The genus Artemisia: A comprehensive review

Pharmaceutical Biology

Volumn 49, Issue 1, 2011, Pages 101-109

  Bora, Kundan Singh ^a   Sharma, Anupam ^b  

^a LR Institute of Pharmacy   (India)

^b PANJAB UNIVERSITY   (India)

Author keywords

Antimalarial; Antimicrobial; Artemisia; Cytotoxic; Flavonoids; Terpenoids.

Indexed keywords

ACETYLENE; ARTEMISIA ABROTANUM EXTRACT; ARTEMISIA ABSINTHIUM EXTRACT; ARTEMISIA AFRA EXTRACT; ARTEMISIA ANNUA EXTRACT; ARTEMISIA ARBORESCENS EXTRACT; ARTEMISIA ASIATICA EXTRACT; ARTEMISIA CAMPESTRIS EXTRACT; ARTEMISIA CAPILLARIS EXTRACT; ARTEMISIA DOUGLASIANA EXTRACT; ARTEMISIA DRACUNCULUS EXTRACT; ARTEMISIA EXTRACT; ARTEMISIA JUDAICA EXTRACT; ARTEMISIA MARITIMA EXTRACT; ARTEMISIA MOGOLTAVICA EXTRACT; ARTEMISIA MONOSPERMAL EXTRACT; ARTEMISIA NILAGIRICA EXTRACT; ARTEMISIA SCOPARIA EXTRACT; ARTEMISIA TRIPARTITE EXTRACT; ARTEMISIA VERLOTORUM EXTRACT; ARTEMISIA VESTITA EXTRACT; ARTEMISIA VULGARIS EXTRACT; ARTEMISININ; CHLOROGENIC ACID; COUMARIN; ESSENTIAL OIL; FLAVONOID; HERBACEOUS AGENT; TERPENOID; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTEMISIA; ARTEMISIA ABROTANUM; ARTEMISIA ABSINTHIUM; ARTEMISIA AFRA; ARTEMISIA ANNUA; ARTEMISIA ARBORESCENS; ARTEMISIA ASIATICA; ARTEMISIA CAMPESTRIS; ARTEMISIA CAPILLARIS; ARTEMISIA DOUGLASIANA; ARTEMISIA JUDAICA; ARTEMISIA MARITIMA; ARTEMISIA MOGOLTAVICA; ARTEMISIA MONOSPERMAL; ARTEMISIA NILAGIRICA; ARTEMISIA SCOPARIA; ARTEMISIA TRIPARTITE; ARTEMISIA VESTITA; ARTEMISIA VULGARIS; BIOLOGICAL ACTIVITY; CHINESE MEDICINE; DRUG DETERMINATION; DRUG MECHANISM; DRUG STRUCTURE; LIVER PROTECTION; LIVER TOXICITY; NONHUMAN; PHYTOCHEMISTRY; REVIEW; SYSTEMATIC REVIEW; TRADITIONAL MEDICINE;

ANIMALS; ARTEMISIA; DRUG DISCOVERY; ETHNOPHARMACOLOGY; HUMANS; PHYTOTHERAPY; PLANT EXTRACTS;

ARTEMISIA; ARTEMISIA ANNUA;

EID: 78651274406     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880209.2010.497815     Document Type: Review

References (124)

1. Abdelgaleil-Samir AM, Abbassy Moustafa A, Belal Abdel-Salam H, Abdel Rasoul MA. (2008). Bioactivity of two major constituents isolated from the essential oil of Artemisia judaica. Bioresource Technol, 99, 5947-5950.
2. Abdul RA, Waheeta H. (2010). Antibacterial activity of Artemisia nilagirica leaf extracts against clinical and phytopathogenic bacteria. BMC CAM, 10, 1-20.
3. Adams JD, Garcia C. (2006). Women′s health among the Chumash. eCAM, 1-7.
4. Ali MS, Jahangir M, Saleem M. (2003). Structural distinction between sabandins A and B from Artemisia scoparia Waldst. Nat Prod Res 17, 1-4.
5. Aniya Y, Shimabukuro M, Shimoji M, Kohatsu C, Kunii D, Takayama F, Egashira T. (2000). Antioxidant and hepatoprotective actions of the medicinal herb Artemisia campestris from the Okinawa Islands. Biol Pharm Bull, 23, 309-312.
6. Bayrak A, Dogan A, Akgul A. (1986). Research on essential oil components from tarragon (Artemisia dracunculus). Turk Tarimve Ormancilik Dergisi, 10, 314-318.
7. Benli M, Kaya I, Yigit N. (2007). Screening antimicrobial activity of various extracts of Artemisia dracunculus. Cell Biochem Funct, 25, 681-686.
8. Bergendorf O, Sterner O. (1995). Spasmolytic favonols from Artemisia abrotanum. Planta Med, 61, 370-371.
9. Bhagwati U. (2003.) Utilization of medicinal plants by the rural women of Kulu, Himachal Pradesh. Indian J Tradi Knowl, 2, 366-370.
10. Bhakuni DS, Goel AK, Jain S, Mehrotra BN, Srimal RC. (1990). Screening of Indian plants for biological activity, part XIV. Indian J Exp Biol, 28, 619-637.
11. Boareto AC, Muller JC, Bufalo AC, Botelho GGK, de Araujo SL, Foglio MA, de Morais RN, Dalsenter PR. (2008). Toxicity of artemisinin (Artemisia annua L.) in two diferent periods of pregnancy in Wistar rats. Reprod Toxicol, 25, 239-246.
12. Borsutzki LH. (1955). Chemistry of Artemisia maritima. Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, 288, 336-340.
13. Calderone V, Martinotti E, Baragatti B, Breschi MC, Morelli I. (1999). Vascular effects of aqueous crude extracts of Artemisia verlotorum, in vivo and in vitro pharmacological studies in rats. Phytother Res, 13, 645-648.
14. Carnat A, Heitz A, Fraisse A, Carnat AP, Lamaison JL. (2000). Major dicafeoylquinic acids from Artemisia vulgaris. Fitoterapia, 71, 587-589.
15. Cavaleiro JAS. (1986). Iso-sakuranetin, a favonone from Artemisia campestris sub-sp. maritima. Fitoterapia, 57, 278-279.
16. Cha JD, Jeong MR, Jeong SI, Moon SE, Kim JY, Kil BS, Song YH. (2005). Chemical composition and antimicrobial activity of the essential oils of Artemisia scoparia and Artemisia capillaries. Planta Med, 71, 186-190.
17. Chan K. (2003). Some aspects of toxic contaminants in herbal medicines. J Chemosphere, 52, 1361-1371.
18. Chandrasekharan I, Khan HA, Ghanim A. (1981). Flavonoids from Artemisia scoparia. Planta Med, 43, 310-311.
19. Chemesova II, Belenovskaya LM, Stukov AN. (1987). Antitumor activity of favonoids from some species of Artemisia L. Rastitel′nye Resursy, 23, 100-103.
20. Chopra RN, Roy DN, Ghosh SM. 1940. Blumea densifora and Artemisia vulgaris: Teir insecticidal and larvicidal properties. J Malaria Inst India, 3, 495, 1066.
21. Covello M. (1941). Composition of the essential oil of Artemisia verlotorum Lamotte. Napoli, 15, 61-71.
22. Daise LL, Daniela SA, Celuta SA, Paul PK. (2008). Screening of chemical composition, antimicrobial and antioxidant activities of Artemisia essential oils. Phytochemistry, 69, 1732-1738.
23. Fahmy IR, Ahmed ZF, Maher A, Moneim FA. (1968). Te insecticidal properties of the essential oil of Artemisia monospermal. Bulletin de l′Institut du Desert d′Egypte, 8, 49-59.
24. Ferrolino-Calumpang SM, Padolina WG. (1985). Insecticidal activity screening and isolation of the major crystalline fraction of Artemisia vulgaris L. Philippine Agriculturist, 68, 249-261.
25. Foglio MA, Dias PC, Antonio MA, Possenti A, Rodrigues RAF, da Silva E F, Rehder VL, de Carvalho JE. (2002). Antiulcerogenic activity of some sesquiterpene lactones isolated from Artemisia annua. Planta Med, 68, 515-518.
26. Garcia C, Adams J. (2005). Healing with Medicinal Plants of the West-Cultural and Scientifc Basis for their Use. La Crescenta, CA: Abedus Press.
27. Gilani AH, Yaeesh S, Jamal Q, Ghayur MN. (2005). Hepatoprotective activity of aqueous-methanol extract of Artemisia vulgaris. Phytother Res, 19, 170-172.
28. Goryaev MI, Shabanov IM. (1953). Essential oil of Artemisia mogoltavica. Ser Khim, 7, 75-78.
29. Govindaraj S, Kumari BDR, Cioni PL, Flamini G. (2008). Mass propagation and essential oil analysis of Artemisia vulgaris. J Biosci Bioeng, 105, 176-183.
30. Govorko D, Logendra S, Wang Y, Komarnytsky S, Cefalu WT, Raskin I. (2007). Polyphenolic compounds from Artemisia dracunculus L. inhibit PEPCK gene expression and gluconeogenesis in an H4IIE hepatoma cell line. Am J Physiol, 293, E1503-1510.
31. Greger H, Hofer O. (1980). New unsymmetrical substituted tetrahydrofurofuran lignans from Artemisia absinthium. Assignment of the relative stereochemistry by lanthanide induced chemical shift. Tetrahedron, 36, 3551-3558.
32. Guarrera PM. (2005). Traditional phytotherapy in central Italy (Marche, Abruzzo, and Latium). Fitoterapia, 76, 1-25.
33. Guven KC. (1963). Turkish Artemisia species. II. Artemisia campestris. Folia Pharm, 5, 586-591.
34. Hammoda HM, Ela MA, El-Lakany AM, El-Hanbali O, Zaki CS, Ghazy NM. (2008). New constituents of Artemisia monosperma. Del Die Pharmazie, 63, 611-614.
35. Han J, Ye M, Qiao X, Xu M, Wang BR, Guo DA. (2008). Characterization of phenolic compounds in the Chinese herbal drug Artemisia annua by liquid chromatography coupled to electrospray ionization mass spectrometry. J Pharmaceut Biomed, 47, 516-525.
36. Han KH, Jeon YJ, Athukorala Y, Choi KD, Kim CJ, Cho JK, Sekikawa M, Fukushima M, Lee CH. (2006). A water extract of Artemisia capillaris prevents 2,2′-azobis(2-amidinopropane) dihydrochloride-induced liver damage in rats. J Med Food, 9, 342-347.
37. Han X, Ma X, Zhang T, Zhang Y, Liu Q, Ito Y. (2007). Isolation of high-purity casticin from Artemisia annua by high-speed counter-current chromatography. J Chromatogr, 1151, 180-182.
38. Harsha VH, Hebbar SS, Hegde GR, Shripatti V. (2002). Ethnomedical knowledge of plants used by Kunabi tribe of Karnataka in India. Fitoterapia, 73, 281-287.
39. Heo HJ, Yang HC, Cho HY, Hong B, Lim ST, Park HJ, Kim KH, Kim HK, Shin DH. (2000). Inhibitory effect of Artemisia asiatica alkaloids on acetylcholinesterase activity from rat PC12 cells. Mol Cell, 10, 253-262.
40. Heywood VH, Humphries CJ. (1997). Anthemideae systematic review. In: Heywood VH, ed. Te Biology and Chemistry of the Compositae. London: Academic Press, 868.
41. Hofer O, Szabo G, Greger H. (1986). 2-Hydroxy-4-methoxy-trans-cinnamic acid as a precursor of herniarin in Artemisia dracunculus. Monatshefte Fuer Chemie, 117, 1219-1222.
42. Hong JH, Lee IS. (2009). Efects of Artemisia capillaris ethyl acetate fraction on oxidative stress and antioxidant enzyme in high-fat diet induced obese mice. Chemico-Biol Interact, 179, 88-93.
43. Hong JH, Lee JW, Park JH, Lee IS. (2007). Antioxidative and cytoprotective effects of Artemisia capillaris fractions. Biofactors, 31, 43-53.
44. Irwin MA, Geissman TA. (1969). Sesquiterpene lactones. Constituents of Artemisia nova and A. tripartita subspecies rupicola. Phytochemistry, 8, 305-311.
45. Ishibashi K, Katsuhara J, Hashimoto K, Kobayashi M. (1965). Terpenes and terpenoids in the neutral fraction of the essential oil of Artemisia maritima. Kogyo Kagaku Zasshi, 68, 1224-1228.
46. Jaitak V, Singh B, Kaul VK. (2008). Variability of volatile constituents in Artemisia maritima in western Himalaya. Nat Prod Res, 22, 565-568.
47. Jakupovic J, Tan RX, Bohlmann F, Jia ZJ, Huneck S. (1991). Acetylenes and other constituents from Artemisia dracunculus. Planta Med, 57, 450-453.
48. Janbaz KH, Gilani AH. (1995). Evaluation of the protective potential of Artemisia maritima extract on acetaminophen-and CCl4-induced liver damage. Pakistan J Ethnopharmacol, 47, 43-47.
49. Janot MM, Mouton R. (1930). Te toxicity of the seeds from Artemisia maritima L. compared with that of santonin. Pharmacologiques, 37, 593-599.
50. Jasna M, Canadanovic B, Sonja MD, Gordana SC, Vesna TT. (2004). Free-radical scavenging activity of wormwood (Artemisia absinthium) extracts. J Sci Food Agr, 85, 265-272.
51. Jin H, Yan-Ling Z, Li-Mei S, Feng-Jiao H, Xiao-He X. (2005). An experiment on standardized cell culture assay in assessing the activities of Composite Artemisia capillaries Tablets against hepatitis B virus replication in vitro. Chinese J Integr Med, 1, 54-56.
52. Juteau F, Jerkovic I, Masotti V, Milos M, Mastelic J, Bessiere JM, Viano J. (2003). Composition and antimicrobial activity of the essential oil of Artemisia absinthium from Croatia and France. Planta Med, 69, 158-161.
53. Kaczmarek F, Malek B. (1955). Santonin extracted from indigenous Artemisia maritima. Acta Pol Pharm, 12, 173-177.
54. Kalemba D, Kusewicz D, Swiader K. (2002). Antimicrobial properties of the essential oil of Artemisia asiatica Nakai. Phytother Res, 16, 288-291.
55. Kim EK, Kwon KB, Han MJ, Song MY, Lee JH, Lv N, Choi KB, Ryu DG, Kim KS, Park JW, Park BH. (2007). Inhibitory effect of Artemisia capillaris extract on cytokine-induced nitric oxide formation and cytotoxicity of RINm5F cells. Int J Mole Med, 19, 535-540.
56. Kim YS, Bahn KN, Hah CK, Gang HI, Ha YL. (2008). Inhibition of 7,12-dimethylbenz[a]anthracene induced mouse skin carcinogenesis by Artemisia capillaries. J Food Sci, 73, T16-20.
57. Kiso Y, Ogasawara S, Hirota K, Watanabe N, Oshima Y, Konno C, Hikino H. (1984). Antihepatotoxic principles of Artemisia capillaries buds. Planta Med, 50, 81-85.
58. Kolodziejski J, Stanislaw G, Surewicz H. (1959). Chemical composition of Artemisia abrotanum. Dissertationes Pharmaceuticae, 11, 67-74.
59. Kordali S, Cakir A, Mavi A, Kilic H, Yildirim A. (2005). Screening of chemical composition and antifungal and antioxidant activities of the essential oils from three Turkish Artemisia species. J Agr Food Chem, 53, 1408-1416.
60. Kotnis MS, Patel P, Menon SN, Sane RT. (2004). Reneprotective effect of Hemisdesmus indicus, a herbal drug used in gentomicin-induced renal toxicity. Nephrology, 3, 142-152.
61. Kranen-Fiedler U. (1956). Some ingredients of Artemisia abrotanum. Arzneimittel-Forsch, 6, 475-479.
62. Kundan SB, Anupam S. (2010). Neuroprotective effect of Artemisia absinthium L. on focal ischemia and reperfusion-induced cerebral injury. J Ethnopharmacol, 129, 1-7.
63. Leung AY. (1980). Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics. New York: Wiley.
64. Lim BO, Chung HG, Lee WH, Lee HW, Suk K. (2008). Inhibition of microglial neurotoxicity by ethanol extract of Artemisia asiatica Nakai. Phytother Res, 22, 279-282.
65. Lin S, Yong-Qing X, Qi-Wei Z, Ning-Ning Z. (2004). Studies on chemical constituents in bud of Artemisia scoparia (II). Zhongguo Zhongyao Zazhi, 29, 152-154.
66. Liu CZ, Murch SJ, El-Demerdash M, Saxena PK. (2004). Artemisia judaica L., micropropagation and antioxidant activity. J Biotechnol, 110, 63-71.
67. Liu NQ, Van der Kooy F, Verpoorte R. (2009). Artemisia afra, A potential fagship for African medicinal plants? S Afr J Bot, 75, 185-195.
68. Macchioni F, Perrucci S, Flamini G, Cioni PL, Morelli I. (1999). Antimycotic activity against Saprolegnia ferax of extracts of Artemisia verlotorum and Santolina etrusca. Phytother Res, 13, 242-244.
69. Maksudov NK, Pogorelko IP, Yuldashev PKA. (2003). Chemical investigation of Artemisia scoparia. Usbeksk Khim Zh (1962), 6, 84-86.
70. Mashimo K, Shimizu K, Chihara G. (1963). Cholagogues. Te cholagogic action of Artemisia capillaries. Saishin Igaku, 18, 1430-1434.
71. Mazur Y, Meisels A. (1955). Te isolation of 5-hydroxy-3,6,7,3′, 4′-pentamethoxyfavone from Artemisia arborescens. B Res Coun Israel, 5A, 67-69.
72. Mehrdad I, Seyed EA, Meysam MS. (2007). Detection of sesquiterpene lactones in ten Artemisia species population of Khorasan provinces. Iran J Basic Medi Sci, 10, 183-188.
73. Min-Jung K, Do-Hee K, Hye-Kyung N, Tae-Young O, Chang-Yell S, Young-Joon S. (2005). Eupatilin, a pharmacologically active favone derived from Artemisia plants, induces apoptosis in human gastric cancer cells. J Environ Pathol Tox, 24, 261-269.
74. Moerman D. (1998). Native American Ethnobotany. Portland: Timber Press.
75. Mucciarelli M, Mafel M. (2002). Introduction to the Genus. In: Wright, C.W., ed. Artemisia. Medicinal and Aromatic Plants-Industrial Profles, Vol. 18. London: Taylor and Francis, 1-50.
76. Mueller MS, Karhagomba IB, Hirt HM, Wemakor E. (2000). Te potential of Artemisia annua as a locally produced remedy for malaria in the tropics, agricultural, chemical and clinical aspects. J Ethnopharmacol, 73, 487-493.
77. Murray RDH, Stefanovic M. (1986). 6-Methoxy-7,8-methylenedioxycoumarin from Artemisia dracunculoides and Artemisia vulgaris. J Nat Prod, 49, 550-551.
78. Muyima NYO, Zulu G, Bhengu T, Popplewell D. (2002). Te potential application of some novel essential oils as natural cosmetic preservatives in an aqueous cream formulation. Flavour Frag J, 17, 258-266.
79. Negahban M, Moharramipour S, Sefdkon F. (2006). Chemical composition and insecticidal activity of Artemisia scoparia essential oil against three coleopteran stored-product insects. J Asia-Pac Entomol, 9, 381-388.
80. Oswiecimska M, Polak A, Seidl O, Sendra J. (1965). Comparative study of chromatograms of the favonoid fractions from herbs of some species of the genus Artemisia. Dissertationes Pharmaceuticae, 17, 503-511.
81. Parihar DB, Dutt S. (1950). Chemical examination of the fxed oil of Artemisia scoparia. Indian Soap J, 15, 161-165.
82. Park EJ, Nan JX, Kim JY, Kang HC, Choi JH, Lee SJ, Kim YC, Sohn DH. (2000). Te ethanol-soluble part of a hot-water extract from Artemisia iwayomogi inhibits liver fbrosis induced by carbon tetrachloride in rats. J Pharmacy Pharmacol, 52, 875-881.
83. He SP, Tan GY, Li G, Tan WM, Nan TG, Wang BM, Li ZH, Li QX. (2009). Development of a sensitive monoclonal antibody-based enzyme-linked immunosorbent assay for the antimalaria active ingredient artemisinin in the Chinese herb Artemisia annua. Anal Bioanal Chem, 393, 1297-1303.
84. Pires JM, Mendes FR, Negri G, Duarte-Almeida JM, Carlini EA. (2009). Antinociceptive peripheral effect of Achillea millefolium L. and Artemisia vulgaris L., both plants known popularly by brand names of analgesic drugs. Phytother Res, 23, 212-119.
85. Polyakov P, Shishkin BK. (1995). Artemisia in Flora of the USSR. Koeringstein Germany: Bisnen Singh Scientifc Books, 488-489.
86. Qi-Wei Z, Yong-Xi Z, Ying Z, Yong-Qing X, Zhi-Min W. (2002). Studies on chemical constituents in buds of Artemisia scoparia. Zhongguo Zhongyao Zazhi, 27, 202-204.
87. Ragasa CY, de Jesus JP, Apuada MJ, Rideout JA. (2008). A new sesquiterpene from Artemisia vulgaris. Nature Med, 62, 461-463.
88. Rattu A, Maccioni A. (1953). Essential oils of Sardinian aromatic plants. I V. Essence from Artemisia arborescens. Rend Seminar Fac Sci Univ Cagliari, 23, 91-96.
89. Reddy AM, Lee JY, Seo JH, Kim BH, Chung EY, Ryu SY, Kim YS, Lee CK, Min KR, Kim Y. (2006). Artemisolide from Artemisia asiatica, nuclear factor-kappaB inhibitor suppressing prostaglandin E2 and nitric oxide production in macrophages. Archiv Pharmacol Res, 29, 591-597.
90. Remberg P, Bjork L, Hedner T, Sterner O. (2004). Characteristics, clinical effect profle and tolerability of a nasal spray preparation of Artemisia abrotanum for allergic rhinitis. Int J Phytother Phytopharmacol, 11, 36-42.
91. Ribnicky DM, Poulev A, Watford M, Cefalu W T, Raskin I. (2006). Antihyperglycemic activity of Tarralin TM, an ethanol extract of Artemisia dracunculus. Phytomedicine, 13, 550-557.
92. Ryu BK, Ahn BO, Oh TY, Kim SH, Kim WB, Lee EB. (1998). Studies on protective effect of DA-9601), Artemisia asiatica extract, on acetaminophen-and CCl4-induced liver damage in rats. Arch Pharmacol Res, 21, 508-513.
93. Saber AH, Khafagy SM. (1958a). Te study of Artemisia judaica. Egypt Pharm Bull, 40, 91-95.
94. Saber AH, Khafagy SM. (1958b). Artemisia judaica. Egypt Pharm Bull, 40, 37-43.
95. Saddi M, Sanna A, Cottiglia F, Chisu L, Bonsignore L, De Logu A. (2007). Antiherpevirus activity of Artemisia arborescens essential oil and inhibition of lateral difusion in Vero cells. Ann Clin Microbiol Antimicrob, 6, 10.
96. Saratikov AS, Prishchep TP, Vengerovskii AI, Taran DD, Beresovskaya TP, Kalinkina G, Serykh EA. (1986). Anti-infammatory properties of essential oils of Achillea asiatica and some species of Artemisia. Khimiko-Farmatsevticheskii Zhurnal, 20, 585-588.
97. Shahriyary L, Yazdanparast R. (2007). Inhibition of blood platelet adhesion, aggregation and secretion by Artemisia dracunculus leaves extracts. J Ethnopharmacol, 114, 194-198.
98. Sharaf A, Fahmy IR, Ahmed ZF, Moneim FA. (1959). Pharmacological study of Artemisia monospermal. Egypt Pharml Bull, 41, 47-52.
99. Singh HP, Kaur S, Mittal S, Batish DR, Kohli RK. (2008). Phytotoxicity of major constituents of the volatile oil from leaves of Artemisia scoparia Waldst. & Kit. J Biosci, 63, 663-666.
100. Singh HP, Kaur S, Mittal S, Batish DR, Kohli RK. (2009). Essential oil of Artemisia scoparia inhibits plant growth by generating reactive oxygen species and causing oxidative damage. J Chem Ecol, 35, 154-162.
101. Sinitsyn GS, Sinitsyn GS. (1960). Dynamics of accumulation of santonins in cultivated Artemisia. Izvest Akad Nauk Kazakh SSR, 3, 86-93.
102. Slepetys J. (1975). Biology and biochemistry of wormwood. Accumulation dynamics of tannins, ascorbic acid, and carotene. Liet TSR Mokslu Akad Darb Ser C, 1, 43-148.
103. Stavri M, Ford CHJ, Bucar F, Streit B, Hall ML, Williamson RT, Mathew KT, Gibbons S. (2005). Bioactive constituents of Artemisia monospermal. Phytochemistry, 66, 233-239.
104. Swanston-Flatt SK, Flatt PR, Day C, Bailey CJ. (1991). Traditional dietary adjuncts for the treatment of diabetes mellitus. Proc Nutr Soc, 50, 641-651.
105. Tan RX, Lu H, Wolfender JL, Yu TT, Zheng WF, Yang L, Gafner S, Hostettmann K. (1999). Mono-and sesquiterpenes and antifungal constituents from Artemisia species. Planta Med, 65, 64-67.
106. Tan RX, Tang HQ, Hu J, Shuai B. (1998). Lignans and sesquiterpene lactones from Artemisia sieversiana and Inula racemosa. Phytochemistry, 49, 157-161.
107. Tanaka K. (1961). Antimicrobial activity of capillin, a component of the essential oil of Artemisia capillaris and of its derivatives. Seikagaku, 33, 399-409.
108. Tariq KA, Chishti MZ, Ahmad F, Shawl AS. (2009). Anthelmintic activity of extracts of Artemisia absinthium against ovine nematodes. Vet Parasitol, 160, 83-88.
109. Temraz A, El-Tantawy WH. (2008). Characterization of antioxidant activity of extract from Artemisia vulgaris. Pakistan J Pharm Sci, 21, 321-326.
110. Tring TSA, Weitz FM. (2006). Medicinal plant use in the Bredasdorp/Elim region of the Southern Overberg in the Western Cape Province of South Africa. J Ethnopharmacol, 103, 261-275.
111. Tigno XT, de Guzman F, Flora AM. (2000). Phytochemical analysis and hemodynamic actions of Artemisia vulgaris L. Clin Hemorheol Micro, 23, 167-175.
112. Trumpowskaand M, Olszewski Z. (1968). Chromatographic analysis of the essential oil from Artemisia vulgaris harvested in various seasons. Acta Pol Pharm, 25, 319-328.
113. Tunon H, Torsell W, Mikiver A, Malander I. (2006). Arthropod repellency, especially tick (Ixodes ricinus), exerted by extract from Artemisia abrotanum and essential oil from fowers of Dianthus caryophyllum. Fitoterapia, 77, 257-261.
114. Wake G, Court J, Pickering A, Lewis R, Wilkins R, Perry E. (2000). CNS acetylcholine receptor activity in European medicinal plants traditionally used to improve failing memory. J Ethnopharmacol, 69, 105-114.
115. Watson LE, Bates PL, Evans TM, Unwin MM, Estes JR. (2002). Molecular phylogeny of Subtribe Artemisiinae (Asteraceae), including Artemisia and its allied and segregate genera. BMC Evol Biol, 2, 17.
116. Wei ZX, Pan JP, Li Y. (1992). Artemisinin G, a sesquiterpene from Artemisia annua. Planta Med, 58, 300.
117. Weyerstahl P, Kaul VK, Weirauch M, Marschall WH. (1987). Volatile constituents of Artemisia vestita oil. Planta Med, 53, 66-72.
118. Woerdenbag HJ, Pras N, Chan NG, Bang BT, Bos R, Van Uden W, Van Y P, Van Boi N, Batterman S, Lugt CB. (1994). Artemisinin, related sesquiterpenes and essential oil in Artemisia annua during a vegetation period in Vietnam. Planta Med, 60, 272-275.
119. Wu TS, Tsang ZJ, Wu PL, Lin FW, Li CY, Teng CM, Leec KH. (2001). New constituents and antiplatelet aggregation and anti-HIV principles of Artemisia capillaris. Bioorg Med Chem, 9, 77-83.
120. Xie G, Schepetkin IA, Siemsen DW, Kirpotina LN, Wiley JA, Quinn MT. (2008). Fractionation and characterization of biologically active polysaccharides from Artemisia tripartita. Phytochemistry, 69, 1359-1371.
121. Ye Y, Fang-Yuan G, Xing-Xin W, Yang S, Yi-Hua L, Ting C. (2008). Anti-infammatory and immunosuppressive effect of favones isolated from Artemisia vestita. J Ethnopharmacol, 120, 1-6.
122. Yeung HC. (1985). Handbook of Chinese Herbs and Formulas. Los Angeles: Institute of Chinese Medicine, 455.
123. Zhang Y, Zhang J, Yao J, Yang YL, Wang L, Dong LN. (2005). Studies on the chemical constituents of the essential oil of Artemisia dracunculus. Chinese Materia Med, 30, 594-596.
124. Zheng WF, Tan RX, Yang L, Liu ZL. (1996). Two favones from Artemisia giraldii and their antimicrobial activity. Planta Medica, 62, 160-162.