Dexmedetomidine-related atrial standstill and loss of capture in a pediatric patient after congenital heart surgery

Critical Care Medicine

Volumn 39, Issue 1, 2011, Pages 187-189

  Shepard, Suzanne M ^a   Tejman Yarden, Shai ^a   Khanna, Sandeep ^a   Davis, Christopher K ^a   Batra, Anjan S ^b  

^a RADY CHILDREN'S HOSPITAL   (United States)

^b CHILDREN S HOSPITAL OF ORANGE COUNTY   (United States)

Author keywords

atrial standstill; congenital heart disease; dexmedetomidine; pacemaker

Indexed keywords

CISATRACURIUM; DEXMEDETOMIDINE; FENTANYL; MIDAZOLAM;

ANALGESIA; ARTICLE; ARTIFICIAL VENTILATION; CASE REPORT; CHILD; COMPLETE HEART BLOCK; DRUG WITHDRAWAL; ECHOCARDIOGRAPHY; EXTUBATION; FALLOT TETRALOGY; FEMALE; HEART ARREST; HEART ATRIUM FLUTTER; HEART PACING; HEART RATE; HEART SURGERY; HUMAN; INTENSIVE CARE; MAZE TEST; MITRAL VALVE REGURGITATION; MITRAL VALVE REPLACEMENT; P WAVE; PACEMAKER; PARALYSIS; PRESCHOOL CHILD; PRIORITY JOURNAL; PULMONARY VALVE REPLACEMENT; SEDATION; SINUS NODE DYSFUNCTION; TRICUSPID VALVE REGURGITATION; TRICUSPID VALVE REPAIR;

EID: 78651258998     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e3181feb4b3     Document Type: Article

References (16)

1. Bloor BC, Ward DS, Belleville JP, et al: Effects of intravenous dexmedetomidine in humans. II. Hemodynamic changes. Anesthesiology 1992;77:1134-1142
2. Tobias JD: Dexmedetomidine: Applications in pediatric critical care and pediatric anesthesiology. Pediatr Crit Care Med 2007;8:115-131
3. Bejian S, Valasek C, Nigro JJ, et al: Prolonged use of dexmedetomidine in the paediatric cardiothoracic intensive care unit. Cardiol Young 2009;19:98-104
4. Mukhtar AM, Obayah EM, Hassona AM: The use of braycardia during sedation with dexmedetomidine in pediatric cardiac surgery. Anesth Analg 2006;103:52-56
5. Chrysostomou C, Di Filippo S, Manrique AM, et al: Use of dexmedetomidine in children after cardiac and thoracic surgery. Pediatr Crit Care Med 2006;7:126-131
6. Wijeysundera DN, Naik JS, Beattie WS: Alpha- 2 adrenergic agonists to prevent perioperative cardiovascular complications: A meta analysis. Am J Med 2003;114:742-752
7. Zhang X, Schmidt U, Wain JC, et al: Bradycardia leading to asystole during dexmedetomidine infusion in an 18 year-old doublelung transplant recipient. J Clin Anesth 2010;22:1-2
8. Siobal MS, Kallet RH, Kivett VA, et al: Use of dexmedetomidine to facilitate extubation in surgical intensive-care-unit patients who failed previous weaning attempts following prolonged mechanical ventilation: A pilot study. Respir Care 2006;51:492-496
9. Riker RR, Shehabi Y, Bokesh PM, et al;SEDCOM (Safety and Efficacy of Dexmedetomidine Compared With Midazolam) Study Group: Dexmedetomidine vs midazolam for sedation of critically ill patients: A randomized trial. JAMA 2009;301:489-499
10. Petroz GC, Sikich N, James M, et al: A phase I, two-center study of the pharmacokinetics and pharmacodynamics of dexmedetomidine in children. Anesthesiology 2006;105: 1098-1110
11. Gerlach AT, Dasta JF: Dexmedetomidine: An updated review. Ann Pharmacother 2007;41: 245-252
12. Díaz SM, Rodarte A, Foley J, et al: Pharmacokinetics of dexmedetomidine in postsurgical pediatric intensive care unit patients: Preliminary study. Pediatr Crit Care Med 2007;8:419-424
13. Tobin JR, Shafer SL, Davis PJ: Pediatric research and scholarship: Another Gordian knot? Anesth Analg 2006;103:43-48
14. Shah AN, Koneru J, Nicoara A, et al: Dexmedetomidine related cardiac arrest in a patient with permanent pacemaker;a cautionary tale. Pace 2007;30:1158-1160
15. Ingersoll-Weng E, Mancke GR, Thistlethwaite PA: Dexmedetomidine and cardiac arrest. Anesthesiology 2004;100:738-739
16. Naranjo CA, Busto U, Sellers EM, et al: A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981;30:239-245 (Pubitemid 12149145)