Effect of ginger on gastric motility and symptoms of functional dyspepsia

World Journal of Gastroenterology

Volumn 17, Issue 1, 2011, Pages 105-110

  Hu, Ming Luen ^a   Rayner, Christophan K ^b   Wu, Keng Liang ^a   Chuah, Seng Kee ^a   Tai, Wei Chen ^a   Chou, Yeh Pin ^a   Chiu, Yi Chun ^a   Chiu, King Wah ^a   Hu, Tsung Hui ^a  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

Abdominal ultrasound; Antral contraction; Functional dyspepsia; Gastric emptying; Ghrelin; Ginger (Zinger offinale); Glucagon like peptide 1; Motilin

Indexed keywords

GHRELIN; GLUCAGON LIKE PEPTIDE 1; MOTILIN; PLACEBO;

APPETITE; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; DOUBLE BLIND PROCEDURE; DYSPEPSIA; GINGER; HUMAN; QUESTIONNAIRE; STOMACH EMPTYING; STOMACH MOTILITY; SYMPTOM; ULTRASOUND;

EID: 78651483616     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v17.i1.105     Document Type: Article

References (25)

1. Clouse RE, Mayer EA, Aziz Q, Drossman DA, Dumitrascu DL, Mönnikes H, Naliboff BD. Functional abdominal pain syndrome. Gastroenterology 2006; 130: 1492-1497
2. Holtmann G, Talley NJ. Functional dyspepsia. Current treatment recommendations. Drugs 1993; 45: 918-930
3. Talley NJ, McNeil D, Hayden A, Piper DW. Randomized, double-blind, placebo-controlled crossover trial of cimetidine and pirenzepine in nonulcer dyspepsia. Gastroenterology 1986; 91: 149-156
4. Moayyedi P, Delaney BC, Vakil N, Forman D, Talley NJ. The efficacy of proton pump inhibitors in nonulcer dyspepsia: a systematic review and economic analysis. Gastroenterology 2004; 127: 1329-1337
5. Laine L, Schoenfeld P, Fennerty MB. Therapy for Helicobacter pylori in patients with nonulcer dyspepsia. A metaanalysis of randomized, controlled trials. Ann Intern Med 2001; 134: 361-369
6. Johns Cupp M. Toxicology and clinical pharmacology of herbal products. Totowa, New Jersey (USA): Humana Press, 2000: 123-129
7. Capasso F, Gaginella TS, Grandolini G, Izzo AA. Phytotherapy. A quick reference to herbal medicine SpringerVerlag, Heidelberg (Germany), 2003
8. Yamahara J, Huang QR, Li YH, Xu L, Fujimura H. Gastrointestinal motility enhancing effect of ginger and its active constituents. Chem Pharm Bull (Tokyo) 1990; 38: 430-431
9. Micklefield GH, Redeker Y, Meister V, Jung O, Greving I, May B. Effects of ginger on gastroduodenal motility. Int J Clin Pharmacol Ther 1999; 37: 341-346
10. Wu KL, Rayner CK, Chuah SK, Changchien CS, Lu SN, Chiu YC, Chiu KW, Lee CM. Effects of ginger on gastric emptying and motility in healthy humans. Eur J Gastroenterol Hepatol 2008; 20: 436-440
11. Tack J, Depoortere I, Bisschops R, Delporte C, Coulie B, Meulemans A, Janssens J, Peeters T. Influence of ghrelin on interdigestive gastrointestinal motility in humans. Gut 2006; 55: 327-333
12. Luiking YC, Akkermans LM, van der Reijden AC, Peeters TL, van Berge-Henegouwen GP. Differential effects of motilin on interdigestive motility of the human gastric antrum, pylorus, small intestine and gallbladder. Neurogastroenterol Motil 2003; 15: 103-111
13. Wishart JM, Horowitz M, Morris HA, Jones KL, Nauck MA. Relation between gastric emptying of glucose and plasma concentrations of glucagon-like peptide-1. Peptides 1998; 19: 1049-1053
14. Gilja OH, Lunding J, Hausken T, Gregersen H. Gastric accommodation assessed by ultrasonography. World J Gastroenterol 2006; 12: 2825-2829
15. Hausken T, Odegaard S, Berstad A. Antroduodenal motility studied by real-time ultrasonography. Effect of enprostil. Gastroenterology 1991; 100: 59-63
16. Sepple CP, Read NW. Gastrointestinal correlates of the development of hunger in man. Appetite 1989; 13: 183-191
17. Horowitz M, Edelbroek MA, Wishart JM, Straathof JW. Relationship between oral glucose tolerance and gastric emptying in normal healthy subjects. Diabetologia 1993; 36: 857-862
18. Talley NJ, Locke GR 3rd, Lahr BD, Zinsmeister AR, Tougas G, Ligozio G, Rojavin MA, Tack J. Functional dyspepsia, delayed gastric emptying, and impaired quality of life. Gut 2006; 55: 933-939
19. Chen SL, Ji JR, Xu P, Cao ZJ, Mo JZ, Fang JY, Xiao SD. Effect of domperidone therapy on nocturnal dyspeptic symptoms of functional dyspepsia patients. World J Gastroenterol 2010; 16: 613-617
20. Hausken T, Berstad A. Wide gastric antrum in patients with non-ulcer dyspepsia. Effect of cisapride. Scand J Gastroenterol 1992; 27: 427-432
21. Pilichiewicz AN, Feltrin KL, Horowitz M, Holtmann G, Wishart JM, Jones KL, Talley NJ, Feinle-Bisset C. Functional dyspepsia is associated with a greater symptomatic response to fat but not carbohydrate, increased fasting and postprandial CCK, and diminished PYY. Am J Gastroenterol 2008; 103: 2613-2623
22. Lien HC, Sun WM, Chen YH, Kim H, Hasler W, Owyang C. Effects of ginger on motion sickness and gastric slow-wave dysrhythmias induced by circular vection. Am J Physiol Gastrointest Liver Physiol 2003; 284: G481-G489
23. Stadelmann O, Kohler S, Kieser M, Stolte M. Pfefferminzol/ Ingwerextrakt bei funktioneller Dyspepsie. Randomisierte plazebokontrollierte Wirksamkeits und Vertraglichkeitsstudie mit Kombinationspraparat. Leber Magen Darm 1999; 29: 1-8
24. Abdel-Aziz H, Windeck T, Ploch M, Verspohl EJ. Mode of action of gingerols and shogaols on 5-HT3 receptors: binding studies, cation uptake by the receptor channel and contraction of isolated guinea-pig ileum. Eur J Pharmacol 2006; 530: 136-143
25. Shibata C, Sasaki I, Naito H, Ueno T, Matsuno S. The herbal medicine Dai-Kenchu-Tou stimulates upper gut motility through cholinergic and 5-hydroxytryptamine 3 receptors in conscious dogs. Surgery 1999; 126: 918-924