Development of gut-homing receptors on circulating B cells during infancy

Clinical Immunology

Volumn 138, Issue 1, 2011, Pages 97-106

  Lundell, Anna Carin ^a   Rabe, Hardis ^a   Quiding Järbrink, Marianne ^a   Andersson, Kerstin ^a   Nordström, Inger ^a   Adlerberth, Ingegerd ^a   Wold, Agnes E ^a   Rudin, Anna ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

B cells; Gut homing receptors; Infants

Indexed keywords

ALPHA4BETA7 INTEGRIN; CD27 ANTIGEN; CHEMOKINE RECEPTOR CCR10; CHEMOKINE RECEPTOR CCR9; HOMING RECEPTOR; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; UNCLASSIFIED DRUG;

ARTICLE; B LYMPHOCYTE; CHILD; CONTROLLED STUDY; HUMAN; HUMAN CELL; INFANCY; INFANT; NORMAL HUMAN; PHENOTYPE; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; UMBILICAL CORD BLOOD;

ADULT; ANTIGENS, CD27; B-LYMPHOCYTE SUBSETS; B-LYMPHOCYTES; CHILD, PRESCHOOL; HUMANS; IMMUNE SYSTEM; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; INFANT; INFANT, NEWBORN; INTEGRINS; INTESTINES; LYMPHOCYTE COUNT; MIDDLE AGED; RECEPTORS, CCR; RECEPTORS, CCR10; RECEPTORS, LYMPHOCYTE HOMING;

EID: 78651352717     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2010.10.003     Document Type: Article

References (43)

1. Brandtzaeg P., Halstensen T.S., Kett K., Krajci P., Kvale D., Rognum T.O., Scott H., Sollid L.M. Immunobiology and immunopathology of human gut mucosa: humoral immunity and intraepithelial lymphocytes. Gastroenterology 1989, 97:1562-1584.
2. Conley M.E., Delacroix D.L. Intravascular and mucosal immunoglobulin A: two separate but related systems of immune defense?. Ann. Intern. Med. 1987, 106:892-899.
3. Turnbaugh P.J., Hamady M., Yatsunenko T., Cantarel B.L., Duncan A., Ley R.E., Sogin M.L., Jones W.J., Roe B.A., Affourtit J.P., et al. A core gut microbiome in obese and lean twins. Nature 457 (2009) 480-484.
4. Gill S.R., Pop M., Deboy R.T., Eckburg P.B., Turnbaugh P.J., Samuel B.S., Gordon J.I., Relman D.A., Fraser-Liggett C.M., Nelson K.E. Metagenomic analysis of the human distal gut microbiome. Science 2006, 312:1355-1359.
5. Bos N.A., Jiang H.Q., Cebra J.J. T cell control of the gut IgA response against commensal bacteria. Gut 2001, 48:762-764.
6. Shroff K.E., Meslin K., Cebra J.J. Commensal enteric bacteria engender a self-limiting humoral mucosal immune response while permanently colonizing the gut. Infect. Immun. 1995, 63:3904-3913.
7. Crabbe P.A., Bazin H., Eyssen H., Heremans J.F. The normal microbial flora as a major stimulus for proliferation of plasma cells synthesizing IgA in the gut. The germ-free intestinal tract. Int. Arch. Allergy Appl. Immunol. 1968, 34:362-375.
8. Cebra J.J., Periwal S.B., Lee G., Lee F., Shroff K.E. Development and maintenance of the gut-associated lymphoid tissue (GALT): the roles of enteric bacteria and viruses. Dev. Immunol. 1998, 6:13-18.
9. Farstad I.N., Halstensen T.S., Kvale D., Fausa O., Brandtzaeg P. Topographic distribution of homing receptors on B and T cells in human gut-associated lymphoid tissue: relation of L-selectin and integrin alpha 4 beta 7 to naive and memory phenotypes. Am. J. Pathol. 1997, 150:187-199.
10. Farstad I.N., Halstensen T.S., Lazarovits A.I., Norstein J., Fausa O., Brandtzaeg P. Human intestinal B-cell blasts and plasma cells express the mucosal homing receptor integrin alpha 4 beta 7. Scand. J. Immunol. 1995, 42:662-672.
11. Wagner N., Lohler J., Kunkel E.J., Ley K., Leung E., Krissansen G., Rajewsky K., Muller W. Critical role for beta7 integrins in formation of the gut-associated lymphoid tissue. Nature 1996, 382:366-370.
12. Berg E.L., McEvoy L.M., Berlin C., Bargatze R.F., Butcher E.C. L-selectin-mediated lymphocyte rolling on MAdCAM-1. Nature 1993, 366:695-698.
13. Nakache M., Berg E.L., Streeter P.R., Butcher E.C. The mucosal vascular addressin is a tissue-specific endothelial cell adhesion molecule for circulating lymphocytes. Nature 1989, 337:179-181.
14. Campbell D.J., Butcher E.C. Rapid acquisition of tissue-specific homing phenotypes by CD4(+) T cells activated in cutaneous or mucosal lymphoid tissues. J. Exp. Med. 2002, 195:135-141.
15. Salmi M., Alanen K., Grenman S., Briskin M., Butcher E.C., Jalkanen S. Immune cell trafficking in uterus and early life is dominated by the mucosal addressin MAdCAM-1 in humans. Gastroenterology 2001, 121:853-864.
16. Pabst O., Ohl L., Wendland M., Wurbel M.A., Kremmer E., Malissen B., Forster R. Chemokine receptor CCR9 contributes to the localization of plasma cells to the small intestine. J. Exp. Med. 2004, 199:411-416.
17. Kunkel E.J., Kim C.H., Lazarus N.H., Vierra M.A., Soler D., Bowman E.P., Butcher E.C. CCR10 expression is a common feature of circulating and mucosal epithelial tissue IgA Ab-secreting cells. J. Clin. Invest. 2003, 111:1001-1010.
18. Lazarus N.H., Kunkel E.J., Johnston B., Wilson E., Youngman K.R., Butcher E.C. A common mucosal chemokine (mucosae-associated epithelial chemokine/CCL28) selectively attracts IgA plasmablasts. J. Immunol. 2003, 170:3799-3805.
19. Pan J., Kunkel E.J., Gosslar U., Lazarus N., Langdon P., Broadwell K., Vierra M.A., Genovese M.C., Butcher E.C., Soler D. A novel chemokine ligand for CCR10 and CCR3 expressed by epithelial cells in mucosal tissues. J. Immunol. 2000, 165:2943-2949.
20. Wang W., Soto H., Oldham E.R., Buchanan M.E., Homey B., Catron D., Jenkins N., Copeland N.G., Gilbert D.J., Nguyen N., et al. Identification of a novel chemokine (CCL28), which binds CCR10 (GPR2). J. Biol. Chem. 2000, 275:22313-22323.
21. Hieshima K., Kawasaki Y., Hanamoto H., Nakayama T., Nagakubo D., Kanamaru A., Yoshie O. CC chemokine ligands 25 and 28 play essential roles in intestinal extravasation of IgA antibody-secreting cells. J. Immunol. 2004, 173:3668-3675.
22. Wilson E., Butcher E.C. CCL28 controls immunoglobulin (Ig)A plasma cell accumulation in the lactating mammary gland and IgA antibody transfer to the neonate. J. Exp. Med. 2004, 200:805-809.
23. Homey B., Wang W., Soto H., Buchanan M.E., Wiesenborn A., Catron D., Muller A., McClanahan T.K., Dieu-Nosjean M.C., Orozco R., et al. Cutting edge: the orphan chemokine receptor G protein-coupled receptor-2 (GPR-2, CCR10) binds the skin-associated chemokine CCL27 (CTACK/ALP/ILC). J. Immunol. 2000, 164:3465-3470.
24. Homey B., Alenius H., Muller A., Soto H., Bowman E.P., Yuan W., McEvoy L., Lauerma A.I., Assmann T., Bunemann E., et al. CCL27-CCR10 interactions regulate T cell-mediated skin inflammation. Nat. Med. 2002, 8:157-165.
25. Pakkanen S.H., Kantele J.M., Moldoveanu Z., Hedges S., Hakkinen M., Mestecky J., Kantele A. Expression of homing receptors on IgA1 and IgA2 plasmablasts in blood reflects differential distribution of IgA1 and IgA2 in various body fluids. Clin. Vaccine Immunol. 2010, 17:393-401.
26. Kantele A., Zivny J., Hakkinen M., Elson C.O., Mestecky J. Differential homing commitments of antigen-specific T cells after oral or parenteral immunization in humans. J. Immunol. 1999, 162:5173-5177.
27. Kunkel E.J., Butcher E.C. Plasma-cell homing. Nat. Rev. Immunol. 2003, 3:822-829.
28. Sundstrom P., Lundin S.B., Nilsson L.A., Quiding-Jarbrink M. Human IgA-secreting cells induced by intestinal, but not systemic, immunization respond to CCL25 (TECK) and CCL28 (MEC). Eur. J. Immunol. 2008, 38:3327-3338.
29. Quiding M., Nordstrom I., Kilander A., Andersson G., Hanson L.A., Holmgren J., Czerkinsky C. Intestinal immune responses in humans. Oral cholera vaccination induces strong intestinal antibody responses and interferon-gamma production and evokes local immunological memory. J. Clin. Invest. 1991, 88:143-148.
30. Quiding-Jarbrink M., Nordstrom I., Granstrom G., Kilander A., Jertborn M., Butcher E.C., Lazarovits A.I., Holmgren J., Czerkinsky C. Differential expression of tissue-specific adhesion molecules on human circulating antibody-forming cells after systemic, enteric, and nasal immunizations. A molecular basis for the compartmentalization of effector B cell responses. J. Clin. Invest. 1997, 99:1281-1286.
31. Rott L.S., Briskin M.J., Butcher E.C. Expression of alpha4beta7 and E-selectin ligand by circulating memory B cells: implications for targeted trafficking to mucosal and systemic sites. J. Leukoc. Biol. 2000, 68:807-814.
32. Perfetto S.P., Chattopadhyay P.K., Roederer M. Seventeen-colour flow cytometry: unravelling the immune system. Nat. Rev. Immunol. 2004, 4:648-655.
33. Roederer M. Compensation in flow cytometry. Curr. Protoc. Cytom. 2002, (Dec; Chapter 1:Unit 1 14).
34. Huck K., Feyen O., Ghosh S., Beltz K., Bellert S., Niehues T. Memory B-cells in healthy and antibody-deficient children. Clin Immunol. 2009, 131:50-59.
35. Erle D.J., Briskin M.J., Butcher E.C., Garcia-Pardo A., Lazarovits A.I., Tidswell M. Expression and function of the MAdCAM-1 receptor, integrin alpha 4 beta 7, on human leukocytes. J. Immunol. 1994, 153:517-528.
36. Mebius R.E., Streeter P.R., Michie S., Butcher E.C., Weissman I.L. A developmental switch in lymphocyte homing receptor and endothelial vascular addressin expression regulates lymphocyte homing and permits CD4+ CD3- cells to colonize lymph nodes. Proc. Natl. Acad. Sci. U. S. A. 1996, 93:11019-11024.
37. Klein U., Rajewsky K., Kuppers R. Human immunoglobulin (Ig)M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells. J. Exp. Med. 1998, 188:1679-1689.
38. Agematsu K., Hokibara S., Nagumo H., Komiyama A. CD27: a memory B-cell marker. Immunol. Today 2000, 21:204-206.
39. Fecteau J.F., Cote G., Neron S. A new memory CD27-IgG+ B cell population in peripheral blood expressing VH genes with low frequency of somatic mutation. J. Immunol. 2006, 177:3728-3736.
40. van Gent R., van Tilburg C.M., Nibbelke E.E., Otto S.A., Gaiser J.F., Janssens-Korpela P.L., Sanders E.A., Borghans J.A., Wulffraat N.M., Bierings M.B., et al. Refined characterization and reference values of the pediatric T- and B-cell compartments. Clin. Immunol. 2009, 133:95-107.
41. Dorner T., Radbruch A. Selecting B cells and plasma cells to memory. J. Exp. Med. 201 (2005) 497-499
42. Weller S., Faili A., Garcia C., Braun M.C., Le Deist F.F., de Saint Basile G.G., Hermine O., Fischer A., Reynaud C.A., Weill J.C. CD40-CD40L independent Ig gene hypermutation suggests a second B cell diversification pathway in humans. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:1166-1170.
43. Morrison V.L., Barr T.A., Brown S., Gray D. TLR-mediated loss of CD62L focuses B cell traffic to the spleen during Salmonella typhimurium infection. J. Immunol. 2010, 185:2737-2746.