메뉴 건너뛰기




Volumn 87, Issue 1, 2011, Pages 9-16

Treatment of syphilis in HIV-infected subjects: A systematic review of the literature

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; ANTIINFECTIVE AGENT; AZITHROMYCIN; BENETHAMINE PENICILLIN; BENZATHINE PENICILLIN; CEFTRIAXONE; DOXYCYCLINE; ERYTHROMYCIN; PENICILLIN G; PROBENECID; PROCAINE PENICILLIN; TETRACYCLINE;

EID: 78751642638     PISSN: 13684973     EISSN: None     Source Type: Journal    
DOI: 10.1136/sti.2010.043893     Document Type: Review
Times cited : (54)

References (47)
  • 1
    • 0015446167 scopus 로고
    • Penicillin in the treatment of syphilis. The experience of three decades
    • Idsoe O, Guthe T, Willcox RR. Penicillin in the treatment of syphilis. The experience of three decades. Bull World Health Organ 1972;47:1-68.
    • (1972) Bull World Health Organ , vol.47 , pp. 1-68
    • Idsoe, O.1    Guthe, T.2    Willcox, R.R.3
  • 2
    • 33746774864 scopus 로고    scopus 로고
    • Sexually transmitted diseases treatment guidelines, 2006
    • Centers for Disease Control and Prevention
    • Workowski KA, Berman SM; Centers for Disease Control and Prevention. Sexually transmitted diseases treatment guidelines, 2006. MMWR Recomm Rep 2006;55(RR-11):1-94.
    • (2006) MMWR Recomm Rep , vol.55 , Issue.RR-11 , pp. 1-94
    • Workowski, K.A.1    Berman, S.M.2
  • 3
    • 0024261122 scopus 로고
    • Invasion of the central nervous system by Treponema pallidum: Implications for diagnosis and treatment
    • Lukehart SA, Hook EW 3rd, Baker-Zander SA, et al. Invasion of the central nervous system by Treponema pallidum: implications for diagnosis and treatment. Ann Intern Med 1988;109:855-62.
    • (1988) Ann Intern Med , vol.109 , pp. 855-862
    • Lukehart, S.A.1    Hook III, E.W.2    Baker-Zander, S.A.3
  • 4
    • 10744224897 scopus 로고    scopus 로고
    • Cerebrospinal fluid abnormalities in patients with syphilis: Association with clinical and laboratory features
    • Marra CM, Maxwell CL, Smith SL, et al. Cerebrospinal fluid abnormalities in patients with syphilis: association with clinical and laboratory features. J Infect Dis 2004;189:369-76.
    • (2004) J Infect Dis , vol.189 , pp. 369-376
    • Marra, C.M.1    Maxwell, C.L.2    Smith, S.L.3
  • 5
    • 0018746959 scopus 로고
    • Penicillin levels in blood and CSF achieved by treatment of syphilis
    • Dunlop EM, Al-Egaily SS, Houang ET. Penicillin levels in blood and CSF achieved by treatment of syphilis. JAMA 1979;241:2538-40.
    • (1979) JAMA , vol.241 , pp. 2538-2540
    • Dunlop, E.M.1    Al-Egaily, S.S.2    Houang, E.T.3
  • 6
    • 0019851144 scopus 로고
    • The profile of neurosyphilis in Denmark: A clinical and serological study of all patients in Denmark with neurosyphilis disclosed in the years 19711979 incl. by Wassermann reaction (CWRM) in the cerebrospinal fluid
    • Perdrup A, Jorgensen BB, Pedersen NS. The profile of neurosyphilis in Denmark: A clinical and serological study of all patients in Denmark with neurosyphilis disclosed in the years 1971-1979 incl. by Wassermann reaction (CWRM) in the cerebrospinal fluid. Acta Derm Venereol 1981;96:1-14.
    • (1981) Acta Derm Venereol , vol.96 , pp. 1-14
    • Perdrup, A.1    Jorgensen, B.B.2    Pedersen, N.S.3
  • 7
    • 0023202640 scopus 로고
    • Neurologic relapse after benzathine penicillin therapy for secondary syphilis in a patient with HIV infection
    • Berry CD, Hooton TM, Collier AC, et al. Neurologic relapse after benzathine penicillin therapy for secondary syphilis in a patient with HIV infection. N Engl J Med 1987;316:1587-9.
    • (1987) N Engl J Med , vol.316 , pp. 1587-1589
    • Berry, C.D.1    Hooton, T.M.2    Collier, A.C.3
  • 8
    • 34247240553 scopus 로고    scopus 로고
    • Syphilis and HIV infection: An update
    • Zetola NM, Klausner JD. Syphilis and HIV infection: an update. Clin Infect Dis 2007;44:1222-8.
    • (2007) Clin Infect Dis , vol.44 , pp. 1222-1228
    • Zetola, N.M.1    Klausner, J.D.2
  • 9
    • 0029914622 scopus 로고    scopus 로고
    • Assessing the quality of reports of randomized clinical trials: Is blinding necessary?
    • Jadad AR, Moore RA, Carroll D, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 1996;17:1-12.
    • (1996) Control Clin Trials , vol.17 , pp. 1-12
    • Jadad, A.R.1    Moore, R.A.2    Carroll, D.3
  • 10
    • 0026496093 scopus 로고
    • Response of latent syphilis or neurosyphilis to ceftriaxone therapy in persons infected with human immunodeficiency virus
    • Dowell ME, Ross PG, Musher DM, et al. Response of latent syphilis or neurosyphilis to ceftriaxone therapy in persons infected with human immunodeficiency virus. Am J Med 1992;93:481-8.
    • (1992) Am J Med , vol.93 , pp. 481-488
    • Dowell, M.E.1    Ross, P.G.2    Musher, D.M.3
  • 11
    • 0027477416 scopus 로고
    • Effects of HIV infection on the serologic manifestations and response to treatment of syphilis in intravenous drug users
    • Gourevitch MN, Selwyn PA, Davenny K, et al. Effects of HIV infection on the serologic manifestations and response to treatment of syphilis in intravenous drug users. Ann Intern Med 1993;118:350-5.
    • (1993) Ann Intern Med , vol.118 , pp. 350-355
    • Gourevitch, M.N.1    Selwyn, P.A.2    Davenny, K.3
  • 12
    • 0027990614 scopus 로고
    • Syphilis precoce et infection par le VIH: A propos de 13 cas
    • Caumes E, Minta D, Niel G, et al. Syphilis precoce et infection par le VIH: A propos de 13 cas. Med Mal Infect 1994;24:785-91.
    • (1994) Med Mal Infect , vol.24 , pp. 785-791
    • Caumes, E.1    Minta, D.2    Niel, G.3
  • 14
    • 0028200012 scopus 로고
    • Altered clinical presentation of early syphilis in patients with human immunodeficiency virus infection
    • Hutchinson CM, Hook EW 3rd, Shepherd M, et al. Altered clinical presentation of early syphilis in patients with human immunodeficiency virus infection. Ann Intern Med 1994;121:94-100.
    • (1994) Ann Intern Med , vol.121 , pp. 94-100
    • Hutchinson, C.M.1    Hook III, E.W.2    Shepherd, M.3
  • 15
    • 0029166323 scopus 로고
    • Similar serological response to conventional therapy for syphilis among HIV-positive and HIV-negative women
    • Goeman J, Kivuvu M, Nzila N, et al. Similar serological response to conventional therapy for syphilis among HIV-positive and HIV-negative women. Genitourin Med 1995;71:275-9.
    • (1995) Genitourin Med , vol.71 , pp. 275-279
    • Goeman, J.1    Kivuvu, M.2    Nzila, N.3
  • 16
    • 0029031049 scopus 로고
    • Syphilis and neurosyphilis in a human immunodeficiency virus type-1 seropositive population: Evidence for frequent serologic relapse after therapy
    • Malone JL, Wallace MR, Hendrick BB, et al. Syphilis and neurosyphilis in a human immunodeficiency virus type-1 seropositive population: Evidence for frequent serologic relapse after therapy. Am J Med 1995;99:55-63.
    • (1995) Am J Med , vol.99 , pp. 55-63
    • Malone, J.L.1    Wallace, M.R.2    Hendrick, B.B.3
  • 17
    • 0029973413 scopus 로고    scopus 로고
    • Resolution of serum and cerebrospinal fluid abnormalities after treatment of neurosyphilis. Influence of concomitant human immunodeficiency virus infection
    • Marra CM, Longstreth WT Jr, Maxwell CL, et al. Resolution of serum and cerebrospinal fluid abnormalities after treatment of neurosyphilis. Influence of concomitant human immunodeficiency virus infection. Sex Transm Dis 1996;23:184-9.
    • (1996) Sex Transm Dis , vol.23 , pp. 184-189
    • Marra, C.M.1    Longstreth Jr., W.T.2    Maxwell, C.L.3
  • 18
    • 0030064255 scopus 로고    scopus 로고
    • Serologic response to treatment of syphilis in patients with HIV infection
    • Yinnon AM, Coury-Doniger P, Polito R, et al. Serologic response to treatment of syphilis in patients with HIV infection. Arch Intern Med 1996;156:321-5.
    • (1996) Arch Intern Med , vol.156 , pp. 321-325
    • Yinnon, A.M.1    Coury-Doniger, P.2    Polito, R.3
  • 19
    • 8544252402 scopus 로고    scopus 로고
    • A randomized trial of enhanced therapy for early syphilis in patients with and without human immunodeficiency virus infection
    • The Syphilis and HIV Study Group
    • Rolfs RT, Joesoef MR, Hendershot EF, et al. A randomized trial of enhanced therapy for early syphilis in patients with and without human immunodeficiency virus infection. The Syphilis and HIV Study Group. N Engl J Med 1997;337:307-14.
    • (1997) N Engl J Med , vol.337 , pp. 307-314
    • Rolfs, R.T.1    Joesoef, M.R.2    Hendershot, E.F.3
  • 20
    • 0032751493 scopus 로고    scopus 로고
    • Response to standard syphilis treatment in patients infected with the human immunodeficiency virus
    • Bordon J, Martinez-Vazquez C, de la Fuente-Aguado J, et al. Response to standard syphilis treatment in patients infected with the human immunodeficiency virus. Eur J Clin Microbiol Infect Dis 1999;18:729-32.
    • (1999) Eur J Clin Microbiol Infect Dis , vol.18 , pp. 729-732
    • Bordon, J.1    Martinez-Vazquez, C.2    De La Fuente-Aguado, J.3
  • 21
    • 0036330679 scopus 로고    scopus 로고
    • A randomized, comparative pilot study of azithromycin versus benzathine penicillin G for treatment of early syphilis
    • Hook EW 3rd, Martin DH, Stephens J, et al. A randomized, comparative pilot study of azithromycin versus benzathine penicillin G for treatment of early syphilis. Sex Transm Dis 2002;29:486-90.
    • (2002) Sex Transm Dis , vol.29 , pp. 486-490
    • Hook III, E.W.1    Martin, D.H.2    Stephens, J.3
  • 23
    • 2442614762 scopus 로고    scopus 로고
    • Response of HIV-infected patients with asymptomatic syphilis to intensive intramuscular therapy with ceftriaxone or procaine penicillin
    • Smith NH, Musher DM, Huang DB, et al. Response of HIV-infected patients with asymptomatic syphilis to intensive intramuscular therapy with ceftriaxone or procaine penicillin. Int J STD AIDS 2004;15:328-32.
    • (2004) Int J STD AIDS , vol.15 , pp. 328-332
    • Smith, N.H.1    Musher, D.M.2    Huang, D.B.3
  • 24
    • 21444435166 scopus 로고    scopus 로고
    • Clinical characteristics and evolution of syphilis in 24 HIV+ individuals in Rio de Janeiro, Brazil
    • Gutierrez-Galhardo MC, do Valle GF, Sa FC, et al. Clinical characteristics and evolution of syphilis in 24 HIV+ individuals in Rio de Janeiro, Brazil. Rev Inst Med Trop Sao Paulo 2005;47:153-7.
    • (2005) Rev Inst Med Trop Sao Paulo , vol.47 , pp. 153-157
    • Gutierrez-Galhardo, M.C.1    Do Valle, G.F.2    Sa, F.C.3
  • 25
    • 19944429311 scopus 로고    scopus 로고
    • Effectiveness of syphilis treatment using azithromycin and/or benzathine penicillin in Rakai, Uganda
    • Kiddugavu MG, Kiwanuka N, Wawer MJ, et al. Effectiveness of syphilis treatment using azithromycin and/or benzathine penicillin in Rakai, Uganda. Sex Transm Dis 2005;32:1-6.
    • (2005) Sex Transm Dis , vol.32 , pp. 1-6
    • Kiddugavu, M.G.1    Kiwanuka, N.2    Wawer, M.J.3
  • 26
    • 13244273800 scopus 로고    scopus 로고
    • Evaluation of syphilis in patients with HIV infection in Nigeria
    • Nnoruka EN, Ezeoke AC. Evaluation of syphilis in patients with HIV infection in Nigeria. Trop Med Int Health 2005;10:58-64.
    • (2005) Trop Med Int Health , vol.10 , pp. 58-64
    • Nnoruka, E.N.1    Ezeoke, A.C.2
  • 28
    • 33644547620 scopus 로고    scopus 로고
    • Audit of the use of benzathine penicillin, post-treatment syphilis serology and partner notification of patients with early infectious syphilis
    • DOI 10.1258/095646206775809231
    • Chauhan M, Serisha B, Sankar KN, et al. Audit of the use of benzathine penicillin, post-treatment syphilis serology and partner notification of patients with early infectious syphilis. Int J STD AIDS 2006;17:200-2. (Pubitemid 43295056)
    • (2006) International Journal of STD and AIDS , vol.17 , Issue.3 , pp. 200-202
    • Chauhan, M.1    Serisha, B.2    Sankar, K.N.3    Pattman, R.S.4    Schmid, M.L.5
  • 29
    • 33646015696 scopus 로고    scopus 로고
    • Syphilis and human immunodeficiency virus (HIV)-1 coinfection: Influence on CD4 T-cell count, HIV-1 viral load and treatment response
    • Kofoed K, Gerstoft J, Mathiesen LR, et al. Syphilis and human immunodeficiency virus (HIV)-1 coinfection: influence on CD4 T-cell count, HIV-1 viral load and treatment response. Sex Transm Dis 2006;33:143-8.
    • (2006) Sex Transm Dis , vol.33 , pp. 143-148
    • Kofoed, K.1    Gerstoft, J.2    Mathiesen, L.R.3
  • 30
    • 34248171226 scopus 로고    scopus 로고
    • Serological response to syphilis treatment in HIV-positive and HIV-negative patients attending sexually transmitted diseases clinics
    • Ghanem KG, Erbelding EJ, Wiener ZS, et al. Serological response to syphilis treatment in HIV-positive and HIV-negative patients attending sexually transmitted diseases clinics. Sex Transm Infect 2007;83:97-101.
    • (2007) Sex Transm Infect , vol.83 , pp. 97-101
    • Ghanem, K.G.1    Erbelding, E.J.2    Wiener, Z.S.3
  • 31
    • 39549122301 scopus 로고    scopus 로고
    • The outcome of treatment of early latent syphilis and syphilis with undetermined duration in HIV-infected and HIV-uninfected patients
    • Manavi K, McMillan A. The outcome of treatment of early latent syphilis and syphilis with undetermined duration in HIV-infected and HIV-uninfected patients. Int J STD AIDS 2007;18:814-18.
    • (2007) Int J STD AIDS , vol.18 , pp. 814-818
    • Manavi, K.1    McMillan, A.2
  • 32
    • 46349088214 scopus 로고    scopus 로고
    • Antiretroviral therapy is associated with reduced serologic failure rates for syphilis among HIV-infected patients
    • Ghanem KG, Moore RD, Rompalo AM, et al. Antiretroviral therapy is associated with reduced serologic failure rates for syphilis among HIV-infected patients. Clin Infect Dis 2008;47:258-65.
    • (2008) Clin Infect Dis , vol.47 , pp. 258-265
    • Ghanem, K.G.1    Moore, R.D.2    Rompalo, A.M.3
  • 33
    • 78751643765 scopus 로고    scopus 로고
    • Should early syphilis be treated differently in HIV positive and HIV negative individuals?
    • Brooklyn, NY. Abstract E-08
    • Should early syphilis be treated differently in HIV positive and HIV negative individuals? Brooklyn, NY. BASHH ASTDA 3rd Joint Conference, Brooklyn, NY, 2008, Abstract E-08.
    • BASHH ASTDA 3rd Joint Conference, Brooklyn, NY, 2008
  • 34
    • 66349104656 scopus 로고    scopus 로고
    • Should syphilis be treated differently in HIV-positive and HIV-negative individuals? Treatment outcomes at a university hospital, Brighton, UK
    • Warwick Z, Dean G, Fisher M. Should syphilis be treated differently in HIV-positive and HIV-negative individuals? Treatment outcomes at a university hospital, Brighton, UK. Int J STD AIDS 2009;20:229-30.
    • (2009) Int J STD AIDS , vol.20 , pp. 229-230
    • Warwick, Z.1    Dean, G.2    Fisher, M.3
  • 35
    • 55849087245 scopus 로고    scopus 로고
    • UK National guidelines on the management of syphilis 2008
    • Kingston M, French P, Goh B, et al. UK National guidelines on the management of syphilis 2008. Int J STD AIDS 2008;19:729-40.
    • (2008) Int J STD AIDS , vol.19 , pp. 729-740
    • Kingston, M.1    French, P.2    Goh, B.3
  • 36
    • 0034004074 scopus 로고    scopus 로고
    • A point mutation associated with bacterial macrolide resistance is present in both 23S rRNA genes of an erythromycin-resistant Treponema pallidum clinical isolate
    • Stamm LV, Bergen HL. A point mutation associated with bacterial macrolide resistance is present in both 23S rRNA genes of an erythromycin-resistant Treponema pallidum clinical isolate. Antimicrob Agents Chemother 2000;44:806-7.
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 806-807
    • Stamm, L.V.1    Bergen, H.L.2
  • 37
    • 3042727194 scopus 로고    scopus 로고
    • Macrolide resistance in Treponema pallidum in the United States and Ireland
    • Lukehart SA, Godornes C, Molini BJ, et al. Macrolide resistance in Treponema pallidum in the United States and Ireland. N Engl J Med 2004;351:154-8.
    • (2004) N Engl J Med , vol.351 , pp. 154-158
    • Lukehart, S.A.1    Godornes, C.2    Molini, B.J.3
  • 38
    • 66449134237 scopus 로고    scopus 로고
    • Macrolide treatment failure in a case of secondary syphilis: A novel A2059G mutation in the 23S rRNA gene of Treponema pallidum subsp. pallidum
    • Matejkova P, Flasarova M, Zakoucka H, et al. Macrolide treatment failure in a case of secondary syphilis: a novel A2059G mutation in the 23S rRNA gene of Treponema pallidum subsp. pallidum. J Med Microbiol 2009;58:832-6.
    • (2009) J Med Microbiol , vol.58 , pp. 832-836
    • Matejkova, P.1    Flasarova, M.2    Zakoucka, H.3
  • 39
    • 0026425147 scopus 로고
    • Serologic response to treatment of infectious syphilis
    • Romanowski B, Sutherland R, Fick GH, et al. Serologic response to treatment of infectious syphilis. Ann Intern Med 1991;114:1005-9.
    • (1991) Ann Intern Med , vol.114 , pp. 1005-1009
    • Romanowski, B.1    Sutherland, R.2    Fick, G.H.3
  • 40
    • 34249331317 scopus 로고    scopus 로고
    • Interpreting cerebrospinal fluid pleocytosis in HIV in the era of potent antiretroviral therapy
    • Marra CM, Maxwell CL, Collier AC, et al. Interpreting cerebrospinal fluid pleocytosis in HIV in the era of potent antiretroviral therapy. BMC Infect Dis 2007;7:37.
    • (2007) BMC Infect Dis , vol.7 , pp. 37
    • Marra, C.M.1    Maxwell, C.L.2    Collier, A.C.3
  • 41
    • 1542368033 scopus 로고    scopus 로고
    • B lymphocyte dysfunctions in HIV infection
    • De Milito A. B lymphocyte dysfunctions in HIV infection. Curr HIV Res 2004;2:11-21.
    • (2004) Curr HIV Res , vol.2 , pp. 11-21
    • De Milito, A.1
  • 42
    • 33947724865 scopus 로고    scopus 로고
    • Déjà Vu all over again: When to perform a lumbar puncture in HIVinfected patients with syphilis
    • Marra CM. Déjà Vu all over again: When to perform a lumbar puncture in HIVinfected patients with syphilis. Sex Transm Dis 2007;34:145-6.
    • (2007) Sex Transm Dis , vol.34 , pp. 145-146
    • Marra, C.M.1
  • 43
    • 62449209211 scopus 로고    scopus 로고
    • Lumbar puncture in HIV-infected patients with syphilis and no neurologic symptoms
    • Ghanem KG, Moore RD, Rompalo AM, et al. Lumbar puncture in HIV-infected patients with syphilis and no neurologic symptoms. Clin Infect Dis 2009;48:816-21.
    • (2009) Clin Infect Dis , vol.48 , pp. 816-821
    • Ghanem, K.G.1    Moore, R.D.2    Rompalo, A.M.3
  • 44
    • 33947401424 scopus 로고    scopus 로고
    • Current controversies in the management of adult syphilis
    • Stoner BP. Current controversies in the management of adult syphilis. Clin Infect Dis 2007;44(Suppl 3):S130-46.
    • (2007) Clin Infect Dis , vol.44 , Issue.SUPPL. 3
    • Stoner, B.P.1
  • 45
    • 72849114396 scopus 로고    scopus 로고
    • Dilemmas in the management of syphilis: A survey of infectious diseases experts
    • Dowell D, Polgreen PM, Beekmann SE, et al. Dilemmas in the management of syphilis: a survey of infectious diseases experts. Clin Infect Dis 2009;49:1526-9.
    • (2009) Clin Infect Dis , vol.49 , pp. 1526-1529
    • Dowell, D.1    Polgreen, P.M.2    Beekmann, S.E.3
  • 46
    • 72849141007 scopus 로고    scopus 로고
    • When guidelines don't guide the physician
    • Gross PA. When guidelines don't guide the physician. Clin Infect Dis 2009;49:1530-1.
    • (2009) Clin Infect Dis , vol.49 , pp. 1530-1531
    • Gross, P.A.1
  • 47
    • 77949898564 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention. Atlanta, GA: Department of Health and Human Services
    • Centers for Disease Control and Prevention. Sexually transmitted disease surveillance, 2008. Atlanta, GA: Department of Health and Human Services, 2009.
    • (2009) Sexually Transmitted Disease Surveillance, 2008


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.