Effects of aging and hypertension on cerebral ischemic susceptibility: Evidenced by MR diffusion-perfusion study in rat

Experimental Neurology

Volumn 227, Issue 2, 2011, Pages 314-321

  Lee, Tsong Hai ^a   Liu, Ho Ling ^a   Yang, Shun Tai ^b   Yang, Jen Tsung ^a   Yeh, Mei Yu ^a   Lin, Jr Rung ^c  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

Aging; Blood pressure; Cerebral ischemia; Magnetic resonance imaging

Indexed keywords

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD FLOW; BRAIN ISCHEMIA; BRAIN TISSUE; CAROTID ARTERY OBSTRUCTION; COMMON CAROTID ARTERY; CONTROLLED STUDY; DIFFUSION COEFFICIENT; DIFFUSION WEIGHTED IMAGING; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; HIPPOCAMPUS; HYPERTENSION; IMAGE ANALYSIS; MALE; NEUROIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PARIETAL CORTEX; PRIORITY JOURNAL; RAT; RISK ASSESSMENT; RISK FACTOR; SPONTANEOUSLY HYPERTENSIVE RAT; THALAMUS; WISTAR KYOTO RAT;

AGING; ANIMALS; BRAIN ISCHEMIA; DIFFUSION MAGNETIC RESONANCE IMAGING; DISEASE SUSCEPTIBILITY; EVIDENCE-BASED MEDICINE; HYPERTENSION; MAGNETIC RESONANCE ANGIOGRAPHY; MALE; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RISK FACTORS;

EID: 78651421227     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2010.12.003     Document Type: Article

References (41)

1. Abe O., Aoki S., Hayashi N., Yamada H., Kunimatsu A., Mori H., Yoshikawa T., Okubo T., Ohtomo K. Normal aging in the central nervous system: quantitative MR diffusion-tensor analysis. Neurobiol. Aging 2002, 23:433-441.
2. Ajmani R.S., Metter E.J., Jaykumar R., Ingram D.K., Spangler E.L., Abugo O.O., Rifkind J.M. Hemodynamic changes during aging associated with cerebral blood flow and impaired cognitive function. Neurobiol. Aging 2000, 21:257-269.
3. Avsaroglu H., van der Sar A.S., van Lith H.A., van Zutphen L.F., Hellebrekers L.J. Differences in response to anaesthetics and analgesics between inbred rat strains. Lab Anim. 2007, 41:337-344.
4. Ay H., Koroshetz W.J., Vangel M., Benner T., Melinosky C., Zhu M., Menezes N., Lopez C.J., Sorensen A.G. Conversion of ischemic brain tissue into infarction increases with age. Stroke 2005, 36:2632-2636.
5. Camara E., Bodammer N., Rodriguez-Fornells A., Tempelmann C. Age-related water diffusion changes in human brain: a voxel-based approach. Neuroimage 2007, 34:1588-1599.
6. Canese R., Lorenzini P., Fortuna S., Volpe M.T., Giannini M., Podo F., Michalek H. Age-dependent MRI-detected lesions at early stages of transient global ischemia in rat brain. Magma 2004, 17:109-116.
7. Chen Z.G., Li T.Q., Hindmarsh T. Diffusion tensor trace mapping in normal adult brain using single-shot EPI technique. A methodological study aging brain. Acta Radiol. 2001, 42:447-458.
8. Chobanian A.V., Bakris G.L., Black H.R., Cushman W.C., Green L.A., Izzo J.L., Jones D.W., Materson B.J., Oparil S., Wright J.T., Roccella E.J. The seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure: the JNC 7 report. JAMA 2003, 289:2560-2572.
9. Chun T., Filippi C.G., Zimmerman R.D., Ulug A.M. Diffusion changes in the aging human brain. AJNR Am. J. Neuroradiol. 2000, 21:1078-1083.
10. Claus J.J., Breteler M.M., Hasan D., Krenning E.P., Bots M.L., Grobbee D.E., Van Swieten J.C., van Harskamp F., Hofman A. Regional cerebral blood flow and cerebrovascular risk factors in the elderly population. Neurobiol. Aging 1998, 19:57-64.
11. Clozel J.P., Kuhn H., Hefti F. Effects of cilazapril on the cerebral circulation in spontaneously hypertensive rats. Hypertension 1989, 14:645-651.
12. Cohen R.A. Hypertension and cerebral blood flow: implications for the development of vascular cognitive impairment in the elderly. Stroke 2007, 38:1715-1717.
13. Danker J.F., Duong T.Q. Quantitative regional cerebral blood flow MRI of animal model of attention-deficit/hyperactivity disorder. Brain Res. 2007, 1150:217-224.
14. Engelter S.T., Provenzale J.M., Petrella J.R., Delong D.M., MacFall J.R. The effect of aging on the apparent diffusion coefficient of normal-appearing white matter. AJR Am. J. Roentgenol. 2000, 175:425-430.
15. Farkas E., Luiten P.G., Bari F. Permanent, bilateral common carotid artery occlusion in the rat: a model for chronic cerebral hypoperfusion-related neurodegenerative diseases. Brain Res. Rev. 2007, 54:162-180.
16. Fisher M., Albers G.W. Applications of diffusion-perfusion magnetic resonance imaging in acute ischemic stroke. Neurology 1999, 52:1750-1756.
17. Fujishima M., Ishitsuka T., Nakatomi Y., Tamaki K., Omae T. Changes in local cerebral blood flow following bilateral carotid occlusion in spontaneously hypertensive and normotensive rats. Stroke 1981, 12:874-876.
18. Fujishima M., Ibayashi S., Fujii K., Mori S. Cerebral blood flow and brain function in hypertension. Hypertens. Res. 1995, 18:111-117.
19. Fujiwara H., Momoshima S., Kuribayashi S., Sasamura H. Hypertensive encephalopathy of brain stem with minimal supratentorial involvement: a rare manifestation of hypertensive encephalopathy. Radiat. Med. 2005, 23:504-507.
20. Gideon P., Thomsen C., Henriksen O. Increased self-diffusion of brain water in normal aging. J. Magn. Reson. Imaging 1994, 4:185-188.
21. Goldstein L.B., Adams R., Alberts M.J., Appel L.J., Brass L.M., Bushnell C.D., Culebras A., DeGraba T.J., Gorelick P.B., Guyton J.R., Hart R.G., Howard G., Kelly-Hayes M., Nixon J.V., Sacco R.L. Primary prevention of ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council: cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Council; Clinical Cardiology Council; Nutrition, Physical Activity, and Metabolism Council; and the Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation 2006, 113:e873-e923.
22. Heiland S., Sartor K., Martin E., Bardenheuer H.J., Plaschke K. In vivo monitoring of age-related changes in rat brain using quantitative diffusion magnetic resonance imaging and magnetic resonance relaxometry. Neurosci. Lett. 2002, 334:157-160.
23. Helenius J., Soinne L., Perkio J., Salonen O., Kangasmaki A., Kaste M., Carano R.A., Aronen H.J., Tatlisumak T. Diffusion-weighted MR imaging in normal human brains in various age groups. AJNR Am. J. Neuroradiol. 2002, 23:194-199.
24. Henninger N., Sicard K.M., Schmidt K.F., Bardutzky J., Fisher M. Comparison of ischemic lesion evolution in embolic versus mechanical middle cerebral artery occlusion in Sprague Dawley rats using diffusion and perfusion imaging. Stroke 2006, 37:1283-1287.
25. Katano K., Kakuchi Y., Nakashima A., Nakahama K., Kawano M. Apparent diffusion coefficient map based on diffusion-weighted magnetic resonance imaging is useful in diagnosing the brainstem variant of reversible posterior leukoencephalopathy syndrome with uremia. Clin. Exp. Nephrol. 2010, 14:479-482.
26. Katsuta T. Decreased local cerebral blood flow in young and aged spontaneously hypertensive rats. Fukuoka Igaku Zasshi 1997, 88:65-74.
27. Lee T.H., Yang J.T., Kato H., Wu J.H. Hypertension downregulates the expression of brain-derived neurotrophic factor in the ischemia-vulnerable hippocampal CA1 and cortical areas after carotid artery occlusion. Brain Res. 2006, 1116:31-38.
28. Leliefeld P.H., Gooskens R.H., Braun K.P., Ramos L.M., Uiterwaal C.S., Regli L.P., Tulleken C.A., Kappelle L.J., Hanlo P.W. Longitudinal diffusion-weighted imaging in infants with hydrocephalus: decrease in tissue water diffusion after cerebrospinal fluid diversion. J. Neurosurg. Pediatr. 2009, 4:56-63.
29. Lewington S., Clarke R., Qizilbash N., Peto R., Collins R. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 2002, 360:1903-1913.
30. Neal B., MacMahon S., Chapman N. Effects of ACE inhibitors, calcium antagonists, and other blood-pressure-lowering drugs: results of prospectively designed overviews of randomised trials. Blood pressure lowering treatment trialists collaboration. Lancet 2000, 356:1955-1964.
31. Nusbaum A.O., Tang C.Y., Buchsbaum M.S., Wei T.C., Atlas S.W. Regional and global changes in cerebral diffusion with normal aging. AJNR Am. J. Neuroradiol. 2001, 22:136-142.
32. Perez A., Restrepo L., Kleinman J.T., Barker P., Beauchamp N., Wityk R.J. Patients with diffusion-perfusion mismatch on magnetic resonance imaging 48hours or more after stroke symptom onset: clinical and imaging features. J. Neuroimaging 2006, 16:329-333.
33. Pfefferbaum A., Sullivan E.V. Increased brain white matter diffusivity in normal adult aging: relationship to anisotropy and partial voluming. Magn. Reson. Med. 2003, 49:953-961.
34. Rau P.R., Sellner J., Heiland S., Plaschke K., Schellinger P.D., Meyding-Lamade U.K., Lamade W.R. Apparent diffusion coefficient in the aging mouse brain: a magnetic resonance imaging study. Life Sci. 2006, 78:1175-1180.
35. Rothwell P.M., Coull A.J., Giles M.F., Howard S.C., Silver L.E., Bull L.M., Gutnikov S.A., Edwards P., Mant D., Sackley C.M., Farmer A., Sandercock P.A., Dennis M.S., Warlow C.P., Bamford J.M., Anslow P. Change in stroke incidence, mortality, case-fatality, severity, and risk factors in Oxfordshire, UK from 1981 to 2004 (Oxford Vascular Study). Lancet 2004, 363:1925-1933.
36. Schweinhardt P., Fransson P., Olson L., Spenger C., Andersson J.L. A template for spatial normalisation of MR images of the rat brain. J. Neurosci. Methods 2003, 129:105-113.
37. Shintani S., Hino T., Ishihara S., Mizutani S., Shiigai T. Reversible brainstem hypertensive encephalopathy (RBHE): clinicoradiologic dissociation. Clin. Neurol. Neurosurg. 2008, 110:1047-1053.
38. Sinha S., Misra A., Bal C.S., Gouda N.K., Pandey R.M., Tiwari S. Evaluation of cerebral blood flow by single-photon emission computed tomography in young Asian Indians with hypertension. J. Hum. Hypertens. 2006, 20:143-148.
39. Smith T.L., Hutchins P.M. Anesthetic effects on hemodynamics of spontaneously hypertensive and Wistar-Kyoto rats. Am. J. Physiol. 1980, 238:H539-H544.
40. Sood R., Yang Y., Taheri S., Candelario-Jalil E., Estrada E.Y., Walker E.J., Thompson J., Rosenberg G.A. Increased apparent diffusion coefficients on MRI linked with matrix metalloproteinases and edema in white matter after bilateral carotid artery occlusion in rats. J. Cereb. Blood Flow Metab. 2009, 29:308-316.
41. Tatlisumak T., Li F. Use of diffusion- and perfusion-weighted magnetic resonance imaging in drug development for ischemic stroke. Curr. Drug Targets CNS Neurol. Disord. 2003, 2:131-141.