Preserved serotonin transporter binding in de novo Parkinson's disease: Negative correlation with the dopamine transporter

Journal of Neurology

Volumn 258, Issue 1, 2011, Pages 19-26

  Strecker, Karl ^a,b   Wegner, Florian ^c   Hesse, Swen ^a   Becker, Georg Alexander ^a   Patt, Marianne ^a   Meyer, Philipp M ^a   Lobsien, Donald ^a   Schwarz, Johannes ^a   Sabri, Osama ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b NRZ Bennewitz   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Dopamine transporter; Parkinson's disease; PET; Positron emission tomography; Serotonin transporter

Indexed keywords

DOPAMINE TRANSPORTER; SEROTONIN TRANSPORTER;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; CORRELATION ANALYSIS; DEPRESSION; FEMALE; HUMAN; MALE; MESENCEPHALON; NUCLEAR MAGNETIC RESONANCE IMAGING; PARKINSON DISEASE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN BINDING; RATING SCALE; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

ADULT; AGE OF ONSET; AGED; BRAIN CHEMISTRY; DEPRESSION; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; PARKINSON DISEASE; POSITRON-EMISSION TOMOGRAPHY; PROTEIN BINDING; PSYCHIATRIC STATUS RATING SCALES; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS;

EID: 78751647729     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-010-5666-5     Document Type: Article

References (34)

1. RL Albin RA Koeppe NI Bohnen K Wernette MA Kilbourn KA Frey 2008 Spared caudal brainstem SERT binding in early Parkinson's disease J Cereb Blood Flow Metab 28 441 444 1:CAS:528:DC%2BD1cXisVKgs70%3D 10.1038/sj.jcbfm.9600599 18073772 (Pubitemid 351304276)
2. 11C]DASB Mov Disord 23 1776 1780 10.1002/mds.22212 18661545
3. H Braak K Del Tredici 2008 Invited article: nervous system pathology in sporadic Parkinson disease Neurology 70 1916 1925 10.1212/01.wnl.0000312279. 49272.9f 18474848 (Pubitemid 351684646)
4. T Brucke P Riederer 1986 Neurobiologic and pharmacologic studies on the pathogenesis of Parkinson disease Wien Med Wochenschr 136 401 408 1:STN:280:DyaL2s%2FntFyrug%3D%3D 2878540
5. 123I]β-CIT SPECT study J Neural Transm 115 721 729 1:CAS:528:DC%2BD1cXmslyhur4%3D 10.1007/s00702-007-0015-2 18335163
6. M Carta T Carlsson D Kirik A Bjorklund 2007 Dopamine released from 5-HT terminals is the cause of L-DOPA-induced dyskinesia in parkinsonian rats Brain 130 1819 1833 10.1093/brain/awm082 17452372 (Pubitemid 47343795)
7. LM de Lau MM Breteler 2006 Epidemiology of Parkinson's disease Lancet Neurol 5 525 535 10.1016/S1474-4422(06)70471-9 16713924 (Pubitemid 44262284)
8. P Gaspar A Febvret J Colombo 1993 Serotonergic sprouting in primate MTP-induced hemiparkinsonism Exp Brain Res 96 100 106 1:CAS:528: DyaK2cXhs1Slt7c%3D 7902292
9. M Guttman I Boileau J Warsh JA Saint-Cyr N Ginovart T McCluskey S Houle A Wilson E Mundo P Rusjan J Meyer SJ Kish 2007 Brain serotonin transporter binding in non-depressed patients with Parkinson's disease Eur J Neurol 14 523 528 1:STN:280:DC%2BD2s3ivFShsg%3D%3D 10.1111/j.1468-1331.2007.01727.x 17437611 (Pubitemid 46587839)
10. GM Halliday PC Blumbergs RG Cotton WW Blessing LB Geffen 1990 Loss of brainstem serotonin- and substance P-containing neurons in Parkinson's disease Brain Res 510 104 107 1:STN:280:DyaK3c3htlWrtQ%3D%3D 10.1016/0006-8993(90)90733- R 1691042 (Pubitemid 20060808)
11. MA Hely JG Morris WG Reid R Trafficante 2005 Sydney Multicenter Study of Parkinson's disease: non-l-dopa-responsive problems dominate at 15 years Mov Disord 20 190 199 10.1002/mds.20324 15551331 (Pubitemid 40361122)
12. JG Hensler RC Ferry DM Labow GB Kovachich A Frazer 1994 Quantitative autoradiography of the serotonin transporter to assess the distribution of serotonergic projections from the dorsal raphe nucleus Synapse 17 1 15 1:STN:280:DyaK2czhslWjtQ%3D%3D 10.1002/syn.890170102 8042142
13. S Hesse C Oehlwein H Barthel J Schwarz D Polster A Wagner O Sabri 2006 Possible impact of dopamine SPECT on decision-making for drug treatment in Parkinsonian syndrome J Neural Transm 113 1177 1190 1:CAS:528: DC%2BD28Xosleqsbo%3D 10.1007/s00702-005-0401-6 16463120 (Pubitemid 44291013)
14. S Hesse K Strecker D Winkler J Luthardt C Scherfler A Reupert C Oehlwein H Barthel JP Schneider F Wegner P Meyer J Meixensberger O Sabri J Schwarz 2008 Effects of subthalamic nucleus stimulation on striatal dopaminergic transmission in patients with Parkinson's disease within one-year follow-up J Neurol 255 1059 1066 10.1007/s00415-008-0849-z 18446306
15. AJ Hughes SE Daniel L Kilford AJ Lees 1992 Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases J Neurol Neurosurg Psychiatry 55 181 184 1:STN:280:DyaK383is1Omsg%3D%3D 10.1136/jnnp.55.3.181 1564476
16. 11C]DASB positron emission tomography studies of the serotonin transporter in human brain J Cereb Blood Flow Metab 23 1096 1112 10.1097/01.WCB.0000085441.37552.CA 12973026
17. RB Innis VJ Cunningham J Delforge M Fujita A Gjedde RN Gunn J Holden S Houle SC Huang M Ichise H Iida H Ito Y Kimura RA Koeppe GM Knudsen J Knuuti AA Lammertsma M Laruelle J Logan RP Maguire MA Mintun ED Morris R Parsey JC Price M Slifstein V Sossi T Suhara JR Votaw DF Wong RE Carson 2007 Consensus nomenclature for in vivo imaging of reversibly binding radioligands J Cereb Blood Flow Metab 27 1533 1539 1:CAS:528:DC%2BD2sXptlSqtrc%3D 10.1038/sj.jcbfm.9600493 17519979 (Pubitemid 47301451)
18. BL Jacobs EC Azmitia 1992 Structure and function of the brain serotonin system Physiol Rev 72 165 229 1:CAS:528:DyaK38XhsVCjs7Y%3D 1731370
19. L Kerenyi GA Ricaurte DJ Schretlen U McCann J Varga WB Mathews HT Ravert RF Dannals J Hilton DF Wong Z Szabo 2003 Positron emission tomography of striatal serotonin transporters in Parkinson disease Arch Neurol 60 1223 1229 10.1001/archneur.60.9.1223 12975287 (Pubitemid 37099627)
20. SJ Kish J Tong O Hornykiewicz A Rajput LJ Chang M Guttman Y Furukawa 2008 Preferential loss of serotonin markers in caudate versus putamen in Parkinson's disease Brain 131 120 131 17956909
21. GG Kovacs S Kloppel I Fischer S Dorner E Lindeck-Pozza P Birner IC Botefur P Pilz B Volk H Budka 2003 Nucleus-specific alteration of raphe neurons in human neurodegenerative disorders Neuroreport 14 73 76 1:CAS:528: DC%2BD3sXmsVShsw%3D%3D 10.1097/00001756-200301200-00014 12544834 (Pubitemid 36160745)
22. AF Leentjens FR Verhey GJ Luijckx J Troost 2000 The validity of the Beck Depression Inventory as a screening and diagnostic instrument for depression in patients with Parkinson's disease Mov Disord 15 1221 1224 1:STN:280: DC%2BD3MzgsVahuw%3D%3D 10.1002/1531-8257(200011)15:6<1221::AID-MDS1024>3. 0.CO;2-H 11104209
23. Mai JK, Paxinos G, Assheuer JK (2004) Atlas of the human brain, 2nd edn. Elsevier Academic Press, San Diego
24. 123I]β-CIT/SPECT imaging demonstrates bilateral loss of dopamine transporters in hemi-Parkinson's disease Neurology 46 231 237 1:STN:280:DyaK287ktlWqtg%3D%3D 8559382
25. R Mayeux 1990 The "serotonin hypothesis" for depression in Parkinson's disease Adv Neurol 53 163 166 1:STN:280:DyaK3M%2FltVymtw%3D%3D 2239456
26. JH Meyer S Houle S Sagrati A Carella DF Hussey N Ginovart V Goulding J Kennedy AA Wilson 2004 Brain serotonin transporter binding potential measured with carbon 11-labeled DASB positron emission tomography: effects of major depressive episodes and severity of dysfunctional attitudes Arch Gen Psychiatry 61 1271 1279 1:CAS:528:DC%2BD2MXjt1Kmtw%3D%3D 10.1001/archpsyc.61.12.1271 15583118 (Pubitemid 39602843)
27. PM Meyer K Strecker K Kendziorra G Becker S Hesse D Woelpl A Hensel M Patt D Sorger F Wegner D Lobsien H Barthel P Brust HJ Gertz O Sabri J Schwarz 2009 Reduced alpha4beta2-nicotinic acetylcholine receptor binding and its relationship to mild cognitive and depressive symptoms in Parkinson disease Arch Gen Psychiatry 66 866 877 1:CAS:528:DC%2BD1MXhtVyhurrP 10.1001/ archgenpsychiatry.2009.106 19652126
28. S Mounayar S Boulet D Tande C Jan M Pessiglione EC Hirsch J Feger M Savasta C Francois L Tremblay 2007 A new model to study compensatory mechanisms in MPTP-treated monkeys exhibiting recovery Brain 130 2898 2914 10.1093/brain/awm208 17855373 (Pubitemid 350033961)
29. P Naarding AF Leentjens F van Kooten FR Verhey 2002 Disease-specific properties of the rating scale for depression in patients with stroke, Alzheimer's dementia, and Parkinson's disease J Neuropsychiatry Clin Neurosci 14 329 334 12154158
30. SS O'Sullivan DR Williams DA Gallagher LA Massey L Silveira-Moriyama AJ Lees 2008 Nonmotor symptoms as presenting complaints in Parkinson's disease: a clinicopathological study Mov Disord 23 101 106 10.1002/mds.21813 17994582 (Pubitemid 351281225)
31. RV Parsey RS Hastings MA Oquendo YY Huang N Simpson J Arcement Y Huang RT Ogden RL Van Heertum V Arango JJ Mann 2006 Lower serotonin transporter binding potential in the human brain during major depressive episodes Am J Psychiatry 163 52 58 10.1176/appi.ajp.163.1.52 16390889 (Pubitemid 43050103)
32. W Paulus K Jellinger 1991 The neuropathologic basis of different clinical subgroups of Parkinson's disease J Neuropathol Exp Neurol 50 743 755 1:STN:280:DyaK38%2FosFWjsQ%3D%3D 10.1097/00005072-199111000-00006 1748881
33. W Poewe 2008 Non-motor symptoms in Parkinson's disease Eur J Neurol 15 Suppl 1 14 20 10.1111/j.1468-1331.2008.02056.x 18353132 (Pubitemid 351421304)
34. M Sawada T Nagatsu I Nagatsu K Ito R Iizuka T Kondo H Narabayashi 1985 Tryptophan hydroxylase activity in the brains of controls and parkinsonian patients J Neural Transm 62 107 115 1:STN:280:DyaL2M3mtlKnsw%3D%3D 10.1007/BF01260420 4020380