Mitochondrial dysfunction due to Leber's hereditary optic neuropathy as a cause of visual loss during assessment for epilepsy surgery

Epilepsy and Behavior

Volumn 20, Issue 1, 2011, Pages 38-43

  Niehusmann, Pitt ^a   Surges, Rainer ^a   von Wrede, Randi D ^a   Elger, Christian E ^a   Wellmer, Jörg ^a   Reimann, Jens ^a   Urbach, Horst ^a   Vielhaber, Stefan ^b   Bien, Christian G ^a   Kunz, Wolfram S ^a  

^a UNIVERSITY OF BONN   (Germany)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

Epilepsy; Leber's hereditary optic neuropathy; Mitochondria; Visual disturbance; Wada test

Indexed keywords

AMOBARBITAL; CITRATE SYNTHASE; CYTOCHROME C OXIDASE; GLUTAMIC ACID; MALIC ACID; MITOCHONDRIAL DNA; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); TECHNETIUM;

ADULT; ARTICLE; BRAIN TISSUE; CASE REPORT; CHEMOSENSITIVITY; CLINICAL ASSESSMENT; COMPLEX PARTIAL SEIZURE; CONTROLLED STUDY; DEPRESSION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ELECTRODE; ELECTROENCEPHALOGRAPHY; ELECTRORETINOGRAPHY; ENZYME ACTIVITY; EVOKED VISUAL RESPONSE; FEMALE; GASTROENTERITIS; GENE AMPLIFICATION; GENE MUTATION; GENETIC ANALYSIS; HOMONYMOUS HEMIANOPIA; HUMAN; HUMAN TISSUE; IMPLANTATION; INSULIN DEPENDENT DIABETES MELLITUS; LEBER HEREDITARY OPTIC NEUROPATHY; MAGNETIC RESONANCE ANGIOGRAPHY; MALE; MENTAL DEFICIENCY; MISSENSE MUTATION; MUSCLE TISSUE; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; OPHTHALMOSCOPY; OPTIC CHIASM; OPTIC TRACT; PERIMETRY; POLYMERASE CHAIN REACTION; PREOPERATIVE PERIOD; PSYCHOMOTOR DISORDER; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SCOTOMA; SEQUENCE ANALYSIS; TELEMETRY; TEMPORAL LOBE EPILEPSY; VISUAL ACUITY; VISUAL FIELD DEFECT; VISUAL IMPAIRMENT; VISUAL SYSTEM EXAMINATION;

ADULT; BLINDNESS; DNA, MITOCHONDRIAL; EPILEPSY; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MITOCHONDRIA; MUTATION; OPTIC ATROPHY, HEREDITARY, LEBER;

EID: 78651248711     PISSN: 15255050     EISSN: 15255069     Source Type: Journal    
DOI: 10.1016/j.yebeh.2010.11.008     Document Type: Article

References (17)

1. Haag A., Knake S., Hamer H.M., et al. The Wada test in Austrian, Dutch, German, and Swiss epilepsy centers from 2000 to 2005: a review of 1421 procedures. Epilepsy Behav 2008, 13:83-89.
2. Loddenkemper T., Morris H.H., Moddel G. Complications during the Wada test. Epilepsy Behav 2008, 13:551-553.
3. Tanriverdi T., Ajlan A., Poulin N., Olivier A. Morbidity in epilepsy surgery: an experience based on 2449 epilepsy surgery procedures from a single institution. J Neurosurg 2009, 110:1111-1123.
4. Kral T., Clusmann H., Urbach J., et al. Preoperative evaluation for epilepsy surgery (Bonn algorithm). Zentralbl Neurochir 2002, 63:106-110.
5. Kuznetsov A.V., Veksler V., Gellerich F.N., Saks V., Margreiter R., Kunz W.S. Analysis of mitochondrial function in situ in permeabilized muscle fibers, tissues and cells. Nat Protoc 2008, 3:965-976.
6. Wiedemann F.R., Vielhaber S., Schroder R., Elger C.E., Kunz W.S. Evaluation of methods for the determination of mitochondrial respiratory chain enzyme activities in human skeletal muscle samples. Anal Biochem 2000, 279:55-60.
7. Kunz W.S., Kudin A., Vielhaber S., Elger C.E., Attardi G., Villani G. Flux control of cytochrome c oxidase in human skeletal muscle. J Biol Chem 2000, 275:27741-27745.
8. Engel J.J. Surgical treatment of the epilepsies 1993, Raven Press, New York.
9. Malter M.P., Helmstaedter C., Urbach H., Vincent A., Bien C.G. Antibodies to glutamic acid decarboxylase define a form of limbic encephalitis. Ann Neurol 2010, 67:470-478.
10. Von Oertzen J., Klemm E., Urbach H., et al. SATSCOM-selective amobarbital test intraarterial SPECT coregistered to MRI: description of a method assessing selective perfusion. Neuroimage 2000, 12:617-622.
11. Blümcke I., Pauli E., Clusmann H., et al. A new clinico-pathological classification system for mesial temporal sclerosis. Acta Neuropathol 2007, 113:235-244.
12. Newman N.J. Hereditary optic neuropathies: from the mitochondria to the optic nerve. Am J Ophthalmol 2005, 140:517-523.
13. Kudin A.P., Zsurka G., Elger C.E., Kunz W.S. Mitochondrial involvement in temporal lobe epilepsy. Exp Neurol 2009, 218:326-332.
14. Nikoskelainen E.K., Marttila R.J., Huoponen K., et al. Leber's "plus": neurological abnormalities in patients with Leber's hereditary optic neuropathy. J Neurol Neurosurg Psychiatry 1995, 59:160-164.
15. Grazina M.M., Diogo L.M., Garcia P.C., et al. Atypical presentation of Leber's hereditary optic neuropathy associated to mtDNA 11778G>A point mutation: a case report. Eur J Paediatr Neurol 2007, 11:115-118.
16. Brown M.D., Zhadanov S., Allen J.C., et al. Novel mtDNA mutations and oxidative phosphorylation dysfunction in Russian LHON families. Hum Genet 2001, 109:33-39.
17. Micic D., Klatzo I., Spatz M. The effect of sodium pentobarbital on some mitochondrial enzymes. J Neurochem 1978, 30:1627-1628.