Effect and mechanism of senkyunolide i as an anti-migraine compound from Ligusticum chuanxiong

Journal of Pharmacy and Pharmacology

Volumn 63, Issue 2, 2011, Pages 261-266

  Wang, Yi Han ^a   Liang, Shuang ^a   Xu, De Sheng ^b   Lin, Xiao ^a   He, Chun Yong ^a   Feng, Yi ^a   Hong, Yan Long ^a  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b SHUGUANG HOSPITAL AFFILIATED TO SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

acetic acid induced writhing test; hot plate test; migraine; monoamine neurotransmitters; nitric oxide; senkyunolide I

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; 5 HYDROXYTRYPTOPHAN; ACETIC ACID; ANTIMIGRAINE AGENT; BUCINNAZINE; CAFFEINE PLUS ERGOTAMINE TARTRATE; DOPAMINE; NORADRENALIN; SENKYUNOLIDE I; SEROTONIN; UNCLASSIFIED DRUG;

5 HYDROXYINDOLEACETIC ACID BRAIN LEVEL; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOPAMINE BLOOD LEVEL; DOPAMINE BRAIN LEVEL; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG MECHANISM; FEMALE; HOT PLATE TEST; LIGUSTICUM CHUANXIONG; MOUSE; NONHUMAN; NORADRENALIN BLOOD LEVEL; NORADRENALIN BRAIN LEVEL; PAIN THRESHOLD; RAT; SEROTONIN BLOOD LEVEL; SEROTONIN BRAIN LEVEL; WRITHING TEST;

5-HYDROXYTRYPTOPHAN; ACETIC ACIDS; ANALGESICS; ANIMALS; BENZOFURANS; BRAIN; DOPAMINE; DRUGS, CHINESE HERBAL; HYDROXYINDOLEACETIC ACID; MICE; MIGRAINE DISORDERS; NEUROTRANSMITTER AGENTS; NITRIC OXIDE; NITROGLYCERIN; NOREPINEPHRINE; PAIN THRESHOLD; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN;

EID: 78751522088     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-7158.2010.01191.x     Document Type: Article

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