Hybrid approach of ventricular assist device and autologous bone marrow stem cells implantation in end-stage ischemic heart failure enhances myocardial reperfusion

Journal of Translational Medicine

Volumn 9, Issue , 2011, Pages

  Anastasiadis, Kyriakos ^a   Antonitsis, Polychronis ^a   Argiriadou, Helena ^a   Koliakos, Georgios ^b   Doumas, Argyrios ^b   Khayat, Andre ^c   Papakonstantinou, Christos ^a   Westaby, Stephen ^d  

^a AHEPA UNIVERSITY HOSPITAL   (Greece)

^b ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^c Caen Hospital   (France)

^d JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS; ARTIFICIAL HYBRIDIZATION; ASSISTED CIRCULATION; AUTOLOGOUS BONE MARROW TRANSPLANTATION; CELL VIABILITY; HEART FUNCTION; HEART HYPERTROPHY; HEART LEFT VENTRICLE CONTRACTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE REPERFUSION; HEART PERFORMANCE; HEART TRANSPLANTATION; HEMATOPOIETIC STEM CELL; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; ISCHEMIC HEART DISEASE; NOTE; PROGNOSIS; REGULATORY MECHANISM; STEM CELL TRANSPLANTATION; TISSUE REGENERATION; AUTOTRANSPLANTATION; BONE MARROW TRANSPLANTATION; EVALUATION; HEART ASSIST DEVICE; HEART FAILURE; HEART MUSCLE ISCHEMIA; HEMATOPOIETIC STEM CELL TRANSPLANTATION; INSTRUMENTATION; METHODOLOGY; MULTIMODALITY CANCER THERAPY; REVIEW; UPREGULATION;

BONE MARROW TRANSPLANTATION; COMBINED MODALITY THERAPY; HEART FAILURE; HEART-ASSIST DEVICES; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION; TRANSPLANTATION, AUTOLOGOUS; UP-REGULATION;

EID: 78651519204     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-9-12     Document Type: Note

References (26)

1. Hetzer R, Muller JH, Weng Y, Meyer R, Dandel M. Bridging-to-recovery. Ann Thorac Surg 2001, 71:S109-113. 10.1016/S0003-4975(00)02638-2, 11265844.
2. Simon MA, Kormos RL, Murali S, Nair P, Hefernan M, Gorcsan J, Winowich S, McNamara DM. Myocardial recovery using ventricular assist devices. Prevalence, clinical characteristics and outcomes. Circulation 2005, 112(Suppl):I32-36.
3. Birks EJ, Tansley PD, Hardy J, George RS, Bowles CT, Burke M, Banner NR, Khaghani A, Yacoub MH. Left ventricular assist device and drug therapy for the reversal of heart failure. N Engl J Med 2006, 355:1873-1884. 10.1056/NEJMoa053063, 17079761.
4. Klotz S, Jan Danser AH, Burkhoff D. Impact of left ventricular assist device (LVAD) support on the cardiac reverse remodeling process. Prog Biophys Mol Biol 2008, 97:479-496. 10.1016/j.pbiomolbio.2008.02.002, 18394685.
5. von Harsdorf R, Poole-Wilson PA, Dietz R. Regenative capacity of the myocardium: implications for treatment of heart failure. Lancet 2004, 363:1306-1313. 10.1016/S0140-6736(04)16006-6, 15094278.
6. Rahimtoola SH. The hibernating myocardium. Am Heart J 1989, 117:211-221. 10.1016/0002-8703(89)90685-6, 2783527.
7. Elsasser A, Muller KD, Skwara W, Bode C, Kubler W, Vogt AM. Severe energy deprivation of human hibernating myocardium as possible common pathomechanism of contractile dysfunction, structural degeneration and cell death. J Am Coll Cardiol 2002, 39:1189-1198. 10.1016/S0735-1097(02)01735-7, 11923045.
8. McMurray JV, Pfeffer MA. Heart failure. Lancet 2005, 365:1877-1889. 10.1016/S0140-6736(05)66621-4, 15924986.
9. Gheorghiade M, Bonow RO. Chronic heart failure in the United States: a manifestation of coronary artery disease. Circulation 1998, 97:282-289.
10. Westaby S. Advanced heart failure-an "off-the-shelf" solution?. Lancet 2008, 371:1898-1900. 10.1016/S0140-6736(08)60813-2, 18539210.
11. Westaby S, Siegenthaler M, Beyersdorf F, Massetti M, Pepper J, Khayat A, Hetzer R, Frazier OH. Destination therapy with a rotary blood pump and novel power delivery. Eur J Cardiothorac Surg 2010, 37:350-356.
12. Soppa GK, Barton PJ, Terraciano CM, Yacoub MH. Left ventricular assist device-induced molecular changes in the failing myocardium. Curr Opin Cardiol 2008, 23:206-218. 10.1097/HCO.0b013e3282fc7010, 18382208.
13. Jahanyar J, Youker KA, Torre-Amione G, Koerner MM, Bruckner B, Noon GP, Loebe M. Increased expression of stem cell factor and its receptor after left ventricular assist device support: A potential novel target for therapeutic interventions in heart failure. J Heart Lung Transplant 2008, 27:701-9. 10.1016/j.healun.2008.03.021, 18582797.
14. Letsou GV, Sdringola S, Gregoric ID, Patel V, Myers TV, Delgado RM, Frazier OH. Myocardial perfusion as assessed by positron emission tomography during long-term mechanical circulatory support. Congest Heart Fail 2006, 12:69-74. 10.1111/j.1527-5299.2006.04686.x, 16596039.
15. Orlic D, Kajstura J, Chimenti S, Jakoniuk I, Anderson SM, Li B, Pickel J, McKay R, Nadal-Ginard B, Bodine DM, Leri A, Anversa P. Bone marrow cells regenerate infarcted myocardium. Nature 2001, 410:701-705. 10.1038/35070587, 11287958.
16. Murry CE, Soonpaa MH, Reinecke H, Nakajima H, Nakajima HO, Rubart M, Pasumarthi KB, Virag JI, Bartelmez SH, Poppa V, Bradford G, Dowell JD, Williams DA, Field LJ. Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts. Nature 2004, 428:664-668. 10.1038/nature02446, 15034593.
17. Urbanek K, Torella D, Sheikh F, De Angelis A, Nurzynska D, Silvestri F, Beltrami CA, Bussani R, Beltrami AP, Quaini F, Bolli R, Leri A, Kajstura J, Anversa P. Myocardial regeneration by activation of multipotent cardiac stem cells in ischemic heart failure. Proc Natl Acad Sci USA 2005, 102:8692-8697. 10.1073/pnas.0500169102, 1150816, 15932947.
18. Fedak PW. Paracrine effects of cell transplantation: Modifying ventricular remodeling in the failing heart. Semin Thorac Cardiovasc Surg 2008, 20:87-93. 10.1053/j.semtcvs.2008.04.001, 18707639.
19. Mazhari R, Hare JM. Mechanisms of action of mesenchymal stem cells in cardiac repair: potential influences on the cardiac stem cell niche. Nat Clin Pract Cardiovasc Med 2007, 4(Suppl):S21-26. 10.1038/ncpcardio0770, 17230212.
20. Kinnaird T, Stabile E, Burnett MS, Shou M, Lee CW, Barr S, Fuchs S, Epstein SE. Local delivery of marrow-derived stromal cells augments collateral perfusion through paracrine mechanisms. Circulation 2004, 109:1543-1549. 10.1161/01.CIR.0000124062.31102.57, 15023891.
21. Ohnishi S, Sumiyoshi H, Kitamura S, Nagaya N. Mesenchymal stem cells attenuate cardiac fibroblast proliferation and collagen synthesis through paracrine actions. FEBS Lett 2007, 581:3961-3966. 10.1016/j.febslet.2007.07.028, 17662720.
22. Miyagawa S, Matsumiya G, Funatsu T, Yoshitatsu M, Sekiya N, Fukui S, Hoashi T, Hori M, Yoshikawa H, Kanakura Y, Ishikawa J, Aozasa K, Kawaguchi N, Matsuura N, Myoui A, Matsuyama A, Ezoe S, Iida H, Matsuda H, Sawa Y. Combined autologous cellular cardiomyoplasty using skeletal myoblasts and bone marrow cells for human ischemic cardiomyopathy with left ventricular assist system implantation: report of a case. Surg Today 2009, 39:133-136. 10.1007/s00595-008-3803-x, 19198991.
23. Gojo S, Kyo S, Nishimura S, Komiyama N, Kawai N, Bessho M, Sato H, Asakura T, Nishimura M, Ikebuchi K. Cardiac resurrection after bone-marrow-derived mononuclear cell transplantation during left ventricular assist device support. Ann Thorac Surg 2007, 83:661-662. 10.1016/j.athoracsur.2006.06.074, 17258005.
24. Nasseri BA, Kukucka M, Dandel M, Knosalla C, Potapov E, Lehmkuhl HB, Meyer R, Ebell W, Stamm C, Hetzer R. Intramyocardial delivery of bone marrow mononuclear cells and mechanical assist device implantation in patients with end-stage cardiomyopathy. Cell Transplant 2007, 16:941-949. 10.3727/096368907783338235, 18293893.
25. Maybaum S, Mancini D, Xydas S, Starling RC, Aaronson K, Pagani FD, Miller LW, Margulies K, McRee S, Frazier OH, Torre-Amione G, . LVAD Working Group Cardiac improvement during mechanical circulatory support: a prospective multicenter study of the LVAD Working Group. Circulation 2007, 115:2497-2505. 10.1161/CIRCULATIONAHA.106.633180, 17485581, LVAD Working Group.
26. Beeres SL, Bengel FM, Bartunek J, Atsma DE, Hill JM, Vanderheyden M, Penicka M, Schalij MJ, Wijns W, Bax JJ. Role of imaging in cardiac stem cell therapy. J Am Coll Cardiol 2007, 49:1137-1148. 10.1016/j.jacc.2006.10.072, 17367656.