Ivermectin and Milbemycin Oxime in Experimental Adult Heartworm (Dirofilaria immitis) Infection of Dogs

Journal of Veterinary Internal Medicine

Volumn 25, Issue 1, 2011, Pages 61-64

  Snyder, D E ^a   Wiseman, S ^b   Cruthers, L R ^c   Slone, R L ^c  

^a ELANCO ANIMAL HEALTH   (United States)

^b ELI LILLY AND COMPANY   (United States)

^c Professional Laboratory Research Services   (United States)

Author keywords

Canine; Chemoprophylaxis; Effectiveness; Macrocyclic lactone

Indexed keywords

ANTIPARASITIC AGENT; IVERMECTIN; MACROLIDE; MILBEMYCIN OXIME;

ANIMAL; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIROFILARIA IMMITIS; DIROFILARIASIS; DOG; DOG DISEASE; FEMALE; GROWTH, DEVELOPMENT AND AGING; MALE; PARASITOLOGY; RANDOMIZED CONTROLLED TRIAL;

ANIMALS; ANTIPARASITIC AGENTS; DIROFILARIA IMMITIS; DIROFILARIASIS; DOG DISEASES; DOGS; FEMALE; IVERMECTIN; MACROLIDES; MALE;

CANIS FAMILIARIS; DIROFILARIA IMMITIS;

EID: 78651246074     PISSN: 08916640     EISSN: 19391676     Source Type: Journal    
DOI: 10.1111/j.1939-1676.2010.0657.x     Document Type: Article

References (10)

1. Bowman DD, Atkins CE. Heartworm biology, treatment, and control. Vet Clin North Am Small Anim Pract 2009;39:1127-1158.
2. Hampshire VA. Evaluation of efficacy of heartworm preventive products at the FDA. Vet Parasitol 2005;133:191-195.
3. McCall JW, Lindemann BA, Porter CA. Prophylactic activity of avermectins against experimentally induced Dirofilaria immitis infections in dogs. In: Otto G.F., ed. Proceedings of the Heartworm Symposium '80. Edwardsville, KS: Veterinary Medicine Publishing Co; 1980:126-130.
4. McCall JW. The safety-net story about macrocyclic lactone heartworm preventives: A review, an update, and recommendations. Vet Parasitol 2005;133:197-206.
5. Holmes RA, McCall JW, Prasse KW. Thiacetarsamide in dogs with Dirofilaria immitis: Influence of decreased liver function on drug efficacy. Am J Vet Res 1986;47:1341-1344.
6. Bowman D, Little SE, Lorentzen L, et al. Prevalence and geographic distribution of Dirofilaria immitis, Borrelia burgdorferi, Ehrlichia canis, and Anaplasma phagocytophilum in dogs in the United States: Results of a national clinic-based serologic survey. Vet Parasitol 2009;160:138-148.
7. Blagburn BL. Heartworms: Are we losing the war? Is there resistance? Western Veterinary Conference, Las Vegas, NV, 2010.
8. American Heartworm Society Meeting. 2010. Available at: Accessed November 17, 2010.
9. Osei-Atwenoboana MY, Eng JK, Boakye DA, et al. Prevalence and intensity of Onchocerca volvulus infection and efficacy of ivermectin in endemic communities in Ghana: A two-phase epidemiological study. Lancet 2007;369:2021-2029.
10. Wolstenholme AJ, Fairweather I, Prichard R, et al. Drug resistance in veterinary helminths. Trends Parasitol 2004;20:469-476.