Intracoronary administration of autologous bone marrow mononuclear cells in patients with chronic ischemic symptomatic cardiomyopathy: 5 years follow-up

Israel Medical Association Journal

Volumn 12, Issue 12, 2010, Pages 738-741

  Blatt, Alex ^a   Minha, Sa'ar ^a   Moravsky, Gil ^a   Vered, Zvi ^a   Krakover, Ricardo ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

Autologous intracoronary bone marrow infusion; Cell transplantation; Heart failure; Long term outcome

Indexed keywords

ACUTE CHOLECYSTITIS; ADULT; AGED; ARTICLE; AUTOLOGOUS BONE MARROW TRANSPLANTATION; BALLOON OCCLUSION; CARDIAC RESYNCHRONIZATION THERAPY; CARDIOMYOPATHY; CHRONIC DISEASE; CLINICAL ARTICLE; COMORBIDITY; CONTROLLED STUDY; DEFIBRILLATOR; DISEASE EXACERBATION; ELECTROCARDIOGRAPHY; FEASIBILITY STUDY; FOLLOW UP; HEART FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART MUSCLE ISCHEMIA; HUMAN; INTRACORONARY INFUSION; LABORATORY TEST; LEUKOCYTOCLASTIC VASCULITIS; LUNG EDEMA; LUNG PRESSURE; MALE; MONONUCLEAR CELL; PATIENT SAFETY; PERCUTANEOUS CORONARY INTERVENTION; STRESS ECHOCARDIOGRAPHY; TREATMENT DURATION; TREATMENT INDICATION; TREATMENT OUTCOME;

AGED; AGED, 80 AND OVER; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CHRONIC DISEASE; CORONARY VESSELS; ELECTROCARDIOGRAPHY; ELECTROCARDIOGRAPHY, AMBULATORY; FEASIBILITY STUDIES; FEMALE; FOLLOW-UP STUDIES; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; MYOCARDIAL ISCHEMIA; POSTOPERATIVE COMPLICATIONS; SURVIVAL ANALYSIS; TRANSPLANTATION, AUTOLOGOUS; TREATMENT OUTCOME;

EID: 78651397840     PISSN: 15651088     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Levy D, Kenchaiah S, Larson MG, et al. Long-term trends in the incidence of and survival with heart failure. N Engl J Med 2002; 347: 1397-402.
2. Levy WC, Mozaffarian D, Linker DT, et al. The Seattle heart failure model: prediction of survival in heart failure. Circulation 2006; 113: 1424-33.
3. Caspi O, Gepstein L. Regenerating the heart using human embryonic stem cells-from cell to bedside. IMAJ Isr Med Assoc J 2006; 8: 208-14.
4. Barbash IM, Leor J. Myocardial regeneration by adult stem cells. IMAJ Isr Med Assoc J 2006; 8: 283-7.
5. Taylor DA, Atkins BZ, Hungspreugs P, et al. Regenerating functional myocardium: improve performance after skeletal myoblast transplantation. Nat Med 1998; 4: 929-33.
6. Jain M, DerSimonian H, Brenner DA, et al. Cell therapy attenuates deleterious ventricular remodeling and improves cardiac performance after myocardial infarction. Circulation 2001; 103: 1920-9.
7. Orlic D, Kajstura J, Chimenti S, et al. Bone marrow cells regenerate myocardium. Nature 2001; 410: 701-5.
8. Blatt A, Cotter G, Leitman, et al. Intra-coronary administration of autologous bone marrow mononuclear cells after induction of short ischemia is safe and may improve hibernation and ischemia in patients with ischemic cardiomyopathy. Am Heart J 2005; 150: 986e1-7.
9. Perin EC, Dohmann HF, Borojevic R, et al. Improvement in exercise capacity at six months following transendocardial injection of autologous bone marrow mononuclear cells for ischemic cardiomyopathy. Circulation 2003; 107: R75-83.
10. Assmus B, Schachinger V, Teupe C, et al. Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCAREAMI). Circulation 2002; 106: 3009-17.
11. Yao K, Huang R, Sun A, et al. Repeated autologous bone marrow mononuclear cell therapy in patient with large myocardial infarction. Eur J Heart Fail 2009; 11: 691-8.
12. Moncini D, Staibano M, Mele L, et al. Autologous bone marrow mononuclear cell transplantation in patients undergoing coronary artery by-pass grafting. Am Heart J 2006; 151: 192-7.
13. Wollert KC, Meyer GP, Lotz J, et al. Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomized controlled clinical trial. Lancet 2004; 364: 141-8.
14. Kang HJ, Kim HS, Zhang SY, et al. Effects of intracoronary infusion of peripheral blood stem-cells mobilized with granulocyte-colony stimulating factor on left ventricular systolic function and restenosis after coronary stenting in myocardial infarction: the MAGIC cell randomized clinical trial. Lancet 2004; 363: 751-6.
15. Murry CE, Reinecke H, Pabon LM. Regeneration gaps: observation on stem cells and cardiac repair. J Am Coll Cardiol 2006; 47: 1777-85.
16. Beers SL, Bengel FM, Bartunek J, et al. Role of imaging in cardiac stem cell therapy. J Am Coll Cardiol 2007; 49: 1137-48.
17. Abdel-Latif A, Bolli R, Tleyjeh IM, et al. Adult bone marrow-derived cells for cardiac repair. Arch Intern Med 2007; 167: 989-97.
18. Cao F, Sun D, Li Ch, et al. Long-term myocardial function improvement after autologous bone marrow mononuclear cells transplantation in patients with ST-segment elevation myocardial infarction: 4 years follow-up. Eur Heart J 2009; 30: 1986-94.
19. Bourdillon PVD, Broderick TM, Sawada SG, et al. Regional wall motion index for infarcted and noninfarcted regions after reperfusion in acute myocardial infarction: comparison with global wall motion index. J Am Soc Echocardiogr 1989; 2: 398-402.