hax-1 siRNA in melanoma cells. Cell Biology International 2009, 33:548-554.
20. Locatelli C., Leal P.C., Yunes R.A., Nunes R.J., Creczynski-Pasa T.B. Gallic acid ester derivatives induce apoptosis and cell adhesion inhibition in melanoma cells: the relationship between free radical generation, glutathione depletion and cell death. Chemico-Biological Interactions 2009, 181:175-184.
21. Lou C.H., Wang M.Y., Yang G.M., Cai H., Li Y., Zhao F.M., Yang H., Tong L., Cai B.C. Preliminary studies on anti-tumor activity of 20, 40-dihydroxychalcone isolated from Herba Oxytropis in human gastric cancer MGC-803 cells. Toxicology in Vitro 2009, 23:906-910.
22. Luo Z.F., Zhou Y., Liu M.Y. Effects of hydroxycamptothecin and teniposide on proliferation and apoptosis of gastric cancer cell line BGC-823. Chinese Journal of Cancer 2007, 26(8):843-845.
23. Sakon S., Xue X., Takekawa M., Sasazuki T., Okazaki T., Kojima Y., Piao J.H., Yagita H., Okumura K., Doi T., Nakano H. NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death. The EMBO Journal 2003, 22:3898-3909.
24. Shen H.B., Zeng Y.K., Gu Z.Q., Zhang L., Kang J., Pan J., Zhou B., Qi J. Hydroxycamptothecin induced apoptosis in 5637 cells line: an in-vitro model for high-risk superficial bladder cancer. Journa1 of Clinical Urology 2009, 24(4):306-310.
25. Tu S.P., Jiang S.H., Tan J.H., Zhong J., Qiao M.M., Jiang X.H., Zhang Y.P., Yuan Y.Z., Wu Y.L., Wu Y.X. The mechanisms of apoptosis induced by hydroxycamptothecin in gastric cancer cells. Chinese Journal of Digestion 2001, 21(5):274-277.
26. Wall M.E., Wani M.C., Cook C.E. Plant antitumor agent. 1. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor from camptotheca acumianta. American Chemical Society 1966, 88:3888-3890.
27. Wang Y., Liu C.Y., Guo Y.Z., Wang Z., Jin H., Li S.L., Cai S., Cai Y.W. Effect of hydroxycamptothecin on proliferation on human lung cancer cell line A549. Chinese Journa1 of Information on TCM 2007, 14(11):35-36.
28. Widlak P., Li L.Y., Wang X., Garrard W.T. Action of recombinant human apoptotic endonuclease G on naked DNA and chromatin substrates: cooperation with exonuclease and DNase I. Journal of Biological Chemistry 2001, 276:48404-48409.
29. Wu Y., Zeng F.Q., Wang Y.B., Wang L. Hydroxycamptothecin promotes the apoptosis of prostate cancer cell line PC-3. National Journal of Andrology 2007, 13(10):890-894.
30. Ye C.L., Liu J.W., Wei D.Z., Lu Y.H., Qian F. In vitro anti-tumor activity of 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone against six established human cancer cell lines. Pharmacological Research 2004, 50:505-510.
31. Youn M.J., Kim J.K., Park S.y., Kim Y., Park C., Kim E.S., Park E.I., So H.S., Park R. Potential anticancer properties of the water extract of Inontus obliquus by induction of apoptosis in melanoma B16-F10 cells. Journal of Ethnopharmacology 2009, 121:221-228.
32. Zhang X.W., Jiang J.F., Xu B. Differentiation-inducing action of 10-hydroxycamptothecin on human hepatoma HepG2 cells. Acta Phammcologica Sinica 2000, 21(4):364-368.
33. Zhang L., Li S., Liao H., Jiang W.Q., Guan Z.Z. Phase I trial of pharmacokinetics and human tolerability to 10 hydroxycamptothecin in patients with advanced malignancy. Chinese Journal of Cancer 2001, 20(12):1391-1395.
34. Zhang S.S., Fang Y., Hu W. Determination of two forms of hydroxycamptothecin concentration in hepat-tumor tissues by HPLC-FLD. Research and Practice of Chinese Medicines 2009, 23(1):48-51.
35. Zhang Y.C., Zhou Y., Yang M., Fan D.M., Xiong D.S., Yang C.Z. Establishment of a pulmonary metastasis model of human melanoma in nude mice. Acta Laboratorium Animalis Scientia Sinica 2009, 17(1):1-4.