Development and validation of a simple cell-based fluorescence assay for dipeptidyl peptidase 1 (DPP1) activity

Journal of Biomolecular Screening

Volumn 16, Issue 1, 2011, Pages 36-43

  Thong, Bob ^a   Pilling, James ^a   Ainscow, Edward ^a   Beri, Raj ^a   Unitt, John ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

cathepsin C; cell based assay; DPP1; fluorescence; H Gly Phe AFC; lysosome; THP 1 cells

Indexed keywords

DIPEPTIDYL PEPTIDASE I;

ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SUBSTRATE; FLUORESCENCE ANALYSIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

AMINOCOUMARINS; ANIMALS; BIOLOGICAL ASSAY; CATHEPSIN C; CELL LINE, TUMOR; DIPEPTIDES; FLUORESCENCE; FLUORESCENT DYES; HUMANS; INTRACELLULAR SPACE; LYSOSOMES; SUBSTRATE SPECIFICITY;

EID: 78951474607     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057110385228     Document Type: Article

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