Expression of the chemokine receptor CCR6 correlates with a favorable prognosis in patients with adenocarcinoma of the lung

Tumor Biology

Volumn 32, Issue 1, 2011, Pages 197-202

  Minamiya, Yoshihiro ^a   Saito, Hajime ^a   Takahashi, Naoko ^a   Ito, Manabu ^a   Toda, Hiroshi ^a   Ono, Takashi ^a   Konno, Hayato ^a   Motoyama, Satoru ^a   Ogawa, Jun Ichi ^a  

^a AKITA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Adenocarcinoma; Chemokine receptor; Lung cancer; Prognosis

Indexed keywords

CHEMOKINE RECEPTOR CCR6; MESSENGER RNA;

ADULT; ARTICLE; CANCER SURVIVAL; CONTROLLED STUDY; DISEASE FREE SURVIVAL; FEMALE; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC CORRELATION; HUMAN; HUMAN TISSUE; LUNG ADENOCARCINOMA; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROGNOSIS; QUANTITATIVE STUDY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEX DIFFERENCE; SURVIVAL TIME; TUMOR VOLUME;

EID: 78751579002     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-010-0113-x     Document Type: Article

References (18)

1. M Mareel A Leroy 2003 Clinical, cellular, and molecular aspects of cancer invasion Physiol Rev 83 337 76 1:CAS:528:DC%2BD3sXjtVagtr8%3D 12663862
2. JM Wang X Deng W Gong S Su 1998 Chemokines and their role in tumor growth and metastasis J Immunol Methods 220 1 17 1:CAS:528:DyaK1cXntVygsL0%3D 10.1016/S0022-1759(98)00128-8 9839921 (Pubitemid 28527062)
3. E Schutyser S Struyf J Van Damme 2003 The CC chemokine CCL20 and its receptor CCR6 Cytokine Growth Factor Rev 14 409 26 1:CAS:528: DC%2BD3sXms1Oqsbc%3D 10.1016/S1359-6101(03)00049-2 12948524 (Pubitemid 37099454)
4. P Ghadjar C Rubie DM Aebersold U Keilholz 2009 The chemokine CCL20 and its receptor CCR6 in human malignancy with focus on colorectal cancer Int J Cancer 125 741 5 1:CAS:528:DC%2BD1MXnsFeltLY%3D 10.1002/ijc.24468 19480006
5. J Dellacasagrande OJ Schreurs PO Hofgaard H Omholt S Steinsvoll K Schenck B Bogen Z Dembic 2003 Liver metastasis of cancer facilitated by chemokine receptor CCR6 Scand J Immunol 57 534 44 1:CAS:528:DC%2BD3sXlsVKku7s%3D 10.1046/j.1365-3083.2003.01263.x 12791091 (Pubitemid 36734993)
6. P Ghadjar C Loddenkemper SE Coupland A Stroux M Noutsias E Thiel F Christoph K Miller C Scheibenbogen U Keilholz 2008 Chemokine receptor CCR6 expression level and aggressiveness of prostate cancer J Cancer Res Clin Oncol 134 1181 9 1:CAS:528:DC%2BD1cXht1anu7%2FI 10.1007/s00432-008-0403-5 18465142
7. S Brand T Olszak F Beigel J Diebold JM Otte ST Eichhorst B Göke J Dambacher 2006 Cell differentiation dependent expressed CCR6 mediates ERK-1/2, SAPK/JNK, and Akt signaling resulting in proliferation and migration of colorectal cancer cells J Cell Biochem 97 709 23 1:CAS:528:DC%2BD28Xis1Crs7c%3D 10.1002/jcb.20672 16215992
8. C Rubie VO Frick M Wagner C Weber B Kruse K Kempf J König B Rau M Schilling 2006 Chemokine expression in hepatocellular carcinoma versus colorectal liver metastases World J Gastroenterol 12 6627 33 1:CAS:528:DC%2BD2sXntVahtro%3D 17075975
9. C Rubie V Oliveira K Kempf M Wagner B Tilton B Rau B Kruse J Konig M Schilling 2006 Involvement of chemokine receptor CCR6 in colorectal cancer metastasis Tumour Biol 27 166 74 1:CAS:528:DC%2BD28Xkt12qt7s%3D 10.1159/000092777 16641550
10. H Uchida Y Iwashita A Sasaki K Shibata T Matsumoto M Ohta S Kitano 2006 Chemokine receptor CCR6 as a prognostic factor after hepatic resection for hepatocellular carcinoma J Gastroenterol Hepatol 21 161 8 1:CAS:528: DC%2BD28XhtlajsLjL 10.1111/j.1440-1746.2005.04157.x 16706828
11. J Wang L Xi W Gooding TE Godfrey RL Ferris 2005 Chemokine receptors 6 and 7 identify a metastatic expression pattern in squamous cell carcinoma of the head and neck Adv Otorhinolaryngol 62 121 33 1:CAS:528:DC%2BD2MXksF2jsA%3D%3D 15608423
12. J Wang L Xi JL Hunt W Gooding TL Whiteside Z Chen TE Godfrey RL Ferris 2004 Expression pattern of chemokine receptor 6 (CCR6) and CCR7 in squamous cell carcinoma of the head and neck identifies a novel metastatic phenotype Cancer Res 64 1861 6 1:CAS:528:DC%2BD2cXhslersrg%3D 10.1158/0008-5472.CAN-03-2968 14996750 (Pubitemid 38428712)
13. A Sutherland JF Mirjolet A Maho M Parmentier 2007 Expression of the chemokine receptor CCR6 in the Lewis lung carcinoma (LLC) cell line reduces its metastatic potential in vivo Cancer Gene Ther 14 847 57 1:CAS:528: DC%2BD2sXhtVagtbnL 10.1038/sj.cgt.7701074 17599091 (Pubitemid 47402379)
14. T Naruke K Suemasu S Ishikawa 1978 Lymph node mapping and curability at various levels of metastasis in resected lung cancer J Thorac Cardiovasc Surg 76 832 839 1:STN:280:DyaE1M%2FltFOnsg%3D%3D 713589
15. TF Kimsey AS Campbell D Albo M Wilson TN Wang 2004 Co-localization of macrophage inflammatory protein-3alpha (Mip-3alpha) and its receptor, CCR6, promotes pancreatic cancer cell invasion Cancer J 10 374 80 1:CAS:528: DC%2BD2MXhtVCms70%3D 10.1097/00130404-200411000-00007 15701269
16. J Reibman Y Hsu LC Chen B Bleck 2003 Gordon T. Airway epithelial cells release MIP-3alpha/CCL20 in response to cytokines and ambient particulate matter. Am J Respir Cell Mol Biol 28 648 54 1:CAS:528:DC%2BD3sXks1KitrY%3D 10.1165/rcmb.2002-0095OC 12760962 (Pubitemid 36681535)
17. DJ Fitzhugh S Naik SW Caughman ST Hwang 2000 C-C chemokine receptor 6 is essential for arrest of a subset of memory T cells on activated dermal microvascular endothelial cells under physiologic flow conditions in vitro J Immunol 165 6677 81 1:CAS:528:DC%2BD3cXovFyht7c%3D 11120783
18. C Ho N Murray J Laskin B Melosky H Anderson G Bebb 2005 Asian ethnicity and adenocarcinoma histology continues to predict response to gefitinib in patients treated for advanced non-small cell carcinoma of the lung in North America Lung Cancer 49 225 31 10.1016/j.lungcan.2005.02.011 15925429 (Pubitemid 40966751)