Uncovering genes and regulatory pathways related to urinary albumin excretion

Journal of the American Society of Nephrology

Volumn 22, Issue 1, 2011, Pages 73-81

  Hageman, Rachael S ^a   Leduc, Magalie S ^a   Caputo, Christina R ^a   Tsaih, Shirng Wern ^a   Churchill, Gary A ^a   Korstanje, Ron ^a  

^a JACKSON LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; CREATININE; GLYCAN; RNA;

ANTIGEN PRESENTING CELL; ARTICLE; CELL MIGRATION; CHROMOSOME 1; CHROMOSOME 15; CHROMOSOME 17; CHROMOSOME 4; CONTROLLED STUDY; GENE EXPRESSION; GENETIC REGULATION; GENETIC TRANSCRIPTION; LEUKOCYTE; MALE; MICROARRAY ANALYSIS; MOUSE; MOUSE STRAIN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; QUANTITATIVE TRAIT LOCUS MAPPING; URINARY EXCRETION;

EID: 78651381769     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2010050561     Document Type: Article

References (22)

1. Garrett MR, Pezzolesi MG, Korstanje R: Integrating human and rodent data to identify the genetic factors involved in chronic kidney disease. J Am Soc Nephrol 21: 398-405, 2010
2. Jansen RC, Nap JP: Genetical genomics: The added value from segregation. Trends Genet 17: 388-391, 2001
3. Doorenbos C, Tsaih SW, Sheehan S, Ishimori N, Navis G, Churchill G, Dipetrillo K, Korstanje R: Quantitative trait loci for urinary albumin in crosses between C57BL/6J and A/J inbred mice in the presence and absence of Apoe. Genetics 179: 693-699, 2008
4. Morel L, Rudofsky UH, Longmate JA, Schiffenbauer J, Wakeland EK: Polygenic control of susceptibility to murine systemic lupus erythematosus. Immunity 1: 219-229, 1994
5. Zhang D, Zhang G, Hayden MS, Greenblatt MB, Bussey C, Flavell RA, Ghosh S: A toll-like receptor that prevents infection by uropathogenic bacteria. Science 303: 1522-1526, 2004
6. Smith C, Goldsmith C, Eppig J: The Mammalian Phenotype Ontology as a tool for annotating, analyzing and comparing phenotypic information. Genome Biol 6: R7, 2005
7. Murayama S, Yagyu S, Higo K, Ye C, Mizuno T, Oyabu A, Ito M, Morita H, Maeda K, Serikawa T, Matsuyama M: A genetic locus susceptible to the overt proteinuria in BUF/Mna rat. Mamm Genome 9: 886-888, 1998
8. Rogus JJ, Poznik GD, Pezzolesi MG, Smiles AM, Dunn J, Walker W, Wanic K, Moczulski D, Canani L, Araki S, Makita Y, Warram JH, Krolewski AS: High-density single nucleotide polymorphism genomewide linkage scan for susceptibility genes for diabetic nephropathy in type 1 diabetes: Discordant sibpair approach. Diabetes 57: 2519-2526, 2008
9. Schulz A, Standke D, Kovacevic L, Mostler M, Kossmehl P, Stoll M, Kreutz R: A major gene locus links early onset albuminuria with renal interstitial fibrosis in the MWF rat with polygenetic albuminuria. J Am Soc Nephrol 14: 3081-3089, 2003
10. Grindle S, Garganta C, Sheehan S, Gile J, Lapierre A, Whitmore H, Paigen B, DiPetrillo K: Validation of high-throughput methods for measuring blood urea nitrogen and urinary albumin concentrations in mice. Comp Med 56: 482-486, 2006
11. Cox A, Ackert-Bicknell CL, Dumont BL, Ding Y, Bell JT, Brockmann GA, Wergedal JE, Bult C, Paigen B, Flint J, Tsaih SW, Churchill GA, Broman KW: A new standard genetic map for the laboratory mouse. Genetics 182: 1335-1344, 2009
12. Irizarry RA, Bolstad BM, Collin F, Cope LM, Hobbs B, Speed TP: Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res 31: e15, 2003
13. Lehmann, E: Nonparametrics: Statistical Methods Based on Ranks, San Francisco, Holden-Day, 1975
14. Broman K, Sen S, Owens S, Manichaikul A, Southard-Smith E, Churchill G: The X chromosome in quantitative trait locus mapping. Genetics 174: 2151-2158, 2006 (Pubitemid 46011602)
15. Lander E, Kruglyak L: Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results. Nat Genet 11: 241-247, 1995
16. Broman K, Wu H, Sen S, Churchill G: R/qtl: QTL mapping in experimental crosses. Bioinformatics 19: 889-890, 2003 (Pubitemid 36582406)
17. Storey J: A direct approach to false discovery rates. J R Stat Soc Series B 64: 479-498, 2002
18. Li R, Tsaih SW, Shockley K, Stylianou IM, Wergedal J, Paigen B, Churchill GA: Structural model analysis of multiple quantitative traits. PLoS Genet 2: e114, 2006
19. Chaibub Neto E, Keller MP, Attie AD, Yandell BS: Causal graphical models in systems genetics: A unified framework for joint interference of causal network and genetic architecture for correlated phenotypes. Ann Appl Stat 4: 320-339, 2010
20. Harris MA, Clark J, Ireland A, Lomax J, Ashburner M, Foulger R, Eilbeck K, Lewis S, Marshall B, Mungall C, Richter J, Rubin GM, Blake JA, Bult C, Dolan M, Drabkin H, Eppig JT, Hill DP, Ni L, Ringwald M, Balakrishnan R, Cherry JM, Christie KR, Costanzo MC, Dwight SS, Engel S, Fisk DG, Hirschman JE, Hong EL, Nash RS, Sethuraman A, Theesfeld CL, Botstein D, Dolinski K, Feierbach B, Berardini T, Mundodi S, Rhee SY, Apweiler R, Barrell D, Camon E, Dimmer E, Lee V, Chisholm R, Gaudet P, Kibbe W, Kishore R, Schwarz EM, Sternberg P, Gwinn M, Hannick L, Wortman J, Berriman M, Wood V, de la Cruz N, Tonellato P, Jaiswal P, Seigfried T, White R: The Gene Ontology (GO) database and informatics resource. Nucleic Acids Res 32: D258-D261, 2004
21. Kanehisa M, Goto S: KEGG: Kyoto encyclopedia of genes and genomes. Nucleic Acids Res 28: 27-30, 2000 (Pubitemid 30047706)
22. Falcon S, Gentleman R: Using GOstats to test gene lists for GO term association. Bioinformatics 23: 257-258, 2007 (Pubitemid 46189622)