Chimeric fibronectin matrix mimetic as a functional growth- and migration-promoting adhesive substrate

Biomaterials

Volumn 32, Issue 8, 2011, Pages 2077-2087

  Roy, Daniel C ^a   Wilke Mounts, Susan J ^a   Hocking, Denise C ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

Cell adhesion; Cell proliferation; Extracellular matrix; Fibronectin; Recombinant protein

Indexed keywords

ACTIVE REGIONS; BINDING DOMAIN; CELL FUNCTIONS; CELLULAR ACTIVITIES; CHRONIC WOUNDS; COLLAGEN GELS; DEPENDENT PROCESS; EXTRACELLULAR MATRICES; FIBRONECTIN; FIBRONECTIN FRAGMENTS; FIBRONECTIN MATRIX; FUNCTIONAL INFORMATION; HEPARIN BINDING; INTEGRINS; MIMETICS; NORMAL TISSUE; RECOMBINANT PROTEIN; SITE-SPECIFIC; THERAPEUTIC PROTEIN; TISSUE INJURY; TISSUE REPAIR;

AFFINITY CHROMATOGRAPHY; BIOCHEMICAL ENGINEERING; CELL ADHESION; CELL PROLIFERATION; COLLAGEN; GENETIC ENGINEERING; GROWTH KINETICS; TISSUE; TISSUE ENGINEERING;

ADHESION;

FIBRONECTIN;

AFFINITY CHROMATOGRAPHY; ARTICLE; CELL ADHESION; CELL FUNCTION; CELL GROWTH; CELL LYSATE; CELL MIGRATION; CELL PROLIFERATION; EXTRACELLULAR MATRIX; HUMAN; HUMAN TISSUE; NONHUMAN; PRIORITY JOURNAL; TISSUE INJURY; UPREGULATION;

ADSORPTION; ANIMALS; BIOCOMPATIBLE MATERIALS; CELL ADHESION; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; FIBROBLASTS; FIBRONECTINS; HUMANS; MATERIALS TESTING; MICE; PROTEIN ISOFORMS; RATS; RECOMBINANT PROTEINS; SURFACE PROPERTIES;

EID: 78651418862     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.11.050     Document Type: Article

References (55)

1. Hynes R.O., Yamada K.M. Fibronectins: multifunctional modular glycoproteins. J Cell Biol 1982, 95:369-377.
2. Petersen T.E., Thogersen H.C., Skorstengaard K., Vibe-Pedersen K., Sahl P., Sottrup-Jensen L., et al. Partial primary structure of bovine plasma fibronectin: three types of internal homology. Proc Natl Acad Sci USA 1983, 80:137-141.
3. Bork P., Doolittle R.F. Proposed acquisition of an animal protein domain by bacteria. Proc Natl Acad Sci USA 1992, 89:8990-8994.
4. Leahy D.J., Hendrickson W.A., Ankhil I., Erickson H.P. Structure of a fibronectin type III domain from tenascin phased by MAD analysis of the selenomethionyl protein. Science 1992, 258:987-991.
5. Erickson H.P. Reversible unfolding of fibronectin type III and immunoglobulin domains provides the structural basis for stretch and elasticity of titin and fibronectin. Proc Natl Acad Sci 1994, 91:10114-10118.
6. Oberhauser A.F., Badilla-Fernandez C., Carrion-Vazquez M., Fernandez J.M. The mechanical hierarchies of fibronectin observed with single-molecule AFM. J Mol Biol 2002, 319:433-447.
7. Balaban N.Q., Schwarz U.S., Riveline D., Goichberg P., Tzur G., Sabanay I., et al. Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates. Nat Cell Biol 2001, 3:466-472.
8. Mao Y., Schwarzbauer J.E. Fibronectin fibrillogenesis, a cell-mediated matrix assembly process. Matrix Biol 2005, 24:389-399.
9. Baneyx G., Baugh L., Vogel V. Coexisting conformations of fibronectin in cell culture imaged using fluorescence resonance energy transfer. Proc Natl Acad Sci U S A 2001, 98:14464-14468.
10. Bultmann H., Santas A.J., Peters D.M.P. Fibronectin fibrillogenesis involves the heparin II binding domain of fibronectin. J Biol Chem 1998, 273:2601-2609.
11. Magnusson M., Mosher D.F. Fibronectin: structure, assembly, and cardiovascular implications. Arterio Thromb Vasc Biol 1998, 18:1363-1370.
12. Morla A., Zhang Z., Ruoslahti E. Superfibronectin is a functionally distinct form of fibronectin. Nature 1994, 367:193-196.
13. Sottile J., Hocking D.C., Swiatek P.J. Fibronectin matrix assembly enhances adhesion-dependent cell growth. J Cell Sci 1998, 111:2933-2943.
14. Sechler J.L., Schwarzbauer J.E. Control of cell cycle progression by fibronectin matrix architecture. J Biol Chem 1998, 273:25533-25536.
15. Bourdoulous S., Orend G., MacKenna D.A., Pasqualini R., Ruoslahti E. Fibronectin matrix regulates activation of RHO and CDC42 GTPases and cell cycle progression. J Cell Biol 1998, 143:267-276.
16. Mercurius K.O., Morla A.O. Inhibition of vascular smooth muscle growth by inhibition of fibronectin matrix assembly. Circ Res 1998, 82:548-556.
17. Sechler J.L., Schwarzbauer J.E. Coordinated regulation of fibronectin fibril assembly and actin stress fiber formation. Cell Adhesion Commun 1997, 4:413-424.
18. Hocking D.C., Sottile J., Langenbach K.J. Stimulation of integrin-mediated cell contractility by fibronectin polymerization. J Biol Chem 2000, 275:10673-10682.
19. Gui L., Wojciechowski K., Gildner C.D., Nedelkovska H., Hocking D.C. Identification of the heparin-binding determinants within fibronectin repeat III1: role in cell spreading and growth. J Biol Chem 2006, 281:34816-34825.
20. Sottile J., Hocking D.C., Langenbach K.J. Fibronectin matrix assembly stimulates cell growth by RGD-dependent and -independent mechanisms. J Cell Sci 2000, 113:4287-4299.
21. Hocking D.C., Chang C.H. Fibronectin polymerization regulates small airway epithelial cell migration. Am J Physiol Lung Cell Mol Physiol 2003, 285:L169-L179.
22. Sottile J., Hocking D.C. Fibronectin polymerization regulates the composition and stability of extracellular matrix fibrils and cell-matrix adhesions. Mol Biol Cell 2002, 13:3546-3559.
23. Velling T., Risteli J., Wennerberg K., Mosher D.F., Johansson S. Polymerization of type I and III collagens is dependent on fibronectin and enhanced by integrins alpha 11 beta 1 and alpha 2 beta 1. J Biol Chem 2002, 277:37377-37381.
24. Pereira M., Rybarczyk B.J., Odrljin T.M., Hocking D.C., Sottile J., Simpson-Haidaris P.J. The incorporation of fibrinogen into extracellular matrix is dependent on active assembly of a fibronectin matrix. J Cell Sci 2002, 115:609-617.
25. Sabatier L., Chen D., Fagotto-Kaufmann C., Hubmacher D., McKee M.D., Annis D.S., et al. Fibrillin assembly requires fibronectin. Mol Biol Cell 2009, 20:846-858.
26. Chung C.Y., Zardi L., Erickson H.P. Binding of tenascin-C to soluble fibronectin and matrix fibrils. J Biol Chem 1995, 270:29012-29017.
27. Zhou X., Rowe R.G., Hiraoka N., George J.P., Wirtz D., Mosher D.F., et al. Fibronectin fibrillogenesis regulates three-dimensional neovessel formation. Genes Dev 2008, 22:1231-1243.
28. Hocking D.C., Sottile J.S., Reho T., Fassler R., McKeown-Longo P.J. Inhibition of fibronectin matrix assembly by the heparin-binding domain of vitronectin. J Biol Chem 1999, 274:27257-27264.
29. Hynes R.O. Fibronectins 1990, Springer-Verlag, New York.
30. Roberts C.R. Is asthma a fibrotic disease?. Chest 1995, 107:111S-117S.
31. Stenman S., von Smitten K., Vaheri A. Fibronectin and atherosclerosis. Acta Medica Scandinavia 1980, 642:165-170. (Supplement).
32. Hocking D.C., Kowalski K. A cryptic fragment from fibronectin's III-1 module localizes to lipid rafts and stimulates cell growth and contractility. J Cell Biol 2002, 158:175-184.
33. Hocking D.C., Titus P.A., Sumagin R., Sarelius I.H. Extracellular matrix fibronectin mechanically couples skeletal muscle contraction with local vasodilation. Circ Res 2008, 102:372-379.
34. Hocking D.C., Sottile J., McKeown-Longo P.J. Fibronectin's III-1 module contains a conformation-dependent binding site for the amino-terminal region of fibronectin. J Biol Chem 1994, 269:19183-19191.
35. Briknarova K., Akerman M.E., Hoyt D.W., Ruoslahti E., Ely K.R. Anastellin, an FN3 fragment with fibronectin polymerization activity, resembles amyloid fibril precursors. J Mol Biol 2003, 332:205-215.
36. Zhong C., Chrzanowska-Wodnicka M., Brown J., Shaub A., Belkin A.M., Burridge K. Rho-mediated contractility exposes a cryptic site in fibronectin and induces fibronectin matrix assembly. J Cell Biol 1998, 141:539-551.
37. Miekka S.I., Ingham K.C., Menache D. Rapid methods for isolation of human plasma fibronectin. Thromb Res 1982, 27:1-14.
38. Windsor L.J., Havemose-Poulson A., Yamada S., Lyons J.G., Birkedal-Hansen B., Stetler-Stevenson W.G., et al. Matrix metalloproteinases 2002, Wiley & Sons, Inc, New York, NY, p. 10.8.6-10.8.7.
39. Wojciechowski K., Chang C.H., Hocking D.C. Expression, production, and characterization of full-length vitronectin in Escherichia coli. Protein Expr Purif 2004, 36:131-138.
40. Dufour S., Gutman A., Bois F., Lamb N., Thiery J.P., Kornblihtt A.R. Generation of full-length cDNA recombinant vectors for the transient expression of human fibronectin in mammalian cell lines. Exp Cell Res 1991, 193:331-338.
41. Hocking D.C., Sottile J., McKeown-Longo P.J. Activation of distinct α5β1-mediated signaling pathways by fibronectin's cell adhesion and matrix assembly domains. J Cell Biol 1998, 141:241-253.
42. Pierschbacher M., Ruoslahti E. Variants of the cell recognition site of fibronectin that retain attachment-promoting activity. Proc Natl Acad Sci USA 1984, 81:5985-5988.
43. Aota S., Nomizu M., Yamada K.M. The short amino acid sequence Pro-His-Ser-Arg-Asn in human fibronectin enhances cell-adhesive function. J Biol Chem 1994, 269:24756-24761.
44. Main A.L., Harvey T.S., Baron M., Boyd J., Campbell I.D. The three-dimensional structure of the tenth type III module of fibronectin: an insight into RGD-mediated interactions. Cell 1992, 71:671-678.
45. Grinnell F., Lamke C. Reorganization of hydrated collagen lattices by human skin fibroblasts. J Cell Sci 1984, 66:51-63.
46. Garcia A.J., Schwarzbauer J.E., Boettiger D. Distinct activation states of alpha5 beta1 integrin show differential binding to RGD and synergy domains of fibronectin. Biochemistry 2002, 41:9063-9069.
47. Ruoslahti E. RGD and other recognition sequences for integrins. Annu Rev Cell Dev Biol 1996, 12:697-715.
48. Aota S., Nagai T., Yamada K.M. Characterization of regions of fibronectin besides the arginine-glycine-aspartic acid sequence required for adhesive function of the cell-binding domain using site-directed mutagenesis. J Biol Chem 1991, 266:15938-15943.
49. Litvinovich S.V., Novokhatny V.V., Brew S.A., Ingham K.C. Reversible unfolding of an isolated heparin and DNA binding fragment, the first type III module from fibronectin. Biochim Biophys Acta 1992, 1119:57-62.
50. Mercurius K.O., Morla A.O. Cell adhesion and signaling on the fibronectin 1st type III repeat; requisite roles for cell surface proteoglycans and integrins. BMC Cell Biol 2001, 2:18.
51. Bloom L., Calabro V. FN3: a new protein scaffold reaches the clinic. Drug Discov Today 2009, 14:949-955.
52. Litvinovich S.V., Ingham K.C. Interactions between type III domains in the 110 kDa cell-binding fragment of fibronectin. J Mol Biol 1995, 248:611-626.
53. Siggers K., Soto C., Palmer A.G. Conformational dynamics in loop swap mutants of homologous fibronectin type III domains. Biophys J 2007, 93:2447-2456.
54. Billings K.S., Best R.B., Rutherford T.J., Clarke J. Crosstalk between the protein surface and hydrophobic core in a core-swapped fibronectin type III domain. J Mol Biol 2008, 375:560-571.
55. Koide A., Bailey C.W., Huang X., Koide S. The fibronectin type III domain as a scaffold for novel binding proteins. J Mol Biol 1998, 284:1141-1151.