Influence of needle-shaped drug particles on the solid lipid extrusion process

Powder Technology

Volumn 207, Issue 1-3, 2011, Pages 407-413

  Witzleb, Rieke ^a   Kanikanti, Venkata Rangarao ^b   Hamann, Hans Jürgen ^b   Kleinebudde, Peter ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b BAYER AG   (Germany)

Author keywords

Die diameter; Milling; Needle; Particle shape; Screw setup; Solid lipid extrusion

Indexed keywords

BEFORE AND AFTER; BROKEN DOWN; DIE DIAMETER; DIE GEOMETRY; DRUG CRYSTALS; DRUG LOAD; EXTRUDATES; ISOMETRIC PARTICLES; MESALAZINE; MILLING; PARTICLE SHAPE; PARTICLE SIZE AND SHAPE; PROCESS PARAMETERS; PROCESSING PERFORMANCE; SOLID LIPID EXTRUSION; SURFACE TEXTURES;

CRYSTALS; DIES; MILLING (MACHINING); NEEDLES; SCREWS;

EXTRUSION;

CAFFEINE; MESALAZINE; PRAZIQUANTEL;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG DETERMINATION; DRUG FORMULATION; DRUG MIXTURE; DRUG STRUCTURE; PARTICLE SIZE; PELLET EXTRUSION; PHYSICAL PHASE; POWDER; SOLID LIPID EXTRUSION;

EID: 78751584882     PISSN: 00325910     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.powtec.2010.11.027     Document Type: Article

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