A biomass monitor for disposable bioreactors

BioProcess International

Volumn 9, Issue 1, 2011, Pages 48-54

  Logan, Daniel ^a   Carvell, John ^a  

^a ABER INSTRUMENTS LTD   (United Kingdom)

Author keywords

Bioreactors; Disposables; Monitoring; Probes; Process optimization; Sensors

Indexed keywords

CYCLIC GMP; DISSOLVED OXYGEN;

BIOMASS; BIOMASS FERMENTATION; BIOREACTOR; CELL CULTURE; CELL SUSPENSION; DISPOSABLE EQUIPMENT; ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY; ELECTRODE; MECHANICAL PROBE; MICROBIAL BIOMASS; MONITOR; POLARIZATION; SHORT SURVEY; SOLUTION AND SOLUBILITY; SUSPENSION; YEAST;

EID: 78651406831     PISSN: 15426319     EISSN: None     Source Type: Trade Journal    
DOI: None     Document Type: Short Survey

References (6)

1. Harris CM, et al. The Dielectric Permittivity of Microbial Suspensions at Radio Frequencies: A Novel Method for the Estimation of Microbial Biomass. Enzyme Microb. Technol. 9, 1987: 181-186.
2. Carvell JP, Dowd JE. On-Line Measurement and Control of Viable Cell Density in Cell Culture Manufacturing Processes Using Radio-Frequency Impedance. Cytotechnol. 50, 2006: 35-48.
3. Carvell JP, Taylor S. Advances in Using Capacitance-Based Biomass Probes: Disposable Bioreactors and cGMP (poster). Cell Culture Engineering XII, Banff, Canada, April 2010.
4. Carvell JP, et al. On-Line Monitoring of the Live Cell Concentration in Disposable Bioreactors (poster). European Society for Animal Cell Technology biennial conference, Dublin, Ireland, 7-10 June 2009.
5. Cannizzaro C, et al. On-Line Biomass Monitoring of CHO Perfusion Culture with Scanning Dielectric Spectroscopy. Biotechnol. Bioeng. 84, 2003: 597-610.
6. Marx GH, et al. Recent Developments in Using Scanning Radio-Frequency Impedance Measurements on Cell Culture Processes. BioProcessing J. Winter 2007-2008: 44-47.