Postnatal development of the serotonin signaling system in the mucosa of the guinea pig ileum

Neurogastroenterology and Motility

Volumn 23, Issue 2, 2011, Pages

  Zhao, H ^a   Sovadinova, I ^b   Swope, V M ^a   Swain, G M ^a   Kadrofske, M M ^b   Bian, X ^b  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

5 Hydroxytryptamine; Enteric nervous system; Postnatal maturation; Serotonin

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; SEROTONIN; SEROTONIN TRANSPORTER;

AMPEROMETRY; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENTEROCHROMAFFIN CELL; GUINEA PIG; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ILEUM MUCOSA; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; NEWBORN; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SMALL INTESTINE;

AGING; ANIMALS; CELL COUNT; ENTEROCHROMAFFIN CELLS; GUINEA PIGS; HYDROXYINDOLEACETIC ACID; ILEUM; INTESTINAL MUCOSA; MALE; MICROELECTRODES; MODELS, ANIMAL; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SIGNAL TRANSDUCTION;

EID: 78651438618     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/j.1365-2982.2010.01645.x     Document Type: Article

References (35)

1. Mawe GM, Coates MD, Moses PL. Intestinal serotonin signalling in irritable bowel syndrome. Aliment Pharmacol Ther 2006; 23: 1067-76.
2. Bulbring E, Lin RC. The effect of intraluminal application of 5-hydroxytryptamine and 5-hydroxytryptophan on peristalsis; the local production of 5-HT and its release in relation to intraluminal pressure and propulsive activity. J Physiol 1958; 140: 381-407.
3. Kirchgessner AL, Tamir H, Gershon MD. Identification and stimulation by serotonin of intrinsic sensory neurons of the submucosal plexus of the guinea pig gut: activity-induced expression of Fos immunoreactivity. J Neurosci 1992; 12: 235-48.
4. Racké K, Reimann A, Schwörer H, Kilbinger H. Regulation of 5-HT release from enterochromaffin cells. Behav Brain Res 1996; 73: 83-7.
5. Gershon MD. Review article: serotonin receptors and transporters-roles in normal and abnormal gastrointestinal motility. Aliment Pharmacol Ther 2004; 20(Suppl. 7): 3-14.
6. Wade PR, Chen J, Jaffe B, Kassem IS, Blakely RD, Gershon MD. Localization and function of a serotonin transporter in crypt epithelia of the gastrointestinal tract. J Neurosci 1996; 16: 2352-64.
7. Dunlop SP, Coleman NS, Blackshaw E et al. Abnormalities of 5-hydroxytryptamine metabolism in irritable bowel syndrome. Clin Gastroenterol Hepatol 2005; 3: 349-57.
8. Bian X, Patel BA, Dai X, Galligan JJ, Swain GM. High mucosal serotonin availability in neonatal guinea pig ileum is associated with low serotonin transporter expression. Gastroenterology 2007; 132: 2438-47.
9. Coates MD, Mahoney CR, Linden DR et al. Molecular defects in mucosal serotonin content and decreased serotonin reuptake transporter in ulcerative colitis and irritable bowel syndrome. Gastroenterology 2004; 126: 1657-64.
10. Galligan JJ, Parkman H. Recent advances in understanding the role of serotonin in gastrointestinal motility and functional bowel disorders. Neurogastroenterol Motil 2007; 19(Suppl. 2): 1-4.
11. Spiller R. Recent advances in understanding the role of serotonin in gastrointestinal motility in functional bowel disorders: alterations in 5-HT signalling and metabolism in human disease. Neurogastroenterol Motil 2007; 19(Suppl. 2): 25-31.
12. Liu MT, Kuan YH, Wang J, Hen R, Gershon MD. Serotonin4 receptor-mediated neuroprotection and neurogenesis in the enteric nervous system of adult mice. J Neurosci 2009; 29: 9683-99.
13. Bian X, Burda JE, Carrasquillo M, Galligan JJ. Postnatal downregulation of inhibitory neuromuscular transmission to the longitudinal muscle of the guinea pig ileum. Neurogastroenterol Motil 2009; 21: 969-77.
14. Patel BA, Dai X, Burda JE et al. Inhibitory neuromuscular transmission to ileal longitudinal muscle predominates in neonatal guinea pigs. Neurogastroenterol Motil 2010; 22: 909-18.
15. Giaroni C, Knight GE, Zanetti E et al. Postnatal development of P2 receptors in the murine gastrointestinal tract. Neuropharmacology 2006; 50: 690-704.
16. Gershon MD, Thompson EB. The maturation of neuromuscular function in a multiply innervated structure: development of the longitudinal smooth muscle of the foetal mammalian gut and its cholinergic excitatory, adrenergic inhibitory, and non-adrenergic inhibitory innervation. J Physiol 1973; 234: 257-77.
17. Liem O, Harman J, Benninga M, Kelleher K, Mousa H, Di Lorenzo C. Health utilization and cost impact of childhood constipation in the United States. J Pediatr 2009; 154: 258-62.
18. Saps M, Seshadri R, Sztainberg M, Schaffer G, Marshall BM, Di Lorenzo C. A prospective school-based study of abdominal pain and other common somatic complaints in children. J Pediatr 2009; 154: 322-6.
19. Cvacka J, Quaiserová V, Park J, Show Y, Muck A Jr, Swain GM. Boron-doped diamond microelectrodes for use in capillary electrophoresis with electrochemical detection. Anal Chem 2003; 75: 2678-87.
20. Zhao H, Bian X, Galligan JJ, Swain GM. Electrochemical measurements of serotonin (serotonin) release from the guinea pig mucosa using continuous amperometry with a boron-doped diamond microelectrode. Diam Relat Mater 2010; 19: 182-5.
21. Patel BA, Bian X, Galligan JJ, Swain GM. In vitro continuous amperometric monitoring of 5-hydroxytryptamine release from enterochromaffin cells of the guinea pig ileum. Analyst 2007; 132: 41-7.
22. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951; 193: 265.
23. Marcelli G, Patel BA. Theoretical modelling to understand the neurotransmission mechanism in the gastrointestinal tract. Conf Proc IEEE Eng Med Biol Soc 2008; 2008: 5548-51.
24. Henning SJ. Postnatal development: coordination of feeding, digestion, and metabolism. Am J Physiol 1981; 241: G199-214.
25. Schafer KH, Hansgen A, Mestres P. Morphological changes of the myenteric plexus during early postnatal development of the rat. Anat Rec 1999; 256: 20-8.
26. Bailey M, Haverson K, Inman C et al. The development of the mucosal immune system pre- and post-weaning: balancing regulatory and effector function. Proc Nutr Soc 2005; 64: 451-7.
27. Perez PF, Doré J, Leclerc M et al. Bacterial imprinting of the neonatal immune system: lessons from maternal cells? Pediatrics 2007; 119: 724-32.
28. Bertrand PP. Real-time detection of serotonin release from enterochromaffin cells of the guinea-pig ileum. Neurogastroenterol Motil 2004; 16: 511-4.
29. Bertrand PP. Real-time measurement of serotonin release and motility in guinea pig ileum. J Physiol 2006; 577(Pt 2): 689-704.
30. Geldof M, Freijer JI, Peletier LA, van Beijsterveldt L, Danhof M. Mechanistic model for the acute effect of fluvoxamine on 5-HT and 5-HIAA concentrations in rat frontal cortex. Eur J Pharm Sci 2008; 33: 217-29.
31. Chamba A, Holder MJ, Barnes NM, Gordon J. Characterisation of the endogenous human peripheral serotonin transporter SLCA4 reveals surface expression without N-glycosylation. J Neuroimmunol 2008; 204: 75-84.
32. Coers W, Timens W, Kempinga C, Klok PA, Moshage H. Specificity of antibodies to nitric oxide synthase isoforms in human, guinea pig, rat, and mouse tissues. J Histochem Cytochem 1998; 46: 1385-92.
33. Furness JB. The Enteric Nervous System, 1st edn. Oxford, UK: Blackwell Publishing, 2006.
34. Chen JJ, Li Z, Pan H et al. Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: abnormal intestinal motility and the expression of cation transporters. J Neurosci 2001; 21: 6348-61.
35. Baganz NL, Horton RE, Calderon AS et al. Organic cation transporter 3: keeping the brake on extracellular serotonin in serotonin-transporter-deficient mice. Proc Natl Acad Sci USA 2008; 105: 18976-81.