Effects of cadmium on proliferation, apoptosis, differentiation and mineralization in osteoblast in vitro

Fudan University Journal of Medical Sciences

Volumn 34, Issue 4, 2007, Pages 513-517

  Chen, Xiao ^a   Zhu, Guo Ying ^a   Wang, Li Hua ^a   Jin, Tai Yi ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Alkaline phosphatase; AO EB; Cadmium chloride; Cell apoptosis; Mineralization; Osteoblast

Indexed keywords

EID: 78751488520     PISSN: 16728467     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. WHQ, 1992. Environment Health criteria 134, cadmium. IPCS, Geneva.
2. Uriu K, Morimoto I, Kai K, et at. Uncoupling between bone formation and resorption inovariectomized rats with chronic cadmium exposure[J]. Toxicol Appl Pharmacol, 2000, 164 (3), 264 (Pubitemid 30314245)
3. Kosmider B, Zyner E, Osiecka R, et al. Induction of apoptosis and necrosis in A549 cells by the cis-Pt (II) complex of 3-aminoflavone in comparison with cis-DDP[J], Mutat Res, 2004, 563(1):61 (Pubitemid 39504759)
4. Aitio A, Tritscher A. Effects on health of cadmium- WHO approaches and conclusions[J]. Bio Metals ,2004, 17(5): 491 (Pubitemid 41214254)
5. Järup L, Alfvén T. Low level cadmium exposure, renal and bone effects - the OSCAR study[J]. Bio Metals, 2004, 17(5) : 505 (Pubitemid 41214257)
6. Zhu GY, Wang HF, Shi YX, et al. Environmental cadmium exposure and forearm bone density[J]. Bio Metals, 2004, 17 (5):499
7. Bertin G, Averbeck D. Cadmium, cellular effects, modifications of biomolecules, modulation of DNA repair and genotoxic consequences (a review) [J]. Biochimie, 2006, 88 (11) : 1549 (Pubitemid 44751344)
8. Stec B, Holtz KM, Kantrowitz R. A revised mechanism for the alkaline phosphatase reaction involving three metal ions[J]. J Mol Bio, 2000, 299 (5) : 1303
9. Hoshi K, Ejiri S, Ozawa H. Localizational alterations of calcium , phosphorus, and calcification-related organics such as proteoglycans and alkaline phosphatase during bone calcification [J]. J Bone Miner Res ,2001,16(2):289 (Pubitemid 32105410)
10. Conconi MT, Tommasini M. Muratori E, et al. Essential amino acids increase the growth and alkaline phosphatase activity in osteoblasts cultured in vitro[J]. Il, 2001, 56(11): 755 (Pubitemid 32913097)
11. Mazorra MT, Rubio JA, Blasco J. Acid and alkaline phosphatase activities in the clam Scrobicularia plana: characteristics and effects of heavy metals[J]. Comp Biochem Physiol B, 2002, 131(2), 241 (Pubitemid 34127794)
12. Carllson L, Lundholm CE. Characterisation of the effects of cadmium on the release of calcium and the activity of some enzymes from neonatal mouse calvaria in culture[J]. Comp Biochem Physiol, 1996, 115(3): 251
13. Iwami K, Moriyama T. Comparative effect of cadmium on osteoblastic cells and osteoclastic cells[J]. Arch Toxicol, 1993, 67(5):352. (Pubitemid 23180982)
14. Gur E, Waner T, Barushka-Eizik O, et al. Effect of cadmium on bone repair in young rats[J]. Toxicol Enviro Health, 1995, 45(3):249
15. Miyahara T. Yamada H. Takeuchi M, et al. Inhibitory effects of cadmium on in vitro calcification of a clonal osteogenic cell, MC3T3-E1[J]. Toxicol Appl Pharmacol, 1988, 96(1):52
16. Horiguchi H. Oguma E, Sasaki S, et al. Environmental exposure to cadmium at a level insufficient to induce renal tubular dysfunction does not affect bone density among female Japanese farmers[J]. Environ Res, 2005, 97(1): 83 (Pubitemid 39336394)
17. Jin TY, Nordberg GF, Ye TT, et al. Osteoporosis and renal dysfunction in a general population exposed to cadmium in China[J]. Environ Res, 2004, 96(3): 353
18. 45 Ca in mouse dams on a calcium-deficient diet: Evidence of Itai-Itai-like syndrome[J]. Toxicol Appl Pharmacol, 1994, 127(2):320