Metallothionein-2A overexpression increases the expression of matrix metalloproteinase-9 and invasion of breast cancer cells

FEBS Letters

Volumn 585, Issue 2, 2011, Pages 421-428

  Kim, Hyung Gyun ^a   Kim, Jin Young ^a   Han, Eun Hee ^a   Hwang, Yong Pil ^a   Choi, Jae Ho ^a   Park, Bong Hwan ^a   Jeong, Hye Gwang ^a  

^a Chungnam National University   (South Korea)

Author keywords

AP 1; Invasion; Matrix metalloproteinase 9; Metallothionein; NF B

Indexed keywords

GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; METALLOTHIONEIN II; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR AP 1;

ARTICLE; BREAST CANCER; CANCER CELL; CANCER INHIBITION; CANCER INVASION; CELL ACTIVITY; CELL MIGRATION; CELL STRAIN; CELL STRAIN MDA MB 231; CONTROLLED STUDY; ENZYME INDUCTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; TRANSCRIPTION INITIATION;

BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MATRIX METALLOPROTEINASE 9; METALLOTHIONEIN; NEOPLASM INVASIVENESS; NF-KAPPA B; RNA, SMALL INTERFERING; TRANSCRIPTION FACTOR AP-1;

EID: 78651347416     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.12.030     Document Type: Article

References (22)

1. B.H. Bay, R. Jin, J. Huang, and P.H. Tan Metallothionein as a prognostic biomarker in breast cancer Exp. Biol. Med. 231 2006 1516 1521 (Pubitemid 44547844)
2. M. Vasak Advances in metallothionein structure and functions J. Trace Elem. Med. Biol. 19 2005 13 17 (Pubitemid 41253912)
3. K. Inoue, H. Takano, A. Shimada, and M. Satoh Metallothionein as an anti-inflammatory mediator Mediators Inflamm. 2009 2009 101659
4. M.G. Cherian, A. Jayasurya, and B.H. Bay Metallothioneins in human tumors and potential roles in carcinogenesis Mutat. Res. 533 2003 201 209 (Pubitemid 37487869)
5. R. Jin, V.T. Chow, P.H. Tan, S.T. Dheen, W. Duan, and B.H. Bay Metallothionein 2A expression is associated with cell proliferation in breast cancer Carcinogenesis 23 2002 81 86 (Pubitemid 34213555)
6. D. Lim, K.M. Jocelyn, G.W. Yip, and B.H. Bay Silencing the Metallothionein-2A gene inhibits cell cycle progression from G1- to S-phase involving ATM and cdc25A signaling in breast cancer cells Cancer Lett. 276 2009 109 117
7. T.R. Geiger, and D.S. Peeper Metastasis mechanisms Biochim. Biophys. Acta 1796 2009 293 308
8. T. Sreenath, L.M. Matrisian, W. Stetler-Stevenson, S. Gattoni-Celli, and R.O. Pozzatti Expression of matrix metalloproteinase genes in transformed rat cell lines of high and low metastatic potential Cancer Res. 52 1992 4942 4947
9. D.T. Denhardt, A.H. Greenberg, S.E. Egan, R.T. Hamilton, and J.A. Wright Cysteine proteinase cathepsin L expression correlates closely with the metastatic potential of H-ras-transformed murine fibroblasts Oncogene 2 1987 55 59
10. A. Achbarou, S. Kaiser, G. Tremblay, L.G. Ste-Marie, P. Brodt, D. Goltzman, and S.A. Rabbani Urokinase overproduction results in increased skeletal metastasis by prostate cancer cells in vivo Cancer Res. 54 1994 2372 2377 (Pubitemid 24138727)
11. J.P. Sluijter, D.P. de Kleijn, and G. Pasterkamp Vascular remodeling and protease inhibition-bench to bedside Cardiovasc. Res. 69 2006 595 603 (Pubitemid 43139723)
12. E.I. Deryugina, and J.P. Quigley Matrix metalloproteinases and tumor metastasis Cancer Metastasis Rev. 25 2006 9 34
13. A. Kohrmann, U. Kammerer, M. Kapp, J. Dietl, and J. Anacker Expression of matrix metalloproteinases (MMPs) in primary human breast cancer and breast cancer cell lines: new findings and review of the literature BMC Cancer 9 2009 188
14. R. Roy, J. Yang, and M.A. Moses Matrix metalloproteinases as novel biomarkers and potential therapeutic targets in human cancer J. Clin. Oncol. 27 2009 5287 5297
15. J. Walter-Yohrling, X. Cao, M. Callahan, W. Weber, S. Morgenbesser, S.L. Madden, C. Wang, and B.A. Teicher Identification of genes expressed in malignant cells that promote invasion Cancer Res. 63 2003 8939 8947 (Pubitemid 38064074)
16. I. Kazes, I. Elalamy, J.D. Sraer, M. Hatmi, and G. Nguyen Platelet release of trimolecular complex components MT1-MMP/TIMP2/MMP2: involvement in MMP2 activation and platelet aggregation Blood 96 2000 3064 3069
17. W. Eberhardt, M. Schulze, C. Engels, E. Klasmeier, and J. Pfeilschifter Glucocorticoid-mediated suppression of cytokine-induced matrix metalloproteinase-9 expression in rat mesangial cells: involvement of nuclear factor-kappaB and Ets transcription factors Mol. Endocrinol. 16 2002 1752 1766 (Pubitemid 34828086)
18. H.J. Cho, J.H. Kang, J.Y. Kwak, T.S. Lee, I.S. Lee, N.G. Park, H. Nakajima, J. Magae, and Y.C. Chang Ascofuranone suppresses PMA-mediated matrix metalloproteinase-9 gene activation through the Ras/Raf/MEK/ERK- and Ap1-dependent mechanisms Carcinogenesis 28 2007 1104 1110 (Pubitemid 47072197)
19. X. Yap, H.Y. Tan, J. Huang, Y. Lai, G.W. Yip, P.H. Tan, and B.H. Bay Over-expression of metallothionein predicts chemoresistance in breast cancer J. Pathol. 217 2009 563 570
20. S. Zbinden, J. Wang, R. Adenika, M. Schmidt, J.U. Tilan, A.H. Najafi, X. Peng, R.M. Lassance-Soares, M. Iantorno, H. Morsli, L. Gercenshtein, G.J. Jang, S.E. Epstein, and M.S. Burnett Metallothionein enhances angiogenesis and arteriogenesis by modulating smooth muscle cell and macrophage function Arterioscler. Thromb. Vasc. Biol. 30 2010 477 4782
21. Y.P. Hwang, H.J. Yun, H.G. Kim, E.H. Han, G.W. Lee, and H.G. Jeong Suppression of PMA-induced tumor cell invasion by dihydroartemisinin via inhibition of PKCalpha/Raf/MAPKs and NF-kappaB/AP-1-dependent mechanisms Biochem. Pharmacol. 79 2010 1714 1726
22. M.H. Pan, Y.S. Chiou, W.J. Chen, J.M. Wang, V. Badmaev, and C.T. Ho Pterostilbene inhibited tumor invasion via suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells Carcinogenesis 30 2009 1234 1242