Altered ultrastructure of mitochondrial membranes is strongly associated with unexplained asthenozoospermia

Fertility and Sterility

Volumn 95, Issue 2, 2011, Pages 641-646

  Pelliccione, Fiore ^a   Micillo, Alessandro ^a   Cordeschi, Giuliana ^a   DAngeli, Anatolia ^a   Necozione, Stefano ^a   Gandini, Loredana ^b   Lenzi, Andrea ^b   Francavilla, Felice ^a   Francavilla, Sandro ^a  

^a UNIVERSITY OF L'AQUILA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Asthenozoospermia; mitochondria; sperm tail middle piece; sperm ultrastructure

Indexed keywords

ARTICLE; ASTHENOSPERMIA; CELL ULTRASTRUCTURE; CLINICAL ARTICLE; CONTROLLED STUDY; GENETIC DISORDER; HUMAN; MALE; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; SPERM; SPERMATOZOON MOTILITY; SPERMATOZOON TAIL;

ASTHENOZOOSPERMIA; EJACULATION; HUMANS; MALE; MITOCHONDRIAL DISEASES; MITOCHONDRIAL MEMBRANES; RETROSPECTIVE STUDIES; SEMEN ANALYSIS; SPERM RETRIEVAL; SPERM TAIL; SPERMATOZOA;

EID: 78751581757     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2010.07.1086     Document Type: Article

References (36)

1. L. Zamboni The ultrastructural pathology of the spermatozoon as a cause of infertility: the role of electron microscopy in the evaluation of semen quality Fertil Steril 48 1987 711 734
2. H.E. Chemes, and V.Y. Rawe Sperm pathology: a step beyond descriptive morphology. Origin, characterization and fertility potential of abnormal sperm phenotypes in infertile men Hum Reprod Update 9 2003 405 428
3. S. Francavilla, G. Cordeschi, F. Pelliccione, M. Bocchio, and F. Francavilla Isolate teratozoospermia. A cause of male sterility in the era of ICSI? Front Biosci 12 2007 69 88
4. S. Francavilla, F. Pelliccione, G. Cordeschi, S. Necozione, R. Santucci, and M. Bocchio Utrastructural analysis of asthenozoospermic ejaculates in the era of assisted procreation Fertil Steril 85 2006 940 946
5. Y.H. Kim, G. Haidl, M. Schaefer, U. Egner, and J.C. Herr Compartmentalization of a unique ADP/ATP carrier protein SFEC (Sperm Flagellar Energy Carrier, AAC4) with glycolytic enzymes in the fibrous sheath of the human sperm flagellar principal piece Dev Biol 302 2007 463 476
6. E. Ruiz-Pesini, C. Diez-Sanchez, M.J. Lopez-Perez, and J.A. Enriquez The role of the mitochondrion in sperm function: Is there a place for oxidative phosphorylation or is this a purely glycolytic process? Curr Topics Dev Biol 77 2007 3 19
7. P.H. Hung, M.G. Miller, S.A. Meyers, and A. Vande Voort Sperm mitochondrial integrity is not required for hyperactivated motility, zona binding or acrosome reaction in the rhesus macaque Biol Reprod 79 2008 367 375
8. J.M. Nascimento, L.Z. Shi, J. Tam, C. Chandsawangbhuwana, B. Durrant, and E.L. Botvinick Comparison of glycolysis and oxidative phosphorylation as energy sources for mammalian sperm motility, using the combination of fluorescence imaging, laser tweezers, and real-time automated tracking and trapping J Cell Physiol 217 2008 745 751
9. M. Piasecka, and J. Kawiak Sperm mitochondria of patients with normal sperm motility and with asthenozoospermia: morphological and functional study Folia Histochem Cytobiol 41 2003 125 138
10. C. Marchetti, N. Jouy, B. Leroy-Martin, A. Defossez, P. Formstecher, and P. Marchetti Comparison of four fluorochromes for the detection of the inner mitochondrial membrane potential in human spermatozoa and their correlation with sperm motility Hum Reprod 19 2004 2267 2276
11. G. Barroso, S. Taylor, M. Morshedi, F. Manzur, F. Gavino, and S. Oehninger Mitochondrial membrane potential integrity and plasma membrane translocation of phosphatidylserine as early apoptotic markers: a comparison of two different subpopulations Fertil Steril 85 2006 149 154
12. F. Gallon, C. Marchetti, N. Jouy, and P. Marchetti The functionality of mitochondria differentiates human spermatozoa with high and low fertilizing capability Fertil Steril 85 2006 1526 1530
13. V.Y. Rawe, G.D. Galaverna, A.A. Acosta, S.B. Olmedo, and H.E. Chemes Incidence of tail structure distortions associated with dysplasia of the fibrous sheath in human spermatozoa Hum Reprod 16 2001 879 886
14. A.J. Mundy, T.A. Ryder, and D.K. Edmonds Asthenozoospermia and the human sperm mid-piece Hum Reprod 10 1995 116 119
15. M. Courtade, C. Lagorce, L. Bujan, C. Caratero, and R. Mieusset Clinical characteristics and light and transmission electron microscopic sperm defects of infertile men with persistent unexplained asthenozoospermia Fertil Steril 70 1998 297 304
16. K. Gopalkrishnan, V. Padwal, S. D'Souza, and R. Shah Severe asthenozoospermia: a structural and functional study Int J Androl 18 Suppl 1 1995 67 74
17. C. De Martino, A. Floridi, M.L. Marcante, W. Malorni, P. Scorza Barcellona, and M. Bellocci Morphological, histochemical and biochemical studies on germ cell mitochondria of normal rats Cell Tisse Res 196 1979 1 22
18. K. Nakada, A. Sato, K. Yoshida, T. Morita, H. Tanaka, and S.-I. Inoue Mitochondria-related male infertility Proc Natl Acad Sci U S A 103 2006 15148 15153
19. World Health Organization WHO laboratory manual for the examination of human semen and sperm-cervical mucus interaction 1999 Cambridge University Press Cambridge
20. F. Francavilla, R. Romano, R. Santucci, G. La Verghetta, P. D'Abrizio, and S. Francavilla Naturally-occurring antisperm antibodies in men: interference with fertility and implications for treatment Front Biosci 4 1999 9 25
21. C.R. Nahoum, and D. Cardozo Staining for volumetric count of leukocytes in semen and prostrate-vesicular fluid Fertil Steril 34 1980 68 69
22. R. Eliasson, and L. Treichl Supravital staining of human spermatozoa Fertil Steril 22 1971 134 137
23. K. Hirai Specific affinity of oxidized amine dye (radical intermediate) for heme enzymes: study in light and electron microscopy and spectrophotometry Acta Histochem Cytochem 1 1968 43 54
24. W. Anderson The localization of cytochrome oxidase activity during mitochondrial specialization in spermatogenesis of prosobranch snails J Histochem Cytochem 18 1970 201 210
25. A. Perl, Y. Qian, K.R. Chohan, C.R. Shirley, W. Amidon, and S. Banerjee Transaldolare is essential for maintenance of the mitochondrial transmembrane potential and fertility of spermatozoa Proc Natl Acad Sci U S A 103 2006 14813 14818
26. P.T. Saunders, M.R. Millar, A.P. West, and R.M. Sharpe Mitochondrial cytochrome C oxidase II messanger ribonucleic acid is expressed in pachytene spermatocytes at high levels and in a stage-dependent manner during spermatogenesis in the rat Biol Reprod 48 1993 57 67
27. J.M. Petit, M.H. Ratinaud, E. Cordelli, M. Spano, and R. Julien Mouse testis cell sorting according to DNA and mitochondrial changes during spermatogenesis Cytometry 19 1995 304 312
28. M. Treinin, and G. Simchen Mitochondrial activity is required for the expression of IME1, a regulator of meiosis in yeast Curr Genet 23 1993 223 227
29. R.J. Aitken, D. Buckingham, K. West, F.C. Wu, K. Zikopoulos, and D.W. Richardson Differential contribution of leucocytes and spermatozoa to the generation of reactive oxygen species in the ejaculates of oligozoospermic patients and fertile donors J Reprod Fertil 94 1992 451 462
30. G.N. De Iuliis, J.K. Wingate, A.J. Koppers, E.A. McLaughlin, and R.J. Aitken Definitive evidence for the nonmitochondrial production of superoxide anion by human spermatozoa J Clin Endocrinol Metab 91 2006 1968 1975
31. E. de Lamirande, and C. Gagnon Reactive oxygen species and human spermatozoa. II. Depletion of adenosine triphosphate plays an important role in the inhibition of sperm motility J Androl 13 1992 379 386
32. W.C. Ford Glycolysis and sperm motility: does a spoonful of sugar help the flagellum go round? Hum Reprod Update 12 2006 269 274
33. A.J. Koppers, M.L. Garg, and R.J. Aitken Stimulation of mitochondrial reactive oxygen species production by unesterified, unsaturated fatty acids in defective human spermatozoa Free Radic Biol Med 48 2010 112 119
34. S.H. Pilder, P. Olds-Clarke, D.M. Phillips, and L.M. Silver Hybrid sterility-6: a mouse t complex locus controlling sperm flagella assembly and movement Dev. Biol 159 1993 631 642
35. S.H. Pilder, P. Olds-Clarke, J.M. Orth, W.F. Jester, and L. Dugan Hst7: a male sterility mutation perturbing sperm motility, flagellar assembly, and mitochondrial sheath differentiation J Androl 18 1997 663 671
36. M.G. Hull, C.M. Glazener, N.J. Kelly, D.I. Conway, P.A. Foster, and R.A. Hunton Population study of causes, treatment, and outcome of infertility Br Med J (Clin Res Ed) 291 1985 1693 1697