Assessment of carotenoid production by Dunaliella salina in different culture systems and operation regimes

Journal of Biotechnology

Volumn 151, Issue 2, 2011, Pages 180-185

  Prieto, Ana ^a   Pedro Canavate J ^a   García González, Mercedes ^b  

^a IFAPA CENTRO EL TORUÑO   (Spain)

^b CSIC   (Spain)

Author keywords

Carotene; Biotechnology; Dunaliella salina; Microalgae; Outdoor culture; Photobioreactor

Indexed keywords

CAROTENE ISOMERS; CAROTENOID PRODUCTION; CLOSED REACTOR; CULTURE SYSTEMS; DRY WEIGHT; DUNALIELLA; DUNALIELLA SALINA; HALOTOLERANT; MICRO-ALGAE; OPERATION REGIME; OPERATION STRATEGY; OUTDOOR CULTURE; PHOTOBIORE-ACTOR; SEMI-CONTINUOUS; TOTAL CAROTENOIDS; TUBULAR PHOTOBIOREACTOR; TWO STAGE;

ALGAE; BIOTECHNOLOGY; MICROORGANISMS;

PIGMENTS;

9 CIS BETA CAROTENE; BETA CAROTENE; CAROTENOID; UNCLASSIFIED DRUG;

ALGA; ARTICLE; DUNALIELLA SALINA; NONHUMAN; PHOTOBIOREACTOR; PRIORITY JOURNAL;

BETA CAROTENE; BIOREACTORS; BIOTECHNOLOGY; CAROTENOIDS; CHLOROPHYTA; CULTURE MEDIA; ISOMERISM; LIGHT; LUTEIN; PHOTOBIOREACTORS; PHOTOCHEMISTRY; PROTEIN ISOFORMS; TEMPERATURE;

ALGAE; DUNALIELLA; DUNALIELLA SALINA;

EID: 78651497865     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2010.11.011     Document Type: Article

References (31)

1. Becker E.W. Microalgae: Biotechnology and Microbiology 1994, Cambridge University Press, Cambridge, pp. 293.
2. Ben-Amotz A. New mode of Dunaliella biotechnology: two-phase growth for β-carotene production. J. Appl. Phycol. 1995, 7:65-68.
3. Ben-Amotz A. Dunaliella β-carotene: from science to commerce. Enigmatic Microorganisms and Life in Extreme Environments 1999, 401-410. Kluwer Academic Publisher, The Netherlands. J. Seckbach (Ed.).
4. Ben-Amotz A. Bioactive compounds: glycerol production, carotenoid production, fatty acids production. The Alga Dunaliella, Biodiversity, Physiology, Genomics and Biotechnology 2009, 189-208. Science Publishers, Enfield, USA. A. Ben-Amotz, J.E.W. Polle, D.V. Subba Rao (Eds.).
5. Ben-Amotz A., Avron M. On the factors which determine the massive β-carotene accumulation in the halotolerant alga Dunaliella bardawil. Plant Physiol. 1983, 72:593-597.
6. Ben-Amotz A., Shaish A. β-Carotene bio-synthesis. Dunaliella: Physiology, Biochemistry and Biotechnology 1992, 206-216. CRC Press, Boca Raton, FL. M. Avron, A. Ben-Amotz (Eds.).
7. Ben-Amotz A., Lers A., Avron M. Stereoisomers of β-carotene and phytoene in the alga Dunaliella bardawil. Plant Physiol. 1988, 186:1286-1291.
8. Borowitzka L. Commercial Dunaliella production: history of development. Profiles on Biotechnology 1992, 233-245. Universidade de Santiago, A Coruña, Spain. T.G. Villa, J. Abalde (Eds.).
9. Borowitzka M.A. Microalgae as sources of pharmaceuticals and other biologically active compounds. J. Appl. Phycol. 1995, 7:3-15.
10. Borowitzka M.A. Commercial production of microalgae:ponds, tubes and fermenters. J. Biotechnol. 1999, 70:313-321.
11. Borowitzka M.A., Borowitzka L.J. Dunaliella. Micro-algal Biotechnology 1988, 27-58. Cambridge University Press, Cambridge, UK. M.A. Borowitzka, L.J. Borowitzka (Eds.).
12. Del Campo J.A., Rodriguez H., Moreno J., Vargas M.A., Rivas J., Guerrero M.G. Lutein production by Muriellopsis sp. in an outdoor tubular photobioreactor. J. Biotechnol. 2001, 85:289-295.
13. Del Campo J.A., García-González M., Guerrero M.G. Outdoor cultivation of microalgae for carotenoid production: current state and perspectives. Appl. Microbiol. Biotechnol. 2007, 74:1163-1174.
14. Edge R., McGarvey D.J., Truscott T.G. The carotenoids as antioxidants, a review. J. Photochem. Photobiol. 1997, 41:189-200.
15. García-González M., Moreno J., Manzano J.C., Florencio F.J., Guerrero M.G. Production of Dunaliella salina biomass rich in 9-cis-β-carotene and lutein in a closed tubular photobioreactor. J. Biotechnol. 2005, 115:81-90.
16. Gómez P., González M. The effect of temperature and irradiance on the growth and carotenogenic capacity of seven strains of Dunaliella salina (Chlorophyta) cultivated under laboratory conditions. Biol. Res. 2005, 38:151-162.
17. Guillard R.R.L., Ryther J.H. Studies of marine plankton diatoms. J. Microbiol. 1962, 8:229-239.
18. Hejazi M.A., Anddrysiewicz E., Tramper J., Wijffels R.H. Effect of mixing rate on β-carotene production and extraction by Dunaliella salina in two-phase bioreactor. Biotecnhol. Bioeng. 2003, 84:591-596.
19. Jiménez C., Pick U. Differential stereoisomer compositions of β-carotene in thylakoids and in pigments globules in Dunaliella. J. Plant Physiol. 1994, 143:257-263.
20. Johnson E.A., Schroeder W.A. Advances in Biochemical Engineering Biotechnology 1995, vol. 53:119-178. Springer-Verlag, Berlin.
21. Lee Y.K. Microalgal mass culture systems and methods: their limitation and potential. J. Appl. Phycol. 2001, 13:307-315.
22. Liu Q., Suzuki K., Nakaji S., Sugawara K. Antioxidant activities of natural 9-cis and synthetic all-trans β-carotene assessed by human neutrophil chemiluminescence. Nutr. Res. 2000, 20:5-14.
23. Orset S., Young A. Exposure to low irradiances favors the synthesis of 9-cis-β-carotene in Dunaliella salina (Teod.). Plant Physiol. 2000, 122:609-617.
24. Palozza P., Krinsky N.I. Antioxidant effects of carotenoids in vivo and in vitro: an overview. Methods Enzymol. 1992, 213:403-420.
25. Phillips L.G., Cowan A.K., Rose P.D., Logie M.R.R. Operation of the xanthophylls cycle in non-stress and stressed cells of Dunaliella salina in response to diurnal changes in incident irradiation: a correlation with intracellular β-carotene content. J. Plant Physiol. 1995, 146:547-553.
26. Richmond A. Large-scale microalgal culture and applications. Progress in Phycological Research 1991, Biopress Ltd., Bristol, England, pp. 1-62. Round, Chapman (Eds.).
27. Richmond A., Boussiba S., Vonshak A., Kopel R. A new tubular reactor for mass production of microalgae outdoors. J. Appl. Phycol. 1993, 5:327-332.
28. Shaish A., Ben-Amotz A., Avron M. Biosynthesis of β-carotene in Dunaliella. Methods Enzymol. 1992, 213:439-444.
29. Tredici M.R. Mass production of microalgae: photobioreactors. Handbook of Microalgal Culture: Biotechnology and Applied Phycology 2004, 178-214. Blackwell, Oxford, UK.
30. Tredici M.R., Zitelli G.C. Cultivation of Spirulina (Arthrospira) platensis in flat plate reactor. Spirulina platensis (Arthrospira)- Physiology, Cell Biology and Biotechnology 1997, Tailor and Francis, London, U.K., pp. 117-130. A. Vonshak (Ed.).
31. Wijffels R.H., Barbosa M., Jansen M. Cultivation of Dunaliella for high value compounds. The Alga Dunaliella, Biodiversity, Physiology, Genomics and Biotechnology 2009, 91-110. Science Publishers, Enfield, USA. A. Ben-Amotz, J.E.W. Polle, D.V. Subba Rao (Eds.).