A novel approach for long-term oral drug administration in animal research

Journal of Neuroscience Methods

Volumn 195, Issue 2, 2011, Pages 194-199

  Overk, Cassia R ^a   Borgia, Jeffrey A ^a   Mufson, Elliott J ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Anastrozole; Hydration gel; Liquid chromatography mass spectrometry; Oral administration; Ovary; Pharmacology

Indexed keywords

ANASTROZOLE; DRINKING WATER; PLACEBO;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATMOSPHERIC PRESSURE; BODY WEIGHT; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG SOLUTION; FEMALE; GEL; HYDRATION; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOUSE; NONHUMAN; OVARY DISEASE; PALATABILITY; PRIORITY JOURNAL; QUALITY CONTROL; RANDOMIZED CONTROLLED TRIAL; TREATMENT DURATION;

ADMINISTRATION, ORAL; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMAL EXPERIMENTATION; ANIMALS; ANTIPSYCHOTIC AGENTS; BODY WEIGHT; CHROMATOGRAPHY, LIQUID; DISEASE MODELS, ANIMAL; FEMALE; GELS; HUMANS; MASS SPECTROMETRY; MICE; MICE, TRANSGENIC; NITRILES; PRESENILIN-1; REPRODUCIBILITY OF RESULTS; TAU PROTEINS; TRIAZOLES;

EID: 78751701381     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2010.12.009     Document Type: Article

References (20)

1. Balcombe J.P., Barnard N.D., Sandusky C. Laboratory routines cause animal stress. Contemp Top Lab Anim Sci 2004, 43:42-51.
2. Beaton E.A., deCatanzaro D. Novel males' capacity to disrupt early pregnancy in mice (Mus musculus) is attenuated via a chronic reduction of males' urinary 17beta-estradiol. Psychoneuroendocrinology 2005, 30:688-697.
3. Dupont S., Krust A., Gansmuller A., Dierich A., Chambon P., Mark M. Effect of single and compound knockouts of estrogen receptors alpha (ERalpha) and beta (ERbeta) on mouse reproductive phenotypes. Development 2000, 127:4277-4291.
4. Fatum M., Gyo Y., Diana P., Laufer N., Simon A. Is estradiol mandatory for an adequate follicular and embryo development? A mouse model using aromatase inhibitor (anastrozole). J Assist Reprod Genet 2006, 23:407-412.
5. Findlay J.W., Dillard R.F. Appropriate calibration curve fitting in ligand binding assays. AAPS J 2007, 9:E260-E267.
6. Fredenburg N., Engle T., Cooper D.M. Effects of alternate water sources on weight gain, blood chemistries, and food consumption in Sprague Dawley rats and ICR mice following ground transportation 2009, AALAS National Meeting, Dever, Colorado.
7. Gelfanova V., Higgs R.E., Dean R.A., Holtzman D.M., Farlow M.R., Siemers E.R., et al. Quantitative analysis of amyloid-beta peptides in cerebrospinal fluid using immunoprecipitation and MALDI-Tof mass spectrometry. Brief Funct Genomic Proteomic 2007, 6:149-158.
8. Goldman J.M., Murr A.S., Cooper R.L. The rodent estrous cycle: characterization of vaginal cytology and its utility in toxicological studies. Birth Defects Res B Dev Reprod Toxicol 2007, 80:84-97.
9. Howell A., Cuzick J., Baum M., Buzdar A., Dowsett M., Forbes J.F., et al. Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer. Lancet 2005, 365:60-62.
10. Kubatka P., Sadlonova V., Kajo K., Nosal'ova G., Ostatnikova D., Adamicova K. Chemopreventive effects of anastrozole in a premenopausal breast cancer model. Anticancer Res 2008, 28:2819-2823.
11. Mendes G.D., Hamamoto D., Ilha J., Pereira Ados S., De Nucci G. Anastrozole quantification in human plasma by high-performance liquid chromatography coupled to photospray tandem mass spectrometry applied to pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci 2007, 850:553-559.
12. Oddo S., Caccamo A., Shepherd J.D., Murphy M.P., Golde T.E., Kayed R., et al. Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron 2003, 39:409-421.
13. Oh K.-J., Perez S.E., Lagalwar S., Vana L., Binder L., Mufson E.J. Staging of Alzheimer's pathology in triple transgenic mice: a light and electron microscopic analysis. Int J Alzheimer Dis 2010, 2010:24.
14. Overk C.R., Kelley C.M., Mufson E.J. Brainstem Alzheimer's-like pathology in the triple transgenic mouse model of Alzheimer's disease. Neurobiol Dis 2009, 35:415-425.
15. Plourde P.V., Dyroff M., Dukes M. Arimidex: a potent and selective fourth-generation aromatase inhibitor. Breast Cancer Res Treat 1994, 30:103-111.
16. Sadlonova V., Kubatka P., Kajo K., Ostatnikova D., Nosalova G., Adamicova K., et al. Side effects of anastrozole in the experimental pre-menopausal mammary carcinogenesis. Neoplasma 2009, 56:124-129.
17. Sarkar K., Yang H. Encapsulation and extended release of anti-cancer anastrozole by stealth nanoparticles. Drug Deliv 2008, 15:343-346.
18. Turner K.J., Morley M., Atanassova N., Swanston I.D., Sharpe R.M. Effect of chronic administration of an aromatase inhibitor to adult male rats on pituitary and testicular function and fertility. J Endocrinol 2000, 164:225-238.
19. Vial J., Jardy A. Experimental comparison of the different approaches to estimate LOD and LOQ of an HPLC method. Anal Chem 1999, 71:2672-2677.
20. Yu J., He J., Zhang Y., Qin F., Xiong Z., Li F. An ultraperformance liquid chromatography-tandem mass spectrometry method for determination of anastrozole in human plasma and its application to a pharmacokinetic study. Biomed Chromatogr 2010, July 13 [Epub ahead of print].