Suppression on metastasis by rhubarb through modulation on MMP-2 and uPA in human A549 lung adenocarcinoma: An ex vivo approach

Journal of Ethnopharmacology

Volumn 133, Issue 2, 2011, Pages 426-433

  Shia, Chi Sheng ^a   Suresh, Govindan ^a   Hou, Yu Chi ^a   Lin, Yu Chin ^a   Chao, Pei Dawn Lee ^a   Juang, Shin Hun ^a,b  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Metabolic event; Metastasis; MMP 2; Rhubarb; Traditional Chinese medicine; uPA

Indexed keywords

GELATINASE A; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PLANT MEDICINAL PRODUCT; PROTEIN C JUN; RHUBARB DECOCTION; UNCLASSIFIED DRUG; UROKINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL MOTILITY; CYTOTOXICITY; DOWN REGULATION; ENZYME ACTIVITY; EX VIVO STUDY; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; LUNG METASTASIS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RAT; RHUBARB;

ADENOCARCINOMA; ADMINISTRATION, ORAL; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BASE SEQUENCE; CELL LINE, TUMOR; CELL MOVEMENT; DNA PRIMERS; DOWN-REGULATION; ETHNOPHARMACOLOGY; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LUNG NEOPLASMS; MALE; MATRIX METALLOPROTEINASE 2; MEDICINE, CHINESE TRADITIONAL; MICE; MICE, INBRED NOD; MICE, SCID; NF-KAPPA B; PHYTOTHERAPY; PLANT EXTRACTS; PLANTS, MEDICINAL; RATS; RATS, SPRAGUE-DAWLEY; RHEUM; TAIWAN; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

ANIMALIA; MUS; RATTUS; RHEUM X HYBRIDUM;

EID: 78651400852     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.10.020     Document Type: Article

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