Postejaculatory increase of prostatic triiodothyronine (T3) depends on sympathetic innervation in the rat

Biology of Reproduction

Volumn 84, Issue 1, 2011, Pages 118-123

  Delgado Gonzalez, Evangelina ^a   Aceves, Carmen ^a   Anguiano, Brenda ^a,b  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b INSTITUTO DE NEUROBIOLOGÍA   (Mexico)

Author keywords

Deiodinase; Ejaculation; Hypogastric nerve; Male reproductive tract; Male sexual function; Noradrenaline; Prostate; Sexual activity; Sympathetic innervation; Sympathetic nervous system; Thyroid hormones

Indexed keywords

DEIODINASE TYPE 1; LIOTHYRONINE; NORADRENALIN; ORNITHINE DECARBOXYLASE; OXIDOREDUCTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EJACULATION; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROSTATE; RAT; SYMPATHECTOMY; SYMPATHETIC INNERVATION;

ADRENERGIC FIBERS; ANIMALS; COPULATION; EJACULATION; MALE; PROSTATE; RATS; RATS, WISTAR; TRIIODOTHYRONINE;

ANIMALIA; RATTUS;

EID: 78651515405     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.110.086116     Document Type: Article

References (52)

1. Silva JE, Bianco SDC. Thyroid-adrenergic interactions: Physiological and clinical implications. Thyroid 2008; 18:57-165.
2. Nakao N, Ono H, Yoshimura T. Thyroid hormones and reproductive neuroendocrine interactions. Reproduction 2008; 136:1-8.
3. Stephanick ML, Smith ER, Szumowski DA, Davidson JM. Reproductive physiology and behavior in the male rat following acute and chronic peripheral adrenergic depletion by guanethidine. Pharmacol Biochem Behav 1985; 23:55-63.
4. Jänig W. The integrative action of the autonomic nervous system. In: Neurobiology of Homeostasis. Cambridge: Cambridge University Press; 2006:360-362.
5. Stetchell BE, Maddocks S, Brooks DE. Anatomy, vasculature, innervation and fluids of the male reproductive tract. In: Knobil E, Neill J (eds.), The Physiology of Reproduction, vol. 1, 2nd ed. New York: Raven Press; 1998:1083-1085.
6. Pozuelo JM, Rodríguez R. Innervation of the rat prostate. In: Santamaría L, Ingelmo I, Alonso L, Pozuelo JM, Rodríguez R (eds.), Neuroendocrine Cells and Peptidergic Innervation in Human and Rat Prostate. Advances in Anatomy, Embryology and Cell Biology 194. Madrid: Springer; 2007:51-53.
7. McVary KT, McKenna KE, Lee C. Prostate innervation. Prostate Suppl 1998; 8:2-13.
8. Pennefather JN, Lau WAK, Mitchelson F, Ventura S. The autonomic and sensory innervation of the smooth muscle of the prostate gland: A review of pharmacological and histological studies. J Auton Pharmacol 2000; 20: 193-206.
9. McVary K, Razzaq A, Lee C, Venegas M, Rademaker A, McKenna K. Growth of the rat prostate gland is facilitated by the autonomic nervous system. Biol Reprod 1994; 51:99-107.
10. Wang JM, McKenna KE, Lee C. Determination of prostatic secretion in rats: Effect of neurotransmitters and testosterone. Prostate 1991; 18:289-301.
11. Witte LP, Chapple CR, de la Rosette JJ, Michel MC. Cholinergic innervation and muscarinic receptors in the human prostate. Eur Urol 2008; 54:326-334.
12. Sidharthan V, Rajalingam R, Aruldhas MM, Govindarajulu P. Ventral prostatic phosphomonoesterases and adenosine triphosphatases in hypoand hyperthyroid albino rats. Indian J Exp Biol 1993; 31:414-416.
13. Sidharthan V, Rose PJ, Rajalingam R, Udhayakumar RC, Aruldhas MM, Govindarajulu P. Dorsolateral prostatic phosphomonoesterases and adenosine triphosphatases in hypo- and hyperthyroid rats. Indian J Exp Biol 1994; 32:616-618.
14. Maran RR, Aruldhas MM, Udhayakumar RC, Subramanian S, Rajendiran G, Antony FF, Arunakaran J, Govindarajulu P. Impact of altered thyroid hormone status on prostatic glycosidases. Int J Androl 1998; 21:121-128.
15. Maran RR, Senthilkumaran B, Udhayakumar RC, Arunakaran J, Aruldhas MM. Thyroidectomy modulates rat prostatic monosaccharides. Int J Androl 2000; 23:156-162.
16. St. Germain DL, Galton VA, Hernández A. Minireview: Defining the roles of the iodothyronine deiodinases: Current concepts and challenges. Endocrinology 2009; 150:1097-1107.
17. Anguiano B, López A, Delgado G, Romero C, Aceves C. Deiodinase type 1 activity is expressed in the prostate of pubescent rats and is modulated by thyroid hormones, prolactin and sex hormones. J Endocrinol 2006; 190: 363-371.
18. Anguiano B, Aranda N, Delgado G, Aceves C. Epididymis expresses the highest 50deiodinase activity in the male reproductive system: Kinetic characterization, distribution, and hormonal regulation. Endocrinology 2008; 149:4209-4217.
19. López-Juárez A, Delgado G, Aceves A, Anguiano B. Type 1 deiodinase activity and generation of triiodothyronine (T3) in prostate of sexually active rats. Prostate 2009; 69:1651-1659.
20. Allard J, Truitt WA, McKenna KE, Coolen LM. Spinal control of ejaculation. World J Urol 2005; 23:119-126.
21. Coolen LM. Neural control of ejaculation. J Comp Neurol 2005; 493:39-45.
22. Aceves C, Rojas-Huidobro R, Marina N, Morales MT, Mena F. Mammary gland sympathetic innervation is a major component in type 1 deiodinase regulation. Endocrine 1999; 11:115-121.
23. Aceves C, Rojas-Huidobro R. Effect of suckling stimulation on peripheral deiodination in lactating rats: Differential expression of type 1 deiodinase mRNA forms. J Endocrinol 2001; 171:533-540.
24. Larsson K, Swedin G. The sexual behavior of male rats after bilateral section of the hypogastric nerve and removal of accessory genital glands. Physiol Behav 1971; 6:251-253.
25. Hull EM, Dominguez JM. Sexual behavior in male rodents. Horm Behav 2007; 52:45-55.
26. Meisel RL, Sachs BD. The physiology of male sexual behavior. In: Knobil E, Neill J (eds.), The Physiology of Reproduction, vol. 1, 2nd ed. New York: Raven Press; 1994:8-9.
27. Livak KJ, Smittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)). Methods 2001; 25:402-408.
28. McKeehan WL, Adams PS, Rosser MP. Direct mitogenic effects of insulin, epidermal growth factor, glucocorticoid, cholera toxin, unknown pituitary factors and possibly prolactin, but not androgen, on normal rat prostate epithelial cells in serum-free, primary cell culture. Cancer Res 1984; 44:1998-2010.
29. Maia AL, Berry MJ, Sabbag R, Harney JW, Larsen PR. Structural and functional differences in the dio 1 gene in mice with inherited type 1 deiodinase deficiency. Mol Endocrinol 1995; 9:969-980.
30. Keast JR. Visualization and immunohistochemical characterization of sympathetic and parasympathetic neurons in the rat major pelvic ganglion. Neuroscience 1995; 66:655-662.
31. Molinero P, Guerrero JM. Vasoactive intestinal peptide stimulates type II thyroxine 50-deiodinase and N-acetyltransferase activities in dispersed pineal cells of euthyroid and hypothyroid rats. Neurosci Lett 1993; 19: 130-133.
32. Retana-Márquez S, Bonilla-Jaime H, Velázquez-Moctezuma J. Lack of effect of corticosterone administration on sexual behavior of rats. Physiol Behav 1998; 63:367-370.
33. Hernández ME, Soto-Cid A, Rojas F, Pascual LI, Aranda-Abreu GE, Toledo R, García LI, Quintanar-Stephano A, Manzo J. Prostate response to prolactin in sexually active male rats. Reprod Biol Endocrinol 2006; 4:28.
34. Hernández ME, Soto-Cid A, Aranda-Abreu GE, Díaz R, Rojas F, García LI, Toledo R, Manzo J. A study of the prostate, androgens and sexual activity of male rats. Reprod Biol Endocrinol 2007; 5:11.
35. Pekary AE, Berg L, Santini F, Chopra I, Hershman JM. Cytokines modulate type I iodothyronine deiodinase mRNA levels and enzyme activity in FRTL-5 rat thyroid cells. Mol Cell Endocrinol 1994; 101:31-35.
36. Gereben B, Goncalves C, Harney J, Larsen PR, Bianco A. Selective proteolysis of human type 2 deiodinase: A novel ubiquitin-proteasomal mediated mechanism of regulation of hormone action. Mol Endocrinol 2000; 14:1697-1708.
37. Groos S, Wilhelm B, Renneberg H, Riva A, Reichelt R, Seitz J, Aumüller G. Simultaneous apocrine and merocrine secretion in the rat coagulating gland. Cell Tissue Res 1999; 295:495-504.
38. Seitz J, Keppler C, Rausch U, Aumüller G. Immunohistochemistry of secretory transglutaminase from rodent prostate. Histochemistry 1990; 93: 525-530.
39. Aceves C, Rodón Fonte C, Ramírez-C I, Wilson S, Pineda-C O, Lopez-B L, Mancilla R, Valverde C. Mammary 50deiodinase (50D) during the breeding cycle of the rat: Indirect evidence that 50D type 1 is specific to the alveolar epithelium. Endocrine 1995; 3:95-99.
40. Sterling K, Brenner MA, Saldhana VF. Conversion of thyroxine by cultured human cells. Science 1973; 179:1000-1001.
41. Leonard JL, Ekenbarger DM, Frank SJ, Farwell AP, Koehrle J. Localization of type 1 iodothyronine 50deiodinase to the basolateral plasma membrane of rat kidney and LLC-PK1 renal cortical cells. J Biol Chem 1991; 266:11262-11269.
42. Borges M, Ingbar SH, Silva JE. Iodothyronine deiodinase activities in FRTL-5 cells: Predominance of type 1 50deiodinase. Endocrinology 1990; 126:3059-3068.
43. Miller LD, Kyung SP, Qingbim MG, Nawal WA, Malek RL, Lee NH, Liu ET, Cheng SY. Silencing of Wnt signaling and activation of multiple metabolic pathways in response to thyroid hormone-stimulated cell proliferation. Mol Cell Biol 2001; 21:6626-6639.
44. Palavan-Unsal N, Aloglu-Senturk SM, Arsan D. The function of polyamine metabolism in prostate cancer. Exp Oncol 2006; 28:178-186.
45. Braun BE, Krieg M. Sexual activity influences organ weight and androgen metabolism of rat prostate, bulbocavernosus/levator ani muscle and kidney. J Steroid Biochem 1983; 19:1763-1768.
46. Aumuller G, Braun BE, Seitz J, Müller T, Heyns W, Krieg M. Effects of sexual rest or sexual activity on the structure and function of the ventral prostate of the rat. Anat Rec 1985; 312:345-352.
47. Aceves C, Valverde C. Type I, 50-monodeiodinase activity in the lactating mammary gland. Endocrinology 1989; 124:2818-2820.
48. Aceves C, Escobar C, Rojas-Huidobro R, Vázquez-Martínez O, Martínez- Merlos T, Aguilar-Roblero R, Díaz M. Liver 50-deiodinase activity is modified in rats under restricted feeding schedules: Evidence for translational regulation. J Endocrinol 2003; 179:91-96.
49. Zhang S, Hsieh M, Zhu W, Klee G, Tindall DJ, Young C. Interactive effects of triiodothyronine and androgens on prostate cell growth and gene expression. Endocrinology 1999; 140:1665-1671.
50. Hsieh ML, Juang HH. Cell growth effects of triiodothyronine and expression of thyroid hormone receptor in prostate carcinoma cells. J Androl 2005; 26:422-428.
51. Rao J, Yang J, Liu Z, Wang L, Yin Z, Liu L, He Q, Yang L. Hypothetic association between greater sympathetic activity and prostate cancer. Med Hypotheses 2008; 71:442-443.
52. Rossato Silva D, Basso Gazzana M, John AB, Rodrigues Siqueira D, Maia AL, Menna Barreto SS. Pulmonary arterial hypertension and thyroid disease. J Bras Pneumol 2009; 35:179-185.