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Volumn 37, Issue 12, 2010, Pages 1241-1248

Do we need new antibiotics? The search for new targets and new compounds

Author keywords

Antibiotic resistance; Antibiotics; Biosynthesis; Infectious diseases; Search for new compounds

Indexed keywords

AMINO ACID TRANSFER RNA LIGASE; ANTIBIOTIC AGENT; FATTY ACID; FOLIC ACID; LIPID A; NATURAL PRODUCT; PEPTIDE DEFORMYLASE INHIBITOR; PEPTIDOGLYCAN; POLYKETIDE SYNTHASE; TEICHOIC ACID;

EID: 78651269003     PISSN: 13675435     EISSN: 14765535     Source Type: Journal    
DOI: 10.1007/s10295-010-0849-8     Document Type: Conference Paper
Times cited : (61)

References (50)
  • 1
    • 26444491047 scopus 로고    scopus 로고
    • Resistance to antibiotics: Are we in the postantibiotic era?
    • Alanis AJ (2005) Resistance to antibiotics: are we in the postantibiotic era? Arch Med Res 35:607-705
    • (2005) Arch. Med. Res. , vol.35 , pp. 607-705
    • Alanis, A.J.1
  • 3
    • 77949569493 scopus 로고    scopus 로고
    • Antibiotic resistance and its cost: Is it possible to reverse resistance?
    • Andersson DI, Hughes D (2010) Antibiotic resistance and its cost: is it possible to reverse resistance? Nat Rev Microbiol 8:260-271
    • (2010) Nat. Rev. Microbiol. , vol.8 , pp. 260-271
    • Andersson, D.I.1    Hughes, D.2
  • 4
    • 67349209853 scopus 로고    scopus 로고
    • Next-generation DNA sequencing techniques
    • Ansorge WJ (2009) Next-generation DNA sequencing techniques. New Biotechnol 25:195-203
    • (2009) New Biotechnol. , vol.25 , pp. 195-203
    • Ansorge, W.J.1
  • 5
    • 35448957251 scopus 로고    scopus 로고
    • Antimicrobials from actinomycetes: Back to the future
    • Baltz RH (2007) Antimicrobials from actinomycetes: back to the future. Microbe 2:125-131
    • (2007) Microbe , vol.2 , pp. 125-131
    • Baltz, R.H.1
  • 6
    • 54849405130 scopus 로고    scopus 로고
    • Renaissance in antibacterial discovery from actinomycetes
    • Baltz RH (2008) Renaissance in antibacterial discovery from actinomycetes. Curr Opinion Pharmacol 8:557-563
    • (2008) Curr. Opinion Pharmacol. , vol.8 , pp. 557-563
    • Baltz, R.H.1
  • 9
    • 4243689985 scopus 로고    scopus 로고
    • Organic lab sparks drug discovery
    • Borman S (2002) Organic lab sparks drug discovery. Chem Eng News 80(2):23-24
    • (2002) Chem. Eng. News , vol.80 , Issue.2 , pp. 23-24
    • Borman, S.1
  • 12
    • 64249095577 scopus 로고    scopus 로고
    • Analyzing the regulation of antibiotic production in streptomycetes
    • Bibb M, Hesketh A (2009) Analyzing the regulation of antibiotic production in streptomycetes. Methods Enzymol 458:93-116
    • (2009) Methods Enzymol. , vol.458 , pp. 93-116
    • Bibb, M.1    Hesketh, A.2
  • 13
    • 14944375311 scopus 로고    scopus 로고
    • New targets and screening approaches in antimicrobial drug discovery
    • Brown ED, Wright DW (2005) New targets and screening approaches in antimicrobial drug discovery. Chem Rev 105:759-774
    • (2005) Chem. Rev. , vol.105 , pp. 759-774
    • Brown, E.D.1    Wright, D.W.2
  • 15
    • 2942576144 scopus 로고    scopus 로고
    • The soil metagenome-a rich resource for the discovery of novel natural products
    • Daniel R (2005) The soil metagenome-a rich resource for the discovery of novel natural products. Curr Opin Biotechnol 15:199-204
    • (2005) Curr. Opin. Biotechnol. , vol.15 , pp. 199-204
    • Daniel, R.1
  • 16
    • 34447097735 scopus 로고    scopus 로고
    • Microbes have the last word. A drastic re-evaluation of antimicrobial treatment is needed to overcome the threat of antibiotic resistant bacteria
    • Davies J (2007) Microbes have the last word. A drastic re-evaluation of antimicrobial treatment is needed to overcome the threat of antibiotic resistant bacteria. EMBO Rep 8:616-621
    • (2007) EMBO Rep. , vol.8 , pp. 616-621
    • Davies, J.1
  • 17
    • 62449089680 scopus 로고    scopus 로고
    • Microbial drug discovery: 80 years of progress
    • Demain AL, Sanchez S (2009) Microbial drug discovery: 80 years of progress. J Antibiot 62:5-16
    • (2009) J. Antibiot. , vol.62 , pp. 5-16
    • Demain, A.L.1    Sanchez, S.2
  • 18
    • 0037208308 scopus 로고    scopus 로고
    • Property distributions: Differences between drug, natural products, and molecules from combinatorial chemistry
    • Feher M, Schmidt JM (2003) Property distributions: differences between drug, natural products, and molecules from combinatorial chemistry. J Chem Inf Comput Sci 43:218-227
    • (2003) J. Chem. Inf Comput. Sci. , vol.43 , pp. 218-227
    • Feher, M.1    Schmidt, J.M.2
  • 19
    • 33751100882 scopus 로고    scopus 로고
    • Developing a new resource for drug discovery: Marine actinomycete bacteria
    • Fenical W, Jensen PR (2006) Developing a new resource for drug discovery: marine actinomycete bacteria. Nat Chem Biol 2:666-673
    • (2006) Nat. Chem. Biol. , vol.2 , pp. 666-673
    • Fenical, W.1    Jensen, P.R.2
  • 20
    • 70449701942 scopus 로고    scopus 로고
    • Sense from sequence reads: Methods for aligment and assembly
    • Flicek P, Birney E (2009) Sense from sequence reads: methods for aligment and assembly. Nat Methods 6: S6-S12
    • (2009) Nat. Methods , vol.6
    • Flicek, P.1    Birney, E.2
  • 22
    • 33845653671 scopus 로고    scopus 로고
    • Soil to genomics: The Streptomyces chromosome
    • Hopwood DA (2006) Soil to genomics: the Streptomyces chromosome. Ann Rev Genet 40:1-23
    • (2006) Ann. Rev. Genet. , vol.40 , pp. 1-23
    • Hopwood, D.A.1
  • 23
    • 33846628530 scopus 로고    scopus 로고
    • How do antibiotic-producing bacteria ensure their self-resistance before antibiotic biosynthesis incapacitates them
    • Hopwood DA (2007) How do antibiotic-producing bacteria ensure their self-resistance before antibiotic biosynthesis incapacitates them. Mol Microbiol 63:937-940
    • (2007) Mol. Microbiol. , vol.63 , pp. 937-940
    • Hopwood, D.A.1
  • 24
    • 34447521845 scopus 로고    scopus 로고
    • Therapeutic treasures from the deep
    • Hopwood DA (2007) Therapeutic treasures from the deep. Nat Chem Biol 3:457-458
    • (2007) Nat. Chem. Biol. , vol.3 , pp. 457-458
    • Hopwood, D.A.1
  • 26
    • 7244251646 scopus 로고    scopus 로고
    • Research and development of new vaccines against infectious diseases
    • Kieny MP, Excler JL, Girard M (2004) Research and development of new vaccines against infectious diseases. Am J Public Health 94:1931-1935
    • (2004) Am. J. Public Health , vol.94 , pp. 1931-1935
    • Kieny, M.P.1    Excler, J.L.2    Girard, M.3
  • 27
    • 55249104697 scopus 로고    scopus 로고
    • Low hanging fruit in infectious disease drug development
    • Kraus CH (2008) Low hanging fruit in infectious disease drug development. Curr Opin Microbiol 11:434-438
    • (2008) Curr. Opin. Microbiol. , vol.11 , pp. 434-438
    • Kraus, C.H.1
  • 28
    • 67650447476 scopus 로고    scopus 로고
    • Fifteen years of microbial genomics: Meeting the challenges and fulfilling the dream
    • Kyrpides NC (2009) Fifteen years of microbial genomics: meeting the challenges and fulfilling the dream. Nat Biotechnol 27:627-632
    • (2009) Nat. Biotechnol. , vol.27 , pp. 627-632
    • Kyrpides, N.C.1
  • 29
    • 77749296117 scopus 로고    scopus 로고
    • Genome update: The 1000th genome-cautionary tale
    • Lagesen KW, Ussery DW, Wassenaar TM (2010) Genome update: the 1000th genome-cautionary tale. Microbiology 156:603-608
    • (2010) Microbiology , vol.156 , pp. 603-608
    • Lagesen, K.W.1    Ussery, D.W.2    Wassenaar, T.M.3
  • 31
    • 39649107354 scopus 로고    scopus 로고
    • Bacterial and fungal biofilm infections
    • Lynch AS, Robertson GT (2008) Bacterial and fungal biofilm infections. Ann Rev Med 59:415-428
    • (2008) Ann. Rev. Med. , vol.59 , pp. 415-428
    • Lynch, A.S.1    Robertson, G.T.2
  • 32
    • 0019292120 scopus 로고
    • Control of antibiotic biosynthesis
    • Martin JF, Demain AL (1980) Control of antibiotic biosynthesis. Microbiol Rev 44:230-251
    • (1980) Microbiol. Rev. , vol.44 , pp. 230-251
    • Martin, J.F.1    Demain, A.L.2
  • 35
    • 65249146929 scopus 로고    scopus 로고
    • Multidrug resistance in bacteria
    • Nikaido H (2009) Multidrug resistance in bacteria. Ann Rev Biochem 78:119-146
    • (2009) Ann. Rev. Biochem. , vol.78 , pp. 119-146
    • Nikaido, H.1
  • 37
    • 38149121365 scopus 로고    scopus 로고
    • Discovery and molecular engineering of sugar-containing natural product biosynthetic pathways in actinomycetes
    • Oh T-J, Mo SJ, Yoon YJ, Sohng JK (2007) Discovery and molecular engineering of sugar-containing natural product biosynthetic pathways in actinomycetes. J Microbiol Biotechnol 17:1909-1921
    • (2007) J. Microbiol. Biotechnol. , vol.17 , pp. 1909-1921
    • Oh, T.-J.1    Mo, S.J.2    Yoon, Y.J.3    Sohng, J.K.4
  • 38
    • 33644549679 scopus 로고    scopus 로고
    • The historical delivery of antibiotics from microbial natural products-can history repeat?
    • Peláez F (2006) The historical delivery of antibiotics from microbial natural products-can history repeat? Biochem Pharmacol 71:981-990
    • (2006) Biochem. Pharmacol. , vol.71 , pp. 981-990
    • Peláez, F.1
  • 39
    • 85047689741 scopus 로고    scopus 로고
    • Bacterial symbionts: Prospects for the sustainable production of invertebrate-derived pharmaceuticals
    • Piel J (2006) Bacterial symbionts: prospects for the sustainable production of invertebrate-derived pharmaceuticals. Curr Med Chem 13:39-50
    • (2006) Curr. Med. Chem. , vol.13 , pp. 39-50
    • Piel, J.1
  • 40
    • 58149161724 scopus 로고    scopus 로고
    • Genome and proteome annotation: Organization, interpretation and integration
    • Reeves GA, Talavera D, Thornton JM (2009) Genome and proteome annotation: organization, interpretation and integration. J R Soc Interface 6:129-147
    • (2009) J. R Soc. Interface , vol.6 , pp. 129-147
    • Reeves, G.A.1    Talavera, D.2    Thornton, J.M.3
  • 41
    • 78651293185 scopus 로고    scopus 로고
    • Report from the American Academy of Microbiology, 2009
    • Report from the American Academy of Microbiology, 2009
  • 43
    • 44049094415 scopus 로고    scopus 로고
    • Biocomputational strategies for microbial drug target identification
    • Champney WS ed, Humana, Totowa, New Jersey, USA
    • Sakharkar KR, Sakharkar MK, Chow V T K (2008) Biocomputational strategies for microbial drug target identification. In: Champney WS (ed) New antibiotic targets. Humana, Totowa, New Jersey, USA, pp 1-9
    • (2008) New Antibiotic Targets , pp. 1-9
    • Sakharkar, K.R.1    Sakharkar, M.K.2    Chow, V.T.K.3
  • 44
    • 51249163597 scopus 로고
    • Some aspects of overproduction of secondary metabolites
    • Spížek J, Tichý P (1995) Some aspects of overproduction of secondary metabolites. Folia Microbiol 40:43-50
    • (1995) Folia Microbiol. , vol.40 , pp. 43-50
    • Spížek, J.1    Tichý, P.2
  • 48
    • 14844366787 scopus 로고    scopus 로고
    • Introduction: Antibiotic resistance
    • Walsh CF, Wright G (2005) Introduction: antibiotic resistance. Chem Rev 105:391-393
    • (2005) Chem. Rev. , vol.105 , pp. 391-393
    • Walsh, C.F.1    Wright, G.2
  • 49
    • 67650388245 scopus 로고    scopus 로고
    • Squashing superbugs-the race for new antibiotics
    • Walsh CT, Fischbach MA (2009) Squashing superbugs-the race for new antibiotics. Sci Amer Mag 301(1):44-51
    • (2009) Sci. Amer. Mag. , vol.301 , Issue.1 , pp. 44-51
    • Walsh, C.T.1    Fischbach, M.A.2
  • 50
    • 0034752042 scopus 로고    scopus 로고
    • How many antibiotics are produced by the genus Streptomyces?
    • Watve MG, Tickoo R, Jog MM, Rhole BD (2001) How many antibiotics are produced by the genus Streptomyces? Arch Microbiol 176:386-390
    • (2001) Arch. Microbiol. , vol.176 , pp. 386-390
    • Watve, M.G.1    Tickoo, R.2    Jog, M.M.3    Rhole, B.D.4


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