NF-κB subunits are differentially distributed in cells of lumbar dorsal root ganglia in naïve and diabetic rats

Neuroscience Letters

Volumn 490, Issue 1, 2011, Pages 41-45

  Berti Mattera, L N ^a   Larkin, B ^a   Hourmouzis, Z ^a   Kern, T S ^a   Siegel, R E ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

B; Diabetes; DRG; Neuropathy; NF B subunit distribution; Sensory neurons

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN P50; SYNAPTOTAGMIN I;

ALLODYNIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; DIABETIC NEUROPATHY; IMMUNOHISTOCHEMISTRY; LUMBAR SPINE; MOLECULAR PATHOLOGY; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SPINAL GANGLION; STREPTOZOCIN DIABETES;

ANALYSIS OF VARIANCE; ANIMALS; CALCITONIN GENE-RELATED PEPTIDE; CELL NUCLEUS; CYTOPLASM; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEUROPATHIES; GANGLIA, SPINAL; HYPERALGESIA; LECTINS; LUMBOSACRAL REGION; NF-KAPPA B; PAIN MEASUREMENT; PAIN THRESHOLD; PROTEIN SUBUNITS; PROTO-ONCOGENE PROTEINS C-REL; RATS; RATS, INBRED LEW; SENSORY RECEPTOR CELLS;

EID: 78751701843     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.12.022     Document Type: Article

References (32)

1. Albers K.M., Woodbury C.J., Ritter A.M., Davis B.M., Koerber H.R. Glial cell-line-derived neurotrophic factor expression in skin alters the mechanical sensitivity of cutaneous nociceptors. J. Neurosci. 2006, 26:2981-2990.
2. Aoki Y., Takahashi Y., Ohtori S., Moriya H., Takahashi K. Distribution and immunocytochemical characterization of dorsal root ganglion neurons innervating the lumbar intervertebral disc in rats: a review. Life Sci. 2004, 74:2627-2642.
3. Berti-Mattera L.N., Gariepy C.E., Burke R.M., Hall A.K. Reduced expression of endothelin B receptors and mechanical hyperalgesia in experimental chronic diabetes. Exp. Neurol. 2006, 201:399-406.
4. Berti-Mattera L.N., Kern T.S., Siegel R.E., Nemet I., Mitchell R. Sulfasalazine blocks the development of tactile allodynia in diabetic rats. Diabetes 2008, 57:2801-2808.
5. Dublin P., Hanani M. Satellite glial cells in sensory ganglia: their possible contribution to inflammatory pain. Brain Behav. Immun. 2007, 21:592-598.
6. Fan W., Cooper N.G., Glutamate-induced NFkappaB activation in the retina. Invest. Ophthalmol. Vis. Sci. 2009, 50:917-925.
7. Fernyhough P., Smith D.R., Schapansky J., Van Der Ploeg R., Gardiner N.J., Tweed C.W., Kontos A., Freeman L., Purves-Tyson T.D., Glazner G.W. Activation of nuclear factor-kappaB via endogenous tumor necrosis factor alpha regulates survival of axotomized adult sensory neurons. J. Neurosci. 2005, 25:1682-1690.
8. Fu E.S., Zhang Y.P., Sagen J., Candiotti K.A., Morton P.D., Liebl D.J., Bethea J.R., Brambilla R. Transgenic inhibition of glial NF-kappa B reduces pain behavior and inflammation after peripheral nerve injury. Pain 2010, 148:509-518.
9. Hamanoue M., Middleton G., Wyatt S., Jaffray E., Hay R.T., Davies A.M. p75-mediated NF-kappaB activation enhances the survival response of developing sensory neurons to nerve growth factor. Mol. Cell. Neurosci. 1999, 14:28-40.
10. Hayden M.S., Ghosh S. Signaling to NF-kappaB. Genes Dev. 2004, 18:2195-2224.
11. Hsieh Y.H., Dick T.E., Siegel R.E. Adaptation to hypobaric hypoxia involves GABAA receptors in the pons. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2008, 294:R549-557.
12. Hubert T., Bourane S., Venteo S., Mechaly I., Puech S., Valmier J., Carroll P., Fichard-Carroll A. Fibroblast growth factor homologous factor 1 (FHF1) is expressed in a subpopulation of calcitonin gene-related peptide-positive nociceptive neurons in the murine dorsal root ganglia. J. Comp. Neurol. 2008, 507:1588-1601.
13. Kaltschmidt B., Kaltschmidt C. NF-kappaB in the nervous system. Cold Spring. Harb. Perspect. Biol. 2009, 1:a001271.
14. Kaltschmidt C., Kaltschmidt B., Neumann H., Wekerle H., Baeuerle P.A. Constitutive NF-kappa B activity in neurons. Mol. Cell. Biol. 1994, 14:3981-3992.
15. Ma W., Bisby M.A. Increased activation of nuclear factor kappa B in rat lumbar dorsal root ganglion neurons following partial sciatic nerve injuries. Brain Res. 1998, 797:243-254.
16. Malek R., Borowicz K.K., Jargiello M., Czuczwar S.J. Role of nuclear factor kappaB in the central nervous system. Pharmacol. Rep. 2007, 59:25-33.
17. Mattson M.P. NF-kappaB in the survival and plasticity of neurons. Neurochem. Res. 2005, 30:883-893.
18. Memet S. NF-kappaB functions in the nervous system: from development to disease. Biochem. Pharmacol. 2006, 72:1180-1195.
19. Pereira S.G., Oakley F. Nuclear factor-kappaB1: regulation and function. Int. J. Biochem. Cell Biol. 2008, 40:1425-1430.
20. Perkins N.D. Integrating cell-signalling pathways with NF-kappaB and IKK function. Nat. Rev. Mol. Cell Biol. 2007, 8:49-62.
21. Pizzi M., Sarnico I., Lanzillotta A., Battistin L., Spano P. Post-ischemic brain damage: NF-kappaB dimer heterogeneity as a molecular determinant of neuron vulnerability. FEBS J. 2009, 276:27-35.
22. Purves T.D., Tomlinson D.R. Diminished transcription factor survival signals in dorsal root ganglia in rats with streptozotocin-induced diabetes. Ann. N.Y. Acad. Sci. 2002, 973:472-476.
23. Sarnico I., Lanzillotta A., Boroni F., Benarese M., Alghisi M., Schwaninger M., Inta I., Battistin L., Spano P., Pizzi M. NF-kappaB p50/RelA and c-Rel-containing dimers: opposite regulators of neuron vulnerability to ischaemia. J. Neurochem. 2009, 108:475-485.
24. Schwaninger M., Inta I., Herrmann O. NF-kappaB signalling in cerebral ischaemia. Biochem. Soc. Trans. 2006, 34:1291-1294.
25. Snider W.D., McMahon S.B. Tackling pain at the source: new ideas about nociceptors. Neuron 1998, 20:629-632.
26. Villa G., Fumagalli M., Verderio C., Abbracchio M.P., Ceruti S. Expression and contribution of satellite glial cells purinoceptors to pain transmission in sensory ganglia: an update. Neuron Glia Biol. 2010, 6:31-42.
27. Vinik A.I., Park T.S., Stansberry K.B., Pittenger G.L. Diabetic neuropathies. Diabetologia 2000, 43:957-973.
28. Vulchanova L., Olson T.H., Stone L.S., Riedl M.S., Elde R., Honda C.N. Cytotoxic targeting of isolectin IB4-binding sensory neurons. Neuroscience 2001, 108:143-155.
29. Wahl C., Liptay S., Adler G., Schmid R.M. Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B. J. Clin. Invest. 1998, 101:1163-1174.
30. Yang L., Tao L.Y., Chen X.P. Roles of NF-kappaB in central nervous system damage and repair. Neurosci. Bull. 2007, 23:307-313.
31. Zheng L., Howell S.J., Hatala D.A., Huang K., Kern T.S. Salicylate-based anti-inflammatory drugs inhibit the early lesion of diabetic retinopathy. Diabetes 2007, 56:337-345.
32. Zochodne D.W. Diabetic polyneuropathy: an update. Curr. Opin. Neurol. 2008, 21:527-533.