Anticonvulsant activity of embelin isolated from Embelia ribes

Phytomedicine

Volumn 18, Issue 2-3, 2011, Pages 186-188

  Mahendran, S ^a   Thippeswamy, B S ^b   Veerapur, V P ^b   Badami, S ^b  

^a JSS COLLEGE OF PHARMACY   (India)

^b SREE SIDDAGANGA COLLEGE OF PHARMACY   (India)

Author keywords

Embelia ribes; Embelin; GABAA receptor; Maximal electroshock; Seizures

Indexed keywords

DIAZEPAM; EMBELIN; PENTETRAZOLE; PHENYTOIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CENTRAL NERVOUS SYSTEM DEPRESSION; CONTROLLED STUDY; DOSE RESPONSE; DRUG ISOLATION; DRUG STRUCTURE; ELECTRIC SHOCK; EMBELIA RIBES; LOCOMOTION; MEDICINAL PLANT; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SEIZURE; TONIC CLONIC SEIZURE;

ANIMALS; ANTICONVULSANTS; BENZOQUINONES; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DIAZEPAM; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROSHOCK; EMBELIA; LOCOMOTION; PENTYLENETETRAZOLE; PHENYTOIN; PHYTOTHERAPY; PLANT EXTRACTS; RATS; SEIZURES;

EMBELIA RIBES;

EID: 78651317905     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2010.04.002     Document Type: Article

References (17)

1. C.K. Atal, M.A. Siddiqui, Z. Usha, V. Amla, R.K. Johri, and P.G. Rao Non-narcotic orally effective, centrally acting analgesic from an ayurvedic drug J. Ethnopharmacol. 11 1984 309 317
2. M. Chitra, C.S.S. Devi, and E. Sukumar Antibacterial activity of embelin Fitoterapia 74 2003 401 403
3. M. Chitra, C.S. Shyamala devi, S. Viswanathan, and E. Sukumar Effect of embelin on lipid profile in transplanted fibrosarcoma in rats Indian J. Pharmacol. 35 2003 241 244
4. S. Dharmendra, S. Ruchi, S. Pahup, and R.S. Gupta Effect of embelin on lipid peroxidation and free radical scavanging activity against liver damage in rats Basic Clin. Pharmacol. Toxicol. 105 2009 243 248
5. G.E. Feresin, A. Tapia, M. Sortino, S. Zacchino, A.R. Arias, and A. Inchausti Bioactive alkyl phenols and embelin from Oxalis erythrorhiza J. Ethnopharmacol. 88 2003 241 247
6. K. Gale GABA and epilepsy: basic concepts from preclinical research Epilepsia 33 1992 S3 S12
7. H. Hosseinzadeh, and S. Parvardeh Anticonvulsant effects of thymoquinone, the major constituent of Nigella sativa seeds in mice Phytomedicine 11 2004 56 64
8. V.K. Kapoor, A.S. Chawla, M. Kumar, and P. Kumar Anti-inflammatory agent in Indian Laboratories Indian Drugs 30 1983 481 488
9. S.K. Kulkarni Hand Book of Experimental Pharmacology 1999 Vallabh Prakashan New Delhi, India pp. 117-119
10. H.M. Kumara Swamy, V. Krishna, K. Shankarmurthy, B. Abdul Rahiman, K.L. Mankani, and K.M. Mahadevan Wound healing activity of embelin isolated from the ethanol extract of leaves of Embelia ribes Burm. J. Ethnopharmacol. 109 2007 529 534
11. K. Poole, N. Moran, G. Bell, J. Solomon, S. Kendall, M. McCarthy, D. McCormick, L. Nashef, A. Jhonson, J. Sander, and S. Shorvon Patient's perspectives on services for epilepcy: a survey of patient satisfaction, preferences and information provision in 2394 people with epilepsy Seizure 9 2000 551 558
12. H.M. Salahdeen, and O.K. Yemitan Neuropharmacological effects of aqueous leaf extract of Bryophyllum pinnatum in mice Afr. J. Biol. Med. Res. 9 2006 101 107
13. P. Sokoloff, B. Giros, M.P. Martres, M.L. Bouthenet, and J.C. Schwartz Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics Nature 347 1990 146 151
14. E.A. Swinyard, and H.J. Kupferberg Antiepileptic drugs: detection, quantification, and evaluation Fed. Proc. 44 1985 39 43
15. V.D. Thakur, and S.A. Mengi Neuropharmacological profile of Eclipta alba L. Hassk. J. Ethnopharmacol. 102 2005 23 31
16. P.S. Varier Indian Medicinal Plants, a Compendium of 500 Species vol. 2 2006 Orient Longman (Pvt) Ltd. Chennai, India pp. 368-371
17. J.A. Vida Anticonvulsants Principles of Medicinal Chemistry 1995 Williams and Wilkins London pp. 182-198