Microneedles with intrinsic immunoadjuvant properties: Microfabrication, protein stability, and modulated release

Pharmaceutical Research

Volumn 28, Issue 1, 2011, Pages 58-65

  Andrianov, Alexander K ^a   Marin, Alexander ^a   Decollibus, Daniel P ^a  

^a Apogee Technology Inc   (United States)

Author keywords

intradermal immunization; microneedles; polyphosphazenes; protein stability; vaccine adjuvants

Indexed keywords

CARBOXYMETHYLCELLULOSE; IMMUNOLOGICAL ADJUVANT; POLY[DI(CARBOXYLATOPHENOXY)PHOSPHAZENE]; POLYELECTROLYTE; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; ENCAPSULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NANOFABRICATION; NEEDLE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEIN STABILITY; VISCOSITY;

ADJUVANTS, IMMUNOLOGIC; CHEMISTRY, PHARMACEUTICAL; IMMUNIZATION; INJECTIONS, INTRADERMAL; MICROINJECTIONS; NEEDLES; ORGANOPHOSPHORUS COMPOUNDS; POLYMERS; PROTEIN STABILITY; SERUM ALBUMIN, BOVINE; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL; TIME FACTORS; VACCINES;

EID: 78651231347     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-010-0133-7     Document Type: Article

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