Non-invasive assessment of failure torque in rat bones with simulated lytic lesions using computed tomography based structural rigidity analysis

Journal of Biomechanics

Volumn 44, Issue 3, 2011, Pages 552-556

  Entezari, Vahid ^a   Basto, Pamela A ^b   Vartanians, Vartan ^a   Zurakowski, David ^c   Snyder, Brian D ^a,c   Nazarian, Ara ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Bone; Computed tomography; Dual energy X ray absorptiometry; Fracture risk; Rat; Simulated lytic defects; Structural rigidity

Indexed keywords

COMPUTED TOMOGRAPHY; DUAL ENERGY X-RAY ABSORPTIOMETRY; FRACTURE RISK; SIMULATED LYTIC DEFECTS; STRUCTURAL RIGIDITY;

BONE; COMPUTERIZED TOMOGRAPHY; DEFECTS; LIGHT ABSORPTION; MECHANICAL TESTING; QUALITY ASSURANCE; RATING; RIGIDITY; SILICATE MINERALS; STRUCTURAL ANALYSIS; TORQUE; X RAY ANALYSIS; X RAYS;

FRACTURE;

ACCURACY; ANIMAL TISSUE; ARTICLE; BONE ATROPHY; BONE DENSITY; BONE EXAMINATION; CONTROLLED STUDY; DISEASE MODEL; DUAL ENERGY X RAY ABSORPTIOMETRY; FAILURE TORQUE; FEMALE; INTERMETHOD COMPARISON; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; MECHANICAL STRESS; MICRO-COMPUTED TOMOGRAPHY; MUSCULOSKELETAL SYSTEM PARAMETERS; NON INVASIVE MEASUREMENT; NONHUMAN; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; RIGIDITY; STRUCTURAL RIGIDITY ANALYSIS; THREE DIMENSIONAL IMAGING; ULTRASTRUCTURE;

ANIMALS; BIOMECHANICS; BONE DENSITY; FEMALE; FEMUR; RATS; RATS, SPRAGUE-DAWLEY; TOMOGRAPHY, X-RAY COMPUTED; TORQUE;

EID: 78651456837     PISSN: 00219290     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2010.09.022     Document Type: Article

References (17)

1. Bunting R., et al. Pathologic fracture risk in rehabilitation of patients with bony metastases. Clin. Orthop. Rel. Res. 1985, 192:222-227.
2. Cory E., Nazarian A., Entezari V., Vartanians V., Muller R., Snyder B.D. Compressive axial mechanical properties of rat bone as functions of bone volume fraction, apparent density and micro-ct based mineral density. J. Biomech. 2009, 43:953-960.
3. Cowin S.C. Torsion of cylinders with shape intrinsic orthotropy. Transaction of the ASME: Journal of Applied Mechanics 1987, 54.
4. Dunn O.J., Clark V. Correlation coefficients measured on the same individuals. J. Am. Stat. Assoc. 1969, 64:366-377.
5. Heaney R.P. Is the paradigm shifting?. Bone 2003, 33:457-465.
6. Hong J., Cabe G.D., Tedrow J.R., Hipp J.A., Snyder B.D. Failure of trabecular bone with simulated lytic defects can be predicted non-invasively by structural analysis. J. Orthop. Res. 2004, 22:479-486.
7. Martin R.B. Determinants of the mechanical properties of bones. J. Biomech. 1991, 24(1):79-88.
8. Meng X.W., Rosenthal R., Rubin D.B. Comparing correlated correlation coefficients. Quat. Methods Psychol. 1992, 111:172.
9. Nazarian A., Bauernschmitt M., Eberle C., Meier D., Muller R., Snyder B.D. Design and validation of a testing system to assess torsional cancellous bone failure in conjunction with time-lapsed micro-computed tomographic imaging. J. Biomech. 2008, 41:3496-3501.
10. Nazarian A., Entezari V., Vartanians V., Muller R., Snyder B.D. An improved method to assess torsional properties of rodent long bones. J. Biomech. 2009, 42:1720-1725.
11. Phadke P.A., Mercer R.R., Harms J.F., Jia Y., Frost A.R., Jewell J.L., Bussard K.M., Nelson S., Moore C., Kappes J.C., Gay C.V., Mastro A.M., Welch D.R. Kinetics of metastatic breast cancer cell trafficking in bone. Clin. Cancer Res. 2006, 12:1431-1440.
12. Riggs B.L., Melton L.J. Bone turnover matters: the raloxifene treatment paradox of dramatic decreases in vertebral fractures without commensurate increases in bone density. J. Bone Miner. Res. 2002, 17:11-14.
13. Robertson D., Beck T., Brandon W.C., William W.S., Gulshan B.S., Maloney W.J. Torsional strength estimates of femoral diaphyses with endosteal lytic lesions: dual-energy X-ray absorptiometry study. J. Orthop. Res. 2007, 25:1343-1350.
14. Snyder B.D., Cordio M.A., Nazarian A., Kwak S.D., Chang D.J., Entezari V., Zurakowski D., Parker L.M. Noninvasive prediction of fracture risk in patients with metastatic cancer to the spine. Clin. Cancer Res. 2009, 15:7676-7683.
15. Snyder B.D., Hauser-Kara D.A., Hipp J.A., Zurakowski D., Hecht A.C., Gebhardt M.C. Predicting fracture through benign skeletal lesions with quantitative computed tomography. J. Bone Joint Surg. Am. 2006, 88:55-70.
16. Turner C.H. Determinants of skeletal fragility and bone quality. J. Musculoskelet. Neuronal Interact. 2002, 2:527-528.
17. Whealan K.M., Kwak S.D., Tedrow J.R., Inoue K., Snyder B.D. Noninvasive imaging predicts failure load of the spine with simulated osteolytic defects. J. Bone Joint Surg. Am. 2000, 82:1240-1251.