Morphological features in children with autism spectrum disorders: A matched case-control study

Journal of Autism and Developmental Disorders

Volumn 41, Issue 1, 2011, Pages 23-31

  Ozgen, Heval ^a,b   Hellemann, Gerhard S ^c   Stellato, Rebecca K ^d   Lahuis, Bertine ^a,b   Van Daalen, Emma ^a,b   Staal, Wouter G ^a,b   Rozendal, Marije ^a,b   Hennekam, Raoul C ^e,f   Beemer, Frits A ^a   Van Engeland, Herman ^a,b  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c UTRECHT UNIVERSITY   (Netherlands)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e EMMA CHILDREN S HOSPITAL   (Netherlands)

^f UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Biological marker; Common variants; Dysmorphology; Etiology; Heterogeneity; Minor anomalies

Indexed keywords

ADOLESCENT; ADULT; ANTHROPOMETRIC PARAMETERS; ANTHROPOMETRY; ARTICLE; AUTISM; CASE CONTROL STUDY; CHILD; CLINODACTYLY; CONTROLLED STUDY; CRANIOFACIAL MALFORMATION; DRY SKIN; EAR MALFORMATION; FEMALE; FLATFOOT; HALLUX VALGUS; HUMAN; LIP MALFORMATION; MAJOR CLINICAL STUDY; MALE; MALFORMATION SYNDROME; MOUTH MALFORMATION; NOSE MALFORMATION; PRESCHOOL CHILD; PREVALENCE; PRIORITY JOURNAL; TOOTH MALFORMATION;

ABNORMALITIES, MULTIPLE; ADOLESCENT; AUTISTIC DISORDER; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; FEMALE; FINGERS; FOOT DEFORMITIES, CONGENITAL; HAND DEFORMITIES, CONGENITAL; HEAD; HUMANS; MALE; ODDS RATIO; REGRESSION ANALYSIS;

EID: 78751644105     PISSN: 01623257     EISSN: 15733432     Source Type: Journal    
DOI: 10.1007/s10803-010-1018-7     Document Type: Article

References (44)

1. Aase, J. M. (1990). Diagnostic dysmorphology. New York: Plenum Medical Book Co.
2. BS Abrahams DH Geschwind 2008 Advances in autism genetics: On the threshold of a new neurobiology Nature Reviews Genetics 9 5 341 355 10.1038/nrg2346 18414403 (Pubitemid 351556064)
3. VH Akabaliev ST Sivkov 2007 Internal consistency of Waldrop physical anomaly scale in schizophrenic patients Psychiatry Research 150 1 81 88 10.1016/j.psychres.2003.02.002 17276516 (Pubitemid 46281333)
4. American Psychiatric Association, American Psychiatric Association, & Task Force on DSM-IV. (2000). Diagnostic and statistical manual of mental disorders: DSM-IV-TR (4th ed.). Washington, DC: American Psychiatric Association.
5. A Bailey A Le Couteur I Gottesman P Bolton E Simonoff E Yuzda, et al. 1995 Autism as a strongly genetic disorder: Evidence from a British twin study Psychological Medicine 25 1 63 77 10.1017/S0033291700028099 7792363
6. S Baron-Cohen RC Knickmeyer MK Belmonte 2005 Sex differences in the brain: implications for explaining autism Science 310 5749 819 823 10.1126/science.1115455 16272115 (Pubitemid 41567334)
7. M Campbell B Geller AM Small TA Petti SH Ferris 1978 Minor physical anomalies in young psychotic children American Journal of Psychiatry 135 5 573 575 645950
8. Cluitmans, T. L. M., Hooi, J. D., Nijbroek, W., & Oosterlee, A. (2002). Gezondheidsprofiel Kennemerland; G.G.D. Kennemerland: Haarlem/Heemskerk.
9. J Cohen 1960 A coefficient of agreement for nominal scales Educational and Psychological Measurement 20 37 46 10.1177/001316446002000104
10. M Conciatori CJ Stodgell SL Hyman M O'Bara R Militerni C Bravaccio, et al. 2004 Association between the HOXA1 A218G polymorphism and increased head circumference in patients with autism Biological Psychiatry 55 4 413 419 10.1016/j.biopsych.2003.10.005 14960295 (Pubitemid 38199992)
11. H Engels A Brockschmidt A Hoischen C Landwehr K Bosse C Walldorf, et al. 2007 DNA microarray analysis identifies candidate regions and genes in unexplained mental retardation Neurology 68 10 743 750 10.1212/01.wnl. 0000256367.70365.e0 17339581 (Pubitemid 46667899)
12. DH Geschwind P Levitt 2007 Autism spectrum disorders: developmental disconnection syndromes Current Opinion in Neurobiology 17 1 103 111 10.1016/j.conb.2007.01.009 17275283 (Pubitemid 46237744)
13. CT Gualtieri A Adams CD Shen D Loiselle 1982 Minor physical anomalies in alcoholic and schizophrenic adults and hyperactive and autistic children American Journal of Psychiatry 139 5 640 643 7072852
14. Hall, J. G., & Hall, J. G. (2007). Handbook of physical measurements (2nd ed.). Oxford; New York: Oxford University Press.
15. P Hammond C Forster-Gibson AE Chudley JE Allanson TJ Hutton SA Farrell, et al. 2008 Face-brain asymmetry in autism spectrum disorders Molecular Psychiatry 13 6 614 623 10.1038/mp.2008.18 18317467 (Pubitemid 351704940)
16. AY Hardan MS Keshavan S Sreedhar M Vemulapalli NJ Minshew 2006 An MRI study of minor physical anomalies in autism Journal of Autism and Developmental Disorders 36 5 607 611 10.1007/s10803-006-0103-4 16609827 (Pubitemid 44336983)
17. S Holm 1979 A simple sequentially rejective multiple test procedure Scandinavian Journal of Statistics 6 65 70
18. B Ismail E Cantor-Graae TF McNeil 1998 Minor physical anomalies in schizophrenic patients and their siblings American Journal of Psychiatry 155 12 1695 1702 9842778 (Pubitemid 28547493)
19. A Lane A Kinsella P Murphy M Byrne J Keenan K Colgan, et al. 1997 The anthropometric assessment of dysmorphic features in schizophrenia as an index of its developmental origins Psychological Medicine 27 5 1155 1164 10.1017/S0033291797005503 9300519 (Pubitemid 27401837)
20. C Lord M Rutter A Le Couteur 1994 Autism diagnostic interview-revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders Journal of Autism and Developmental Disorders 24 5 659 685 10.1007/BF02172145 7814313 (Pubitemid 24309810)
21. J McGrath O El-Saadi V Grim S Cardy B Chapple D Chant, et al. 2002 Minor physical anomalies and quantitative measures of the head and face in patients with psychosis Archives of General Psychiatry 59 5 458 464 10.1001/archpsyc.59. 5.458 11982450
22. JJ McGrath J van Os C Hoyos PB Jones I Harvey RM Murray 1995 Minor physical anomalies in psychoses: associations with clinical and putative aetiological variables Schizophrenia Research 18 1 9 20 10.1016/0920-9964(95) 00016-X 8929756
23. NJ Mendelsohn GB Schaefer 2008 Genetic evaluation of autism Seminars in Pediatric Neurology 15 1 27 31 10.1016/j.spen.2008.01.005 18342258 (Pubitemid 351374839)
24. JH Merks HM Ozgen TL Cluitmans JM van der Burg-van Rijn JM Cobben FE van Leeuwen, et al. 2006 Normal values for morphological abnormalities in school children American Journal of Medical Genetics Part A 140 19 2091 2109 10.1002/ajmg.a.31355 16838341 (Pubitemid 44522457)
25. JH Merks HM Ozgen J Koster AH Zwinderman HN Caron RC Hennekam 2008 Prevalence and patterns of morphological abnormalities in patients with childhood cancer JAMA 299 1 61 69 10.1001/jama.2007.66 18167407
26. JH Merks CD van Karnebeek HN Caron RC Hennekam 2003 Phenotypic abnormalities: terminology and classification American Journal of Medical Genetics Part A 123 3 211 230
27. JH Miles LL Hadden TN Takahashi RE Hillman 2000 Head circumference is an independent clinical finding associated with autism American Journal of Medical Genetics 95 4 339 350 10.1002/1096-8628(20001211)95:4<339::AID-AJMG9>3.0. CO;2-B 11186888
28. JH Miles TN Takahashi J Hong N Munden N Flournoy SR Braddock, et al. 2008 Development and validation of a measure of dysmorphology: Useful for autism subgroup classification American Journal of Medical Genetics Part A 146A 9 1101 1116 10.1002/ajmg.a.32244 18383511 (Pubitemid 351628596)
29. R Mizuno 2000 The male/female ratio of fetal deaths and births in Japan Lancet 356 9231 738 739 10.1016/S0140-6736(00)02637-4 11085698
30. SE Mouridsen B Rich T Isager 2008 Psychiatric disorders in adults diagnosed as children with atypical autism: A case control study Journal of Neural Transmission 115 1 135 138 10.1007/s00702-007-0798-1 17768593
31. LA Muscarella V Guarnieri R Sacco R Militerni C Bravaccio S Trillo, et al. 2007 HOXA1 gene variants influence head growth rates in humans American Journal of Medical Genetics Part B Neuropsychiatric Genetics 144B 3 388 390 10.1002/ajmg.b.30469 (Pubitemid 46642035)
32. HM Ozgen JW Hop JJ Hox FA Beemer H van Engeland 2010 Minor physical anomalies in autism: A meta-analysis Molecular Psychiatry 5 3 300 307 10.1038/mp.2008.75
33. AD Rasalam H Hailey JH Williams SJ Moore PD Turnpenny DJ Lloyd, et al. 2005 Characteristics of fetal anticonvulsant syndrome associated autistic disorder Developmental Medicine and Child Neurology 47 8 551 555 10.1017/S0012162205001076 16108456 (Pubitemid 41131614)
34. PM Rodier SE Bryson JP Welch 1997 Minor malformations and physical measurements in autism: Data from Nova Scotia Teratology 55 5 319 325 10.1002/(SICI)1096-9926(199705)55:5<319::AID-TERA4>3.0.CO;2-U 9261926 (Pubitemid 27389922)
35. R Sacco R Militerni A Frolli C Bravaccio A Gritti M Elia, et al. 2007 Clinical, morphological, and biochemical correlates of head circumference in autism Biological Psychiatry 62 9 1038 1047 10.1016/j.biopsych.2007.04.039 17644070 (Pubitemid 47562373)
36. J Sebat B Lakshmi D Malhotra J Troge C Lese-Martin T Walsh, et al. 2007 Strong association of de novo copy number mutations with autism Science 316 5823 445 449 10.1126/science.1138659 17363630 (Pubitemid 46651493)
37. DW Smith KE Bostian 1964 Congenital anomalies associated with idiopathic mental retardation Journal of Pediatrics 65 189 196 10.1016/S0022-3476(64)80519- 9 14198408
38. JP Steg JL Rapoport 1975 Minor physical anomalies in normal, neurotic, learning disabled, and severely disturbed children Journal of Autism and Childhood Schizophrenia 5 4 299 307 10.1007/BF01540677 1243135
39. P Szatmari AD Paterson L Zwaigenbaum W Roberts J Brian XQ Liu, et al. 2007 Mapping autism risk loci using genetic linkage and chromosomal rearrangements Nature Genetics 39 3 319 328 10.1038/ng1985 17322880 (Pubitemid 46328498)
40. S van Buuren 2004 Body-mass index cut-off values for underweight in Dutch children Ned Tijdschr Geneeskd 148 40 1967 1972 15524132
41. van Lier, A. (2004). Sterfte in Noord-Holland en Flevoland. Analyse van sterftecijfers in de provincies Noord-Holland en Flevoland 1996-2002-regio Kennemerland. Haarlem: G.G.D. Noord- Holland en Flevoland.
42. MF Waldrop FA Pedersen RQ Bell 1968 Minor physical anomalies and behavior in preschool children Child Development 39 2 391 400 10.2307/1126953 4172079
43. HA Walker 1977 Incidence of minor physical anomaly in autism Journal of Autism and Childhood Schizophrenia 7 2 165 176 10.1007/BF01537727 194879
44. SM Weinberg EA Jenkins ML Marazita BS Maher 2007 Minor physical anomalies in schizophrenia: A meta-analysis Schizophrenia Research 89 1-3 72 85 10.1016/j.schres.2006.09.002 17079117 (Pubitemid 44881305)