-
1
-
-
10744233716
-
Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia
-
10.1056/NEJMoa022457 12637609
-
SG O'Brien F Guilhot RA Larson I Gathmann M Baccarani F Cervantes JJ Cornelissen T Fischer A Hochhaus T Hughes K Lechner JL Nielsen P Rousselot J Reiffers G Saglio J Shepherd B Simonsson A Gratwohl JM Goldman H Kantarjian K Taylor G Verhoef AE Bolton R Capdeville BJ Druker 2003 Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia N Engl J Med 348 994 1004 10.1056/NEJMoa022457 12637609
-
(2003)
N Engl J Med
, vol.348
, pp. 994-1004
-
-
O'Brien, S.G.1
Guilhot, F.2
Larson, R.A.3
Gathmann, I.4
Baccarani, M.5
Cervantes, F.6
Cornelissen, J.J.7
Fischer, T.8
Hochhaus, A.9
Hughes, T.10
Lechner, K.11
Nielsen, J.L.12
Rousselot, P.13
Reiffers, J.14
Saglio, G.15
Shepherd, J.16
Simonsson, B.17
Gratwohl, A.18
Goldman, J.M.19
Kantarjian, H.20
Taylor, K.21
Verhoef, G.22
Bolton, A.E.23
Capdeville, R.24
Druker, B.J.25
more..
-
2
-
-
67349233062
-
Six-year follow-up of patients receiving imatinib for the first-line treatment of chronic myeloid leukemia
-
1:CAS:528:DC%2BD1MXntFygt7w%3D 10.1038/leu.2009.38 19282833
-
A Hochhaus SG O'Brien F Guilhot BJ Druker S Branford L Foroni JM Goldman MC Muller JP Radich M Rudoltz M Mone I Gathmann TP Hughes RA Larson IRIS Investigators 2009 Six-year follow-up of patients receiving imatinib for the first-line treatment of chronic myeloid leukemia Leukemia 23 1054 1061 1:CAS:528:DC%2BD1MXntFygt7w%3D 10.1038/leu.2009.38 19282833
-
(2009)
Leukemia
, vol.23
, pp. 1054-1061
-
-
Hochhaus, A.1
O'Brien, S.G.2
Guilhot, F.3
Druker, B.J.4
Branford, S.5
Foroni, L.6
Goldman, J.M.7
Muller, M.C.8
Radich, J.P.9
Rudoltz, M.10
Mone, M.11
Gathmann, I.12
Hughes, T.P.13
Larson, R.A.14
Iris, I.15
-
3
-
-
33845444046
-
Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia
-
1:CAS:528:DC%2BD28Xht12ntrzM 10.1056/NEJMoa062867 17151364
-
BJ Druker F Guilhot SG O'Brien I Gathmann H Kantarjian N Gattermann MW Deininger RT Silver JM Goldman RM Stone F Cervantes A Hochhaus BL Powell JL Gabrilove P Rousselot J Reiffers JJ Cornelissen T Hughes H Agis T Fischer G Verhoef J Shepherd G Saglio A Gratwohl JL Nielsen JP Radich B Simonsson K Taylor M Baccarani C So L Letvak RA Larson IRIS Investigators 2006 Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia N Engl J Med 355 2408 2417 1:CAS:528:DC%2BD28Xht12ntrzM 10.1056/NEJMoa062867 17151364
-
(2006)
N Engl J Med
, vol.355
, pp. 2408-2417
-
-
Druker, B.J.1
Guilhot, F.2
O'Brien, S.G.3
Gathmann, I.4
Kantarjian, H.5
Gattermann, N.6
Deininger, M.W.7
Silver, R.T.8
Goldman, J.M.9
Stone, R.M.10
Cervantes, F.11
Hochhaus, A.12
Powell, B.L.13
Gabrilove, J.L.14
Rousselot, P.15
Reiffers, J.16
Cornelissen, J.J.17
Hughes, T.18
Agis, H.19
Fischer, T.20
Verhoef, G.21
Shepherd, J.22
Saglio, G.23
Gratwohl, A.24
Nielsen, J.L.25
Radich, J.P.26
Simonsson, B.27
Taylor, K.28
Baccarani, M.29
So, C.30
Letvak, L.31
Larson, R.A.32
Iris, I.33
more..
-
4
-
-
0142121411
-
Imatinib mesylate (STI-571 Glivec, Gleevec) is an active agent for gastrointestinal stromal tumours, but does not yield responses in other soft-tissue sarcomas that are unselected for a molecular target. Results from an EORTC Soft Tissue and Bone Sarcoma Group phase II study
-
1:CAS:528:DC%2BD3sXmvVKgtrc%3D 10.1016/S0959-8049(02)00836-5 12957454
-
J Verweij A van Oosterom JY Blay I Judson S Rodenhuis W van der Graaf J Radford A Le Cesne PC Hogendoorn ED di Paola M Brown OS Nielsen 2003 Imatinib mesylate (STI-571 Glivec, Gleevec) is an active agent for gastrointestinal stromal tumours, but does not yield responses in other soft-tissue sarcomas that are unselected for a molecular target. Results from an EORTC Soft Tissue and Bone Sarcoma Group phase II study Eur J Cancer 39 2006 2011 1:CAS:528: DC%2BD3sXmvVKgtrc%3D 10.1016/S0959-8049(02)00836-5 12957454
-
(2003)
Eur J Cancer
, vol.39
, pp. 2006-2011
-
-
Verweij, J.1
Van Oosterom, A.2
Blay, J.Y.3
Judson, I.4
Rodenhuis, S.5
Van Der Graaf, W.6
Radford, J.7
Le Cesne, A.8
Hogendoorn, P.C.9
Di Paola, E.D.10
Brown, M.11
Nielsen, O.S.12
-
5
-
-
0037103424
-
Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
-
1:CAS:528:DC%2BD38XmtV2nt7s%3D 10.1056/NEJMoa020461 12181401
-
GD Demetri M von Mehren CD Blanke AD Van den Abbeele B Eisenberg PJ Roberts MC Heinrich DA Tuveson S Singer M Janicek JA Fletcher SG Silverman SL Silberman R Capdeville B Kiese B Peng S Dimitrijevic BJ Druker C Corless CD Fletcher H Joensuu 2002 Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors N Engl J Med 347 472 480 1:CAS:528: DC%2BD38XmtV2nt7s%3D 10.1056/NEJMoa020461 12181401
-
(2002)
N Engl J Med
, vol.347
, pp. 472-480
-
-
Demetri, G.D.1
Von Mehren, M.2
Blanke, C.D.3
Van Den Abbeele, A.D.4
Eisenberg, B.5
Roberts, P.J.6
Heinrich, M.C.7
Tuveson, D.A.8
Singer, S.9
Janicek, M.10
Fletcher, J.A.11
Silverman, S.G.12
Silberman, S.L.13
Capdeville, R.14
Kiese, B.15
Peng, B.16
Dimitrijevic, S.17
Druker, B.J.18
Corless, C.19
Fletcher, C.D.20
Joensuu, H.21
more..
-
6
-
-
39149123549
-
Long-term results from a randomized phase II trial of standard- versus higher-dose imatinib mesylate for patients with unresectable or metastatic gastrointestinal stromal tumors expressing KIT
-
1:CAS:528:DC%2BD1cXis1alsL0%3D 10.1200/JCO.2007.13.4403 18235121
-
CD Blanke GD Demetri M von Mehren MC Heinrich B Eisenberg JA Fletcher CL Corless CD Fletcher PJ Roberts D Heinz E Wehre Z Nikolova H Joensuu 2008 Long-term results from a randomized phase II trial of standard- versus higher-dose imatinib mesylate for patients with unresectable or metastatic gastrointestinal stromal tumors expressing KIT J Clin Oncol 26 620 625 1:CAS:528:DC%2BD1cXis1alsL0%3D 10.1200/JCO.2007.13.4403 18235121
-
(2008)
J Clin Oncol
, vol.26
, pp. 620-625
-
-
Blanke, C.D.1
Demetri, G.D.2
Von Mehren, M.3
Heinrich, M.C.4
Eisenberg, B.5
Fletcher, J.A.6
Corless, C.L.7
Fletcher, C.D.8
Roberts, P.J.9
Heinz, D.10
Wehre, E.11
Nikolova, Z.12
Joensuu, H.13
-
7
-
-
58149399145
-
Phase II trial of neoadjuvant/adjuvant imatinib mesylate (IM) for advanced primary and metastatic/recurrent operable gastrointestinal stromal tumor (GIST): Early results of RTOG 0132/ACRIN 6665
-
1:CAS:528:DC%2BD1MXhvFCjur0%3D 10.1002/jso.21160 18942073
-
BL Eisenberg J Harris CD Blanke GD Demetri MC Heinrich JC Watson JP Hoffman S Okuno JM Kane M von Mehren 2009 Phase II trial of neoadjuvant/adjuvant imatinib mesylate (IM) for advanced primary and metastatic/recurrent operable gastrointestinal stromal tumor (GIST): early results of RTOG 0132/ACRIN 6665 J Surg Oncol 99 42 47 1:CAS:528:DC%2BD1MXhvFCjur0%3D 10.1002/jso.21160 18942073
-
(2009)
J Surg Oncol
, vol.99
, pp. 42-47
-
-
Eisenberg, B.L.1
Harris, J.2
Blanke, C.D.3
Demetri, G.D.4
Heinrich, M.C.5
Watson, J.C.6
Hoffman, J.P.7
Okuno, S.8
Kane, J.M.9
Von Mehren, M.10
-
8
-
-
0344987881
-
A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome
-
1:CAS:528:DC%2BD3sXisVCqtrY%3D 10.1056/NEJMoa025217 12660384
-
J Cools DJ DeAngelo J Gotlib EH Stover RD Legare J Cortes J Kutok J Clark I Galinsky JD Griffin NC Cross A Tefferi J Malone R Alam SL Schrier J Schmid M Rose P Vandenberghe G Verhoef M Boogaerts I Wlodarska H Kantarjian P Marynen SE Coutre R Stone DG Gilliland 2003 A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome N Engl J Med 348 1201 1214 1:CAS:528: DC%2BD3sXisVCqtrY%3D 10.1056/NEJMoa025217 12660384
-
(2003)
N Engl J Med
, vol.348
, pp. 1201-1214
-
-
Cools, J.1
Deangelo, D.J.2
Gotlib, J.3
Stover, E.H.4
Legare, R.D.5
Cortes, J.6
Kutok, J.7
Clark, J.8
Galinsky, I.9
Griffin, J.D.10
Cross, N.C.11
Tefferi, A.12
Malone, J.13
Alam, R.14
Schrier, S.L.15
Schmid, J.16
Rose, M.17
Vandenberghe, P.18
Verhoef, G.19
Boogaerts, M.20
Wlodarska, I.21
Kantarjian, H.22
Marynen, P.23
Coutre, S.E.24
Stone, R.25
Gilliland, D.G.26
more..
-
9
-
-
35348993411
-
The efficacy of imatinib mesylate in patients with FIP1L1-PDGFRalpha- positive hypereosinophilic syndrome. Results of a multicenter prospective study
-
1:CAS:528:DC%2BD2sXhtFGqu7jO 10.3324/haematol.11420 17666373
-
M Baccarani D Cilloni M Rondoni E Ottaviani F Messa S Merante M Tiribelli F Buccisano N Testoni E Gottardi A de Vivo E Giugliano I Iacobucci S Paolini S Soverini G Rosti F Rancati C Astolfi F Pane G Saglio G Martinelli 2007 The efficacy of imatinib mesylate in patients with FIP1L1-PDGFRalpha-positive hypereosinophilic syndrome. Results of a multicenter prospective study Haematologica 92 1173 1179 1:CAS:528:DC%2BD2sXhtFGqu7jO 10.3324/haematol.11420 17666373
-
(2007)
Haematologica
, vol.92
, pp. 1173-1179
-
-
Baccarani, M.1
Cilloni, D.2
Rondoni, M.3
Ottaviani, E.4
Messa, F.5
Merante, S.6
Tiribelli, M.7
Buccisano, F.8
Testoni, N.9
Gottardi, E.10
De Vivo, A.11
Giugliano, E.12
Iacobucci, I.13
Paolini, S.14
Soverini, S.15
Rosti, G.16
Rancati, F.17
Astolfi, C.18
Pane, F.19
Saglio, G.20
Martinelli, G.21
more..
-
10
-
-
0036063077
-
Response of idiopathic hypereosinophilic syndrome to treatment with imatinib mesylate
-
1:CAS:528:DC%2BD38XlsVOmsb8%3D 10.1016/S0145-2126(02)00046-2
-
P Ault J Cortes C Koller ES Kaled H Kantarjian 2002 Response of idiopathic hypereosinophilic syndrome to treatment with imatinib mesylate Leukemia Res 26 881 884 1:CAS:528:DC%2BD38XlsVOmsb8%3D 10.1016/S0145-2126(02) 00046-2
-
(2002)
Leukemia Res
, vol.26
, pp. 881-884
-
-
Ault, P.1
Cortes, J.2
Koller, C.3
Kaled, E.S.4
Kantarjian, H.5
-
11
-
-
0942276859
-
Molecular remission and reversal of myelofibrosis in response to imatinib mesylate treatment in patients with the myeloproliferative variant of hypereosinophilic syndrome
-
1:CAS:528:DC%2BD2cXmsFCjsg%3D%3D 10.1182/blood-2003-08-2798 14504092
-
AD Klion J Robyn C Akin P Noel M Brown M Law DD Metcalfe C Dunbar TB Nutman 2004 Molecular remission and reversal of myelofibrosis in response to imatinib mesylate treatment in patients with the myeloproliferative variant of hypereosinophilic syndrome Blood 103 473 478 1:CAS:528:DC%2BD2cXmsFCjsg%3D%3D 10.1182/blood-2003-08-2798 14504092
-
(2004)
Blood
, vol.103
, pp. 473-478
-
-
Klion, A.D.1
Robyn, J.2
Akin, C.3
Noel, P.4
Brown, M.5
Law, M.6
Metcalfe, D.D.7
Dunbar, C.8
Nutman, T.B.9
-
12
-
-
1342279452
-
Imatinib therapy for hypereosinophilic syndrome and eosinophilia- associated myeloproliferative disorders
-
1:CAS:528:DC%2BD2cXhsVOgurs%3D 10.1016/j.leukres.2003.10.006
-
A Pardanani A Tefferi 2004 Imatinib therapy for hypereosinophilic syndrome and eosinophilia-associated myeloproliferative disorders Leukemia Res 28 Suppl 1 S47 S52 1:CAS:528:DC%2BD2cXhsVOgurs%3D 10.1016/j.leukres.2003.10.006
-
(2004)
Leukemia Res
, vol.28
, Issue.SUPPL. 1
-
-
Pardanani, A.1
Tefferi, A.2
-
13
-
-
30044449181
-
FMS receptor for M-CSF (CSF-1) is sensitive to the kinase inhibitor imatinib and mutation of Asp-802 to Val confers resistance
-
1:CAS:528:DC%2BD28Xht1ejsA%3D%3D 16170366
-
JR Taylor N Brownlow J Domin NJ Dibb 2006 FMS receptor for M-CSF (CSF-1) is sensitive to the kinase inhibitor imatinib and mutation of Asp-802 to Val confers resistance Oncogene 25 147 151 1:CAS:528:DC%2BD28Xht1ejsA%3D%3D 16170366
-
(2006)
Oncogene
, vol.25
, pp. 147-151
-
-
Taylor, J.R.1
Brownlow, N.2
Domin, J.3
Dibb, N.J.4
-
14
-
-
25444493170
-
Inhibition of c-fms by imatinib: Expanding the spectrum of treatment
-
1:CAS:528:DC%2BD28XhslCrtb8%3D 15917650
-
AL Dewar AC Zannettino TP Hughes AB Lyons 2005 Inhibition of c-fms by imatinib: expanding the spectrum of treatment Cell Cycle 4 851 853 1:CAS:528:DC%2BD28XhslCrtb8%3D 15917650
-
(2005)
Cell Cycle
, vol.4
, pp. 851-853
-
-
Dewar, A.L.1
Zannettino, A.C.2
Hughes, T.P.3
Lyons, A.B.4
-
15
-
-
17044403497
-
Macrophage colony-stimulating factor receptor c-fms is a novel target of imatinib
-
1:CAS:528:DC%2BD2MXjtlSmur0%3D 10.1182/blood-2004-10-3967 15637141
-
AL Dewar AC Cambareri AC Zannettino BL Miller KV Doherty TP Hughes AB Lyons 2005 Macrophage colony-stimulating factor receptor c-fms is a novel target of imatinib Blood 105 3127 3132 1:CAS:528:DC%2BD2MXjtlSmur0%3D 10.1182/blood-2004-10-3967 15637141
-
(2005)
Blood
, vol.105
, pp. 3127-3132
-
-
Dewar, A.L.1
Cambareri, A.C.2
Zannettino, A.C.3
Miller, B.L.4
Doherty, K.V.5
Hughes, T.P.6
Lyons, A.B.7
-
16
-
-
55049111858
-
Inhibition of collagen-induced discoidin domain receptor 1 and 2 activation by imatinib, nilotinib and dasatinib
-
1:CAS:528:DC%2BD1cXhtlaqurrP 10.1016/j.ejphar.2008.10.014 18938156
-
E Day B Waters K Spiegel T Alnadaf PW Manley E Buchdunger C Walker G Jarai 2008 Inhibition of collagen-induced discoidin domain receptor 1 and 2 activation by imatinib, nilotinib and dasatinib Eur J Pharmacol 599 44 53 1:CAS:528:DC%2BD1cXhtlaqurrP 10.1016/j.ejphar.2008.10.014 18938156
-
(2008)
Eur J Pharmacol
, vol.599
, pp. 44-53
-
-
Day, E.1
Waters, B.2
Spiegel, K.3
Alnadaf, T.4
Manley, P.W.5
Buchdunger, E.6
Walker, C.7
Jarai, G.8
-
17
-
-
67649946943
-
The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms
-
1:CAS:528:DC%2BD1MXosVGmsbk%3D 10.1016/j.bmcl.2009.06.002 19527930
-
S Parkkila A Innocenti H Kallio M Hilvo A Scozzafava CT Supuran 2009 The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms Bioorg Med Chem Lett 19 4102 4106 1:CAS:528:DC%2BD1MXosVGmsbk%3D 10.1016/j.bmcl.2009.06.002 19527930
-
(2009)
Bioorg Med Chem Lett
, vol.19
, pp. 4102-4106
-
-
Parkkila, S.1
Innocenti, A.2
Kallio, H.3
Hilvo, M.4
Scozzafava, A.5
Supuran, C.T.6
-
18
-
-
0344412948
-
Imatinib mesylate causes hypopigmentation in the skin
-
10.1002/cncr.11812 14635084
-
AS Tsao H Kantarjian J Cortes S O'Brien M Talpaz 2003 Imatinib mesylate causes hypopigmentation in the skin Cancer 98 2483 2487 10.1002/cncr.11812 14635084
-
(2003)
Cancer
, vol.98
, pp. 2483-2487
-
-
Tsao, A.S.1
Kantarjian, H.2
Cortes, J.3
O'Brien, S.4
Talpaz, M.5
-
19
-
-
10744230733
-
Gynaecomastia in men with chronic myeloid leukaemia after imatinib
-
10.1016/S0140-6736(03)13554-4 12801741
-
C Gambacorti-Passerini L Tornaghi F Cavagnini P Rossi F Pecori-Giraldi L Mariani N Cambiaghi E Pogliani G Corneo L Gnessi 2003 Gynaecomastia in men with chronic myeloid leukaemia after imatinib Lancet 361 1954 1956 10.1016/S0140-6736(03)13554-4 12801741
-
(2003)
Lancet
, vol.361
, pp. 1954-1956
-
-
Gambacorti-Passerini, C.1
Tornaghi, L.2
Cavagnini, F.3
Rossi, P.4
Pecori-Giraldi, F.5
Mariani, L.6
Cambiaghi, N.7
Pogliani, E.8
Corneo, G.9
Gnessi, L.10
-
20
-
-
33746845181
-
Cardiotoxicity of the cancer therapeutic agent imatinib mesylate
-
10.1038/nm1446 16862153
-
R Kerkela L Grazette R Yacobi C Iliescu R Patten C Beahm B Walters S Shevtsov S Pesant FJ Clubb A Rosenzweig RN Salomon RA Van Etten J Alroy JB Durand T Force 2006 Cardiotoxicity of the cancer therapeutic agent imatinib mesylate Nat Med 12 908 916 10.1038/nm1446 16862153
-
(2006)
Nat Med
, vol.12
, pp. 908-916
-
-
Kerkela, R.1
Grazette, L.2
Yacobi, R.3
Iliescu, C.4
Patten, R.5
Beahm, C.6
Walters, B.7
Shevtsov, S.8
Pesant, S.9
Clubb, F.J.10
Rosenzweig, A.11
Salomon, R.N.12
Van Etten, R.A.13
Alroy, J.14
Durand, J.B.15
Force, T.16
-
21
-
-
33744992470
-
Reduction of glycosylated hemoglobin with stable insulin levels in a diabetic patient with chronic myeloid leukemia responsive to imatinib
-
16266912
-
M Breccia M Muscaritoli G Alimena 2005 Reduction of glycosylated hemoglobin with stable insulin levels in a diabetic patient with chronic myeloid leukemia responsive to imatinib Haematologica 90 Suppl ECR21 16266912
-
(2005)
Haematologica
, vol.90
, Issue.SUPPL.
, pp. 21
-
-
Breccia, M.1
Muscaritoli, M.2
Alimena, G.3
-
22
-
-
16544383592
-
Imatinib mesylate may improve fasting blood glucose in diabetic Ph+ chronic myelogenous leukemia patients responsive to treatment
-
1:STN:280:DC%2BD2crmvFyrsA%3D%3D 10.1200/JCO.2004.04.217 15542819
-
M Breccia M Muscaritoli Z Aversa F Mandelli G Alimena 2004 Imatinib mesylate may improve fasting blood glucose in diabetic Ph+ chronic myelogenous leukemia patients responsive to treatment J Clin Oncol 22 4653 4655 1:STN:280:DC%2BD2crmvFyrsA%3D%3D 10.1200/JCO.2004.04.217 15542819
-
(2004)
J Clin Oncol
, vol.22
, pp. 4653-4655
-
-
Breccia, M.1
Muscaritoli, M.2
Aversa, Z.3
Mandelli, F.4
Alimena, G.5
-
23
-
-
14744281398
-
Imatinib and regression of type 2 diabetes
-
1:CAS:528:DC%2BD2MXit1WrtL4%3D 10.1056/NEJM200503103521023 15758023
-
D Veneri M Franchini E Bonora 2005 Imatinib and regression of type 2 diabetes N Engl J Med 352 1049 1050 1:CAS:528:DC%2BD2MXit1WrtL4%3D 10.1056/NEJM200503103521023 15758023
-
(2005)
N Engl J Med
, vol.352
, pp. 1049-1050
-
-
Veneri, D.1
Franchini, M.2
Bonora, E.3
-
24
-
-
38349064869
-
Imatinib mesylate improves insulin sensitivity and glucose disposal rates in rats fed a high-fat diet
-
10.1042/CS20070122 17868036
-
R Hagerkvist L Jansson N Welsh 2008 Imatinib mesylate improves insulin sensitivity and glucose disposal rates in rats fed a high-fat diet Clin Sci 114 65 71 10.1042/CS20070122 17868036
-
(2008)
Clin Sci
, vol.114
, pp. 65-71
-
-
Hagerkvist, R.1
Jansson, L.2
Welsh, N.3
-
25
-
-
33846842100
-
Amelioration of diabetes by imatinib mesylate (Gleevec): Role of beta-cell NF-kappaB activation and anti-apoptotic preconditioning
-
10.1096/fj.06-6910com 17135364
-
R Hagerkvist S Sandler D Mokhtari N Welsh 2007 Amelioration of diabetes by imatinib mesylate (Gleevec): role of beta-cell NF-kappaB activation and anti-apoptotic preconditioning FASEB J 21 618 628 10.1096/fj.06-6910com 17135364
-
(2007)
FASEB J
, vol.21
, pp. 618-628
-
-
Hagerkvist, R.1
Sandler, S.2
Mokhtari, D.3
Welsh, N.4
-
26
-
-
33751220209
-
Imatinib mesylate (Gleevec) protects against streptozotocin-induced diabetes and islet cell death in vitro
-
10.1016/j.cellbi.2006.08.006 17020808
-
R Hagerkvist N Makeeva S Elliman N Welsh 2006 Imatinib mesylate (Gleevec) protects against streptozotocin-induced diabetes and islet cell death in vitro Cell Biol Int 30 1013 1017 10.1016/j.cellbi.2006.08.006 17020808
-
(2006)
Cell Biol Int
, vol.30
, pp. 1013-1017
-
-
Hagerkvist, R.1
Makeeva, N.2
Elliman, S.3
Welsh, N.4
-
27
-
-
33845452829
-
Imatinib mesylate, increased bone formation, and secondary hyperparathyroidism
-
1:CAS:528:DC%2BD28Xht12ntb%2FF 10.1056/NEJMc062388 17151376
-
A Grey S O'Sullivan IR Reid P Browett 2006 Imatinib mesylate, increased bone formation, and secondary hyperparathyroidism N Engl J Med 355 2494 2495 1:CAS:528:DC%2BD28Xht12ntb%2FF 10.1056/NEJMc062388 17151376
-
(2006)
N Engl J Med
, vol.355
, pp. 2494-2495
-
-
Grey, A.1
O'Sullivan, S.2
Reid, I.R.3
Browett, P.4
-
28
-
-
77949311903
-
Dysregulation of bone remodeling by imatinib mesylate
-
1:CAS:528:DC%2BC3cXhs1Giur8%3D 10.1182/blood-2009-08-237404 19890095
-
K Vandyke S Fitter AL Dewar TP Hughes AC Zannettino 2010 Dysregulation of bone remodeling by imatinib mesylate Blood 115 766 774 1:CAS:528: DC%2BC3cXhs1Giur8%3D 10.1182/blood-2009-08-237404 19890095
-
(2010)
Blood
, vol.115
, pp. 766-774
-
-
Vandyke, K.1
Fitter, S.2
Dewar, A.L.3
Hughes, T.P.4
Zannettino, A.C.5
-
29
-
-
65249162967
-
Decreased bone turnover despite persistent secondary hyperparathyroidism during prolonged treatment with imatinib
-
10.1210/jc.2008-2324 19174494
-
S O'Sullivan A Horne D Wattie F Porteous K Callon G Gamble P Ebeling P Browett A Grey 2009 Decreased bone turnover despite persistent secondary hyperparathyroidism during prolonged treatment with imatinib J Clin Endocrinol Metab 94 1131 1136 10.1210/jc.2008-2324 19174494
-
(2009)
J Clin Endocrinol Metab
, vol.94
, pp. 1131-1136
-
-
O'Sullivan, S.1
Horne, A.2
Wattie, D.3
Porteous, F.4
Callon, K.5
Gamble, G.6
Ebeling, P.7
Browett, P.8
Grey, A.9
-
30
-
-
33646482407
-
Altered bone and mineral metabolism in patients receiving imatinib mesylate
-
1:CAS:528:DC%2BD28XksFGhs7s%3D 10.1056/NEJMoa051140 16687713
-
E Berman M Nicolaides RG Maki M Fleisher S Chanel K Scheu BA Wilson G Heller NP Sauter 2006 Altered bone and mineral metabolism in patients receiving imatinib mesylate N Engl J Med 354 2006 2013 1:CAS:528:DC%2BD28XksFGhs7s%3D 10.1056/NEJMoa051140 16687713
-
(2006)
N Engl J Med
, vol.354
, pp. 2006-2013
-
-
Berman, E.1
Nicolaides, M.2
Maki, R.G.3
Fleisher, M.4
Chanel, S.5
Scheu, K.6
Wilson, B.A.7
Heller, G.8
Sauter, N.P.9
-
31
-
-
41949120243
-
Long-term imatinib therapy promotes bone formation in CML patients
-
1:CAS:528:DC%2BD1cXivFakt74%3D 10.1182/blood-2007-07-104281 18042796
-
S Fitter AL Dewar P Kostakis LB To TP Hughes MM Roberts K Lynch B Vernon-Roberts AC Zannettino 2008 Long-term imatinib therapy promotes bone formation in CML patients Blood 111 2538 2547 1:CAS:528:DC%2BD1cXivFakt74%3D 10.1182/blood-2007-07-104281 18042796
-
(2008)
Blood
, vol.111
, pp. 2538-2547
-
-
Fitter, S.1
Dewar, A.L.2
Kostakis, P.3
To, L.B.4
Hughes, T.P.5
Roberts, M.M.6
Lynch, K.7
Vernon-Roberts, B.8
Zannettino, A.C.9
-
32
-
-
34247501288
-
Imatinib mesylate induces hypophosphatemia in patients with chronic myeloid leukemia in late chronic phase, and this effect is associated with response
-
1:CAS:528:DC%2BD2sXlsVKqsbg%3D 10.1002/ajh.20778 17117416
-
S Osorio AG Noblejas A Duran JL Steegmann 2007 Imatinib mesylate induces hypophosphatemia in patients with chronic myeloid leukemia in late chronic phase, and this effect is associated with response Am J Hematol 82 394 395 1:CAS:528:DC%2BD2sXlsVKqsbg%3D 10.1002/ajh.20778 17117416
-
(2007)
Am J Hematol
, vol.82
, pp. 394-395
-
-
Osorio, S.1
Noblejas, A.G.2
Duran, A.3
Steegmann, J.L.4
-
33
-
-
62149144093
-
Effects of imatinib mesylate in osteoblastogenesis
-
1:CAS:528:DC%2BD1MXjsVOhsbY%3D 10.1016/j.exphem.2008.12.008 19302920
-
D Tibullo C Giallongo P La Cava S Berretta F Stagno A Chiarenza C Conticello GA Palumbo F Di Raimondo 2009 Effects of imatinib mesylate in osteoblastogenesis Exp Hematol 37 461 468 1:CAS:528:DC%2BD1MXjsVOhsbY%3D 10.1016/j.exphem.2008.12.008 19302920
-
(2009)
Exp Hematol
, vol.37
, pp. 461-468
-
-
Tibullo, D.1
Giallongo, C.2
La Cava, P.3
Berretta, S.4
Stagno, F.5
Chiarenza, A.6
Conticello, C.7
Palumbo, G.A.8
Di Raimondo, F.9
-
34
-
-
34249025381
-
Inhibition of platelet-derived growth factor receptor beta by imatinib mesylate suppresses proliferation and alters differentiation of human mesenchymal stem cells in vitro
-
1:CAS:528:DC%2BD2sXnt1GrtL8%3D 10.1111/j.1365-2184.2007.00438.x 17531080
-
F Fierro T Illmer D Jing E Schleyer G Ehninger S Boxberger M Bornhauser 2007 Inhibition of platelet-derived growth factor receptor beta by imatinib mesylate suppresses proliferation and alters differentiation of human mesenchymal stem cells in vitro Cell Prolif 40 355 366 1:CAS:528: DC%2BD2sXnt1GrtL8%3D 10.1111/j.1365-2184.2007.00438.x 17531080
-
(2007)
Cell Prolif
, vol.40
, pp. 355-366
-
-
Fierro, F.1
Illmer, T.2
Jing, D.3
Schleyer, E.4
Ehninger, G.5
Boxberger, S.6
Bornhauser, M.7
-
35
-
-
38449096127
-
Imatinib promotes osteoblast differentiation by inhibiting PDGFR signaling and inhibits osteoclastogenesis by both direct and stromal cell-dependent mechanisms
-
10.1359/jbmr.070719 17663639
-
S O'Sullivan D Naot K Callon F Porteous A Horne D Wattie M Watson J Cornish P Browett A Grey 2007 Imatinib promotes osteoblast differentiation by inhibiting PDGFR signaling and inhibits osteoclastogenesis by both direct and stromal cell-dependent mechanisms J Bone Miner Res 22 1679 1689 10.1359/jbmr.070719 17663639
-
(2007)
J Bone Miner Res
, vol.22
, pp. 1679-1689
-
-
O'Sullivan, S.1
Naot, D.2
Callon, K.3
Porteous, F.4
Horne, A.5
Wattie, D.6
Watson, M.7
Cornish, J.8
Browett, P.9
Grey, A.10
-
37
-
-
33750605907
-
Ability of breast cancer cell lines to stimulate bone resorbing activity of mature osteoclasts correlates with an anti-apoptotic effect mediated by macrophage colony stimulating factor
-
1:CAS:528:DC%2BD28XhtFKmtr3P 10.1007/s10495-006-9507-z 16927019
-
M Gallet R Mentaverri N Sevenet M Brazier S Kamel 2006 Ability of breast cancer cell lines to stimulate bone resorbing activity of mature osteoclasts correlates with an anti-apoptotic effect mediated by macrophage colony stimulating factor Apoptosis 11 1909 1921 1:CAS:528:DC%2BD28XhtFKmtr3P 10.1007/s10495-006-9507-z 16927019
-
(2006)
Apoptosis
, vol.11
, pp. 1909-1921
-
-
Gallet, M.1
Mentaverri, R.2
Sevenet, N.3
Brazier, M.4
Kamel, S.5
-
38
-
-
33750456241
-
Imatinib mesylate (Gleevec) enhances mature osteoclast apoptosis and suppresses osteoclast bone resorbing activity
-
1:CAS:528:DC%2BD28XhtFKmtbbO 10.1016/j.ejphar.2006.09.007 17049513
-
I El Hajj Dib M Gallet R Mentaverri N Sevenet M Brazier S Kamel 2006 Imatinib mesylate (Gleevec) enhances mature osteoclast apoptosis and suppresses osteoclast bone resorbing activity Eur J Pharmacol 551 27 33 1:CAS:528:DC%2BD28XhtFKmtbbO 10.1016/j.ejphar.2006.09.007 17049513
-
(2006)
Eur J Pharmacol
, vol.551
, pp. 27-33
-
-
El Hajj Dib, I.1
Gallet, M.2
Mentaverri, R.3
Sevenet, N.4
Brazier, M.5
Kamel, S.6
-
39
-
-
46849094125
-
Increased cortical bone mineralization in imatinib treated patients with chronic myelogenous leukemia
-
10.3324/haematol.12373 18508797
-
S Jonsson B Olsson C Ohlsson M Lorentzon D Mellstrom H Wadenvik 2008 Increased cortical bone mineralization in imatinib treated patients with chronic myelogenous leukemia Haematologica 93 1101 1103 10.3324/haematol.12373 18508797
-
(2008)
Haematologica
, vol.93
, pp. 1101-1103
-
-
Jonsson, S.1
Olsson, B.2
Ohlsson, C.3
Lorentzon, M.4
Mellstrom, D.5
Wadenvik, H.6
-
40
-
-
0032907306
-
Selective tyrosine kinase inhibitor for the platelet-derived growth factor receptor in vitro inhibits smooth muscle cell proliferation after reinjury of arterial intima in vivo
-
1:CAS:528:DyaK1MXktFemtrc%3D 10.1023/A:1007700629728 10372232
-
M Myllarniemi J Frosen LG Calderon Ramirez E Buchdunger K Lemstrom P Hayry 1999 Selective tyrosine kinase inhibitor for the platelet-derived growth factor receptor in vitro inhibits smooth muscle cell proliferation after reinjury of arterial intima in vivo Cardiovasc Drugs Ther 13 159 168 1:CAS:528:DyaK1MXktFemtrc%3D 10.1023/A:1007700629728 10372232
-
(1999)
Cardiovasc Drugs Ther
, vol.13
, pp. 159-168
-
-
Myllarniemi, M.1
Frosen, J.2
Calderon Ramirez, L.G.3
Buchdunger, E.4
Lemstrom, K.5
Hayry, P.6
-
41
-
-
33745596398
-
Imatinib mesylate inhibits osteoclastogenesis and joint destruction in rats with collagen-induced arthritis (CIA)
-
1:CAS:528:DC%2BD28XmsVShtr4%3D 10.1007/s00774-006-0684-1 16816921
-
W Ando J Hashimoto A Nampei H Tsuboi K Tateishi T Ono N Nakamura T Ochi H Yoshikawa 2006 Imatinib mesylate inhibits osteoclastogenesis and joint destruction in rats with collagen-induced arthritis (CIA) J Bone Miner Metab 24 274 282 1:CAS:528:DC%2BD28XmsVShtr4%3D 10.1007/s00774-006-0684-1 16816921
-
(2006)
J Bone Miner Metab
, vol.24
, pp. 274-282
-
-
Ando, W.1
Hashimoto, J.2
Nampei, A.3
Tsuboi, H.4
Tateishi, K.5
Ono, T.6
Nakamura, N.7
Ochi, T.8
Yoshikawa, H.9
-
42
-
-
0021445363
-
Practical cone-beam algorithm
-
10.1364/JOSAA.1.000612
-
LA Feldkamp 1984 Practical cone-beam algorithm J Opt Soc Am A Opt Image Sci Vis 1 612 619 10.1364/JOSAA.1.000612
-
(1984)
J Opt Soc Am A Opt Image Sci Vis
, vol.1
, pp. 612-619
-
-
Feldkamp, L.A.1
-
43
-
-
18044371462
-
An improved segmentation method for in vivo microCT imaging
-
10.1359/JBMR.040705 15355559
-
JH Waarsing JS Day H Weinans 2004 An improved segmentation method for in vivo microCT imaging J Bone Miner Res 19 1640 1650 10.1359/JBMR.040705 15355559
-
(2004)
J Bone Miner Res
, vol.19
, pp. 1640-1650
-
-
Waarsing, J.H.1
Day, J.S.2
Weinans, H.3
-
44
-
-
2942730560
-
Quantification of bone microarchitecture with the structure model index
-
10.1080/01495739708936692 11264794
-
T Hildebrand P Ruegsegger 1997 Quantification of bone microarchitecture with the structure model index Comput Methods Biomech Biomed Engin 1 15 23 10.1080/01495739708936692 11264794
-
(1997)
Comput Methods Biomech Biomed Engin
, vol.1
, pp. 15-23
-
-
Hildebrand, T.1
Ruegsegger, P.2
-
45
-
-
0026721345
-
Trabecular bone pattern factor-a new parameter for simple quantification of bone microarchitecture
-
1:STN:280:DyaK3s%2FgtFKmtg%3D%3D 10.1016/8756-3282(92)90078-B 1389573
-
M Hahn M Vogel M Pompesius-Kempa G Delling 1992 Trabecular bone pattern factor-a new parameter for simple quantification of bone microarchitecture Bone 13 327 330 1:STN:280:DyaK3s%2FgtFKmtg%3D%3D 10.1016/8756-3282(92)90078-B 1389573
-
(1992)
Bone
, vol.13
, pp. 327-330
-
-
Hahn, M.1
Vogel, M.2
Pompesius-Kempa, M.3
Delling, G.4
-
46
-
-
0023488581
-
Bone histomorphometry: Standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee
-
1:STN:280:DyaL1czjvVemsQ%3D%3D 10.1002/jbmr.5650020617 3455637
-
AM Parfitt MK Drezner FH Glorieux JA Kanis H Malluche PJ Meunier SM Ott RR Recker 1987 Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee J Bone Miner Res 2 595 610 1:STN:280:DyaL1czjvVemsQ%3D%3D 10.1002/jbmr.5650020617 3455637
-
(1987)
J Bone Miner Res
, vol.2
, pp. 595-610
-
-
Parfitt, A.M.1
Drezner, M.K.2
Glorieux, F.H.3
Kanis, J.A.4
Malluche, H.5
Meunier, P.J.6
Ott, S.M.7
Recker, R.R.8
-
47
-
-
43149117061
-
Relationships between fat and bone
-
1:STN:280:DC%2BD1c3hslGlug%3D%3D 10.1007/s00198-007-0492-z 17965817
-
IR Reid 2008 Relationships between fat and bone Osteoporos Int 19 595 606 1:STN:280:DC%2BD1c3hslGlug%3D%3D 10.1007/s00198-007-0492-z 17965817
-
(2008)
Osteoporos Int
, vol.19
, pp. 595-606
-
-
Reid, I.R.1
-
48
-
-
0242413030
-
Recombinant human parathyroid hormone (1-34) [teriparatide] improves both cortical and cancellous bone structure
-
1:CAS:528:DC%2BD3sXptVyiu74%3D 10.1359/jbmr.2003.18.11.1932 14606504
-
Y Jiang JJ Zhao BH Mitlak O Wang HK Genant EF Eriksen 2003 Recombinant human parathyroid hormone (1-34) [teriparatide] improves both cortical and cancellous bone structure J Bone Miner Res 18 1932 1941 1:CAS:528: DC%2BD3sXptVyiu74%3D 10.1359/jbmr.2003.18.11.1932 14606504
-
(2003)
J Bone Miner Res
, vol.18
, pp. 1932-1941
-
-
Jiang, Y.1
Zhao, J.J.2
Mitlak, B.H.3
Wang, O.4
Genant, H.K.5
Eriksen, E.F.6
-
49
-
-
37549039804
-
Effects of intravenous zoledronic acid once yearly on bone remodeling and bone structure
-
1:CAS:528:DC%2BD1cXhtVCmt7c%3D 10.1359/jbmr.070906 17892374
-
RR Recker PD Delmas J Halse IR Reid S Boonen PA Garcia-Hernandez J Supronik EM Lewiecki L Ochoa P Miller H Hu P Mesenbrink F Hartl J Gasser EF Eriksen 2008 Effects of intravenous zoledronic acid once yearly on bone remodeling and bone structure J Bone Miner Res 23 6 16 1:CAS:528: DC%2BD1cXhtVCmt7c%3D 10.1359/jbmr.070906 17892374
-
(2008)
J Bone Miner Res
, vol.23
, pp. 6-16
-
-
Recker, R.R.1
Delmas, P.D.2
Halse, J.3
Reid, I.R.4
Boonen, S.5
Garcia-Hernandez, P.A.6
Supronik, J.7
Lewiecki, E.M.8
Ochoa, L.9
Miller, P.10
Hu, H.11
Mesenbrink, P.12
Hartl, F.13
Gasser, J.14
Eriksen, E.F.15
-
50
-
-
33846070788
-
In reply to "cardiotoxicity of the cancer therapeutic agent imatinib mesylate"
-
author reply 15-16
-
Hatfield A, Owen S, Pilot PR (2007) In reply to "Cardiotoxicity of the cancer therapeutic agent imatinib mesylate". Nat Med 13:13, author reply 15-16
-
(2007)
Nat Med
, vol.13
, pp. 13
-
-
Hatfield, A.1
Owen, S.2
Pilot, P.R.3
|