Prevalence and geographic distribution of Dirofilaria immitis, Borrelia burgdorferi, Ehrlichia canis, and Anaplasma phagocytophilum in dogs in the United States: Results of a national clinic-based serologic survey

Veterinary Parasitology

Volumn 160, Issue 1-2, 2009, Pages 138-148

  Bowman, Dwight ^a   Little, Susan E ^b   Lorentzen, Leif ^c   Shields, James ^c   Sullivan, Michael P ^c   Carlin, Ellen P ^a  

^a C4 119 Veterinary Medical Center ^*  (United States)

^b OKLAHOMA STATE UNIVERSITY   (United States)

^c IDEXX LABORATORIES   (United States)

Author keywords

Anaplasma; Anaplasmosis; Antigen test; Borrelia burgdorferi; Canine; Dirofilaria immitis; Dirofilariasis; Ehrlichia; Ehrlichiosis; ELISA; Heartworm; Lyme borreliosis

Indexed keywords

PARASITE ANTIBODY; PARASITE ANTIGEN;

ANAPLASMA PHAGOCYTOPHILUM; ARTICLE; BORRELIA BURGDORFERI; DIROFILARIA IMMITIS; DOG; EHRLICHIA CANIS; ENDEMIC DISEASE; EVALUATION; GEOGRAPHIC DISTRIBUTION; NONHUMAN; PARASITE TRANSMISSION; PREVALENCE; SEROLOGY; UNITED STATES;

ANAPLASMA PHAGOCYTOPHILUM; ANIMALS; BORRELIA BURGDORFERI; DIROFILARIA IMMITIS; DIROFILARIASIS; DOG DISEASES; DOGS; EHRLICHIA CANIS; EHRLICHIOSIS; LYME DISEASE; PARASITIC DISEASES, ANIMAL; PREVALENCE; SEROEPIDEMIOLOGIC STUDIES; UNITED STATES;

ANAPLASMA; ANAPLASMA PHAGOCYTOPHILUM; ANIMALIA; BORRELIA BURGDORFERI; CANIS FAMILIARIS; DIROFILARIA IMMITIS; EHRLICHIA; EHRLICHIA CANIS;

EID: 59849114422     PISSN: 03044017     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetpar.2008.10.093     Document Type: Article

References (61)

1. Adelson M.E., Rao R.V., Tilton R.C., Cabets K., Eskow E., Fein L., Occi J.L., and Mordechai E. Prevalence of Borrelia burgdorferi, Bartonella spp., Babesia microti, and Anaplasma phagocytophila in Ixodes scapularis ticks collected in Northern New Jersey. J. Clin. Microbiol. 42 (2004) 2799-2801
2. ® Test kit insert.
3. APPMA, 2004. American Pets Products Manufacturers Association National Pet Owners Survey, p. 18.
4. Atkins C.E. Comparison of results of three commercial heartworm antigen test kits in dogs with low heartworm burdens. JAVMA 222 (2003) 1221-1223
5. Blagburn B.L., Lindsay D.S., Vaughn J.K., Rippey N.S., Wright J.C., Lynn R.C., Kelch W.J., Ritchie G.C., and Hepler D.I. Prevalence of canine parasites based on fecal flotation. Comp. Cont. Ed. Pract. Vet. 18 (1996) 483-509
6. Bowman D.D. Georgi's Parasitology for Veterinarians. 8th ed. (2003), Saunders, Philadelphia, PA 422 pp
7. Bowman D.D., Torre C.J., and Mannella C. Survey of 11 Western states for Heartworm (Dirofilaria immitis) infection, Heartworm diagnostic protocols, and fecal examination protocols for gastrointestinal parasites. Vet. Ther. 8 (2007) 293-304
8. Bown K.J., Begon M., Bennett M., Woldehiwet Z., and Ogden N.H. Seasonal dynamics of Anaplasma phagocytophila in a rodent-tick (Ixodes trianguliceps) sytem, United Kingdom. Emerg. Infect. Dis. 9 (2003) 63-70
9. Brandsma A.R., Little S.E., Lockhart J.M., Davidson W.R., Stallknecht D.E., and Dawson J.E. Novel Ehrlichia organism in white-tailed deer associated with lone star tick parasitism. J. Med. Entomol. 36 (1999) 190-194
10. Brisson D., Dykhuizen D.E., and Ostfeld R.S. Conspicuous impacts of inconspicuous hosts on the Lyme disease epidemic. Proc. Biol. Sci. 2008 (2008) 227-235
11. Centers for Disease Control and Prevention, 2007a. Lyme Disease, United States, 2003-2005. Morb. Mortal. Wkly. Rpt. 56, 573-576 (June 15).
12. Centers for Disease Control and Prevention, 2007b. Table 1: provisional cases of infrequently reported notifiable diseases. Morb. Mortal. Wkly. Rpt. 56, 771 (August 3).
13. Centers for Disease Control and Prevention, 2007c. Table 2: provisional cases of selected notifiable diseases, United States. Morb. Mortal. Wkly. Rpt. 56, 775 (August 3).
14. Centers for Disease Control and Prevention, Nationally Notifiable Infectious Diseases, United States, 2007d. http://www.cdc.gov/epo/dphsi/phs/infdis2007r.htm. Accessed August 24, 2007.
15. ®, for the detection of antibodies to canine granulocytic infection, Anaplasma phagocytophilium. Research Abstract of the 25th Annual ACVIM Forum. Seattle, WA, June (2007)
16. Clark K. Borrelia species in host-seeking ticks and small mammals in Florida. J. Clin. Microbiol. 42 (2004) 5076-5086
17. Corselli N.J., and Platzer E.G. Canine heartworm: disease focus along the lower Colorado river. Proceedings of the 49th Annual Conference of the California Mosquito and Vetor Control Association. April 26-29, 1981 (1982) 5-8
18. Courtney J.W., Dryden R.L., Montgomery J., Schneider B.S., Smith G., and Massung R.F. Molecular characterization of Anaplasma phagocytophilum and Borrelia burgdorferi in Ixodes scapularis ticks from Pennsylvania. J. Clin. Microbiol. 41 (2003) 1569-1573
19. Courtney C.H., and Zeng Q.Y. Comparison of heartworm antigen test kit performance in dogs having low heartworm burdens. Vet. Parasitol. 96 (2001) 317-322
20. Daniels T.J., Boccia T.M., Varde S., Marcus J., Le J.H., Bucher D.J., Falco R.C., and Schwartz I. Geographic risk for Lyme disease and human granulocytic ehrlichiosis in Southern New York State. Appl. Environ. Microbiol. 64 (1998) 4663-4669
21. Dennis D.T. Rash decisions: Lyme disease, or not?. Clin. Infect. Dis. 41 (2005) 966-968 (Editorial Commentary)
22. 6 antibodies in dogs from southeastern and mid-Atlantic states. Vector Borne Zoonotic Dis. 4 (2004) 221-229
23. Eisen R.J., Mun J., Eisen L., and Lane R.S. Life stage-related differences in density of questing ticks and infection with Borrelia burgdorferi sensu lato within a single cohort of Ixodes pacificus (Acari: Ixodidae). J. Med. Entomol. 41 (2004) 768-773
24. Foley J.E., Barlough J.E., Kimsey R.B., Madigan J.E., DeRock E., and Poland A. Ehrlichia spp. in cervids from California. J. Wildl. Dis. 34 (1998) 731-737
25. Fritz C.L., Bronson L.R., Smith C.R., Crawford-Miksza L., Yeh E., and Schnurr D. Clinical, epidemiologic, and environmental surveillance for ehrlichiosis and anaplasmosis in an endemic area of northern California. J. Vector Ecol. 30 (2005) 4-10
26. Groves M.G., Dennis G.L., Amyx H.L., and Huxsoll D.L. Transmission of Ehrlichia canis to dogs by ticks (Rhipicephalus sanguineus). Am. J. Vet. Res. 36 (1975) 937-940
27. Guerrero J., Nelson C.T., and Carithers D.S. Results and realistic implications of the 2004 AHS-Merial heartworm survey. Proc. AAVP 51st Ann. Meeting (2006) 62-63
28. Harvey J.W. Thrombocytotropic anaplasmosis (A. platys infection). In: Greene C. (Ed). Greene's Infectious Diseases of the Dog and Cat (2006), Saunders Elsevier, St. Louis, MO 229-231
29. Holman M.S., Caporale D.A., Goldberg J., Lacombe E., Lubelczyk C., Rand P.W., and Smith R.P. Anaplasma phagocytophilum, Babesia microti, and Borrelia burgdorferi in Ixodes scapularis, southern coastal Maine. Emerg. Infect. Dis. 10 (2004) 744-746
30. Johnson E.M., Ewing S.A., Barker R.W., Fox J.C., and Kocan K.M. Experimental transmission of Ehrlichia canis by Dermacentor variabilis. Vet. Parasitol. 74 (1998) 277-288
31. In: Kahn C.M. (Ed). The Merck Veterinary Manual. 9th ed. (2005), Merck and Co., Inc., White house Station, NJ 2712 pp
32. Kramer V.L., Randolph M.P., Hui L.T., Irwin W.E., Gutierrez A.G., and Vugia D.J. Detection of the agents of human ehrlichioses in ixodid ticks from California. Am. J. Trop. Med. Hyg. 60 (1999) 62-65
33. Lagrotteria D.D., Crowther M.A., Lee C.H., and Peregrine A. A 44-year-old woman with dry cough and solitary nodule. Can. Med. Assoc. J. 169 (2003) 696-697
34. Lane R.S., Foley J.E., Eisen L., Lennette E.T., and Peot M.A. Acarologic risk of exposure to emerging tick-borne bacterial pathogens in a semirural community in northern California. Vector Borne Zoonotic Dis. 1 (2001) 197-210
35. Lewis G.E., Ristic M., Smith R.D., Lincoln T., and Stephenson E.H. The brown dog tick Rhipicephalus sanguineus and the dog as experimental hosts of Ehrlichia canis. Am. J. Vet. Res. 38 (1977) 1953-1955
36. Loftis A.D., Reeves W.K., Spurlock J.P., Mahan S.M., Troughton D.R., Dasch G.A., and Levin M.L. Infection of a goat with a tick-transmitted Ehrlichia from Georgia, USA, that is closely related to Ehrlichia ruminantium. J. Vector Ecol. 31 (2006) 213-223
37. LoGiudice K., Ostfeld R.S., Schmidt K.A., and Keesing F. The ecology of infectious disease: effects of host diversity and community composition on Lyme disease risk. Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 567-571
38. Marques A.R., Martin D.S., and Philipp M.T. Evaluation of the C6 peptide enzyme-linked immunosorbent assay for individuals vaccinated with the recombinant OspA vaccine. J. Clin. Microbiol. 40 (2002) 2591-2593
39. Miller M.W., Atkins D.E., Stemme K., Robertson-Plouch C., and Guerrero J. Prevalence of exposure to Dirofilaria immitis in cats in multiple areas of the United States. Vet. Ther. 1 (2000) 169-175
40. Munderloh U.G., Yabsley M.J., Murphy S.M., Luttrell M.P., and Howerth E.W. Isolation and establishment of the raccoon Ehrlichia-like agent in tick cell culture. Vector Borne Zoonotic Dis. 7 (2007) 418-425
41. O'Connor T.P., Esty K.J., Machenry P., Hanscom J.L., Bartol B.A., and Lawton T. Performance evaluation of Ehrlichia canis and Borrelia burgdorferi peptides in a new Dirofilaria immitis combination assay. American Heartworm Society Triannual Symposium (2002) 77-84
42. O'Connor T.P., Esty K.J., Hanscom J.L., Shields P., and Philipp M.T. Dogs vaccinated with common Lyme disease vaccines do not respond to IR6, the conserved immunodominant region of the VlsE surface protein of Borrelia burgdorferi. Clin. Diagn. Lab. Immunol. 11 (2004) 458-462
43. O'Connor T.P., Hanscom J.L., Hegarty B.C., Groat R.G., and Breitschwerdt E.B. Comparison of an indirect immunofluorescence assay, western blot analysis, and a commercially available ELISA for detection of Ehrlichia canis antibodies in canine sera. Am. J. Vet. Res. 67 (2006) 206-210
44. Oliver Jr. J.H., Clark K.L., Chandler Jr. F.W., Tao L., James A.M., Banks C.W., Huey L.O., Banks A.R., Williams D.C., and Durden L.A. Isolation, cultivation, and characterization of Borrelia burgdorferi from rodents and ticks in the Charleston area of South Carolina. J. Clin. Microbiol. 38 (2000) 120-124
45. Oliver Jr. J.H., Lin T., Gao L., Clark K.L., Banks C.W., Durden L.A., James A.M., and Chandler Jr. F.W. An enzootic transmission cycle of Lyme borreliosis spirochetes in the southeastern United States. Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 11642-11645
46. Pensinger R.R. Fifteen-year observation of heartworm disease in Monterey Bay area of California. Proceedings of the Heartworm Symposium 1986 (1986) 135-138
47. Peregrine A.S. Rational use of diagnostic tests chapter 133. In: Ettinger S.J., and Feldman E.C. (Eds). Textbook of Veterinary Internal Medicine: Disease of the Dog and Cat. sixth edition vol. 1 (2005), Elsevier Saunders, St. Louis, MO 489-492
48. Peregrine A.S., Barker I.K., Abrams-Ogg A.C.G., and Woods J.P. Screening dogs in Ontario for Borrelia burgdorferi and Ehrlichia canis should be selective rather than routine (Letter to the Editor). Can. Vet. J. 48 (2007) 673
49. Rikihisa Y. The tribe Ehrlichieae and ehrlichial diseases. Clin. Microbiol. Rev. 4 (1991) 286-308
50. Rikihisa Y. New findings on members of the family Anaplasmataceae of veterinary importance. Ann. NY Acad. Sci. 1078 (2006) 438-445
51. Roy B.T., Chirurgi V.A., and Theis J.H. Pulmonary dirofilariasis in California. West. J. Med. 158 (1993) 74-76
52. Sacks B.N., Chomel B.B., and Kasten R.W. Modeling the distribution and abundance of the non-native parasite, canine heartworm, in California coyotes. OIKOS 105 (2004) 415-425
53. Schmidt K.A., and Ostfeld R.S. Biodiversity and the dilution effect in disease ecology. Ecology 82 (2001) 609-619
54. Steere A.C., Coburn J., and Glickstein L. The emergence of Lyme disease. J. Clin. Invest. 113 (2004) 1093-1101
55. Theis J.H. Public health aspects of Dirofilariasis in the United States. Vet. Parasitol. 133 (2005) 157-180
56. Theis J.H., Gilson A., Simon G.E., Bradshaw B., and Clark D. Case report: unusual location of Dirofilaria immitis in a 28-year-old man necessitates orchiectomy. Am. J. Trop. Med. Hyg. 64 (2001) 317-322
57. Tsao J.I., Wootton J.T., Bunikis J., Luna M.G., Fish D., and Barbour A.G. An ecological approach to preventing human infection: vaccinating wild mouse reservoirs intervenes in the Lyme disease cycle. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 18159-18164
58. Wang G., Liveris D., Brei B., Wu H., Falco R.C., Fish D., and Schwartz I. Real-time PCR for simultaneous detection and quantification of Borrelia burgdorferi in field-collected Ixodes scapularis ticks from the northeastern United States. Appl. Environ. Microbiol. 69 (2003) 4561-4565
59. Walters L.L., and Lavoipierre M.M.J. Vector potential of six mosquito species in landscapes of high heartworm endemicity in northern California. Proceedings and Papers of the 49th Annual Conference of the California Mosquito and Vector Control Association, Inc. Redding, CA, April 26-29, 1981 (1982) 9
60. Wormser G.P., Dattwyler R.J., Shapiro E.D., Halperin J.J., Steere A.C., Klempner M.S., Krause P.J., Bakken J.S., Strle F., Stanek G., Bockenstedt L., Fish D., Dumler J.S., and Nadelman R.B. The clinical assessment, treatment, and prevention of Lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America. Clin. Infect. Dis. 43 (2006) 1089-1134
61. Yabsley M.J., Wimberly M.C., Stallknecht D.E., Little S.E., and Davidson W.R. Spatial analysis of the distribution of Ehrlichia chaffeensis, causative agent of human monocytotropic ehrlichiosis, across a multi-state region. Am. J. Trop. Med. Hyg. 72 (2005) 840-850