Prolactin Serum Levels During Alcohol Withdrawal Are Associated With the Severity of Alcohol Dependence and Withdrawal Symptoms

Alcoholism: Clinical and Experimental Research

Volumn 35, Issue 2, 2011, Pages 235-239

  Wilhelm, Julia ^a,b   Heberlein, Annemarie ^a,b   Karagülle, Deniz ^a   Gröschl, Michael ^b   Kornhuber, Johannes ^b   Riera, Rafael ^c   Frieling, Helge ^a,b   Bleich, Stefan ^a,b   Hillemacher, Thomas ^a,b  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^c Clinic for Psychiatry   (Germany)

Author keywords

Addiction; Alcohol Dependence; Craving; Prolactin; Withdrawal

Indexed keywords

PROLACTIN;

ALCOHOL ABSTINENCE; ALCOHOL WITHDRAWAL; ALCOHOLISM; ANXIETY; ARTICLE; CONTROLLED STUDY; DEPRESSION; DISEASE ASSOCIATION; DISEASE SEVERITY; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; PRIORITY JOURNAL; PROLACTIN BLOOD LEVEL; PSYCHOLOGIC ASSESSMENT; STRUCTURED INTERVIEW; WITHDRAWAL SYNDROME;

ALCOHOLISM; DOPAMINE; HUMANS; LONGITUDINAL STUDIES; MALE; PROLACTIN; SUBSTANCE WITHDRAWAL SYNDROME; TEMPERANCE;

EID: 78851471926     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2010.01339.x     Document Type: Article

References (36)

1. Anton RF, Moak DH, Latham P (1995) The Obsessive Compulsive Drinking Scale: a self-rated instrument for the quantification of thoughts about alcohol and drinking behavior. Alcohol Clin Exp Res 19:92-99.
2. Beck ATWCH, Mendelson M, Mock J, Erbaugh J (1961) An inventory for measuring depression. Arch Gen Psychiatry 4:561-571.
3. Ben-Jonathan N, Hnasko R (2001) Dopamine as a prolactin (PRL) inhibitor. Endocr Rev 22:724-763.
4. Bleich S, Carl M, Bayerlein K, Reulbach U, Biermann T, Hillemacher T, Bönsch D, Kornhuber J (2005) Evidence of increased homocysteine levels in alcoholism: the Franconian alcoholism research studies (FARS). Alcohol Clin Exp Res 29:334-336.
5. Bleich S, Degner D, Javaheripour K, Kurth C, Kornhuber J (2000) Homocysteine and alcoholism. J Neural Transm Suppl 60:187-196.
6. Bregonzio C, Moreno GN, Cabrera RJ, Donoso AO (2004) NMDA receptors in the medial zona incerta stimulate luteinizing hormone and prolactin release. Cell Mol Neurobiol 24:331-342.
7. Bregonzio C, Navarro CE, Donoso AO (1998) NMDA receptor antagonists block stress-induced prolactin release in female rats at estrus. Eur J Pharmacol 350:259-265.
8. Davis KM, Wu JY (2001) Role of glutamatergic and GABAergic systems in alcoholism. J Biomed Sci 8:7-19.
9. De A, Boyadjieva N, Oomizu S, Sarkar DK (2002) Ethanol induces hyperprolactinemia by increasing prolactin release and lactotrope growth in female rats. Alcohol Clin Exp Res 26:1420-1429.
10. Durham RA, Eaton MJ, Moore KE, Lookingland KJ (1997) Effects of selective activation of dopamine D2 and D3 receptors on prolactin secretion and the activity of tuberoinfundibular dopamine neurons. Eur J Pharmacol 335:37-42.
11. Emanuele NV, Lapaglia N, Emanuele MA (2001) Impact of acute and chronic ethanol exposure on prolactin in both male and female rats. Endocrine 16:29-37.
12. Flannery BA, Volpicelli JR, Pettinati HM (1999) Psychometric properties of the Penn Alcohol Craving Scale. Alcohol Clin Exp Res 23:1289-1295.
13. Frias J, Rodriguez R, Torres JM, Ruiz E, Ortega E (2000) Effects of acute alcohol intoxication on pituitary-gonadal axis hormones, pituitary-adrenal axis hormones, beta-endorphin and prolactin in human adolescents of both sexes. Life Sci 67:1081-1086.
14. Frias J, Torres JM, Miranda MT, Ruiz E, Ortega E (2002) Effects of acute alcohol intoxication on pituitary-gonadal axis hormones, pituitary-adrenal axis hormones, beta-endorphin and prolactin in human adults of both sexes. Alcohol Alcohol 37:169-173.
15. Gessa GL, Muntoni F, Collu M, Vargiu L, Mereu G (1985) Low doses of ethanol activate dopaminergic neurons in the ventral tegmental area. Brain Res 348:201-203.
16. Heinz A, Rommelspacher H, Gräf KJ, Kürten I, Otto M, Baumgartner A (1995) Hypothalamic-pituitary-gonadal axis, prolactin, and cortisol in alcoholics during withdrawal and after three weeks of abstinence: comparison with healthy control subjects. Psychiatry Res 56:81-95.
17. Hillemacher T, Bayerlein K, Frieling H, Wilhelm J, Ziegenbein M, Kornhuber J, Bleich S (2007a) Elevated prolactin serum levels and history of alcohol withdrawal seizures. J Psychiatr Res 41:702-706.
18. Hillemacher T, Bayerlein K, Wilhelm J, Bönsch D, Poleo D, Sperling W, Kornhuber J, Bleich S (2006a) Recurrent detoxifications are associated with craving in patients classified as type 1 according to Lesch's typology. Alcohol Alcohol 41:66-69.
19. Hillemacher T, Bayerlein K, Wilhelm J, Frieling H, Sperling W, Kornhuber J, Bleich S (2006b) Prolactin Serum Levels and Alcohol Craving - An Analysis Using Lesch's Typology. Neuropsychobiology 53:133-136.
20. Hillemacher T, Bayerlein K, Wilhelm J, Reulbach U, Frieling H, Bönsch D, Kornhuber J, Bleich S (2005) Alteration of prolactin serum levels during alcohol withdrawal correlates with craving in female patients. Addict Biol 10:337-343.
21. Hillemacher T, Frieling H, Bayerlein K, Wilhelm J, Kornhuber J, Bleich S (2007b) Biological markers to predict previous alcohol withdrawal seizures: a risk assessment. J Neural Transm 114:151-154.
22. Imperato A, Di Chiara G (1986) Preferential stimulation of dopamine release in the nucleus accumbens of freely moving rats by ethanol. J Pharmacol Exp Ther 239:219-228.
23. John U, Hapke U, Rumpf H-J ed (2001) SESA-Skala zur Erfassung der Schwere der Alkoholabhängigkeit. Hogrefe, Göttingen.
24. Kutscher S, Heise DJ, Banger M, Saller B, Michel MC, Gastpar M, Schedlowski M, Exton M (2002) Concomitant endocrine and immune alterations during alcohol intoxication and acute withdrawal in alcohol-dependent subjects. Neuropsychobiology 45:144-149.
25. Larson ER, Ariano MA (1995) D3 and D2 dopamine receptors: visualization of cellular expression patterns in motor and limbic structures. Synapse 20:325-337.
26. Mayfield D, McLeod G, Hall P (1974) The CAGE questionnaire: validation of a new alcoholism screening instrument. Am J Psychiatry 131:1121-1123.
27. Miller F, Barasch A, Sacks M, Levitan J, Ashcroft L (1986) Serum prolactin correlates with depressed mood during alcohol withdrawal. Drug Alcohol Depend 17:331-338.
28. Pinilla L, Gonzalez D, Tena-Sempere M, Aguilar R, Aguilar E (1996) Effects of N-methyl-D-aspartate and kainic acid on prolactin secretion in prepubertal female rats. Eur J Endocrinol 135:464-468.
29. Saunders JB, Aasland OG, Babor TF, de la Fuente JR, Grant M (1993) Development of the alcohol use disorders identification test (AUDIT): WHO collaborative project on early detection of persons with harmful alcohol consumption-II. Addiction 88:791-804.
30. Schuckit MA, Gold E, Risch C (1987) Serum prolactin levels in sons of alcoholics and control subjects. Am J Psychiatry 144:854-859.
31. Schuckit MA, Parker DC, Rossman LR (1983) Ethanol-related prolactin responses and risk for alcoholism. Biol Psychiatry 18:1153-1159.
32. Spielberger CD, Gorusch RL, Lushene RE (1970) STAI Manual. Consulting Psychologists Press, Inc, Palo Alto, CA.
33. Sullivan JT, Sykora K, Schneiderman J, Naranjo CA, Sellers EM (1989) Assessment of alcohol withdrawal: the revised clinical institute withdrawal assessment for alcohol scale (CIWA-Ar). Br J Addict 84:1353-1357.
34. Tashjian AJ, Barowsky N, Jensen D (1971) Thyrotropin releasing hormone: direct evidence for stimulation of prolactin production by pituitary cells in culture. Biochem Biophys Res Commun 43:516-523.
35. Willner P, Field M, Pitts K, Reeve G (1998) Mood, cue and gender influences on motivation, craving and liking for alcohol in recreational drinkers. Behav Pharmacol 9:631-642.
36. Zimmermann US, Buchmann AF, Spring C, Uhr M, Holsboer F, Wittchen HU (2009) Ethanol administration dampens the prolactin response to psychosocial stress exposure in sons of alcohol-dependent fathers. Psychoneuroendocrinology 34:996-1003.