Sharing unexpected biomarker results with study participants

Environmental Health Perspectives

Volumn 119, Issue 1, 2011, Pages 1-5

  Hernick, Ann D ^a   Kathryn Brown, M ^b   Pinney, Susan M ^b   Biro, Frank M ^c   Ball, Kathleen M ^a   Bornschein, Robert L ^b  

^a Breast Cancer Alliance of Greater Cincinnati   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; PERFLUOROOCTANE;

ARTICLE; BIOETHICS; BLOOD LEVEL; CHILD; ENVIRONMENTAL EXPOSURE; FEASIBILITY STUDY; FEMALE; HUMAN; INFORMATION DISSEMINATION; INTERDISCIPLINARY RESEARCH; INTERPERSONAL COMMUNICATION; PILOT STUDY; PRESCHOOL CHILD; PRIORITY JOURNAL; PUBLIC HEALTH; SCHOOL CHILD; UNITED STATES; URINE LEVEL;

BIOLOGICAL MARKERS; CHILD; DISCLOSURE; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL MONITORING; ENVIRONMENTAL POLLUTANTS; FEMALE; FLAME RETARDANTS; FLUOROCARBONS; HUMANS; OCTANOIC ACIDS; RESEARCH SUBJECTS;

EID: 78751472771     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1001988     Document Type: Article

References (18)

1. Brody JG, Morello-Frosch R, Brown P, Rudel RA, Altman RG, Frye M, et al. 2007. Improving disclosure and consent: "is it safe?" New ethics for reporting personal exposures to environmental chemicals. Am J Public Health 97:1547-1554.
2. Calafat A, Kuklenyik Z, Reidey J, Caudill S, Tully JS, Needham LL. 2007. Serum concentrations of 11 poly-fluoroalkyl compounds in the US population: data from the National Health and Nutrition Examination Survey (NHANES) 1999-2000. Environ Sci Technol 41:2237-2242.
3. Clavel-Chapelon F. 2002. Differential effects of reproductive factors on the risk of pre- and post-menopausal breast cancer. Results from a large cohort of French women. Br J Cancer 86:723-727.
4. Deck W, Kosatsky T. 1999. Communicating their individual results to participants in an environmental exposure study: insights from clinical ethics. Environ Res 80:S223-S229.
5. Emmett EA, Zhang H, Shofer FS, Freeman D, Rodway NV, Desai C, et al. 2006. Community exposure to perfuorooc-tanoate: relationships between serum levels and certain health parameters. J Occup Environ Med 48:771-779.
6. Fernandez CV, Kodish E, Weijer C. 2003. Informing study participants of research results: an ethical imperative. IRB 25:12-19.
7. Galvez MP, Peters R, Graber N, Forman J. 2007. Effective risk communication in children's environmental health: lessons learned from 9/11. Pediatr Clin N Am 54:33-46.
8. Hiatt RA, Haslam SZ, Osuch J. 2009. The Breast Cancer and the Environment Research Centers: transdisciplinary research on the role of the environment in breast cancer etiology. Environ Health Perspect 117:1814-1822.
9. Kriebel D, Tickner J, Epstein P, Lemons J, Levins R, Loechler EL, et al. 2001. The precautionary principle in environmental science. Environ Health Perspect 109:871-876.
10. Morello-Frosch R, Brody JG, Brown P, Altman RG, Rudel RA, Perez C. 2009. Toxic ignorance and right-to-know in biomonitoring results communication: a survey of scientists and study participants. Environ Health 8:6-28.
11. National Center for Environmental Health. 2005. Third National Report on Human Exposure to Environmental Chemicals. Atlanta, GA:Centers for Disease Control and Prevention.
12. The National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research. 1979. The Belmont Report: Ethical Principles and Guidelines for the Protection of Human Subjects of Research. Available: http://ohsr.od.nih.gov/guidelines/belmont.html [accessed 22 July 2010].
13. Resnik DB. 2009. Environmental health research and the observer's dilemma. Environ Health Perspect 117:1191-1194.
14. Rosenfeld PL. 1992. The potential of transdisciplinary research for sustaining and extending linkages between the health and social sciences. Soc Sci Med 35:1343-1357.
15. Sly PD, Eskenazi B, Pronczuk J, Šrám R, Diaz-Barriga F, Machin DG, et al. 2009. Ethical issues in measuring bio-markers in childrenís environmental health. Environ Health Perspect 117:1185-1190.
16. Tamburlini G, Ebi K, Menne B. 2002. Children's special vulnerability to environmental health hazards: an overview. In: Children's Health and Environment: A Review of Evidence (Tamburlini G, von Ehrenstein OS, Bertollini R, eds). Rome:WHO Regional Offce for Europe, 18-28.
17. Wolff MS, Teitelbaum SL, Windham G, Pinney SM, Britton JA, Chelimo C, et al. 2007. Pilot study of urinary biomarkers of phytoestrogens, phthalates and phenols in girls. Environ Health Perspect 115:116-121.
18. Wones R, Pinney SM, Buckholtz JM, Deck-Tebbe C, Freyberg R, Pesce A. 2009. Medical monitoring: a benefcial remedy for residents living near an environmental hazard site. J Occup Environ Med 51:1374-1383.