QIP, a component of the vegetative RNA silencing pathway, is essential for meiosis and suppresses meiotic silencing in Neurospora crassa

Genetics

Volumn 186, Issue 1, 2010, Pages 127-133

  Lee, Dong Whan ^a   Millimaki, Ryan ^a   Aramayo, Rodolfo ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL PROTEIN; QUELLING DEFECTIVE 2 INTERACTING PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; FUNGAL GENE; GENE FUNCTION; GENE SILENCING; MEIOSIS; MOLECULAR BIOLOGY; NEUROSPORA CRASSA; NONHUMAN; PRIORITY JOURNAL;

CELL NUCLEUS; FUNGAL PROTEINS; MEIOSIS; NEUROSPORA CRASSA; PROTEIN TRANSPORT; RNA INTERFERENCE;

NEUROSPORA; NEUROSPORA CRASSA;

EID: 78751676211     PISSN: 00166731     EISSN: 00166731     Source Type: Journal    
DOI: 10.1534/genetics.110.118422     Document Type: Article

References (30)

1. ALEXANDER,W. G., N. B. RAJU, H. XIAO, T.M. HAMMOND, T.D. PERDUE et al., 2008 DCL-1 colocalizes with other components of the MSUD machinery and is required for silencing. Fungal Genet. Biol. 45: 719-727.
2. ARAMAYO, R., and R. L. METZENBERG, 1996 Meiotic transvection in fungi. Cell 86: 103-113.
3. ARAMAYO, R., and R. J. PRATT, 2010 Meiotic trans-sensing and silencing in Neurospora, pp. 132-144 in Cellular and Molecular Biology of Filamentous Fungi, edited by K. A. BORKOVICH and D. J. EBBOLE. ASM Press, Washington, DC.
4. +, a Neurospora crassa gene related to transcriptional regulators of fungal development. Genetics 144: 991-1003.
5. BARDIYA, N., W. G. ALEXANDER, T. D. PERDUE, E. G. BARRY, R. L. METZENBERG et al., 2008 Characterization of interactions between and among components of the meiotic silencing by unpaired DNA machinery in Neurospora crassa using bimolecular fluorescence complementation. Genetics 178: 593-596.
6. BORKOVICH, K. A., L. A. ALEX, O. YARDEN, M. FREITAG, G. E. TURNER et al., 2004 Lessons from the genome sequence of Neurospora crassa: tracing the path from genomic blueprint to multicellular organism. Microbiol. Mol. Biol. Rev. 68: 1-108.
7. CATALANOTTO, C., G. AZZALIN, G. MACINO and C. COGONI, 2000 Gene silencing in worms and fungi. Nature 404: 245.
8. COGONI, C., 2001 Homology-dependent gene silencing mechanisms in fungi. Annu. Rev. Microbiol. 55: 381-406.
9. COGONI, C., and G. MACINO, 1997 Isolation of quelling-defective (qde) mutants impaired in posttranscriptional transgene-induced gene silencing in Neurospora crassa. Proc. Natl. Acad. Sci. USA 94: 10233-10238.
10. COGONI, C., and G. MACINO, 1999a Gene silencing in Neurospora crassa requires a protein homologous to RNA-dependent RNA polymerase. Nature 399: 166-169. (Pubitemid 29230438)
11. COGONI, C., and G. MACINO, 1999b Posttranscriptional gene silencing in Neurospora by a RecQ DNA helicase. Science 286: 2342-2344.
12. COGONI, C., N. ROMANO and G. MACINO, 1994 Suppression of gene expression by homologous transgenes. Antonie Van Leeuwenhoek 65: 205-209.
13. COGONI, C., J. T. IRELAN, M. SCHUMACHER, T. J. SCHMIDHAUSER, E.U. SELKER et al., 1996 Transgene silencing of the al-1 gene in vegetative cells of Neurospora is mediated by a cytoplasmic effector and does not depend on DNA-DNA interactions or DNA methylation. EMBO J. 15: 3153-3163.
14. DAVIS, R. H., and F. J. DE SERRES, 1970 Genetic and microbiological research techniques for Neurospora crassa, pp. 79-143 in Metabolism of Amino Acids and Amines, edited by S. P. COLOWICK and N. O. KAPLAN. Academic Press, New York.
15. FREITAG, M., P. C. HICKEY, N. B. RAJU, E. U. SELKER and N. D. READ, 2004 GFP as a tool to analyze the organization, dynamics and function of nuclei and microtubules in Neurospora crassa. Fungal Genet. Biol. 41: 897-910.
16. GALAGAN, J. E., S. E. CALVO, K. A. BORKOVICH, E. U. SELKER, N. D.READ et al., 2003 The genome sequence of the filamentous fungus Neurospora crassa. Nature 422: 859-868.
17. HSIEH, J., and A. FIRE, 2000 Recognition and silencing of repeated DNA. Annu. Rev. Genet. 34: 187-204.
18. KUTIL, B. L., K. Y. SEONG and R. ARAMAYO, 2003 Unpaired genes do not silence their paired neighbors. Curr. Genet. 43: 425-432.
19. LEE, D. W., J. R. HAAG and R. ARAMAYO, 2003a Construction of strains for rapid homokaryon purification after integration of constructs at the histidine-3 (his-3) locus of Neurospora crassa. Curr. Genet. 43: 17-23.
20. LEE, D. W., R. J. PRATT, M. MCLAUGHLIN and R. ARAMAYO, 2003b An argonaute-like protein is required for meiotic silencing. Genetics 164: 821-828.
21. LEE, D. W., K.-Y. SEONG, R. J. PRATT, K. BAKER and R. ARAMAYO, 2004 Properties of unpaired DNA required for efficient silencing in Neurospora crassa. Genetics 167: 131-150.
22. MAITI, M., H. C. LEE and Y. LIU, 2007 QIP, a putative exonuclease, interacts with the Neurospora argonaute protein and facilitates conversion of duplex siRNA into single strands. Genes Dev. 21: 590-600.
23. MURPHY, R., and S. R. WENTE, 1996 An RNA-export mediator with an essential nuclear export signal. Nature 383: 357-360.
24. PAROO, Z., Q. LIU and X. WANG, 2007 Biochemical mechanisms of the RNA-induced silencing complex. Cell Res. 17: 187-194.
25. PRATT, R. J., and R. ARAMAYO, 2002 Improving the efficiency of gene replacements in Neurospora crassa: a first step towards a large-scale functional genomics project. Fungal Genet. Biol. 37: 56-71.
26. PRATT, R. J., D. W. LEE and R. ARAMAYO, 2004 DNA methylation affects meiotic trans-sensing, not meiotic silencing, in Neurospora. Genetics 168: 1925-1935.
27. RAJU, N. B., 1980 Meiosis and ascospore genesis in Neurospora. Eur. J. Cell Biol. 23: 208-223.
28. SHIU, P. K. T., B. N. RAJU, D. ZICKLER and R. METZENBERG, 2001 Meiotic silencing by unpaired DNA. Cell 107: 905-916.
29. SHIU, P. K. T., D. ZICKLER, N. B. RAJU, G. RUPRICH-ROBERT and R. L. METZENBERG, 2006 SAD-2 is required formeiotic silencing by unpaired DNA and perinuclear localization of SAD-1 RNA-directed RNA polymerase. Proc. Natl. Acad. Sci. USA 103: 2243-2248.
30. XIAO, H., W. G. ALEXANDER, T. M. HAMMOND, E. C. BOONE, T. D. PERDUE et al. 2010 QIP, a protein that converts duplex siRNA into single strands, is required for meiotic silencing by unpaired DNA. Genetics 186: 119-126.