Intermittent fasting modulation of the diabetic syndrome in sand rats. III. Post-mortem investigations

International Journal of Molecular Medicine

Volumn 27, Issue 1, 2011, Pages 95-102

  Belkacemi, Louiza ^a   Selselet Attou, Ghalem ^a   Bulur, Nurdan ^b   Louchami, Karim ^b   Sener, Abdullah ^b   Malaisse, Willy J ^b  

^a UNIVERSITY OF MOSTAGANEM   (Algeria)

^b UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

Body, liver and pancreas weight; Cholesterol and triglyceride; Haemoglobin A1c; Insulin; Intermittent fasting; Liver triglyceride and phospholipid; Pancreatic insulin and glut2; Plasma glucose; Sand rats

Indexed keywords

CHOLESTEROL; FAT DROPLET; GLUCOSE; GLUCOSE TRANSPORTER 2; HEMOGLOBIN A1C; INSULIN; PHOSPHOLIPID; TRIACYLGLYCEROL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIABETES MELLITUS; DIET RESTRICTION; FOOD INTAKE; GLUCOSE BLOOD LEVEL; HEMOGLOBIN BLOOD LEVEL; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; LIPID LIVER LEVEL; LIVER WEIGHT; NONHUMAN; PANCREAS ISLET; PHOSPHOLIPID BLOOD LEVEL; PRIORITY JOURNAL; PSAMMOMYS OBESUS; RAT; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; BLOOD GLUCOSE; CHOLESTEROL; DIABETES MELLITUS; DIET; EATING; FASTING; GERBILLINAE; INSULIN; INSULIN RESISTANCE; LIVER; ORGAN SIZE; PANCREAS; PHOSPHOLIPIDS; POSTMORTEM CHANGES; TRIGLYCERIDES;

EID: 78651109311     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2010.556     Document Type: Article

References (15)

1. Yki-Jarvinen H: Fat in the liver and insulin resistance. Ann Med 37: 347-356, 2005.
2. Belkacemi L, Selselet-Attou G, Sener A and Malaisse WJ: Intermittent fasting modulation of the diabetic syndrome in sand rats. I. Background information and experimental design. Metab Funct Res Diab 2: 5-8, 2009.
3. Belkacemi L, Selselet-Attou G, Louchami K, Sener A and Malaisse WJ: Intermittent fasting modulation of the diabetic syndrome in sand rats. II. In vivo investigations. Int J Mol Med 26: 759-765, 2010.
4. Bergmeyer HU and Berndt E: Glucose determination with glucose oxidase and peroxidase. In: Methods of Enzymatic Analysis. Bergmeyer HU (ed). Academic Press, New York, pp1205-1215, 1974.
5. Ersser RS, Barlow GB, Drew RG and Hjelm M: Packing materials suitable for rapid, analytical, low-pressure chromatography of hemoglobins on midget columns. Biomed Chromatogr 1: 183-188, 1986.
6. Leclercq-Meyer V, Marchand J, Woussen-Colle MC, Giroix M-H and Malaisse WJ: Multiple effects of leucine on glucagon, insulin and somatostatin secretion from the perfused rat pancreas. Endocrinology 116: 1168-1174, 1985.
7. Folch J, Lees M and Sloane-Stanley GH: A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226: 497-509, 1957.
8. Hsu SM, Raine L and Fanger H: Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem 29: 577-580, 1981.
9. den Boer M, Voshol PJ, Kuipers F, Havekes LM and Romijn JA: Hepatic steatosis: a mediator of the metabolic syndrome. Lessons from animal models. Arterioscler Thromb Vasc Biol 24: 644-649, 2004.
10. Bacon BR, Farahvash MJ and Janney CG: Nonalcoholic steatohepatitis: an expanded clinical entity. Gastroenterology 107: 1103-1109, 1994.
11. Scoppola A, Montecchi FR, Menzenger G and Lala A: Urinary mevalonate excretion rate in type 2 diabetes: role of metabolic control. Atherosclerosis 1565: 357-361, 2001.
12. Simonen P, Gylling H, Howard AN and Miettinen TA: Introducing a new component of the metabolic syndrome: low cholesterol absorption. Am J Clin Nutr 72: 82-88, 2000.
13. Malaisse WJ, Like AA, Malaisse-Lagae F, Gleason RE and Soeldner JS: Insulin secretion in vitro by the pancreas of the sand rats (Psammomys obesus). Diabetes 17: 752-759, 1968.
14. Kaiser N, Yuli M, Üçkaya G, Oprescu AI, Berthoult M-F, Kargar C, Donath MY, Cerasi E and Ktorza A: Dynamic changes in β-cell mass and pancreatic insulin during the evolution of nutrition-dependent diabetes in Psammomys obesus. Diabetes 54: 138-145, 2005.
15. Malaisse WJ, Malaisse-Lagae F and Wright PH: Effect of fasting upon insulin secretion in the rat. Am J Physiol 213: 843-848, 1967.