A clinical review of aripiprazole in bipolar depression and maintenance therapy of bipolar disorder

Journal of Affective Disorders

Volumn 128, Issue SUPPL. 1, 2011, Pages

  Yatham, Lakshmi N ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Aripiprazole; Bipolar depression; Bipolar disorder; Maintenance therapy

Indexed keywords

ARIPIPRAZOLE; ATYPICAL ANTIPSYCHOTIC AGENT; LAMOTRIGINE; LITHIUM; OLANZAPINE; PLACEBO; QUETIAPINE; VALPROIC ACID;

ADJUVANT THERAPY; BIPOLAR DEPRESSION; BIPOLAR DISORDER; CLINICAL GLOBAL IMPRESSION SCALE; DOUBLE BLIND PROCEDURE; DRUG APPROVAL; DRUG DOSE COMPARISON; DRUG DOSE TITRATION; DRUG EFFICACY; DRUG MEGADOSE; DRUG WITHDRAWAL; EMERGENCY TREATMENT; EXTRAPYRAMIDAL SYMPTOM; FOOD AND DRUG ADMINISTRATION; HUMAN; LONG TERM CARE; MAINTENANCE THERAPY; MANIA; MENTAL DISEASE; MONOTHERAPY; MONTGOMERY ASBERG DEPRESSION RATING SCALE; POST HOC ANALYSIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RECURRENCE RISK; RELAPSE; REVIEW; STATISTICAL SIGNIFICANCE; SYMPTOM; SYSTEMATIC REVIEW; TREATMENT OUTCOME; YOUNG MANIA RATING SCALE;

EID: 78651238924     PISSN: 01650327     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0327(11)70005-2     Document Type: Article

References (46)

1. L.L. Altshuler, R.M. Post, D.O. Black, P.E. Keck Jr., W.A. Nolen, M.A. Frye, T. Suppes, H. Grunze, R.W. Kupka, G.S. Leverich, S.L. McElroy, J. Walden, J. Mintz Subsyndromal depressive symptoms are associated with functional impairment in patients with bipolar disorder: results of a large, multisite study J. Clin. Psychiatry. 67 2006 1441 1560
2. R.M. Berman, R.N. Marcus, R. Swanink, R.D. McQuade, W.H. Carson, P.K. Corey-Lisle, A. Khan The efficacy and safety of aripiprazole as adjunctive therapy in major depressive disorder: a multicenter, randomized, double-blind, placebo-controlled study J. Clin. Psychiatry. 68 2007 843 853
3. C.L. Bowden, E. Vieta, K.S. Ice, J.H. Schwartz, P.P. Wang, M. Versavel Ziprisidone plus a mood stabilizer in subjects with bipolar I disorder: a 6-month, randomized, placebo-controlled, double-blind trial J. Clin. Psychiatry. 71 2010 130 137
4. J.R. Calabrese, C.L. Bowden, G.S. Sachs, J.A. Ascher, E. Monaghan, G.D. Rudd A double-blind placebo controlled study of lamotrigine monotherapyin outpatients with bipolar I depression Lamictal 602 Study Group. J. Clin. Psychiatry 60 1999 79 88
5. J.R. Calabrese, E. Vieta, R. El-Mallakh, R.L. Findling, E.A. Youngstrom, O. Elhaj, P. Gajwani, R. Pies Mood state at study entry as predictor of the polarity of relapse in bipolar disorder Biol. Psychiatry 56 2004 957 963
6. J.R. Calabrese, P.E. Keck Jr., W. Macfadden, M. Minkwitz, T.A. Ketter, R.H. Weisler, A.J. Cutler, R. McCoy, E. Wilson, J. Mullen A randomized, double-blind, placebo-controlled trial of quetiapine in the treatment of bipolar I or II depression Am. J. Psychiatry 162 2005 1351 1360 (Pubitemid 40905587)
7. J.R. Calabrese, R.F. Huffman, R.L. White, S. Edwards, T.R. Thompson, J.A. Ascher, E.T. Monaghan, R.A. Leadbetter Lamotrigine in the acute treatment of bipolar depression: results of five double-blind, placebo-controlled clinical trials Bipolar Disord. 10 2008 323 333
8. th Annual Meeting of the New Clinical Drug Evaluation Unit, June 14-17, Boca Raton, FL.
9. N. Cruz, J. Sanchez-Moreno, F. Torres, J.M. Goikolea, M. Valenti, E. Vieta Efficacy of modern antipsychotics in placebo-controlled trials in bipolar depression: a meta-analysis Int. J. Neuropsychopharmacol. 13 2010 5 14
10. R.T. Dunn, V.A. Stan, L.S. Chriki, M.M. Filkowski, S.N. Ghaemi A prospective, open-label study of aripiprazole mono- and adjunctive treatment in acute bipolar depression J. Affect. Disord. 110 2008 70 74
11. S.J. Edwards, C.J. Smith Tolerability of atypical antipsychotics in the treatment of adults with schizophrenia or bipolar disorder: a mixed treatment comparison of randomized controlled trials Clin Ther. 31 Pt 1 2009 1345 1359
12. A. Fagiolini, K.N.R. Chengappa, I. Soreca, J. Chang Bipolar disorder and the metabolic syndrome Causal factors, psychiatric outcomes and economic burden. CNS Drugs 22 2008 655 669
13. K.N. Fountoulakis, E. Vieta Treatment of bipolar disorder: a systematic review of available data and clinical perspectives Int. J. Neuropsychopharmacol. 11 2008 999 1029
14. H. Grunze, E. Vieta, G.M. Goodwin, C. Bowden, R.W. Licht, H.-J. Moller, S. Kasper, WFSBP Task Force on Treatment Guidelines for Bipolar Disorders The World Federation of Societies of Biological Psychiatry (WFSBP): Update 2009 on the treatment of acute mania World J. Biol. Psychiatry 10 2009 85 116
15. H. Grunze, E. Vieta, G.M. Goodwin, C. Bowden, R.W. Licht, H.-J. Moller, S. Kasper, WFSBP Task Force on Treatment Guidelines for Bipolar Disorders The World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the biological treatment of bipolar disorders: Update 2010 on the treatment of acute bipolar depression World J. Biol. Psychiatry 11 2010 81 109
16. L.L. Judd, H.S. Akiskal, P.J. Schettler, J. Endicott, J. Maser, D.A. Solomon, A.C. Leon, J.A. Rice, M.B. Keller The long-term natural history of the weekly symptomatic status of bipolar I disorder Arch. Gen. Psychiatry 59 2002 530 537
17. P. Keck, R. Marcus, S. Tourkodimitris, M. Ali, A. Liebeskind, A. Saha, G. Ingenito, Aripiprazole Study Group A placebo controlled, double-blind study of the efficacy and safety of aripiprazole in patients with acute bipolar mania Am. J. Psychiatry 160 2003 1651 1658
18. P.E. Keck, J.R. Calabrese, R.D. McQuade, W.H. Carson, B.X. Carlson, L.M. Rollin, R.N. Marcus, R. Sanchez, for the Aripiprazole Study Group A randomized, double-blind, placebo-controlled 26-week trial of aripiprazole in recently manic patients with bipolar I disorder J. Clin. Psychiatry. 67 2006 626 637
19. P.E. Keck Jr., J.R. Calabrese, R.S. McIntyre, R.D. McQuade, W.H. Carson, J.M. Eudicone, B.X. Carlson, R.N. Marcus, R. Sanchez, for the Aripiprazole Study Group Aripiprazole monotherapy for maintenance therapy in bipolar I disorder: a 100-week, double-blind study versus placebo J. Clin. Psychiatry 68 2007 1480 1491
20. P.E. Keck, P.J. Orsulak, A.J. Cutler, R. Sanchez, A. Torbeyns, R.N. Marcus, R.D. McQuade, W.H. Carson, The CN138-135 Study Group Aripiprazole monotherapy in the treatment of acute bipolar I mania: A randomized, double-blind, placebo- and lithium-controlled study J. Affect. Disord. 112 2009 36 49
21. D.E. Kemp, W.S. Gilmer, J. Fleck, J.L. Straus, P.L. Dago, M. Karaffa Aripiprazole augmentation in treatment-resistant bipolar depression: early response and development of akathisia Prog. Neuropsychopharmacol. Biol. Psychiatry 31 2007 574 577
22. T.A. Ketter, P.W. Wang, R.A. Chandler, J.L. Culver, A.M. Alarcon Adjunctive aripiprazole in treatment-resistant bipolar depression Ann. Clin. Psychiatry. 18 2006 169 172
23. R.W. Kupka, L.L. Altshuler, W.A. Nolen, T. Suppes, D.A. Luckenbaugh, G.S. Leverich, M.A. Frye, P.E. Keck Jr., S.L. McElroy, H. Grunze, R.M. Post Three times more days depressed than manic or hypomanic in both bipolar I and bipolar II disorder Bipolar Disord. 9 2007 531 535
24. R.N. Marcus, R.D. McQuade, W.H. Carson, D. Hennicken, M. Fava, J.S. Simon, M.H. Trivedi, M.E. Thase, R.M. Berman The efficacy and safety of aripiprazole as adjunctive therapy in major depressive disorder: a second multicenter, randomized, double-blind, placebo-controlled study J. Clin. Psychopharmacol. 28 2008 156 165
25. S.L. McElroy, T. Suppes, M.A. Frye, L.L. Altshuler, K. Stanford, B. Martens, G.S. Leverich, R.M. Post, P.E. Keck Jr. Open-label aripiprazole in the treatment of acute bipolar depression: a prospective pilot trial J. Affect. Disord. 101 2007 275 281
26. E.E. Michalak, G. Murray, A.H. Young, R.W. Lam Burden of bipolar depression Impact of disorder and medications on quality of life. CNS Drugs. 22 2008 389 406
27. Nashat, M., Eudicone, J.M., Tran, Q.V., Pikalov, A., Owen, R., Carlson, B.X., 2009. Aripiprazole improves depressive episode symptoms of bipolar I patients experiencing more severe core depressive symptoms: a pooled analysis of two clinical trials. Eighth International Conference on Bipolar Disorder, June 25-27, Pittsburgh, PA, USA.
28. rd Meeting, May 22-26, New Orleans, LA.
29. R.M. Post, G.S. Leverich, L.L. Altshuler, M.A. Frye, T.M. Suppes, P.E. Keck Jr., S.L. McElroy, R. Kupka, W.A. Nolen, H. Grunze, J. Walden An overview of recent findings of the Stanley Foundation Bipolar Network (part I) Bipolar Disord. 5 2003 310 319
30. A. Quante, S. Zeugmann, A. Luborzewski, N. Schommer, J. Langosch, C. Born, I. Anghelescu, J. Wolf Aripiprazole as adjunct to a mood stabilizer and citalopram in bipolar depression: a randomized placebo-controlled pilot study Hum. Psychopharmacol. 25 2010 126 132
31. G. Sachs, R. Sanchez, R. Marcus, E. Stock, R. McQuade, W. Carson, N. Abou-Gharbia, C. Impellizzeri, S. Kaplita, L. Rollin, T. Iwamoto, Aripiprazole Study Group Aripiprazole in the treatment of acute manic or mixed episodes in patients with bipolar I disorder: a 3-week placebo-controlled study J Psychopharmacol. 20 2006 536 546
32. J. Sanchez-Moreno, A. Martinez-Aran, R. Tabarés-seisdedos, C. Torrent, E. Vieta, J.L. Ayuso-Mateos Functioning and disability in bipolar disorder: an extensive review Psychother. Psychosom. 78 2009 285 297
33. D.A. Shapiro, S. Renock, E. Arrington, L.A. Chiodo, L.X. Liu, D.R. Sibley, B.L. Roth, R. Mailman Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacology Neuropsychopharmacology 28 2003 1400 1411
34. K.N. Sokolski Adjunctive aripiprazole in bipolar I depression Ann. Pharmacother. 41 2007 35 40
35. T. Suppes, E. Vieta, S. Liu, M. Brecher, B Paulsson, Trial 127 Investigators Maintenance treatment for patients with bipolar I disorder: results from a North American study of quetiapine in combination with lithium or divalproex (trial 127) Am. J. Psychiatry 166 2009 476 488
36. M.E. Thase, W. Macfadden, R.H. Weisler, W. Chang, B. Paulsson, A. Khan, J.R. Calabrese, BOLDER II Study Group Efficacy of quetiapine monotherapy in bipolar I and II depression: a double-blind, placebo-controlled study (the BOLDER II study) J. Clin. Psychopharmacol. 26 2006 600 609
37. M.E. Thase, A. Jonas, A. Khan, C.L. Bowden, X. Wu, R.D. McQuade, W.H. Carson, R.N. Marcus, R. Owen Aripiprazole monotherapy in non-psychotic bipolar I depression Clin. Psycho. Pharmacol. 28 2008 13 20
38. M. Tohen, E. Vieta, J. Calabrese, T.A. Ketter, G. Sachs, C. Bowden, P.B. Mitchell, R. Centorrino, R. Risser, R.W. Baker, A.R. Evans, K. Beymer, S. Dube, G.D. Tollefson, A. Breier Efficacy of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression Arch. Gen. Psychiatry 60 2003 1079 1088
39. M. Tohen, K.N. Chengappa, T. Suppes, R.W. Baker, C.A. Zarate, C.L. Bowden, G.S. Sachs, D.J. Kupfer, S.N. Ghaemi, P.D. Feldman, R.C. Risser, A.R. Evans, J.R. Calabrese Relapse prevention in bipolar I disorder: 18-month comparison of olanzapine plus mood stabilizer v. mood stabiliser alone Br. J. Psychiatr. 184 2004 337 345
40. E. Vieta, X. Carné The use of placebo in clinical trials on bipolar disorder: a new approach for an old debate Psychother. Psychosom. 74 2005 10 16
41. E. Vieta, T. Suppes, I. Eggens, I. Persson, B. Paulsson, M. Brecher Efficacy and safety of quetiapine in combination with lithium or divalproex for maintenance of patients with bipolar I disorder (international trial 126) J. Affect. Disord. 109 2008 251 263
42. E. Vieta, C. T-Joen, RD. McQuade, W.H. Carson Jr., R.N. Marcus, R. Sanchez, R. Owen, L. Nameche Efficacy of adjunctive aripiprazole to either valproate or lithium in bipolar mania patients partially nonresponsive to valproate/lithium monotherapy: a placebo-controlled study Am. J. Psychiatr. 165 2008 1316 1325
43. E. Vieta, R. Owen, C. Baudelet, R.D. McQuade, R. Sanchez, R.N. Marcus Assessment of safety, tolerability and effectiveness of adjunctive aripiprazole to lithium/valproate in bipolar mania: a 46-week, open-label extension following a 6-week double-blind study Curr. Med. Res. Opin. 26 2010 1485 1496
44. L.N. Yatham, S.H. Kennedy, C. O'Donovan, S. Parikh, G. MacQueen, R. McIntyre, V. Sharma, P. Silverstone, M. Alda, P. Baruch, S. Beaulieu, A. Daigneault, R. Milev, T. Young, A. Ravindran, A. Schaffer, M. Connolly, C.P. Gorman Canadian Network for Mood and Anxiety Treatments (CANMAT) guidelines for the management of patients with bipolar disorder: consensus and controversies Bipolar Disord. 7 Suppl 3 2005 5 69
45. L.N. Yatham, S.H. Kennedy, C. O'Donovan, S.V. Parikh, G. MacQueen, R.S. McIntyre, V. Sharma, S Beaulieu, for CANMAT guidelines group Canadian Network for Mood and Anxiety Treatments (CANMAT) guidelines for the management of patients with bipolar disorder: update 200 Bipolar Disord. 8 2006 721 739
46. L.N. Yatham, S.H. Kennedy, A. Schaffer, S.V. Parikh, S. Beaulieu, C. O'Donovan, G. MacQueen, R.S. McIntyre, V. Sharma, A. Ravindran, L.T. Young, A.H. Young, M. Alda, R. Milev, E. Vieta, J.R. Calabrese, M. Berk, K. Ha, R. Kapczinski Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2009 Bipolar Disord. 11 2009 225 255