Targeted induction of antigen expression within dendritic cells modulates antigen-specific immunity afforded by recombinant BCG

Vaccine

Volumn 29, Issue 7, 2011, Pages 1374-1381

  Kong, Carlyn U ^a   Ng, Lai Guan ^a,b,c   Nambiar, Jonathan K ^a   Spratt, Joanne M ^a   Weninger, Wolfgang ^a,b   Triccas, James A ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b University of Sydney   (Australia)

^c AGENCY FOR SCIENCE   (Singapore)

Author keywords

Antigen expression; BCG; Dendritic cell; Vaccine

Indexed keywords

BCG VACCINE; GAMMA INTERFERON; GREEN FLUORESCENT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ANTIGEN SPECIFICITY; ARTICLE; CD4+ T LYMPHOCYTE; CELLULAR IMMUNITY; DENDRITIC CELL; DRUG EFFICACY; GENE EXPRESSION; IMMUNE RESPONSE; LYMPHOCYTE PROLIFERATION; MOUSE; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; TUBERCULOSIS; VACCINATION;

ACYLTRANSFERASES; ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BCG VACCINE; CD4-POSITIVE T-LYMPHOCYTES; DENDRITIC CELLS; IMMUNITY, CELLULAR; INTERFERON-GAMMA; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PROMOTER REGIONS, GENETIC; RECOMBINANT PROTEINS; TUBERCULOSIS;

EID: 79151469649     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2010.12.070     Document Type: Article

References (30)

1. Nchinda G., Kuroiwa J., Oks M., Trumpfheller C., Park C.G., Huang Y., et al. The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells. J Clin Invest 2008 Apr, 118(4):1427-1436.
2. Ryan A.A., Wozniak T.M., Shklovskaya E., O'Donnell M.A., Fazekas de St Groth B., Britton W.J., et al. Improved protection against disseminated tuberculosis by Mycobacterium bovis bacillus Calmette-Guérin secreting murine GM-CSF is associated with expansion and activation of APCs. J Immunol 2007, 179(December (12)):8418-8424.
3. Lozza L., Rivino L., Guarda G., Jarrossay D., Rinaldi A., Bertoni F., et al. The strength of T cell stimulation determines IL-7 responsiveness, secondary expansion, and lineage commitment of primed human CD4(+)IL-7R(hi) T cells. Eur J Immunol 2008, 38(January (1)):30-39.
4. Ohara N., Yamada T. Recombinant BCG vaccines. Vaccine 2001, 19(30):4089-4098.
5. Alexandroff A.B., Jackson A.M., O'Donnell M.A., James K. BCG immunotherapy of bladder cancer: 20 years on. Lancet 1999, 353(9165):1689-1694.
6. Ristori G., Buzzi M.G., Sabatini U., Giugni E., Bastianello S., Viselli F., et al. Use of Bacille Calmette-Guerin (BCG) in multiple sclerosis. Neurology 1999, 53(October (7)):1588-1589.
7. Kodama S., Davis M., Faustman D.L. The therapeutic potential of tumor necrosis factor for autoimmune disease: a mechanistically based hypothesis. Cell Mol Life Sci 2005, 62(August (16)):1850-1862.
8. Jiao X., Lo-Man R., Guermonprez P., Fiette L., Deriaud E., Burgaud S., et al. Dendritic cells are host cells for mycobacteria in vivo that trigger innate and acquired immunity. J Immunol 2002, 168(February (3)):1294-1301.
9. Wolf A.J., Linas B., Trevejo-Nunez G.J., Kincaid E., Tamura T., Takatsu K., et al. Mycobacterium tuberculosis infects dendritic cells with high frequency and impairs their function in vivo. J Immunol 2007, 179(August (4)):2509-2519.
10. Chang Z., Primm T.P., Jakana J., Lee I.H., Serysheva I., Chiu W., et al. Mycobacterium tuberculosis 16-kDa antigen (Hsp16.3) functions as an oligomeric structure in vitro to suppress thermal aggregation. J Biol Chem 1996, 271(12):7218-7223.
11. Yuan Y., Crane D.D., Barry C.E. Stationary phase-associated protein expression in Mycobacterium tuberculosis: function of the mycobacterial alpha-crystallin homolog. J Bacteriol 1996, 178(15):4484-4492.
12. Yuan Y., Crane D.D., Simpson R.M., Zhu Y.Q., Hickey M.J., Sherman D.R., et al. The 16-kDa alpha-crystallin (Acr) protein of Mycobacterium tuberculosis Is required for growth in macrophages. Proc Natl Acad Sci USA 1998, 95(16):9578-9583.
13. Garbe T.R., Hibler N.S., Deretic V. Response to reactive nitrogen intermediates in Mycobacterium tuberculosis: induction of the 16-kilodalton alpha-crystallin homolog by exposure to nitric oxide donors. Infect Immun 1999, 67(1):460-465.
14. Shi L., Jung Y.J., Tyagi S., Gennaro M.L., North R.J. Expression of Th1-mediated immunity in mouse lungs induces a Mycobacterium tuberculosis transcription pattern characteristic of non-replicating persistence. Proc Natl Acad Sci USA 2003, 100(1):241-246.
15. Tamura T., Ariga H., Kinashi T., Uehara S., Kikuchi T., Nakada M., et al. The role of antigenic peptide in CD4+ T helper phenotype development in a T cell receptor transgenic model. Int Immunol 2004, 16(December (12)):1691-1699.
16. Stover C.K., de la Cruz V.F., Fuerst T.R., Burlein J.E., Benson L.A., Bennett L.T., et al. New use of BCG for recombinant vaccines. Nature 1991, 351(6326):456-460.
17. Palendira U., Spratt J.M., Britton W.J., Triccas J.A. Expanding the antigenic repertoire of BCG improves protective efficacy against aerosol Mycobacterium tuberculosis infection. Vaccine 2005, 23(February (14)):1680-1685.
18. Demangel C., Bean A.G., Martin E., Feng C.G., Kamath A.T., Britton W.J. Protection against aerosol Mycobacterium tuberculosis infection using Mycobacterium bovis Bacillus Calmette Guérin-infected dendritic cells. Eur J Immunol 1999, 29(6):1972-1979.
19. Triccas J.A., Sun L., Palendira U., Britton W.J. Comparative affects of plasmid-encoded interleukin 12 and interleukin 18 on the protective efficacy of DNA vaccination against Mycobacterium tuberculosis. Immunol Cell Biol 2002 Aug, 80(4):346-350.
20. Triccas J.A. Recombinant BCG as a vaccine vehicle to protect against tuberculosis. Bioeng Bugs 2001, 1(2):1-6.
21. Yuan Y., Crane D.D., Simpson R.M., Zhu Y.Q., Hickey M.J., Sherman D.R., et al. The 16-kDa alpha-crystallin (Acr) protein of Mycobacterium tuberculosis is required for growth in macrophages. Proc Natl Acad Sci USA 1998, 95(16):9578-9583.
22. Hickman S.P., Chan J., Salgame P. Mycobacterium tuberculosis induces differential cytokine production from dendritic cells and macrophages with divergent effects on naive T cell polarization. J Immunol 2002, 168(May (9)):4636-4642.
23. Giacomini E., Iona E., Ferroni L., Miettinen M., Fattorini L., Orefici G., et al. Infection of human macrophages and dendritic cells with Mycobacterium tuberculosis induces a differential cytokine gene expression that modulates T cell response. J Immunol 2001, 166(June (12)):7033-7041.
24. Dietrich J., Lundberg C.V., Andersen P. TB vaccine strategies-what is needed to solve a complex problem?. Tuberculosis (Edinb) 2006, 86(May-July (3-4)):163-168.
25. Horwitz M.A., Harth G., Dillon B.J., Maslesa-Galic S. Recombinant Bacillus Calmette-Guérin (BCG) vaccines expressing the Mycobacterium tuberculosis 30-kDa major secretory protein induce greater protective immunity against tuberculosis than conventional BCG vaccines in a highly susceptible animal model. Proc Natl Acad Sci USA 2000, 97(December (25)):13853-13858.
26. Al-Zarouni M., Dale J.W. Expression of foreign genes in Mycobacterium bovis BCG strains using different promoters reveals instability of the hsp60 promoter for expression of foreign genes in Mycobacterium bovis BCG strains. Tuberculosis (Edinb) 2002, 82(6):283-291.
27. Jagannath C., Lindsey D.R., Dhandayuthapani S., Xu Y., Hunter R.L., Eissa N.T. Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells. Nat Med 2009, 15(March (3)):267-276.
28. Hohmann E.L., Oletta C.A., Loomis W.P., Miller S.I. Macrophage-inducible expression of a model antigen in Salmonella typhimurium enhances immunogenicity. Proc Natl Acad Sci U S A 1995, 92(March (7)):2904-2908.
29. Dunstan S.J., Simmons C.P., Strugnell R.A. Use of in vivo-regulated promoters to deliver antigens from attenuated Salmonella enterica var Typhimurium. Infect Immun 1999, 67(October (10)):5133-5141.
30. Londono L.P., Chatfield S., Tindle R.W., Herd K., Gao X.M., Frazer I., et al. Immunisation of mice using Salmonella typhimurium expressing human papillomavirus type 16 E7 epitopes inserted into hepatitis B virus core antigen. Vaccine 1996, 14(April (6)):545-552.