Overlapping spatiotemporal patterns of regulatory gene expression are required for neuronal progenitors to specify retinal ganglion cell fate

Vision Research

Volumn 51, Issue 2, 2011, Pages 251-259

  Kiyama, Takae ^a   Mao, Chai An ^a   Cho, Jang Hyeon ^a   Fu, Xueyao ^a   Pan, Ping ^a   Mu, Xiuqian ^a   Klein, William H ^a,b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

Cell cycle; Homeobox factor Pax6; Neurod1; Proneural bHLH factors Atoh7; Retinal development; Retinal ganglion cells; Retinal progenitor cells

Indexed keywords

LIM PROTEIN; NEUROGENIC DIFFERENTIATION FACTOR; TRANSCRIPTION FACTOR POU4F2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATOH7 GENE; CELL FATE; CELL SPECIFICITY; CELL SUBPOPULATION; CELL TYPE; CONTROLLED STUDY; EMBRYO; GENE; GENE EXPRESSION REGULATION; KNOCKOUT MOUSE; MITOSIS; MOUSE; NERVE CELL DIFFERENTIATION; NERVE DEGENERATION; NEURAL STEM CELL; NEUROD1 GENE; NONHUMAN; OPTIC NERVE DISEASE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RETINA DEVELOPMENT; RETINA GANGLION CELL;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IMMUNOHISTOCHEMISTRY; MICE; NERVE TISSUE PROTEINS; RETINA; RETINAL GANGLION CELLS; STEM CELLS;

EID: 78651497579     PISSN: 00426989     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.visres.2010.10.016     Document Type: Article

References (38)

1. Agathocleous M., Harris W.A. From progenitors to differentiated cells in the vertebrate retina. Annual Review of Cell and Developmental Biology 2009, 25:45-69.
2. Brown N.L., Kanekar S., Vetter M.L., Tucker P.K., Gemza D.L., Glaser T. Math5 encodes a murine basic helix-loop-helix transcription factor expressed during early stages of retinal neurogenesis. Development 1998, 125:4821-4833.
3. Brown N.L., Patel S., Brzezinski J., Glaser T. Math5 is required for retinal ganglion cell and optic nerve formation. Development 2001, 128:2497-2508.
4. Burmeister M., Novak J., Liang M.Y., Basu S., Ploder L., Hawes N.L., et al. Ocular retardation mouse caused by Chx10 homeobox-null allele: Impaired retinal progenitor proliferation and bipolar cell differentiation. Nature Genetics 1996, 12:376-384.
5. Chalupa L.M., Williams R.W. Eye, retina, and visual system of the mouse. Development of the mouse eye 2008, The MIT Press, Cambridge, MA, (Chapter IV).
6. Dyer M.A. Regulation of proliferation, cell fate specification and differentiation by the homeodomain proteins, Prox1, Six3, and Chx10 in the developing retina. Cell Cycle 2003, 2:350-357.
7. Fu X., Kiyama T., Li R., Russell M., Klein W.H., Mu X. Epitope-tagging Math5 and Pou4f2: New tools to study retinal ganglion cell development in the mouse. Developmental Dynamics 2009, 238:2309-2317.
8. Gan L., Wang S.W., Huang Z., Klein W.H. POU domain factor Brn-3b is essential for retinal ganglion cell differentiation and survival but not for initial cell fate specification. Developmental Biology 1999, 210:469-480.
9. Hatakeyama J., Kageyama R. Retinal cell fate determination and bHLH factors. Seminars in Cell & Developmental Biology 2004, 15:83-89.
10. Hatakeyama J., Tomita K., Inoue T., Kageyama R. Roles of homeobox and bHLH genes in specification of a retinal cell type. Development 2001, 128:1313-1322.
11. Inoue T., Hojo M., Bessho Y., Tano Y., Lee J.E., Kageyama R. Math3 and NeuroD regulate amacrine cell fate specification in the retina. Development 2002, 129:831-842.
12. Kagalwala M.N., Singh S.K., Majumder S. Stemness is only a state of the cell. Cold Spring Harbor Symposia on Quantitative Biology 2008, 73:227-234.
13. Lamba D., Karl M., Reh T. Neural regeneration and cell replacement: A view from the eye. Cell Stem Cell 2008, 2:538-549.
14. Le T.T., Wroblewski E., Patel S., Riesenberg A.N., Brown N.L. Math5 is required for both early retinal neuron differentiation and cell cycle progression. Developmental Biology 2006, 295:764-778.
15. Liang L., Sandell J.H. Focus on molecules: Homeobox protein Chx10. Experimental Eye Research 2008, 86:541-542.
16. Lin B., Wang S.W., Masland R.H. Retinal ganglion cell type, size, and spacing can be specified independent of homotypic dendritic contacts. Neuron 2004, 43:474-485.
17. Liu H., Etter P., Hayes S., Jones I., Nelson B., Hartman B., et al. NeuroD1 regulates expression of thyroid hormone receptor 2 and cone opsin in the developing mouse retina. Journal of Neuroscience 2008, 28:749-756.
18. Livesey F.J., Cepko C.L. Vertebrate neural cell-fate determination: Lessons from the retina. Nature Reviews Neuroscience 2001, 2:109-118.
19. Mao C.A., Kiyama T., Pan P., Furuta Y., Hadjantonakis A.K., Klein W.H. Eomesodermin, a target gene of Pou4f2, is required for retinal ganglion cell and optic nerve development in the mouse. Development 2008, 135:271-280.
20. Mao, C. A., Tsai, W. W., Barton, M. C., Klein, W. H. (in preparation). Neuronal transcriptional repressor REST suppresses an Atoh7-independent program for initiating retinal ganglion cell development. Developmental Biology.
21. Mao C.A., Wang S.W., Pan P., Klein W.H. Rewiring the retinal ganglion cell gene regulatory network: Neurod1 promotes retinal ganglion cell fate in the absence of Math5. Development 2008, 135:3379-3388.
22. Marquardt T., Ashery-Paden R., Andrejewski N., Scardigli R., Guillemot F., Gruss P. Pax6 is required for the multipotent state of retinal progenitor cells. Cell 2001, 105:43-55.
23. Marquardt T., Gruss P. Generating neuronal diversity in the retina: One for nearly all. Trends in Neurosciences 2002, 25:32-38.
24. Moshiri A., Gonzalez E., Tagawa K., Wang M., Frishman L.J., Wang S.W. Near complete loss of retinal ganglion cells in the math5/brn3b double knockout elicits severe reductions of other cell types during retinal development. Developmental Biology 2008, 316:214-227.
25. Mu X., Fu X., Beremand P.D., Thomas T.L., Klein W.H. Gene regulation logic in retinal ganglion cell development: Isl1 defines a critical branch distinct from but overlapping with Pou4f2. Proceedings of the National Academy of Sciences of the United States of America 2008, 105:6942-6947.
26. Mu X., Fu X., Sun H., Beremand P.D., Thomas T.L., Klein W.H. A gene network downstream of transcription factor Math5 regulates retinal progenitor cell competence and ganglion cell fate. Developmental Biology 2005, 280:467-481.
27. Mu X., Klein W.H. A gene regulatory hierarchy for retinal ganglion cell specification and differentiation. Seminars in Cell & Developmental Biology 2004, 15:115-123.
28. Mu X., Klein W.H. Gene regulatory networks and retinal ganglion cell development. Eye 2008, 321-332. Retina, and Visual System of the Mouse. The MIT Press, Cambridge, MA. L.M. Chalupa, R.W. Williams (Eds.).
29. Ohsawa R., Kageyama R. Regulation of retinal cell fate specification by multiple transcription factors. Brain Research 2008, 4(1192):90-98.
30. Oran-Karni V., Fahy C., Elgart M., Remizova L., Yaron D., Xie Q., et al. Dual requirement for Pax6 in retinal progenitor cell. Development 2008, 135:4037-4047.
31. Pan L., Deng M., Xie X., Gan L. ISL1 and BRN3B co-regulate the differentiation of murine retinal ganglion cells. Development 2008, 135:1981-1990.
32. Pennesi M.E., Cho J.H., Wu S.H., Zhang J., Wu S.M., Tsai M.J. BETA2/NeuroD1 null mice: A new model for transcription factor-dependent photoreceptor degeneration. Journal of Neuroscience 2003, 23:453-461.
33. Riesenberg A.N., Lee T.T., Willardsen M.I., Blackburn D.C., Vetter M.L., Brown N.L. Pax6 regulation of Math5 during mouse retinal neurogenesis. Genesis 2009, 47:175-187.
34. Riesenberg A.N., Liu Z., Kopan R., Brown N.L. RBPJ cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina. Journal of Neuroscience 2009, 29:12865-12877.
35. Vetter M.L., Brown N.L. The role of basic helix-loop-helix genes in vertebrate retinogenesis. Seminars in Cell & Developmental Biology 2001, 12:491-498.
36. Wang S.W., Kim B.S., Ding K., Wang H., Sun D., Johnson R.L., et al. Requirement for math5 in the development of retinal ganglion cells. Genes and Development 2001, 15:24-29.
37. Willardsen M.I., Suli A., Pan Y., Marsh-Armstrong N., Chien C.B., El-Hodiri H., et al. Temporal regulation of Ath5 gene expression during eye development. Developmental Biology 2009, 326:471-481.
38. Yang Z., Ding K., Pan L., Deng M., Gan L. Math5 determines the competence state of retinal ganglion cell progenitors. Developmental Biology 2003, 264:240-254.